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The map label for this gene is nuoA

Identifier: 159901491

GI number: 159901491

Start: 6316840

End: 6317196

Strand: Direct

Name: nuoA

Synonym: Haur_4980

Alternate gene names: 159901491

Gene position: 6316840-6317196 (Clockwise)

Preceding gene: 159901490

Following gene: 159901492

Centisome position: 99.53

GC content: 48.74

Gene sequence:

>357_bases
ATGCTTACAAACTATGCGTTTATCGGGATCTTCGCGCTTGCCGCGATCACCTTTCCGCTCTTGCCGCTGGTGCTGTCGGC
CTTTTTACGGCCCAACCGACCCACACCAGTCAAGCTTTCGACCTACGAGTGTGGTTTGGAGGCGATTGGCGATATCTGGG
TCCAATTCAAAGTTCAATACTACTTGTATGCTTTGGCCTTTGTGATTTTCGATATCGAAACGGTCTTTTTGTATCCATGG
GCAGTGGCCTATGGGCAACTGGGCTTGTTTGCCCTCTTTGAAATGGTGGTCTTTTTAGCAATTCTGACCATCGGTTTGGT
GTATGCCTGGAAAAAAGGCGCACTTGAGTGGATCTAA

Upstream 100 bases:

>100_bases
ATGGCTGCACGGTGTTAGTGCAATTATGTACAGCGAGTACTGGGGCTTACCCGTCTCGCTCTTTGTGTGTTTGTAACAGG
CATCACTAGGAGACCGACCT

Downstream 100 bases:

>100_bases
ACGACGAATAGGGGAGTGACGGCGCGGAGGCGGCGCGGCTGCGCTGGGCCTTGGCCTAATTCAATTCACCATTTTGCCCG
GAGGGCGTATGTCTGATCTA

Product: NADH-ubiquinone/plastoquinone oxidoreductase subunit 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MLTNYAFIGIFALAAITFPLLPLVLSAFLRPNRPTPVKLSTYECGLEAIGDIWVQFKVQYYLYALAFVIFDIETVFLYPW
AVAYGQLGLFALFEMVVFLAILTIGLVYAWKKGALEWI

Sequences:

>Translated_118_residues
MLTNYAFIGIFALAAITFPLLPLVLSAFLRPNRPTPVKLSTYECGLEAIGDIWVQFKVQYYLYALAFVIFDIETVFLYPW
AVAYGQLGLFALFEMVVFLAILTIGLVYAWKKGALEWI
>Mature_118_residues
MLTNYAFIGIFALAAITFPLLPLVLSAFLRPNRPTPVKLSTYECGLEAIGDIWVQFKVQYYLYALAFVIFDIETVFLYPW
AVAYGQLGLFALFEMVVFLAILTIGLVYAWKKGALEWI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_HERA2 (A9B477)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001547738.1
- GeneID:   5736816
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4980
- HOGENOM:   HBG605540
- OMA:   GERELTY
- ProtClustDB:   CLSK974497
- BioCyc:   HAUR316274:HAUR_4980-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13397; Mature: 13397

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x40cf538c)-; HASH(0x1ab38130)-; HASH(0x1a8aed08)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNYAFIGIFALAAITFPLLPLVLSAFLRPNRPTPVKLSTYECGLEAIGDIWVQFKVQY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
YLYALAFVIFDIETVFLYPWAVAYGQLGLFALFEMVVFLAILTIGLVYAWKKGALEWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MLTNYAFIGIFALAAITFPLLPLVLSAFLRPNRPTPVKLSTYECGLEAIGDIWVQFKVQY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
YLYALAFVIFDIETVFLYPWAVAYGQLGLFALFEMVVFLAILTIGLVYAWKKGALEWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA