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The map label for this gene is bcsA

Identifier: 16079263

GI number: 16079263

Start: 2316956

End: 2318053

Strand: Reverse

Name: bcsA

Synonym: BSU22050

Alternate gene names: 16079263

Gene position: 2318053-2316956 (Counterclockwise)

Preceding gene: 16079264

Following gene: 16079262

Centisome position: 54.99

GC content: 45.36

Gene sequence:

>1098_bases
ATGGCGTTTATTTTATCCATTGGAACAAGTCTTCCTGCGTATAATGTAAACCAAGAGAAAGCGGCCGAGTTCGCCCGCTA
TATGTTTCAGCATTCTTTTAAGGATATTGACAGGCTGTTATCCTCCTTTAAAAACGGGCAAATCCATTCGAGACAGTTTG
TTAAGCCGATTGAATGGTATAAAGAGGGGCACAGCTTTGAAGAAAAAAATCAAATATACATAGAAGAAACACTTAAACAC
AGCAGAGCGGCTGTTCGTGAGTGCCTCTCTCATCCGGAATTTTTTCAAGAAGCCATTCCTTATGAGAAAGTGGAAGCTGT
TTTTTTCGTCTCCAGTACAGGTCTTTCCACACCGAGTATCGAGGCGCGGCTTATGAATGAACTTCCGTTTTCTCCATATA
CGAAGCGGATTCCGATTTGGGGGCTTGGCTGTGCAGGAGGAGCCAGCGGACTTGCGCGTGCAGCCGAATACTGCAAAGCG
TATCCTGAGGCTTTTGTGCTTGTCATTTCTGCCGAGCTGTGCAGCCTGACATTCCAGCCGGAAGATAAAACAAAAAGCAA
TCTGATCGGCACCTCGCTTTTTGGTGACGGCATTGCCGCAGCTTTATTATGCGGAGAGAAGGCGGACCGCAGGGTGTCAA
AGCTGAAGCTTGCGCCGAAGATAATGGACGCCCAATCTGTTTTGATGAAACAATCAGAAGATGTCATGGGCTGGGACTTT
ACCGATCAAGGATTCAAAGTCATTTTCTCACGAGACATTCCGACCTTGGTGGAAAAATGGCTCAAAACAAATGTACAGAT
TTTTTTGGACAAACATAAGCTGTCATTCCATGATATCAGTGTTTTTTTGGCGCATCCAGGCGGAAAAAAAGTGATCGATG
CATACATCAAAAGTCTCGGGCTGTCGTCAGAAAAGCTTTCATCTGCGCAAAGCATTTTGCAAAAGCACGGAAATATGTCT
TCAGCCACAATCTTGTATGTGATCAAAGACCATCTGCAGAACGGACATAAAAAGGAAGCTGAACGAGGACTGATTGGCGC
ATTAGGGCCGGGTTTCTCATCAGAGTTGCTATTATTCAGCTGGGAAAAGGGGGCCTGA

Upstream 100 bases:

>100_bases
CTCGCTGAACAAAAAACAGCAGTCTAACTCCGCCGCGGCGGAGTTTTTTTTGCATATAAAAAAGATTGTTGCGGCACAAT
GTATGCAAAGAGGTGATCGC

Downstream 100 bases:

>100_bases
CTCATGTTTTGGTTGTTGATCGCCATTCTCATTGTTCAAAGAGCAGCAGAAATGGCAGTGGCCAGGCAAAACGAACAAAA
GGTAAAGAAGCAAGGAGCAA

Product: terpene family molecule synthase

Products: NA

Alternate protein names: Naringenin-chalcone synthase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MAFILSIGTSLPAYNVNQEKAAEFARYMFQHSFKDIDRLLSSFKNGQIHSRQFVKPIEWYKEGHSFEEKNQIYIEETLKH
SRAAVRECLSHPEFFQEAIPYEKVEAVFFVSSTGLSTPSIEARLMNELPFSPYTKRIPIWGLGCAGGASGLARAAEYCKA
YPEAFVLVISAELCSLTFQPEDKTKSNLIGTSLFGDGIAAALLCGEKADRRVSKLKLAPKIMDAQSVLMKQSEDVMGWDF
TDQGFKVIFSRDIPTLVEKWLKTNVQIFLDKHKLSFHDISVFLAHPGGKKVIDAYIKSLGLSSEKLSSAQSILQKHGNMS
SATILYVIKDHLQNGHKKEAERGLIGALGPGFSSELLLFSWEKGA

Sequences:

>Translated_365_residues
MAFILSIGTSLPAYNVNQEKAAEFARYMFQHSFKDIDRLLSSFKNGQIHSRQFVKPIEWYKEGHSFEEKNQIYIEETLKH
SRAAVRECLSHPEFFQEAIPYEKVEAVFFVSSTGLSTPSIEARLMNELPFSPYTKRIPIWGLGCAGGASGLARAAEYCKA
YPEAFVLVISAELCSLTFQPEDKTKSNLIGTSLFGDGIAAALLCGEKADRRVSKLKLAPKIMDAQSVLMKQSEDVMGWDF
TDQGFKVIFSRDIPTLVEKWLKTNVQIFLDKHKLSFHDISVFLAHPGGKKVIDAYIKSLGLSSEKLSSAQSILQKHGNMS
SATILYVIKDHLQNGHKKEAERGLIGALGPGFSSELLLFSWEKGA
>Mature_364_residues
AFILSIGTSLPAYNVNQEKAAEFARYMFQHSFKDIDRLLSSFKNGQIHSRQFVKPIEWYKEGHSFEEKNQIYIEETLKHS
RAAVRECLSHPEFFQEAIPYEKVEAVFFVSSTGLSTPSIEARLMNELPFSPYTKRIPIWGLGCAGGASGLARAAEYCKAY
PEAFVLVISAELCSLTFQPEDKTKSNLIGTSLFGDGIAAALLCGEKADRRVSKLKLAPKIMDAQSVLMKQSEDVMGWDFT
DQGFKVIFSRDIPTLVEKWLKTNVQIFLDKHKLSFHDISVFLAHPGGKKVIDAYIKSLGLSSEKLSSAQSILQKHGNMSS
ATILYVIKDHLQNGHKKEAERGLIGALGPGFSSELLLFSWEKGA

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Catalyzes The First Condensation Reaction Which Initiates Fatty Acid Synthesis And May Therefore Play A Role In Governing The

COG id: COG3424

COG function: function code Q; Predicted naringenin-chalcone synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chalcone/stilbene synthases family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BCSA_BACSU (P54157)

Other databases:

- EMBL:   L77246
- EMBL:   AL009126
- EMBL:   X83878
- PIR:   A69593
- RefSeq:   NP_390087.1
- ProteinModelPortal:   P54157
- SMR:   P54157
- EnsemblBacteria:   EBBACT00000003963
- GeneID:   939069
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU22050
- NMPDR:   fig|224308.1.peg.2210
- GenoList:   BSU22050
- GeneTree:   EBGT00050000001268
- HOGENOM:   HBG588210
- OMA:   DIMGWDV
- ProtClustDB:   CLSK872772
- BioCyc:   BSUB:BSU22050-MONOMER
- BRENDA:   2.3.1.74
- InterPro:   IPR012328
- InterPro:   IPR018088
- InterPro:   IPR001099
- InterPro:   IPR011141
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- PIRSF:   PIRSF000451

Pfam domain/function: PF02797 Chal_sti_synt_C; PF00195 Chal_sti_synt_N; SSF53901 Thiolase-like

EC number: =2.3.1.74

Molecular weight: Translated: 40713; Mature: 40582

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00441 CHALCONE_SYNTH

Important sites: ACT_SITE 144-144

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFILSIGTSLPAYNVNQEKAAEFARYMFQHSFKDIDRLLSSFKNGQIHSRQFVKPIEWY
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KEGHSFEEKNQIYIEETLKHSRAAVRECLSHPEFFQEAIPYEKVEAVFFVSSTGLSTPSI
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHEEEEEEEECCCCCCCCH
EARLMNELPFSPYTKRIPIWGLGCAGGASGLARAAEYCKAYPEAFVLVISAELCSLTFQP
HHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHEEHEEEHHHHHEECCC
EDKTKSNLIGTSLFGDGIAAALLCGEKADRRVSKLKLAPKIMDAQSVLMKQSEDVMGWDF
CCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDQGFKVIFSRDIPTLVEKWLKTNVQIFLDKHKLSFHDISVFLAHPGGKKVIDAYIKSLG
CCCCCEEEEECCCHHHHHHHHHCCEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHC
LSSEKLSSAQSILQKHGNMSSATILYVIKDHLQNGHKKEAERGLIGALGPGFSSELLLFS
CCHHHHHHHHHHHHHCCCCCHHHHHHEEHHHHCCCCHHHHHCCCEECCCCCCCCCEEEEE
WEKGA
ECCCC
>Mature Secondary Structure 
AFILSIGTSLPAYNVNQEKAAEFARYMFQHSFKDIDRLLSSFKNGQIHSRQFVKPIEWY
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KEGHSFEEKNQIYIEETLKHSRAAVRECLSHPEFFQEAIPYEKVEAVFFVSSTGLSTPSI
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHEEEEEEEECCCCCCCCH
EARLMNELPFSPYTKRIPIWGLGCAGGASGLARAAEYCKAYPEAFVLVISAELCSLTFQP
HHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHEEHEEEHHHHHEECCC
EDKTKSNLIGTSLFGDGIAAALLCGEKADRRVSKLKLAPKIMDAQSVLMKQSEDVMGWDF
CCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDQGFKVIFSRDIPTLVEKWLKTNVQIFLDKHKLSFHDISVFLAHPGGKKVIDAYIKSLG
CCCCCEEEEECCCHHHHHHHHHCCEEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHC
LSSEKLSSAQSILQKHGNMSSATILYVIKDHLQNGHKKEAERGLIGALGPGFSSELLLFS
CCHHHHHHHHHHHHHCCCCCHHHHHHEEHHHHCCCCHHHHHCCCEECCCCCCCCCEEEEE
WEKGA
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377