| Definition | Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome. |
|---|---|
| Accession | NC_000964 |
| Length | 4,215,606 |
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The map label for this gene is ykvO
Identifier: 16078441
GI number: 16078441
Start: 1442872
End: 1443618
Strand: Direct
Name: ykvO
Synonym: BSU13770
Alternate gene names: 16078441
Gene position: 1442872-1443618 (Clockwise)
Preceding gene: 16078439
Following gene: 16078442
Centisome position: 34.23
GC content: 40.83
Gene sequence:
>747_bases ATGGGTAAATTTGAAGGTAAAATAGCGCTTGTAACGGGTGGAACAAGTGGGATTGGTCTTGCTACAGCACAAAAATTTGT AAACGAAGGTGCATATGTTTATATTACGGGACGTAGACAAAACGAACTTGATAAAGCTGTTAACCAAATTGGCAAGAACG TAACCGGTGTTCAAGGTGATATTTCTAAGCTTGAAGACTTAGACAAACTATATGACATTATAAAGCAGGAAAAAGGTAAG TTGGACATTCTTTTTGCTAATGCAGGCATCGGCAACTTCCTTCCATTAGGTGAAATTACTGAAGAGCAGGTTGATAGAAC GTTCGACATTAACGTTAAAGGAACCATCTTTACTGTTCAAAAAGCGTTATCACTATTCCCGGACAAAGTAGGTTCTATTA TTGTAACGGGCTCTACTGCTGGATCAATTGGCAACCCAGCGTTTAGTGTATATGGAGCATCTAAAGCAGCATTAAGAGCA CTAGTTCGCAACTGGATTCTTGACCTAAAAGGTACTGAAATCCGTGTAAATGTGGTTAGTCCAGGAGGTATTCTTACACC TGCCTACGATGAGCTTTTTGGTGATGCACTTGAAGAGGTACTGGAAAATAGCAGAAATACTGTTCCAGCTGGAAAAGTTG GGACACCTGAAGAAGTAGCAAACGCTGTATCTTTCCTTGCTTCAGACGAAAGCAGTTACTTGACGGGTGTTGAATTGTTC GTAGATGGCGGGCTAGCACAGGTATAA
Upstream 100 bases:
>100_bases ATAATGTGCTTACTGAAGGATACTATATCTTGTAAGTTGTTCTTCAAGTACTTAAAGGTACTAGACATAAAATAAAATTA ATTCTAAAGGAGTGTTAAGT
Downstream 100 bases:
>100_bases TTTCACTGCGCAGAGATTACAAATAGTCCCCAAAAAAGGTTAATGGGGATTTACTTGAAGAAGTCGTATAAAAAAGTCGT TTTCCTTAAAGGACAGGGAA
Product: oxidoreductase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 247
Protein sequence:
>248_residues MGKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGDISKLEDLDKLYDIIKQEKGK LDILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQKALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRA LVRNWILDLKGTEIRVNVVSPGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTPEEVANAVSFLASDESSYLTGVELF VDGGLAQV
Sequences:
>Translated_248_residues MGKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGDISKLEDLDKLYDIIKQEKGK LDILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQKALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRA LVRNWILDLKGTEIRVNVVSPGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTPEEVANAVSFLASDESSYLTGVELF VDGGLAQV >Mature_247_residues GKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGDISKLEDLDKLYDIIKQEKGKL DILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQKALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRAL VRNWILDLKGTEIRVNVVSPGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTPEEVANAVSFLASDESSYLTGVELFV DGGLAQV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family
Homologues:
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=35.8024691358025, Blast_Score=143, Evalue=2e-34, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=33.0645161290323, Blast_Score=124, Evalue=8e-29, Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=34.1463414634146, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=30.1587301587302, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=32.5, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=34.5549738219895, Blast_Score=104, Evalue=8e-23, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=34.2541436464088, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=31.9672131147541, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=30.46875, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=31.9838056680162, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=30.7086614173228, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI4503817, Length=229, Percent_Identity=27.0742358078603, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI223718074, Length=210, Percent_Identity=29.0476190476191, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=27.843137254902, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4503301, Length=249, Percent_Identity=28.5140562248996, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=26.8421052631579, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=31.9587628865979, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=35.6275303643725, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=31.496062992126, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=35.4838709677419, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=32.5301204819277, Blast_Score=107, Evalue=5e-25, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=28.9795918367347, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=32.9317269076305, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=32.4, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1787820, Length=224, Percent_Identity=31.25, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=29.3877551020408, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1786701, Length=204, Percent_Identity=31.3725490196078, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=28.6885245901639, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=28.8617886178862, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787545, Length=261, Percent_Identity=27.2030651340996, Blast_Score=68, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=35.9683794466403, Blast_Score=134, Evalue=4e-32, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=35.8490566037736, Blast_Score=134, Evalue=5e-32, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=36.6412213740458, Blast_Score=133, Evalue=7e-32, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=35.4961832061069, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=34.3511450381679, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=34.7014925373134, Blast_Score=124, Evalue=6e-29, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=34.3511450381679, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=32.6923076923077, Blast_Score=120, Evalue=8e-28, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=35.3383458646617, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=33.8645418326693, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=31.5573770491803, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=34.9624060150376, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=32.6923076923077, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=33.587786259542, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=34.3873517786561, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=32.520325203252, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=31.6793893129771, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=32.7137546468402, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=30.5454545454545, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=30.5660377358491, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=31.7460317460317, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=32.6612903225806, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=27.9693486590038, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=32, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=30.3643724696356, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=31.640625, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=30.4511278195489, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=28.6274509803922, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=28.7958115183246, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193207185, Length=149, Percent_Identity=35.5704697986577, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71997402, Length=238, Percent_Identity=28.1512605042017, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555612, Length=247, Percent_Identity=27.5303643724696, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17568967, Length=169, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=29.4736842105263, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322067, Length=188, Percent_Identity=32.4468085106383, Blast_Score=92, Evalue=8e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=27.9527559055118, Blast_Score=91, Evalue=2e-19, Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=33.8461538461538, Blast_Score=78, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6322227, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=35.5731225296443, Blast_Score=137, Evalue=5e-33, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=35.2226720647773, Blast_Score=130, Evalue=1e-30, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=33.9920948616601, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=30.8, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=33.4677419354839, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=33.9920948616601, Blast_Score=103, Evalue=7e-23, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=30, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=29.6747967479675, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24663911, Length=200, Percent_Identity=26.5, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI281364494, Length=206, Percent_Identity=27.6699029126214, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=28.1746031746032, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24648944, Length=200, Percent_Identity=33.5, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007238, Length=197, Percent_Identity=27.9187817258883, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI281364892, Length=162, Percent_Identity=32.0987654320988, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI28571387, Length=205, Percent_Identity=27.3170731707317, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI116007234, Length=197, Percent_Identity=26.9035532994924, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24640492, Length=180, Percent_Identity=27.2222222222222, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24581726, Length=189, Percent_Identity=29.1005291005291, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24641232, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI161076371, Length=205, Percent_Identity=28.2926829268293, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): YKVO_BACSU (O31680)
Other databases:
- EMBL: AL009126 - PIR: F69868 - RefSeq: NP_389260.1 - HSSP: Q9BPX1 - ProteinModelPortal: O31680 - SMR: O31680 - EnsemblBacteria: EBBACT00000000816 - GeneID: 939276 - GenomeReviews: AL009126_GR - KEGG: bsu:BSU13770 - NMPDR: fig|224308.1.peg.1379 - GenoList: BSU13770 - GeneTree: EBGT00070000031724 - HOGENOM: HBG750976 - OMA: TPAYDEL - PhylomeDB: O31680 - ProtClustDB: CLSK887201 - BioCyc: BSUB:BSU13770-MONOMER - GO: GO:0005488 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - Gene3D: G3DSA:3.40.50.720 - PANTHER: PTHR19410 - PRINTS: PR00081
Pfam domain/function: PF00106 adh_short
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26245; Mature: 26114
Theoretical pI: Translated: 4.48; Mature: 4.48
Prosite motif: PS00061 ADH_SHORT
Important sites: ACT_SITE 151-151 BINDING 138-138
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 0.4 %Met (Translated Protein) 0.4 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 0.0 %Met (Mature Protein) 0.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGD CCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCC ISKLEDLDKLYDIIKQEKGKLDILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQ HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHH KALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRALVRNWILDLKGTEIRVNVVS HHHHHCCHHHCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEEC PGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTPEEVANAVSFLASDESSYLTGVELF CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEE VDGGLAQV ECCCCCCC >Mature Secondary Structure GKFEGKIALVTGGTSGIGLATAQKFVNEGAYVYITGRRQNELDKAVNQIGKNVTGVQGD CCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCC ISKLEDLDKLYDIIKQEKGKLDILFANAGIGNFLPLGEITEEQVDRTFDINVKGTIFTVQ HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHH KALSLFPDKVGSIIVTGSTAGSIGNPAFSVYGASKAALRALVRNWILDLKGTEIRVNVVS HHHHHCCHHHCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEEC PGGILTPAYDELFGDALEEVLENSRNTVPAGKVGTPEEVANAVSFLASDESSYLTGVELF CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEE VDGGLAQV ECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377