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The map label for this gene is ftsR

Identifier: 16078903

GI number: 16078903

Start: 2006541

End: 2007398

Strand: Reverse

Name: ftsR

Synonym: BSU18420

Alternate gene names: 16078903

Gene position: 2007398-2006541 (Counterclockwise)

Preceding gene: 255767433

Following gene: 16078901

Centisome position: 47.62

GC content: 44.41

Gene sequence:

>858_bases
GTGGAAAGCGGAGATTTAAAGATTTTTCAGGCTGTTGCTCGCGAAGGAAGCATAACGAAAGCAGCCCAAATGCTGAATTA
TGTTCAGTCGAATGTGACAGCCAGAGTGCATAACCTTGAGGAAGATTTGAATATCAGGCTTTTTCATCGAACGAATCGGG
GAATGAAGCTGACTGCTGCAGGAGAAAATCTTTTACAATATGCAGATCAAGTATTATCGCTGTTAGACCAAGCTGAAAAA
TCGACCCGAATGAGCAGGCAACCAAAAGGGCCTTTGCGGATCGGATCACTGGAAACAATGGCGGTAACGCATCTGCCTGA
GCATGCAGCATCCTTCCTCAGGCGTTTTCCTGAAGTGGATTTATCAGTGAACACAGCTGATACGCATCATTTGATTCAAC
AGGTTCTTGATCATAAAGTTGATGGCGCTTTTGTATATGGGCCGGTTGAACACGCTGCAGTTAGACAACTCCATGTCTCC
CATGATGAATTAGTTTTGATTTCATCACGAGAAGGGACGGCAGAAGACATGCTTCAGCAGCCGATGCTCTTTTTTGGGGC
TGGCTGTTCTCATCGTGACAGGGTCAAAAGATTACTAGAGGAAGCAGGCATACACAATCAAAAAATCATAGAGTTTGGCA
CATTGGAGGCTATTATAAAAGGTGTTTCCGCCGGGATGGGTACGGCGCTGCTCCCAAAGTCCGCTGTTGACGGCTCCGAG
CATCGTACAAATGTATGGATTCATCAGCTGCCACCATCATATCAAGACTTAGAGATCGTCTTTATATACAGGAAAGACTT
TTTTATTACGAGTGCGTTTCAGACATTTCTTGATGAGATAAACGAAATGAAAAGATGA

Upstream 100 bases:

>100_bases
TTCATATCTTTACATATTTTACATAGCGGTTTTCTTCGAGTAAAATGAACAAATATGATAGCCAATATCACTTTTCATCA
TAGCAAGCAGGTGAGAGCGC

Downstream 100 bases:

>100_bases
AGATAGACGTGCATTAGCAGAATAAAGACGTTTGTCAGTTTTTATTTTAAAGATCTGCATGAAAAAACTGTACTCATTTG
AAGCGAGTACAGTTTTTTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNIRLFHRTNRGMKLTAAGENLLQYADQVLSLLDQAEK
STRMSRQPKGPLRIGSLETMAVTHLPEHAASFLRRFPEVDLSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVS
HDELVLISSREGTAEDMLQQPMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAIIKGVSAGMGTALLPKSAVDGSE
HRTNVWIHQLPPSYQDLEIVFIYRKDFFITSAFQTFLDEINEMKR

Sequences:

>Translated_285_residues
MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNIRLFHRTNRGMKLTAAGENLLQYADQVLSLLDQAEK
STRMSRQPKGPLRIGSLETMAVTHLPEHAASFLRRFPEVDLSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVS
HDELVLISSREGTAEDMLQQPMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAIIKGVSAGMGTALLPKSAVDGSE
HRTNVWIHQLPPSYQDLEIVFIYRKDFFITSAFQTFLDEINEMKR
>Mature_285_residues
MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNIRLFHRTNRGMKLTAAGENLLQYADQVLSLLDQAEK
STRMSRQPKGPLRIGSLETMAVTHLPEHAASFLRRFPEVDLSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVS
HDELVLISSREGTAEDMLQQPMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAIIKGVSAGMGTALLPKSAVDGSE
HRTNVWIHQLPPSYQDLEIVFIYRKDFFITSAFQTFLDEINEMKR

Specific function: Regulates expression of the cell division protein ftsW, and is essential for cell viability during stationary phase

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787806, Length=271, Percent_Identity=31.3653136531365, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI87082132, Length=247, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=25.8741258741259, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788481, Length=239, Percent_Identity=27.6150627615063, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787879, Length=241, Percent_Identity=27.8008298755187, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=285, Percent_Identity=22.8070175438596, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788748, Length=286, Percent_Identity=24.4755244755245, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=25.3968253968254, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=24.8299319727891, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=26.1016949152542, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790262, Length=252, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=154, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=150, Percent_Identity=29.3333333333333, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789173, Length=142, Percent_Identity=30.9859154929577, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787530, Length=243, Percent_Identity=24.2798353909465, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787128, Length=145, Percent_Identity=31.7241379310345, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790208, Length=257, Percent_Identity=27.6264591439689, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87081904, Length=137, Percent_Identity=30.6569343065693, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YOFA_BACSU (O34685)

Other databases:

- EMBL:   AL009126
- PIR:   E69905
- RefSeq:   NP_389724.1
- ProteinModelPortal:   O34685
- SMR:   O34685
- EnsemblBacteria:   EBBACT00000000975
- GeneID:   940018
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU18420
- NMPDR:   fig|224308.1.peg.1846
- GenoList:   BSU18420
- GeneTree:   EBGT00070000031761
- HOGENOM:   HBG685425
- OMA:   EEMVIIA
- PhylomeDB:   O34685
- ProtClustDB:   CLSK887372
- BioCyc:   BSUB:BSU18420-MONOMER
- GO:   GO:0005737
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 32051; Mature: 32051

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNIRLFHRTNRGMKLTAA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEC
GENLLQYADQVLSLLDQAEKSTRMSRQPKGPLRIGSLETMAVTHLPEHAASFLRRFPEVD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHCHHHHHHHHHHCCCCC
LSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVSHDELVLISSREGTAEDMLQQ
EEECCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHC
PMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAIIKGVSAGMGTALLPKSAVDGSE
CHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCC
HRTNVWIHQLPPSYQDLEIVFIYRKDFFITSAFQTFLDEINEMKR
CCCEEEEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNIRLFHRTNRGMKLTAA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEC
GENLLQYADQVLSLLDQAEKSTRMSRQPKGPLRIGSLETMAVTHLPEHAASFLRRFPEVD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHCHHHHHHHHHHCCCCC
LSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVSHDELVLISSREGTAEDMLQQ
EEECCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHC
PMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAIIKGVSAGMGTALLPKSAVDGSE
CHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCC
HRTNVWIHQLPPSYQDLEIVFIYRKDFFITSAFQTFLDEINEMKR
CCCEEEEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377