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The map label for this gene is manR

Identifier: 255767270

GI number: 255767270

Start: 1270631

End: 1272577

Strand: Direct

Name: manR

Synonym: BSU12000

Alternate gene names: 255767270

Gene position: 1270631-1272577 (Clockwise)

Preceding gene: 16078263

Following gene: 255767271

Centisome position: 30.14

GC content: 40.37

Gene sequence:

>1947_bases
ATGGAATACATAAATACAAGACAAAAAGAGATTTTGTATCTGTTGTTATCTGAACCTGATGACTATTTAGTTGTGCAAGA
TTTCGCAGATAGGGTACAGTGTTCTGAAAAAACAATCCGGAATGATTTGAAAGTGATCGAGGATTATCTCAATGAGCATT
CTCATGCACAGCTTATTCGAAAACCAGGGTTGGGCGTTTATTTACATATAGAAGAACAGGAAAGGACCTGGCTAAGCCAA
CAATTACATACTGAACATTTTTCTTCTAGGCAGCGGAGCGATAAGGAAAGAATGCTGCACATTGCTTATGACTTATTAAT
GAATCCGAAGCCTGTTTCCGCAAAAGACATTGCCGCTCGGCATTTTGTCAATCGATCTTCCATTAAAAAGGATTTATACG
CAGTAGAAGAGTGGCTGAAGCGTTTTGATCTCACACTGGTTTCTAGGCAGCGGCTTGGATTAAAGGTTGAAGGGAACGAA
AGAAATAAAAGAAAGGCATTGGCAAGAATATCTGATTTGATTCACAATACAGCGTTTACCAGCCAATTTATTAAAAGTAA
GTTTTTACATTATGAAGTAGACTTTGTGACGAAAGAAATCAAATCACTACAAAAAAAGCATTCCCTCTATTTCACAGACG
AAACGTTTGAAAGTTTGTTGCTGCATACATTGTTAATGGTCCGCCGCATCAAAATGAAGCAGCCGATTTCATTGTCCCCA
AAAGAAATGGCGGCAGTAAAAAAGAAGAAAGAATATCAATGGACATTTGCTTGTTTACAGCGGCTTGAACCGGTTTTTGC
AATTCGCTTCCCTGAAGAAGAAGCCGTGTACTTAACATTACATATATTGGGCGGTAAGGTTCGTTATCCATTGCAGACAG
AAGAGAACCTTGAAAATGCTGTGCTTCCTAAGGTTGTAGGGCATTTAATCAATCGTGTTTCAGAGCTGAAAATGATGGAT
TTTCACAAGGATCAGGATTTGATCAATGGTTTGAACATTCATCTCAATACTGTGCTACAACGGCTGAGCTACGATCTTTC
TGTAGCAAATCCTATGCTCAATGACATCAAAAAGATGTACCCTTATTTGTTCCACCTCATCATTGATGTTTTGGAAGACA
TCAATCAAACTTTTGATCTTCATATTCCTGAGGAAGAGGCAGCATATTTGACATTGCATTTTCAGGCAGCGATCGAACGG
ATGCAGGGCAGCAGCGAGACACATAAAAAGGCGGTTATCGTCTGCCACATGGGGATTGGGATGTCACAATTGCTGCGGAC
AAAAATTGAACGGAAATATCACCAAATCGCTGTAATGGCTTGTATTGCAAAGGCCGATTTAAAGGATTATATCAAAAAGC
ATGAGGATATTGATCTTGTCATATCCACCATTGCGCTGGAGAATATAACGGTTCCCCATATTGTTGTGTCTCCGCTTTTA
GAGCCTGGCGAAGAGAAGAAATTAAGTGCGTTTATACGTCAGCTGGGCGAATCACACCGCCAAAAACAAAAAACGTTTCA
GATGCTGAACAATACGACTCCTTTTTTGGTTTTTTTGCAGCAGGAGGCGGAGCATCGCTACAAGTTAATCGAACAGCTGG
CGACAGCTTTGTTTGAGAAAGGCTATGTTGATAAGGACTATGCGGTTCATGCGGTGATGAGGGAAAAAATGTCGGCTACA
AATATTGGGTCAGGCATTGCCATTCCTCATGCAAACGCTAAATTTATTAAACAATCAGCAATCGCGATTGCCACATTAAA
GGAGCCGCTTGAATGGGGAAATGAAAAAGTTTCGCTCGTTTTTATGCTGGCTGTCAAACACGAGGATCAAACTATGACAA
AGCAGCTGTTTAGCGAGCTTTCATATCTTAGCGAGCAGCCGGCCTTCGTCCAGAAGCTGACGAAAGAAACCAATGTCATG
ACATTTTTATCTCATTTGGATTATTAA

Upstream 100 bases:

>100_bases
TCTCTATGATTTTGTTTTATAATGTAAACGGTTTCTTATATAGTATACTTATACTATCAATTTGCTCAAGTAGATACTGA
CAGGAAGGATAGAAAAACAG

Downstream 100 bases:

>100_bases
AAGCAGGGATTATTCCTTGCTTTTTTTGTTATAGGGAAAAATGCCTTTATTACCGGAACCTATGGTAAAAAAAGCGATTT
TAATGAGCTGATTTCGGTAT

Product: transcriptional antiterminator

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MEYINTRQKEILYLLLSEPDDYLVVQDFADRVQCSEKTIRNDLKVIEDYLNEHSHAQLIRKPGLGVYLHIEEQERTWLSQ
QLHTEHFSSRQRSDKERMLHIAYDLLMNPKPVSAKDIAARHFVNRSSIKKDLYAVEEWLKRFDLTLVSRQRLGLKVEGNE
RNKRKALARISDLIHNTAFTSQFIKSKFLHYEVDFVTKEIKSLQKKHSLYFTDETFESLLLHTLLMVRRIKMKQPISLSP
KEMAAVKKKKEYQWTFACLQRLEPVFAIRFPEEEAVYLTLHILGGKVRYPLQTEENLENAVLPKVVGHLINRVSELKMMD
FHKDQDLINGLNIHLNTVLQRLSYDLSVANPMLNDIKKMYPYLFHLIIDVLEDINQTFDLHIPEEEAAYLTLHFQAAIER
MQGSSETHKKAVIVCHMGIGMSQLLRTKIERKYHQIAVMACIAKADLKDYIKKHEDIDLVISTIALENITVPHIVVSPLL
EPGEEKKLSAFIRQLGESHRQKQKTFQMLNNTTPFLVFLQQEAEHRYKLIEQLATALFEKGYVDKDYAVHAVMREKMSAT
NIGSGIAIPHANAKFIKQSAIAIATLKEPLEWGNEKVSLVFMLAVKHEDQTMTKQLFSELSYLSEQPAFVQKLTKETNVM
TFLSHLDY

Sequences:

>Translated_648_residues
MEYINTRQKEILYLLLSEPDDYLVVQDFADRVQCSEKTIRNDLKVIEDYLNEHSHAQLIRKPGLGVYLHIEEQERTWLSQ
QLHTEHFSSRQRSDKERMLHIAYDLLMNPKPVSAKDIAARHFVNRSSIKKDLYAVEEWLKRFDLTLVSRQRLGLKVEGNE
RNKRKALARISDLIHNTAFTSQFIKSKFLHYEVDFVTKEIKSLQKKHSLYFTDETFESLLLHTLLMVRRIKMKQPISLSP
KEMAAVKKKKEYQWTFACLQRLEPVFAIRFPEEEAVYLTLHILGGKVRYPLQTEENLENAVLPKVVGHLINRVSELKMMD
FHKDQDLINGLNIHLNTVLQRLSYDLSVANPMLNDIKKMYPYLFHLIIDVLEDINQTFDLHIPEEEAAYLTLHFQAAIER
MQGSSETHKKAVIVCHMGIGMSQLLRTKIERKYHQIAVMACIAKADLKDYIKKHEDIDLVISTIALENITVPHIVVSPLL
EPGEEKKLSAFIRQLGESHRQKQKTFQMLNNTTPFLVFLQQEAEHRYKLIEQLATALFEKGYVDKDYAVHAVMREKMSAT
NIGSGIAIPHANAKFIKQSAIAIATLKEPLEWGNEKVSLVFMLAVKHEDQTMTKQLFSELSYLSEQPAFVQKLTKETNVM
TFLSHLDY
>Mature_648_residues
MEYINTRQKEILYLLLSEPDDYLVVQDFADRVQCSEKTIRNDLKVIEDYLNEHSHAQLIRKPGLGVYLHIEEQERTWLSQ
QLHTEHFSSRQRSDKERMLHIAYDLLMNPKPVSAKDIAARHFVNRSSIKKDLYAVEEWLKRFDLTLVSRQRLGLKVEGNE
RNKRKALARISDLIHNTAFTSQFIKSKFLHYEVDFVTKEIKSLQKKHSLYFTDETFESLLLHTLLMVRRIKMKQPISLSP
KEMAAVKKKKEYQWTFACLQRLEPVFAIRFPEEEAVYLTLHILGGKVRYPLQTEENLENAVLPKVVGHLINRVSELKMMD
FHKDQDLINGLNIHLNTVLQRLSYDLSVANPMLNDIKKMYPYLFHLIIDVLEDINQTFDLHIPEEEAAYLTLHFQAAIER
MQGSSETHKKAVIVCHMGIGMSQLLRTKIERKYHQIAVMACIAKADLKDYIKKHEDIDLVISTIALENITVPHIVVSPLL
EPGEEKKLSAFIRQLGESHRQKQKTFQMLNNTTPFLVFLQQEAEHRYKLIEQLATALFEKGYVDKDYAVHAVMREKMSAT
NIGSGIAIPHANAKFIKQSAIAIATLKEPLEWGNEKVSLVFMLAVKHEDQTMTKQLFSELSYLSEQPAFVQKLTKETNVM
TFLSHLDY

Specific function: May regulate the expression of the mannose operon

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MANR_BACSU (O31644)

Other databases:

- EMBL:   AL009126
- RefSeq:   NP_389082.2
- ProteinModelPortal:   O31644
- EnsemblBacteria:   EBBACT00000000740
- GeneID:   939394
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU12000
- NMPDR:   fig|224308.1.peg.1201
- GenoList:   BSU12000
- GeneTree:   EBGT00070000032076
- HOGENOM:   HBG338196
- ProtClustDB:   CLSK887087
- BioCyc:   BSUB:BSU12000-MONOMER
- GO:   GO:0006350
- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.1790.10
- Gene3D:   G3DSA:3.40.930.10
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; SSF63520 PRD; SSF55804 PTrfase/Anion_transptr

EC number: =2.7.1.69

Molecular weight: Translated: 75352; Mature: 75352

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00654 PRD_1; PS51372 PRD_2; PS51094 PTS_EIIA_TYPE_2; PS00372 PTS_EIIA_TYPE_2_HIS; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYINTRQKEILYLLLSEPDDYLVVQDFADRVQCSEKTIRNDLKVIEDYLNEHSHAQLIR
CCCCCCCHHHEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KPGLGVYLHIEEQERTWLSQQLHTEHFSSRQRSDKERMLHIAYDLLMNPKPVSAKDIAAR
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
HFVNRSSIKKDLYAVEEWLKRFDLTLVSRQRLGLKVEGNERNKRKALARISDLIHNTAFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHH
SQFIKSKFLHYEVDFVTKEIKSLQKKHSLYFTDETFESLLLHTLLMVRRIKMKQPISLSP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KEMAAVKKKKEYQWTFACLQRLEPVFAIRFPEEEAVYLTLHILGGKVRYPLQTEENLENA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCEEECCCCCHHCHHHH
VLPKVVGHLINRVSELKMMDFHKDQDLINGLNIHLNTVLQRLSYDLSVANPMLNDIKKMY
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHH
PYLFHLIIDVLEDINQTFDLHIPEEEAAYLTLHFQAAIERMQGSSETHKKAVIVCHMGIG
HHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCEEEEEECCCC
MSQLLRTKIERKYHQIAVMACIAKADLKDYIKKHEDIDLVISTIALENITVPHIVVSPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHC
EPGEEKKLSAFIRQLGESHRQKQKTFQMLNNTTPFLVFLQQEAEHRYKLIEQLATALFEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHC
GYVDKDYAVHAVMREKMSATNIGSGIAIPHANAKFIKQSAIAIATLKEPLEWGNEKVSLV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
FMLAVKHEDQTMTKQLFSELSYLSEQPAFVQKLTKETNVMTFLSHLDY
EEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYINTRQKEILYLLLSEPDDYLVVQDFADRVQCSEKTIRNDLKVIEDYLNEHSHAQLIR
CCCCCCCHHHEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KPGLGVYLHIEEQERTWLSQQLHTEHFSSRQRSDKERMLHIAYDLLMNPKPVSAKDIAAR
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
HFVNRSSIKKDLYAVEEWLKRFDLTLVSRQRLGLKVEGNERNKRKALARISDLIHNTAFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHH
SQFIKSKFLHYEVDFVTKEIKSLQKKHSLYFTDETFESLLLHTLLMVRRIKMKQPISLSP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KEMAAVKKKKEYQWTFACLQRLEPVFAIRFPEEEAVYLTLHILGGKVRYPLQTEENLENA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCEEECCCCCHHCHHHH
VLPKVVGHLINRVSELKMMDFHKDQDLINGLNIHLNTVLQRLSYDLSVANPMLNDIKKMY
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHH
PYLFHLIIDVLEDINQTFDLHIPEEEAAYLTLHFQAAIERMQGSSETHKKAVIVCHMGIG
HHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCEEEEEECCCC
MSQLLRTKIERKYHQIAVMACIAKADLKDYIKKHEDIDLVISTIALENITVPHIVVSPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHC
EPGEEKKLSAFIRQLGESHRQKQKTFQMLNNTTPFLVFLQQEAEHRYKLIEQLATALFEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHC
GYVDKDYAVHAVMREKMSATNIGSGIAIPHANAKFIKQSAIAIATLKEPLEWGNEKVSLV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
FMLAVKHEDQTMTKQLFSELSYLSEQPAFVQKLTKETNVMTFLSHLDY
EEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377