| Definition | Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome. |
|---|---|
| Accession | NC_000964 |
| Length | 4,215,606 |
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The map label for this gene is yjdA
Identifier: 16078263
GI number: 16078263
Start: 1268829
End: 1269584
Strand: Direct
Name: yjdA
Synonym: BSU11980
Alternate gene names: 16078263
Gene position: 1268829-1269584 (Clockwise)
Preceding gene: 16078262
Following gene: 255767270
Centisome position: 30.1
GC content: 38.62
Gene sequence:
>756_bases ATGAGTCATTCTCAAGAAAAAATTGCACTAATTACAGGAGCAAGCAGTCAAGGGGATATTGGTACGGCTATTTGTCGTAA GTTAGCCTCACAGGGTATACATATCTTCTTTACTCACTGGAATTCTGATACGGCCTGGATAGAAGAATTTCAACAAGAAA TTTTACGTATGGGTGTCCGCTGTGAGGCAATGAAAATTGATTTATCAGATGCACATGCTGCATTCACAATACATGAAAAA ATTTCAGATAAATTAGGATATCCTTCCATCCTTATTAATAATGCAGCTCATTCCGCAAGTGATAATTATGTATCGTTAGA TGCTAAATCACTTGATGAGCATTATGCGGTTAATATGAGATCGAATTTTCTTCTTTGTGTTGAATTCGCCCGTCGGTTTA AAAAATCTAATTTAATATCAGGAAGAATCATCAATATGACATCAGGGCAGGATTTAGGTCCTTTGCCTGGGGAGTTAGCG TATGCAGCAACTAAAGGAGCTATTTCTGCATTTACTAGGTCGTTATCACAAGAACTTGCACCATTGGGCATCACTGTTAA CGCCGTAAACCCAGGTCCAACAGATTCTACATGGATGACAGATGAAATAAGAAATTTTCTTTCACCTAAATTTCCAATGG GGCGTATTGGCACACCAGATGATGCAGCACGAATGATTGCCTTTCTTGCAAGTGATGAGGCTGAATGGATAACTGGACAA ATTATTCATTCAGAAGGTGGATTTATTCGGGGCTAA
Upstream 100 bases:
>100_bases GTATTCAAAGTCAGCTCTGTTTGATTTAATGGATTATATTATTTGGATAGCTTGTTACCATCATAATGGAGATACTCCTT ATAAATTGGAGGTTAAAATA
Downstream 100 bases:
>100_bases GCTAATGAAACACGGTATACACCAATGTATGATGTATTCCCAAAACTAAATCTAAACTTGAAGCGAAAATAAGGTCCCTT CTCTTTTTAGAGGGGGACCT
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MSHSQEKIALITGASSQGDIGTAICRKLASQGIHIFFTHWNSDTAWIEEFQQEILRMGVRCEAMKIDLSDAHAAFTIHEK ISDKLGYPSILINNAAHSASDNYVSLDAKSLDEHYAVNMRSNFLLCVEFARRFKKSNLISGRIINMTSGQDLGPLPGELA YAATKGAISAFTRSLSQELAPLGITVNAVNPGPTDSTWMTDEIRNFLSPKFPMGRIGTPDDAARMIAFLASDEAEWITGQ IIHSEGGFIRG
Sequences:
>Translated_251_residues MSHSQEKIALITGASSQGDIGTAICRKLASQGIHIFFTHWNSDTAWIEEFQQEILRMGVRCEAMKIDLSDAHAAFTIHEK ISDKLGYPSILINNAAHSASDNYVSLDAKSLDEHYAVNMRSNFLLCVEFARRFKKSNLISGRIINMTSGQDLGPLPGELA YAATKGAISAFTRSLSQELAPLGITVNAVNPGPTDSTWMTDEIRNFLSPKFPMGRIGTPDDAARMIAFLASDEAEWITGQ IIHSEGGFIRG >Mature_250_residues SHSQEKIALITGASSQGDIGTAICRKLASQGIHIFFTHWNSDTAWIEEFQQEILRMGVRCEAMKIDLSDAHAAFTIHEKI SDKLGYPSILINNAAHSASDNYVSLDAKSLDEHYAVNMRSNFLLCVEFARRFKKSNLISGRIINMTSGQDLGPLPGELAY AATKGAISAFTRSLSQELAPLGITVNAVNPGPTDSTWMTDEIRNFLSPKFPMGRIGTPDDAARMIAFLASDEAEWITGQI IHSEGGFIRG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family
Homologues:
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=29.5719844357977, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=29.3650793650794, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI7705925, Length=192, Percent_Identity=27.6041666666667, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=25.1028806584362, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=25.4980079681275, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI109715829, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=27.2189349112426, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI4503301, Length=202, Percent_Identity=23.7623762376238, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=33.6, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=31.7073170731707, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=31.1475409836066, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=32.0754716981132, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.4584980237154, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=27.9527559055118, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=27.5303643724696, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1786812, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=27.5590551181102, Blast_Score=72, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=30.2238805970149, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.968253968254, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=29.9625468164794, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=29.4776119402985, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=30.6818181818182, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=30.2238805970149, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=27.9527559055118, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=29.3233082706767, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=28.7449392712551, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=28.8, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=28.996282527881, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=29.3233082706767, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=27.3809523809524, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=30, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=28.3088235294118, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=30.4511278195489, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=29.9212598425197, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=30.3703703703704, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17561272, Length=203, Percent_Identity=26.1083743842365, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=29.0196078431373, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=25.4980079681275, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=28.4644194756554, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=26.4367816091954, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=30.7692307692308, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=30.6772908366534, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=29.9212598425197, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=30.7392996108949, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=28.6852589641434, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=29.4573643410853, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.1255060728745, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24644337, Length=229, Percent_Identity=27.9475982532751, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=32, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=29.2079207920792, Blast_Score=67, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): YJDA_BACSU (O31642)
Other databases:
- EMBL: AL009126 - PIR: D69848 - RefSeq: NP_389080.1 - HSSP: Q16698 - ProteinModelPortal: O31642 - SMR: O31642 - EnsemblBacteria: EBBACT00000001952 - GeneID: 939818 - GenomeReviews: AL009126_GR - KEGG: bsu:BSU11980 - NMPDR: fig|224308.1.peg.1199 - GenoList: BSU11980 - GeneTree: EBGT00070000031994 - HOGENOM: HBG750976 - OMA: TAICRKL - ProtClustDB: PRK12748 - BioCyc: BSUB:BSU11980-MONOMER - GO: GO:0005488 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 - Gene3D: G3DSA:3.40.50.720 - PANTHER: PTHR19410 - PRINTS: PR00081 - PRINTS: PR00080
Pfam domain/function: PF00106 adh_short
EC number: 1.1.1.100
Molecular weight: Translated: 27449; Mature: 27318
Theoretical pI: Translated: 6.08; Mature: 6.08
Prosite motif: PS00061 ADH_SHORT
Important sites: ACT_SITE 161-161 BINDING 148-148
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSHSQEKIALITGASSQGDIGTAICRKLASQGIHIFFTHWNSDTAWIEEFQQEILRMGVR CCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHCCC CEAMKIDLSDAHAAFTIHEKISDKLGYPSILINNAAHSASDNYVSLDAKSLDEHYAVNMR EEEEEEECCCCCEEEEEHHHHHHHCCCCEEEEECCCCCCCCCEEEEEHHHCCCCEEEECC SNFLLCVEFARRFKKSNLISGRIINMTSGQDLGPLPGELAYAATKGAISAFTRSLSQELA CCEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC PLGITVNAVNPGPTDSTWMTDEIRNFLSPKFPMGRIGTPDDAARMIAFLASDEAEWITGQ CCCEEEEECCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEE IIHSEGGFIRG EEECCCCCCCC >Mature Secondary Structure SHSQEKIALITGASSQGDIGTAICRKLASQGIHIFFTHWNSDTAWIEEFQQEILRMGVR CCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHCCC CEAMKIDLSDAHAAFTIHEKISDKLGYPSILINNAAHSASDNYVSLDAKSLDEHYAVNMR EEEEEEECCCCCEEEEEHHHHHHHCCCCEEEEECCCCCCCCCEEEEEHHHCCCCEEEECC SNFLLCVEFARRFKKSNLISGRIINMTSGQDLGPLPGELAYAATKGAISAFTRSLSQELA CCEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC PLGITVNAVNPGPTDSTWMTDEIRNFLSPKFPMGRIGTPDDAARMIAFLASDEAEWITGQ CCCEEEEECCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEE IIHSEGGFIRG EEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377