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The map label for this gene is sirB

Identifier: 16078626

GI number: 16078626

Start: 1634837

End: 1635622

Strand: Direct

Name: sirB

Synonym: BSU15620

Alternate gene names: 16078626

Gene position: 1634837-1635622 (Clockwise)

Preceding gene: 16078625

Following gene: 16078627

Centisome position: 38.78

GC content: 44.15

Gene sequence:

>786_bases
ATGAAACAAGCAATTTTATATGTCGGCCACGGCAGCCGGGTCAAAAAAGCGCAGCAAGAAGCCGCAGCCTTTTTGGAAGG
ATGCAAGGCCCACATCTCTGTGCCAGTACAAGAAATCAGCTTTTTAGAGCTTCAGGAGCCGACAATTGAGACAGGATTTG
AAGCATGTGTGAAGCAAGGTGCCACTCATATCGCAGTGGTGCCTCTGCTTCTTTTAACAGCTGCGCATGCAAAACATGAT
ATTCCGGAAGAAATTGTCCGTGTTGCATCTCGATATCCATCAGTCCGTATTTCATACGGAAAGCCGATCGGGATTGACGA
AGAAGTAGTCAAGGCTGTATATCACCGAATGAAAGACATAGGTGTTCCGTATGAAAATGCCAGAGTGGTGCTCATCGGAA
GGGGAAGTTCAGATCCAGACGTCAAAAGAGACGTAACCGGAATTGCTAATCTTCTTCAGGAAATGGTTCCAGTGAAGGAA
GTCATTCCGTGCTTTTTGACAGCATGCGGCCCTAATTACAAAGAGGTTTTTTCAGAACTTGAAAAAGATGACGGCATAAC
AACCTTTATCGTTCCATATTTGCTTTTTACGGGTATGCTGATGAATGAAATCGAACGAGAGGTTCAGAAATTAAAAGCCC
ATAATCCGAACGTCTACCTCTCTTCCTATATCGGTTTTCATCCTCATGTGAAAAACGCATTTTTGAACCGTGTGAGAGAA
ACTGCGGCAAATTCTGAGGGACAATTTGATTTTGATGGAGGTTCATATGCTTCCGCTGCACATTAG

Upstream 100 bases:

>100_bases
CGAGTTTAATTGTCATTGGAAATGTTGTAAATTATCACTATAAGCTGGAATGGTTTGAATCTGAACTAAAAAAACAAGAT
TTAAGCGAGGCGTTGTAAAA

Downstream 100 bases:

>100_bases
CCTGGAAAAGAAGAAGGTTGTGATTGCGGGGGGCGGAAGCATCGCTCTCAGAAGGCTGAAAACGGTGATTTCTGAGGGAG
CTGATATAACGCTTGTCAGT

Product: sirohydrochlorin ferrochelatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLELQEPTIETGFEACVKQGATHIAVVPLLLLTAAHAKHD
IPEEIVRVASRYPSVRISYGKPIGIDEEVVKAVYHRMKDIGVPYENARVVLIGRGSSDPDVKRDVTGIANLLQEMVPVKE
VIPCFLTACGPNYKEVFSELEKDDGITTFIVPYLLFTGMLMNEIEREVQKLKAHNPNVYLSSYIGFHPHVKNAFLNRVRE
TAANSEGQFDFDGGSYASAAH

Sequences:

>Translated_261_residues
MKQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLELQEPTIETGFEACVKQGATHIAVVPLLLLTAAHAKHD
IPEEIVRVASRYPSVRISYGKPIGIDEEVVKAVYHRMKDIGVPYENARVVLIGRGSSDPDVKRDVTGIANLLQEMVPVKE
VIPCFLTACGPNYKEVFSELEKDDGITTFIVPYLLFTGMLMNEIEREVQKLKAHNPNVYLSSYIGFHPHVKNAFLNRVRE
TAANSEGQFDFDGGSYASAAH
>Mature_261_residues
MKQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLELQEPTIETGFEACVKQGATHIAVVPLLLLTAAHAKHD
IPEEIVRVASRYPSVRISYGKPIGIDEEVVKAVYHRMKDIGVPYENARVVLIGRGSSDPDVKRDVTGIANLLQEMVPVKE
VIPCFLTACGPNYKEVFSELEKDDGITTFIVPYLLFTGMLMNEIEREVQKLKAHNPNVYLSSYIGFHPHVKNAFLNRVRE
TAANSEGQFDFDGGSYASAAH

Specific function: Chelates iron to the siroheme precursor

COG id: COG2138

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiX family. SirB subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SIRB_BACSU (O34632)

Other databases:

- EMBL:   AJ000974
- EMBL:   AL009126
- PIR:   E69877
- RefSeq:   NP_389445.1
- ProteinModelPortal:   O34632
- SMR:   O34632
- EnsemblBacteria:   EBBACT00000001291
- GeneID:   936218
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU15620
- NMPDR:   fig|224308.1.peg.1564
- GenoList:   BSU15620
- GeneTree:   EBGT00050000002174
- HOGENOM:   HBG672675
- OMA:   DQYVSTY
- ProtClustDB:   CLSK887285
- BioCyc:   BSUB:BSU15620-MONOMER
- BRENDA:   4.99.1.4
- InterPro:   IPR002762

Pfam domain/function: PF01903 CbiX

EC number: =4.99.1.4

Molecular weight: Translated: 28835; Mature: 28835

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 76-76

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLELQEPTIETGFEACVKQG
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCC
ATHIAVVPLLLLTAAHAKHDIPEEIVRVASRYPSVRISYGKPIGIDEEVVKAVYHRMKDI
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHC
GVPYENARVVLIGRGSSDPDVKRDVTGIANLLQEMVPVKEVIPCFLTACGPNYKEVFSEL
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHH
EKDDGITTFIVPYLLFTGMLMNEIEREVQKLKAHNPNVYLSSYIGFHPHVKNAFLNRVRE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCHHHHHHHHHHHH
TAANSEGQFDFDGGSYASAAH
HHCCCCCCEECCCCCCCCCCC
>Mature Secondary Structure
MKQAILYVGHGSRVKKAQQEAAAFLEGCKAHISVPVQEISFLELQEPTIETGFEACVKQG
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCC
ATHIAVVPLLLLTAAHAKHDIPEEIVRVASRYPSVRISYGKPIGIDEEVVKAVYHRMKDI
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHC
GVPYENARVVLIGRGSSDPDVKRDVTGIANLLQEMVPVKEVIPCFLTACGPNYKEVFSEL
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHH
EKDDGITTFIVPYLLFTGMLMNEIEREVQKLKAHNPNVYLSSYIGFHPHVKNAFLNRVRE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCHHHHHHHHHHHH
TAANSEGQFDFDGGSYASAAH
HHCCCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377