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The map label for this gene is tagA

Identifier: 16080628

GI number: 16080628

Start: 3681370

End: 3682140

Strand: Direct

Name: tagA

Synonym: BSU35750

Alternate gene names: 16080628

Gene position: 3681370-3682140 (Clockwise)

Preceding gene: 16080620

Following gene: 16080629

Centisome position: 87.33

GC content: 36.71

Gene sequence:

>771_bases
ATGCAAACAGAGACTATTCACAATATTCCTTATGTTAACAGTAACTTAACATCATTTATCGATTACCTAGAGAAACATTA
TATTGATCAAAAGATTGGTGCTGTCATTTCCACAGTCAACCCTGAAATTGCATTTGCAGCTATTAAAGATCGGGACTACT
TTGATGTACTATCTTCTTCAAACTTCATTTTGCCTGATGGGATCGGTGTAGTCATGATGTCACGTTTGACTAACAACAGG
CTTCAGTCCCGAATCGCAGGTTACGATGTTTTTAAAGAACTTCTGGGCGTTGCTAACAAAAAGAAAAAACGCATATTTCT
GTACGGTGCGAAGAAAGATGTTATAAAAGGTGTTGTATCCAAAATTTCTTCTGAATACCCAAACATTAAAATCGCAGGTT
ATTCAGACGGTTATGTTCAAGATCGCACCCTAGTGGCAAAACAAATTGCAAGAGCAAATCCTGACATGGTATTCGTAGCT
TTAGGGTATCCTCATCAAGAGAAATTCATTCATAACTACAGACACTTGTTCCCTAAAGCCGTATCTATAGGTCTAGGAGG
AAGCTTTGATGTATTTAGCGGTAATGTCAAACGGGCCCCTTCCTGGATGATACGTTTAAATTTAGAATGGTTCTACCGGT
TAATCTTGAATCCATGGCGATGGAAAAGAATGCTTAGCATCCCAAAATATGCTTTAACGGTTTTAAAAGAAGAAAAAAAC
AAAAAAACTTTCTATCCAAAGCCTGAAAAAGATCATACAAAACAGATTTAA

Upstream 100 bases:

>100_bases
TGAAGATTTATGTTAAAATATAAGGTAGCTTGATTTTGCTTTTAGAAACTCTCGGTTTTTAACTATATAAATAGAATCTT
AAAGGAAGGAGGAGCCAGAC

Downstream 100 bases:

>100_bases
AAACAAAACTTTCAAATAAATGGATGATAAAAATGAAAATAAGATCACTACTGGCGAATTGCTATTTGTATTTTTTATCA
GCAATCGCCTTTTTTCTGCA

Product: N-acetylmannosamine (ManNAc) C4 hydroxyl of a membrane-anchored N-acetylglucosaminyl diphospholipid (GlcNAc-pp-undecaprenyl, lipid I) glycosyltransferase

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MQTETIHNIPYVNSNLTSFIDYLEKHYIDQKIGAVISTVNPEIAFAAIKDRDYFDVLSSSNFILPDGIGVVMMSRLTNNR
LQSRIAGYDVFKELLGVANKKKKRIFLYGAKKDVIKGVVSKISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVA
LGYPHQEKFIHNYRHLFPKAVSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNPWRWKRMLSIPKYALTVLKEEKN
KKTFYPKPEKDHTKQI

Sequences:

>Translated_256_residues
MQTETIHNIPYVNSNLTSFIDYLEKHYIDQKIGAVISTVNPEIAFAAIKDRDYFDVLSSSNFILPDGIGVVMMSRLTNNR
LQSRIAGYDVFKELLGVANKKKKRIFLYGAKKDVIKGVVSKISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVA
LGYPHQEKFIHNYRHLFPKAVSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNPWRWKRMLSIPKYALTVLKEEKN
KKTFYPKPEKDHTKQI
>Mature_256_residues
MQTETIHNIPYVNSNLTSFIDYLEKHYIDQKIGAVISTVNPEIAFAAIKDRDYFDVLSSSNFILPDGIGVVMMSRLTNNR
LQSRIAGYDVFKELLGVANKKKKRIFLYGAKKDVIKGVVSKISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVA
LGYPHQEKFIHNYRHLFPKAVSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNPWRWKRMLSIPKYALTVLKEEKN
KKTFYPKPEKDHTKQI

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential)

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family

Homologues:

Organism=Escherichia coli, GI2367289, Length=212, Percent_Identity=32.5471698113208, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAGA_BACSU (P27620)

Other databases:

- EMBL:   M57497
- EMBL:   AL009126
- PIR:   B49757
- RefSeq:   NP_391456.1
- EnsemblBacteria:   EBBACT00000001304
- GeneID:   936810
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU35750
- NMPDR:   fig|224308.1.peg.3582
- GenoList:   BSU35750
- GeneTree:   EBGT00050000002593
- HOGENOM:   HBG685240
- OMA:   ENFIQNN
- PhylomeDB:   P27620
- ProtClustDB:   CLSK887976
- BioCyc:   BSUB:BSU35750-MONOMER
- BioCyc:   MetaCyc:MONOMER-8807
- BRENDA:   2.4.1.187
- InterPro:   IPR004629
- TIGRFAMs:   TIGR00696

Pfam domain/function: PF03808 Glyco_tran_WecB

EC number: =2.4.1.187

Molecular weight: Translated: 29500; Mature: 29500

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTETIHNIPYVNSNLTSFIDYLEKHYIDQKIGAVISTVNPEIAFAAIKDRDYFDVLSSS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCC
NFILPDGIGVVMMSRLTNNRLQSRIAGYDVFKELLGVANKKKKRIFLYGAKKDVIKGVVS
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHH
KISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVALGYPHQEKFIHNYRHLFPKA
HHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
VSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNPWRWKRMLSIPKYALTVLKEEKN
HEECCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHCC
KKTFYPKPEKDHTKQI
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTETIHNIPYVNSNLTSFIDYLEKHYIDQKIGAVISTVNPEIAFAAIKDRDYFDVLSSS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCC
NFILPDGIGVVMMSRLTNNRLQSRIAGYDVFKELLGVANKKKKRIFLYGAKKDVIKGVVS
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHH
KISSEYPNIKIAGYSDGYVQDRTLVAKQIARANPDMVFVALGYPHQEKFIHNYRHLFPKA
HHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
VSIGLGGSFDVFSGNVKRAPSWMIRLNLEWFYRLILNPWRWKRMLSIPKYALTVLKEEKN
HEECCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHCC
KKTFYPKPEKDHTKQI
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717