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The map label for this gene is hrcA

Identifier: 16079603

GI number: 16079603

Start: 2628606

End: 2629637

Strand: Reverse

Name: hrcA

Synonym: BSU25490

Alternate gene names: 16079603

Gene position: 2629637-2628606 (Counterclockwise)

Preceding gene: 255767587

Following gene: 16079602

Centisome position: 62.38

GC content: 41.57

Gene sequence:

>1032_bases
ATGTTAACAAATCGTCAGCTGCTGATCCTTCAGGTTATAATCAACGATTTTATTAAATCGGCACAGCCGGTGGGATCAAG
AACTCTTTCGAAAAAAGATGAAATCACATTTAGCTCTGCAACAATAAGAAACGAGATGGCTGACTTGGAGGAATTGGGCT
TTATTGAAAAAACCCATTCATCCTCAGGACGTGTTCCGTCAGAAAAAGGGTATCGGTACTATGTTGACCATTTGCTGTCA
CCCGTCAAATTGACGAAAAGCGACCTGGACCAAATCCACTCGATCTTCAAAGAGAAAATTTTCGAGCTGGAGAAGACAGT
TCAAAAATCAGCGCAAATTTTGTCCGATCTGACGAATTACACATCCATCGTACTCGGGCCGAAGTTGAGTGAGAATTACC
TTAAACAGATTCAAATCATTCCGATTCAGCCTGATATGGCGGTAGCGATTCTCGTTACCAATACGGGGCATGTGGAAAAC
AAAACGATTAACTTTCCGACCAAAATGGATCTGTCTGATATTGAAAAACTGGTAAATATACTGAACGACCGTTTAAGCGG
CGTTCCAATGGATGAACTGAATGAGCGCATATTTAAAGAAGTTGTCATGTACCTAAGACAGCACATTAAAAACTATGACA
ATATACTCGACGCGCTTCGTTCAACCTTTCATTCCACAAATCACGTTGAAAAGTTGTTTTTTGGCGGGAAAATCAATATG
CTGAACCAGCCTGAGTTCCATGATATCACCCGAGTTCGGTCGCTGCTTTCATTAATTGAGAAAGAACAGGATGTTTTAAA
GCTGGTTCAATCCCCGCACACGGGAATTTCGATTAAAATCGGAAAAGAAAACGACTATGAAGAGATGGAAAATTGCAGTC
TGATTACGGCTTCTTATTCCGTAGACCAGAAGCAGATCGGCTCAATTGCGATTATCGGCCCGACCCGCATGAATTATTCC
AGGGTTGTCAGCCTGCTTCAGCATGTGACTTCGGACTTGTCAAAAGCATTAACAAGTCTGTATGATGAATAA

Upstream 100 bases:

>100_bases
CTTTTTTGGGTGAGTTATAATTGACATTTTTCTTGTGGTTTGATACTTTTGTTATAGAATTAGCACTCGCTTATTGAGAG
TGCTAACAGAGGTGATGATG

Downstream 100 bases:

>100_bases
GGGAATTTTGGCAAATTTTATCGAAGGGCAGCACCTGTCCTTCTCCTTACACTTTGAGGGAGGTGAACACAATGTCAGAA
GAAAAACAAACCGTTGAACA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLTNRQLLILQVIINDFIKSAQPVGSRTLSKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRYYVDHLLS
PVKLTKSDLDQIHSIFKEKIFELEKTVQKSAQILSDLTNYTSIVLGPKLSENYLKQIQIIPIQPDMAVAILVTNTGHVEN
KTINFPTKMDLSDIEKLVNILNDRLSGVPMDELNERIFKEVVMYLRQHIKNYDNILDALRSTFHSTNHVEKLFFGGKINM
LNQPEFHDITRVRSLLSLIEKEQDVLKLVQSPHTGISIKIGKENDYEEMENCSLITASYSVDQKQIGSIAIIGPTRMNYS
RVVSLLQHVTSDLSKALTSLYDE

Sequences:

>Translated_343_residues
MLTNRQLLILQVIINDFIKSAQPVGSRTLSKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRYYVDHLLS
PVKLTKSDLDQIHSIFKEKIFELEKTVQKSAQILSDLTNYTSIVLGPKLSENYLKQIQIIPIQPDMAVAILVTNTGHVEN
KTINFPTKMDLSDIEKLVNILNDRLSGVPMDELNERIFKEVVMYLRQHIKNYDNILDALRSTFHSTNHVEKLFFGGKINM
LNQPEFHDITRVRSLLSLIEKEQDVLKLVQSPHTGISIKIGKENDYEEMENCSLITASYSVDQKQIGSIAIIGPTRMNYS
RVVSLLQHVTSDLSKALTSLYDE
>Mature_343_residues
MLTNRQLLILQVIINDFIKSAQPVGSRTLSKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRYYVDHLLS
PVKLTKSDLDQIHSIFKEKIFELEKTVQKSAQILSDLTNYTSIVLGPKLSENYLKQIQIIPIQPDMAVAILVTNTGHVEN
KTINFPTKMDLSDIEKLVNILNDRLSGVPMDELNERIFKEVVMYLRQHIKNYDNILDALRSTFHSTNHVEKLFFGGKINM
LNQPEFHDITRVRSLLSLIEKEQDVLKLVQSPHTGISIKIGKENDYEEMENCSLITASYSVDQKQIGSIAIIGPTRMNYS
RVVSLLQHVTSDLSKALTSLYDE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39028; Mature: 39028

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNRQLLILQVIINDFIKSAQPVGSRTLSKKDEITFSSATIRNEMADLEELGFIEKTHS
CCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRVPSEKGYRYYVDHLLSPVKLTKSDLDQIHSIFKEKIFELEKTVQKSAQILSDLTNY
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIVLGPKLSENYLKQIQIIPIQPDMAVAILVTNTGHVENKTINFPTKMDLSDIEKLVNI
HHEEECCCCCHHHHHCEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHH
LNDRLSGVPMDELNERIFKEVVMYLRQHIKNYDNILDALRSTFHSTNHVEKLFFGGKINM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEECC
LNQPEFHDITRVRSLLSLIEKEQDVLKLVQSPHTGISIKIGKENDYEEMENCSLITASYS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCEEEEEECC
VDQKQIGSIAIIGPTRMNYSRVVSLLQHVTSDLSKALTSLYDE
CCHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTNRQLLILQVIINDFIKSAQPVGSRTLSKKDEITFSSATIRNEMADLEELGFIEKTHS
CCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRVPSEKGYRYYVDHLLSPVKLTKSDLDQIHSIFKEKIFELEKTVQKSAQILSDLTNY
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIVLGPKLSENYLKQIQIIPIQPDMAVAILVTNTGHVENKTINFPTKMDLSDIEKLVNI
HHEEECCCCCHHHHHCEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHH
LNDRLSGVPMDELNERIFKEVVMYLRQHIKNYDNILDALRSTFHSTNHVEKLFFGGKINM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEECC
LNQPEFHDITRVRSLLSLIEKEQDVLKLVQSPHTGISIKIGKENDYEEMENCSLITASYS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCEEEEEECC
VDQKQIGSIAIIGPTRMNYSRVVSLLQHVTSDLSKALTSLYDE
CCHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA