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The map label for this gene is ykvM

Identifier: 16078439

GI number: 16078439

Start: 1441291

End: 1441788

Strand: Direct

Name: ykvM

Synonym: BSU13750

Alternate gene names: 16078439

Gene position: 1441291-1441788 (Clockwise)

Preceding gene: 16078438

Following gene: 16078441

Centisome position: 34.19

GC content: 40.16

Gene sequence:

>498_bases
ATGACGACAAGAAAAGAATCAGAATTAGAAGGTGTAACATTGCTAGGCAATCAAGGTACAAATTATTTGTTCGAATATGC
ACCGGACGTGCTGGAATCCTTCCCTAATAAACATGTAAACCGTGATTACTTTGTAAAATTCAATTGCCCGGAATTCACAT
CTTTATGTCCTAAAACAGGCCAGCCTGACTTTGCGACAATCTACATCAGCTACATTCCTGATGAAAAAATGGTTGAAAGC
AAATCATTAAAGCTGTATCTATTCAGCTTCAGAAACCATGGTGACTTCCACGAGGACTGCATGAATATCATCATGAACGA
CTTGATTGAATTAATGGACCCGCGCTACATTGAAGTATGGGGCAAATTCACGCCAAGAGGCGGAATTTCCATTGATCCGT
ACACAAACTACGGAAAGCCTGGCACGAAGTATGAGAAAATGGCCGAATACCGTATGATGAACCATGATTTGTATCCGGAG
ACAATTGATAATCGTTAA

Upstream 100 bases:

>100_bases
TAGCTGTCGATGCGGAGCTGAATCTCGTCAGAGTGCTCCCGCAGCTGCACACCCTGTTATGGGGCAACAAACGCGGAGTA
TAATAGAAAGGAAGATGAAC

Downstream 100 bases:

>100_bases
TTATTCCGTTGTGTGATACGGAGTGTAAAAGGAAGTGGAGTCACAGTAAAATCCGAACATTCAGCGTTAATTTTCAGCGG
AAATGTGACCTGGTCACAGC

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTTRKESELEGVTLLGNQGTNYLFEYAPDVLESFPNKHVNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDEKMVES
KSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPE
TIDNR

Sequences:

>Translated_165_residues
MTTRKESELEGVTLLGNQGTNYLFEYAPDVLESFPNKHVNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDEKMVES
KSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPE
TIDNR
>Mature_164_residues
TTRKESELEGVTLLGNQGTNYLFEYAPDVLESFPNKHVNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDEKMVESK
SLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPET
IDNR

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789158, Length=83, Percent_Identity=37.3493975903614, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 19375; Mature: 19244

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRKESELEGVTLLGNQGTNYLFEYAPDVLESFPNKHVNRDYFVKFNCPEFTSLCPKTG
CCCCCCCCCCCEEEECCCCCCHHHHHCHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCCC
QPDFATIYISYIPDEKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVW
CCCEEEEEEEECCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
GKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPETIDNR
ECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TTRKESELEGVTLLGNQGTNYLFEYAPDVLESFPNKHVNRDYFVKFNCPEFTSLCPKTG
CCCCCCCCCCEEEECCCCCCHHHHHCHHHHHHCCCCCCCCEEEEEECCCHHHHCCCCCC
QPDFATIYISYIPDEKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVW
CCCEEEEEEEECCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
GKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPETIDNR
ECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA