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The map label for this gene is nsrR

Identifier: 16078003

GI number: 16078003

Start: 1013411

End: 1013851

Strand: Reverse

Name: nsrR

Synonym: BSU09380

Alternate gene names: 16078003

Gene position: 1013851-1013411 (Counterclockwise)

Preceding gene: 16078004

Following gene: 255767220

Centisome position: 24.05

GC content: 41.27

Gene sequence:

>441_bases
ATGAAGTTAACCAATTATACAGATTATTCATTAAGAGTGTTGATTTTTCTGGCTGCAGAGCGTCCCGGAGAACTTTCAAA
TATAAAACAGATTGCCGAAACGTATTCTATTTCAAAAAATCATCTCATGAAAGTCATATACAGGCTCGGCCAGCTCGGCT
ACGTAGAAACGATACGCGGACGGGGCGGCGGCATACGATTAGGCATGGACCCTGAAGACATCAACATCGGTGAGGTTGTC
AGAAAAACGGAGGACGATTTTAATATTGTTGAATGTTTTGATGCGAACAAGAATCTCTGTGTTATTTCCCCGGTTTGCGG
CTTAAAACATGTGCTGAATGAAGCGCTTTTAGCCTACCTCGCAGTTTTAGACAAATACACACTGCGCGACCTCGTCAAAA
ACAAAGAAGATATCATGAAGCTTTTAAAAATGAAGGAATAG

Upstream 100 bases:

>100_bases
AACATGCACCCAGCTGGGTGCATGTTTTTTAATTCCTTTTTTTTCATTTTTCAATCGATTATGATAAGATATAGAAAATG
TCTTATTCTGAGGTCTTATT

Downstream 100 bases:

>100_bases
ATTAAGATTCCTTCTTTTTTTATGCCCTTTTTCCCCCTTATTGTTAAGATAATTTGGCTATTTTTATAAAAAGGCAAAAC
GATGAGACAAATGTGCCGAT

Product: NO-dependent activator of the ResDE regulon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKLTNYTDYSLRVLIFLAAERPGELSNIKQIAETYSISKNHLMKVIYRLGQLGYVETIRGRGGGIRLGMDPEDINIGEVV
RKTEDDFNIVECFDANKNLCVISPVCGLKHVLNEALLAYLAVLDKYTLRDLVKNKEDIMKLLKMKE

Sequences:

>Translated_146_residues
MKLTNYTDYSLRVLIFLAAERPGELSNIKQIAETYSISKNHLMKVIYRLGQLGYVETIRGRGGGIRLGMDPEDINIGEVV
RKTEDDFNIVECFDANKNLCVISPVCGLKHVLNEALLAYLAVLDKYTLRDLVKNKEDIMKLLKMKE
>Mature_146_residues
MKLTNYTDYSLRVLIFLAAERPGELSNIKQIAETYSISKNHLMKVIYRLGQLGYVETIRGRGGGIRLGMDPEDINIGEVV
RKTEDDFNIVECFDANKNLCVISPVCGLKHVLNEALLAYLAVLDKYTLRDLVKNKEDIMKLLKMKE

Specific function: Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790621, Length=142, Percent_Identity=42.2535211267606, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NSRR_BACSU (O07573)

Other databases:

- EMBL:   Y14082
- EMBL:   Y14079
- EMBL:   AL009126
- PIR:   C69825
- RefSeq:   NP_388819.1
- ProteinModelPortal:   O07573
- SMR:   O07573
- EnsemblBacteria:   EBBACT00000000882
- GeneID:   939744
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU09380
- NMPDR:   fig|224308.1.peg.938
- GenoList:   BSU09380
- GeneTree:   EBGT00070000032063
- HOGENOM:   HBG725923
- OMA:   ITNSCQF
- PhylomeDB:   O07573
- ProtClustDB:   CLSK886954
- BioCyc:   BSUB:BSU09380-MONOMER
- GO:   GO:0006350
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 16610; Mature: 16610

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTNYTDYSLRVLIFLAAERPGELSNIKQIAETYSISKNHLMKVIYRLGQLGYVETIRG
CCCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCC
RGGGIRLGMDPEDINIGEVVRKTEDDFNIVECFDANKNLCVISPVCGLKHVLNEALLAYL
CCCEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHH
AVLDKYTLRDLVKNKEDIMKLLKMKE
HHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MKLTNYTDYSLRVLIFLAAERPGELSNIKQIAETYSISKNHLMKVIYRLGQLGYVETIRG
CCCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCC
RGGGIRLGMDPEDINIGEVVRKTEDDFNIVECFDANKNLCVISPVCGLKHVLNEALLAYL
CCCEEEECCCCCCCCHHHHHHHCCCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHHHH
AVLDKYTLRDLVKNKEDIMKLLKMKE
HHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377