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The map label for this gene is coaE

Identifier: 16079958

GI number: 16079958

Start: 2970922

End: 2971515

Strand: Reverse

Name: coaE

Synonym: BSU29060

Alternate gene names: 16079958

Gene position: 2971515-2970922 (Counterclockwise)

Preceding gene: 255767670

Following gene: 16079955

Centisome position: 70.49

GC content: 43.27

Gene sequence:

>594_bases
TTGACCTTAGTCATTGGTTTAACGGGAGGAATAGCTAGCGGCAAAAGCACGGTAGCCAATATGCTGATTGAAAAAGGAAT
AACAGTTATAGATGCAGATATCATTGCAAAACAAGCGGTAGAAAAAGGGATGCCGGCCTACCGGCAAATCATTGACGAAT
TCGGTGAAGACATACTGCTCTCAAATGGCGATATAGATAGAAAAAAGCTTGGAGCGCTGGTATTTACAAATGAACAAAAA
CGTCTCGCTTTAAATGCAATTGTTCATCCCGCAGTCAGGCAGGAAATGCTCAATCGCCGTGATGAAGCCGTTGCAAATCG
GGAGGCATTTGTTGTATTGGATATCCCGCTATTGTTCGAAAGCAAATTGGAATCATTGGTTGATAAAATTATTGTGGTCA
GTGTGACAAAAGAGCTTCAACTGGAACGTCTGATGAAGCGCAATCAGCTGACAGAAGAAGAAGCAGTCAGCCGTATCCGC
TCTCAAATGCCCTTAGAGGAAAAAACAGCAAGAGCAGATCAAGTCATTGATAACAGCGGCACGCTTGAAGAGACCAAAAG
GCAGCTTGATGAAATCATGAACAGCTGGGCATAA

Upstream 100 bases:

>100_bases
TTTTCTGTCTAAGTGGAAATGGATCGATAAAATGGCGTTTTTGCCGGGGCTTCTATTAATCACGATTGGGCTCTGGAAAT
TGTAAAAAGGAGTGGATCTC

Downstream 100 bases:

>100_bases
TACAAAAAACACCGTTCATATTGAACGGTGTTTTTTGGCCATTAAAAATCAAAGTTGTCCGGATCAGGACCGACGCGCAA
GTTTTCATTCAGTGCATCGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTLVIGLTGGIASGKSTVANMLIEKGITVIDADIIAKQAVEKGMPAYRQIIDEFGEDILLSNGDIDRKKLGALVFTNEQK
RLALNAIVHPAVRQEMLNRRDEAVANREAFVVLDIPLLFESKLESLVDKIIVVSVTKELQLERLMKRNQLTEEEAVSRIR
SQMPLEEKTARADQVIDNSGTLEETKRQLDEIMNSWA

Sequences:

>Translated_197_residues
MTLVIGLTGGIASGKSTVANMLIEKGITVIDADIIAKQAVEKGMPAYRQIIDEFGEDILLSNGDIDRKKLGALVFTNEQK
RLALNAIVHPAVRQEMLNRRDEAVANREAFVVLDIPLLFESKLESLVDKIIVVSVTKELQLERLMKRNQLTEEEAVSRIR
SQMPLEEKTARADQVIDNSGTLEETKRQLDEIMNSWA
>Mature_196_residues
TLVIGLTGGIASGKSTVANMLIEKGITVIDADIIAKQAVEKGMPAYRQIIDEFGEDILLSNGDIDRKKLGALVFTNEQKR
LALNAIVHPAVRQEMLNRRDEAVANREAFVVLDIPLLFESKLESLVDKIIVVSVTKELQLERLMKRNQLTEEEAVSRIRS
QMPLEEKTARADQVIDNSGTLEETKRQLDEIMNSWA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=188, Percent_Identity=45.7446808510638, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI191252795, Length=188, Percent_Identity=45.7446808510638, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI110227607, Length=194, Percent_Identity=33.5051546391753, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI205277394, Length=194, Percent_Identity=33.5051546391753, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI110227605, Length=194, Percent_Identity=33.5051546391753, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI110227603, Length=194, Percent_Identity=33.5051546391753, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI110227601, Length=194, Percent_Identity=33.5051546391753, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1786292, Length=181, Percent_Identity=40.8839779005525, Blast_Score=137, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17554944, Length=200, Percent_Identity=39.5, Blast_Score=156, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI25143409, Length=188, Percent_Identity=31.3829787234043, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=44.3877551020408, Blast_Score=157, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=41.4507772020725, Blast_Score=166, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24658602, Length=188, Percent_Identity=37.2340425531915, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_BACSU (O34932)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   A69988
- RefSeq:   NP_390784.1
- ProteinModelPortal:   O34932
- SMR:   O34932
- EnsemblBacteria:   EBBACT00000000655
- GeneID:   937388
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29060
- NMPDR:   fig|224308.1.peg.2909
- GenoList:   BSU29060
- GeneTree:   EBGT00050000001187
- HOGENOM:   HBG650290
- OMA:   VVVYCDP
- PhylomeDB:   O34932
- ProtClustDB:   PRK00081
- BioCyc:   BSUB:BSU29060-MONOMER
- BRENDA:   2.7.1.24
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 22014; Mature: 21883

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVIGLTGGIASGKSTVANMLIEKGITVIDADIIAKQAVEKGMPAYRQIIDEFGEDILL
CEEEEEECCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHCCCEEE
SNGDIDRKKLGALVFTNEQKRLALNAIVHPAVRQEMLNRRDEAVANREAFVVLDIPLLFE
CCCCCCHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHH
SKLESLVDKIIVVSVTKELQLERLMKRNQLTEEEAVSRIRSQMPLEEKTARADQVIDNSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
TLEETKRQLDEIMNSWA
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLVIGLTGGIASGKSTVANMLIEKGITVIDADIIAKQAVEKGMPAYRQIIDEFGEDILL
EEEEEECCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHCCCEEE
SNGDIDRKKLGALVFTNEQKRLALNAIVHPAVRQEMLNRRDEAVANREAFVVLDIPLLFE
CCCCCCHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHH
SKLESLVDKIIVVSVTKELQLERLMKRNQLTEEEAVSRIRSQMPLEEKTARADQVIDNSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
TLEETKRQLDEIMNSWA
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377