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The map label for this gene is yfkE

Identifier: 16077859

GI number: 16077859

Start: 865205

End: 866260

Strand: Direct

Name: yfkE

Synonym: BSU07920

Alternate gene names: 16077859

Gene position: 865205-866260 (Clockwise)

Preceding gene: 16077857

Following gene: 16077860

Centisome position: 20.52

GC content: 47.92

Gene sequence:

>1056_bases
ATGAATCGTATCTTTTTTATTTTAGTGGCGGCCGGTGTTCCGCTTTCTGTGATTGGCAGTTTGATGCATTGGCCTTCCGC
GGTTCTATTTGCAGTTTATTGCGTGACGATTATCGCGCTTGCAAGCTATATGGGGAGGGCGACAGAATCACTGTCCATCA
TTGCAGGACCGCGTATCGGCGGTTTGTTGAATGCAACCTTCGGGAATGCGGTGGAGCTGATTATTTCCCTTTTTGCATTA
AAAGAAGGCCTGACAGGAATCGTGCTTGCCTCTTTAACCGGTTCAGTGCTGGGGAACCTGTTGCTGGTAGCGGGCCTATC
GTTTTTTGTCGGCGGTTTAAAATATAAGCGGCAGGAATTTAATATCCATGATGCCCGCCATAACTCCGGGCTTCTGATTT
TTGCCATCATTGTCGCCTTTGTGATTCCGGAGGTATTCTCTGTTGGTATGGGAAACGCCAGCAAGCTCAATTTAAGCATC
GGCATCAGCATCATTATGATTCTGTTATATGTGGCGGCGCTGTACTTTAAACTTGTCACGCATCGGGGCGTTTATCAGCC
GAATAATGCCGCTCAGACTGAAGAAGAGGAAGAGCCAGAATGGTCAGGGAAGGTTGCGACGATTGTCTTGTTTGCGGCAA
CGATTGTGGTTGCATACATATCCGAAAACCTGGTCCATACCTTTCACTCGGTGGCTGAACAGTTCGGGTGGAGCGAGCTG
TTTATTGGGGTCATCATCGTGGCGATTGTAGGAAATGCGGCGGAGCATGCGTCAGCGATTATTATGGCCTTCAAAAATAA
AATGGACATTGCTGTTGAAATTGCAGTAGGCTCTACGCTGCAGATCGCTATGTTTGTCGCACCGGTTCTCGTCATCTGTT
CTATCTTTTTTCCGACAAGCATGCCGCTTGTATTTACATTGCCTGAGCTCGTCGCGATGGTATCAGCGGTTCTCTTGATG
ATCGCGATTTCGAATGACGGGGATTCCAACTGGTTTGAAGGGGCGACACTGCTTGCTGCATATGTCATTATGGCGATCGG
CTTTTTCCTTCTTTAA

Upstream 100 bases:

>100_bases
AAAAAGCCTATATCACGCTATACATTTGCCCTCGTGTAATCATGAAGGTTTTTGTGAAGAATAAAAATAAAACAAGTCAT
AAAAAAGGAGCTATTTCACC

Downstream 100 bases:

>100_bases
CCTGAAAAAATGATGGATAACAACAAAGCGGGATGAAAAGACTAAGGGAAAATGCCATAGAAAGAGTGATATGATGAAAA
AGCTATTTCATTCCACACTT

Product: H+/Ca2+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNRIFFILVAAGVPLSVIGSLMHWPSAVLFAVYCVTIIALASYMGRATESLSIIAGPRIGGLLNATFGNAVELIISLFAL
KEGLTGIVLASLTGSVLGNLLLVAGLSFFVGGLKYKRQEFNIHDARHNSGLLIFAIIVAFVIPEVFSVGMGNASKLNLSI
GISIIMILLYVAALYFKLVTHRGVYQPNNAAQTEEEEEPEWSGKVATIVLFAATIVVAYISENLVHTFHSVAEQFGWSEL
FIGVIIVAIVGNAAEHASAIIMAFKNKMDIAVEIAVGSTLQIAMFVAPVLVICSIFFPTSMPLVFTLPELVAMVSAVLLM
IAISNDGDSNWFEGATLLAAYVIMAIGFFLL

Sequences:

>Translated_351_residues
MNRIFFILVAAGVPLSVIGSLMHWPSAVLFAVYCVTIIALASYMGRATESLSIIAGPRIGGLLNATFGNAVELIISLFAL
KEGLTGIVLASLTGSVLGNLLLVAGLSFFVGGLKYKRQEFNIHDARHNSGLLIFAIIVAFVIPEVFSVGMGNASKLNLSI
GISIIMILLYVAALYFKLVTHRGVYQPNNAAQTEEEEEPEWSGKVATIVLFAATIVVAYISENLVHTFHSVAEQFGWSEL
FIGVIIVAIVGNAAEHASAIIMAFKNKMDIAVEIAVGSTLQIAMFVAPVLVICSIFFPTSMPLVFTLPELVAMVSAVLLM
IAISNDGDSNWFEGATLLAAYVIMAIGFFLL
>Mature_351_residues
MNRIFFILVAAGVPLSVIGSLMHWPSAVLFAVYCVTIIALASYMGRATESLSIIAGPRIGGLLNATFGNAVELIISLFAL
KEGLTGIVLASLTGSVLGNLLLVAGLSFFVGGLKYKRQEFNIHDARHNSGLLIFAIIVAFVIPEVFSVGMGNASKLNLSI
GISIIMILLYVAALYFKLVTHRGVYQPNNAAQTEEEEEPEWSGKVATIVLFAATIVVAYISENLVHTFHSVAEQFGWSEL
FIGVIIVAIVGNAAEHASAIIMAFKNKMDIAVEIAVGSTLQIAMFVAPVLVICSIFFPTSMPLVFTLPELVAMVSAVLLM
IAISNDGDSNWFEGATLLAAYVIMAIGFFLL

Specific function: Unknown

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family

Homologues:

Organism=Saccharomyces cerevisiae, GI6320075, Length=355, Percent_Identity=39.7183098591549, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6324008, Length=390, Percent_Identity=29.7435897435897, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFKE_BACSU (O34840)

Other databases:

- EMBL:   D83967
- EMBL:   AL009126
- PIR:   A69808
- RefSeq:   NP_388673.1
- ProteinModelPortal:   O34840
- EnsemblBacteria:   EBBACT00000002001
- GeneID:   939693
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU07920
- NMPDR:   fig|224308.1.peg.792
- GenoList:   BSU07920
- GeneTree:   EBGT00050000001411
- HOGENOM:   HBG738140
- OMA:   FVIPEVF
- PhylomeDB:   O34840
- ProtClustDB:   CLSK880953
- BioCyc:   BSUB:BSU07920-MONOMER
- InterPro:   IPR004713
- InterPro:   IPR004798
- InterPro:   IPR004837
- TIGRFAMs:   TIGR00846
- TIGRFAMs:   TIGR00378

Pfam domain/function: PF01699 Na_Ca_ex

EC number: NA

Molecular weight: Translated: 37522; Mature: 37522

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcb70134)-; HASH(0xdb22af0)-; HASH(0xd1ce5e0)-; HASH(0xbab17f8)-; HASH(0xcbc4890)-; HASH(0xd9c34a8)-; HASH(0xd51f4e4)-; HASH(0xd7345b0)-; HASH(0xd38f79c)-; HASH(0xda460bc)-; HASH(0xda7205c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIFFILVAAGVPLSVIGSLMHWPSAVLFAVYCVTIIALASYMGRATESLSIIAGPRIG
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEEECCCCC
GLLNATFGNAVELIISLFALKEGLTGIVLASLTGSVLGNLLLVAGLSFFVGGLKYKRQEF
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NIHDARHNSGLLIFAIIVAFVIPEVFSVGMGNASKLNLSIGISIIMILLYVAALYFKLVT
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
HRGVYQPNNAAQTEEEEEPEWSGKVATIVLFAATIVVAYISENLVHTFHSVAEQFGWSEL
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
FIGVIIVAIVGNAAEHASAIIMAFKNKMDIAVEIAVGSTLQIAMFVAPVLVICSIFFPTS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
MPLVFTLPELVAMVSAVLLMIAISNDGDSNWFEGATLLAAYVIMAIGFFLL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MNRIFFILVAAGVPLSVIGSLMHWPSAVLFAVYCVTIIALASYMGRATESLSIIAGPRIG
CCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEEECCCCC
GLLNATFGNAVELIISLFALKEGLTGIVLASLTGSVLGNLLLVAGLSFFVGGLKYKRQEF
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NIHDARHNSGLLIFAIIVAFVIPEVFSVGMGNASKLNLSIGISIIMILLYVAALYFKLVT
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
HRGVYQPNNAAQTEEEEEPEWSGKVATIVLFAATIVVAYISENLVHTFHSVAEQFGWSEL
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
FIGVIIVAIVGNAAEHASAIIMAFKNKMDIAVEIAVGSTLQIAMFVAPVLVICSIFFPTS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
MPLVFTLPELVAMVSAVLLMIAISNDGDSNWFEGATLLAAYVIMAIGFFLL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377