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The map label for this gene is luxQ [H]

Identifier: 159901418

GI number: 159901418

Start: 6244099

End: 6245772

Strand: Direct

Name: luxQ [H]

Synonym: Haur_4907

Alternate gene names: 159901418

Gene position: 6244099-6245772 (Clockwise)

Preceding gene: 159901417

Following gene: 159901419

Centisome position: 98.39

GC content: 49.28

Gene sequence:

>1674_bases
ATGCGGCTTTCTTTTCGCACAAAATTGCTTGGCTCAATTGCCCTCGACTTGGCCTTGATGATCGCCTTGGGTGTTTTTGC
GTTAAACGGCTTTAGCAACGTTTTTCAAAAAGCCTCAATGATTGAGCAAATTACCATTCCTTCACTCGATTTGAGCGATC
GGATTAATTTTATCAGCACAAAATATCATGCCTTGCAGCTTGAATATATTATAAACAATAGTGATGCTGATAAAGCCCGC
ATCGAAGGCGAAATGCAAGCGTTCGAGCAACAAATGGATAATGCGTTTGCTGCATATCGCCAACTTGATACCACTATGGT
CGAAGGCGAAACCTTGAACGCGGTGGCGATGGCTTGGCAACGCTTTGTGCAAGAAACCAATGAACAATTTTTGCCAACTG
CGCGTTTGAGCAATACTGGCAGTGTACAGCCAGCGCTCAATCGCCTCAATCCCTATTACGAAGATGTGCTTAGTGCCACC
GATATTTTGGGTCAGTTGAGCCAAAATCAAGCCAACGAGGCCTTGGTTTCGGTTGGTCAAACCTTTGAATCAGCGCGTTT
GGTGATTTATGGCGAAATTGCTTTTACTGTGCTGCTTTCGGGGGCAATTGGCTTGATGTTGGCAACCCGCACGGCACGAC
GGATTCGTAATCTGACTGATGCCACCGTGGCTGTGGCTGGTGGTGATTTGGAACGCACGGTGCAAGTGCGTGGCGGCGAT
GAATTGCAAACCTTGGCAAGCAACTTCAACAGCATGGTGCGCAGCTTGCGCGAACATCGCGATATGCTTGAACTGCGCAA
TGCTGAACTGGCCGAGAGTTTGTATGTGCAACAACAATTGACCGAGGATATTATTCGGCGCAAGCAGGCCGAAGAGATTG
CTTTACGCGCTCAGGCAGCAGCCGAAGCGGCGAGCCAAGCCAAAAGTATGTTTGTGGCAACCATGAGCCACGAATTGCGC
ACCCCGTTGAATGCAATTTTGGGCTATACCCAACTCCTGCATCTCGGAGCCAAAGCGCGAGGTCAAGAAGATGTTTTGCC
ACAGCTTGAGCGAATTCGCTTGGCGGGCAAACATCTGCTCACCTTAGTTTCAAATGTCCTCGATTTCTCCAAAATTGAGC
ATGGCAAGATGAACCTTGATCTTGGCGATGTGCAATTGGCCAGCTTAGTTGATGAAGTGATGGGGATTGTTCAGCCCTTA
GCTGAAGCTCGTTTTGATCAACTGACGACTGAATTTGCTAGCACCAGCCTGATTTACAGCGATGGTGGCAAAATTCGCCA
GATTTTATTCAACTTATTGAGCAATGCGATCAAATTTACCGAAGCTGGCACAGTGACCCTGCGCGTGTGGGATGAGCAAC
GTGCTGGCGAGCCATGGCTGATATTTGCGGTCAGCGATACTGGCATCGGTATGGCTCCTGATCAATTACGGCGTTTGTTT
AAGCCATTTGTCCAAGCCGATGAATCGACGACCCGCACCTATGGCGGGACTGGTTTAGGTTTGGCGCTTAGTCAGCAACT
TGCAGCGATGCTTGGCGGCTCGATCAGTGTTGAAAGCTGCCCCAATGTTGGCTCGACCTTTACATTGCAGATACCCGTTC
AATGTCCAGAGCAATCTGAAGCTACGCTGGTGATGGCAGCATCGCCACTGGTTAATTCGAGCGCTGTGGCCTGA

Upstream 100 bases:

>100_bases
AGAGCGCGTGCAACAACGCAAACTTGGCTCGTTGTTCGAGGGTGGTTCGCAAATCGGGGTTTCGATCGAACGCTTGCTTG
AGCTAGAAGGACAATAAGCG

Downstream 100 bases:

>100_bases
TACCCAACCAACTTAGGAGGATTCCCATGGGGATGATTTTAGTTGTTGATGATAATGGCGATAATCGTTTCTTGCTTCAA
CAGATGTTATCGTTGAATGG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MRLSFRTKLLGSIALDLALMIALGVFALNGFSNVFQKASMIEQITIPSLDLSDRINFISTKYHALQLEYIINNSDADKAR
IEGEMQAFEQQMDNAFAAYRQLDTTMVEGETLNAVAMAWQRFVQETNEQFLPTARLSNTGSVQPALNRLNPYYEDVLSAT
DILGQLSQNQANEALVSVGQTFESARLVIYGEIAFTVLLSGAIGLMLATRTARRIRNLTDATVAVAGGDLERTVQVRGGD
ELQTLASNFNSMVRSLREHRDMLELRNAELAESLYVQQQLTEDIIRRKQAEEIALRAQAAAEAASQAKSMFVATMSHELR
TPLNAILGYTQLLHLGAKARGQEDVLPQLERIRLAGKHLLTLVSNVLDFSKIEHGKMNLDLGDVQLASLVDEVMGIVQPL
AEARFDQLTTEFASTSLIYSDGGKIRQILFNLLSNAIKFTEAGTVTLRVWDEQRAGEPWLIFAVSDTGIGMAPDQLRRLF
KPFVQADESTTRTYGGTGLGLALSQQLAAMLGGSISVESCPNVGSTFTLQIPVQCPEQSEATLVMAASPLVNSSAVA

Sequences:

>Translated_557_residues
MRLSFRTKLLGSIALDLALMIALGVFALNGFSNVFQKASMIEQITIPSLDLSDRINFISTKYHALQLEYIINNSDADKAR
IEGEMQAFEQQMDNAFAAYRQLDTTMVEGETLNAVAMAWQRFVQETNEQFLPTARLSNTGSVQPALNRLNPYYEDVLSAT
DILGQLSQNQANEALVSVGQTFESARLVIYGEIAFTVLLSGAIGLMLATRTARRIRNLTDATVAVAGGDLERTVQVRGGD
ELQTLASNFNSMVRSLREHRDMLELRNAELAESLYVQQQLTEDIIRRKQAEEIALRAQAAAEAASQAKSMFVATMSHELR
TPLNAILGYTQLLHLGAKARGQEDVLPQLERIRLAGKHLLTLVSNVLDFSKIEHGKMNLDLGDVQLASLVDEVMGIVQPL
AEARFDQLTTEFASTSLIYSDGGKIRQILFNLLSNAIKFTEAGTVTLRVWDEQRAGEPWLIFAVSDTGIGMAPDQLRRLF
KPFVQADESTTRTYGGTGLGLALSQQLAAMLGGSISVESCPNVGSTFTLQIPVQCPEQSEATLVMAASPLVNSSAVA
>Mature_557_residues
MRLSFRTKLLGSIALDLALMIALGVFALNGFSNVFQKASMIEQITIPSLDLSDRINFISTKYHALQLEYIINNSDADKAR
IEGEMQAFEQQMDNAFAAYRQLDTTMVEGETLNAVAMAWQRFVQETNEQFLPTARLSNTGSVQPALNRLNPYYEDVLSAT
DILGQLSQNQANEALVSVGQTFESARLVIYGEIAFTVLLSGAIGLMLATRTARRIRNLTDATVAVAGGDLERTVQVRGGD
ELQTLASNFNSMVRSLREHRDMLELRNAELAESLYVQQQLTEDIIRRKQAEEIALRAQAAAEAASQAKSMFVATMSHELR
TPLNAILGYTQLLHLGAKARGQEDVLPQLERIRLAGKHLLTLVSNVLDFSKIEHGKMNLDLGDVQLASLVDEVMGIVQPL
AEARFDQLTTEFASTSLIYSDGGKIRQILFNLLSNAIKFTEAGTVTLRVWDEQRAGEPWLIFAVSDTGIGMAPDQLRRLF
KPFVQADESTTRTYGGTGLGLALSQQLAAMLGGSISVESCPNVGSTFTLQIPVQCPEQSEATLVMAASPLVNSSAVA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=361, Percent_Identity=35.7340720221607, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789149, Length=368, Percent_Identity=34.7826086956522, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI145693157, Length=318, Percent_Identity=34.2767295597484, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=38.1889763779528, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788713, Length=308, Percent_Identity=31.8181818181818, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1788549, Length=260, Percent_Identity=30.3846153846154, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=30.5439330543933, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788393, Length=326, Percent_Identity=25.7668711656442, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=29.5652173913043, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=31.7829457364341, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=28.0701754385965, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=26.3829787234043, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=24.7826086956522, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789808, Length=290, Percent_Identity=24.4827586206897, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=23.5807860262009, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1788545, Length=279, Percent_Identity=26.8817204301075, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=77, Percent_Identity=46.7532467532467, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60972; Mature: 60972

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSFRTKLLGSIALDLALMIALGVFALNGFSNVFQKASMIEQITIPSLDLSDRINFIST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
KYHALQLEYIINNSDADKARIEGEMQAFEQQMDNAFAAYRQLDTTMVEGETLNAVAMAWQ
HHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RFVQETNEQFLPTARLSNTGSVQPALNRLNPYYEDVLSATDILGQLSQNQANEALVSVGQ
HHHHHHCHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
TFESARLVIYGEIAFTVLLSGAIGLMLATRTARRIRNLTDATVAVAGGDLERTVQVRGGD
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCH
ELQTLASNFNSMVRSLREHRDMLELRNAELAESLYVQQQLTEDIIRRKQAEEIALRAQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAASQAKSMFVATMSHELRTPLNAILGYTQLLHLGAKARGQEDVLPQLERIRLAGKHLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TLVSNVLDFSKIEHGKMNLDLGDVQLASLVDEVMGIVQPLAEARFDQLTTEFASTSLIYS
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
DGGKIRQILFNLLSNAIKFTEAGTVTLRVWDEQRAGEPWLIFAVSDTGIGMAPDQLRRLF
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHH
KPFVQADESTTRTYGGTGLGLALSQQLAAMLGGSISVESCPNVGSTFTLQIPVQCPEQSE
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEECCCCCCCC
ATLVMAASPLVNSSAVA
CEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRLSFRTKLLGSIALDLALMIALGVFALNGFSNVFQKASMIEQITIPSLDLSDRINFIST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
KYHALQLEYIINNSDADKARIEGEMQAFEQQMDNAFAAYRQLDTTMVEGETLNAVAMAWQ
HHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RFVQETNEQFLPTARLSNTGSVQPALNRLNPYYEDVLSATDILGQLSQNQANEALVSVGQ
HHHHHHCHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
TFESARLVIYGEIAFTVLLSGAIGLMLATRTARRIRNLTDATVAVAGGDLERTVQVRGGD
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCH
ELQTLASNFNSMVRSLREHRDMLELRNAELAESLYVQQQLTEDIIRRKQAEEIALRAQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAASQAKSMFVATMSHELRTPLNAILGYTQLLHLGAKARGQEDVLPQLERIRLAGKHLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TLVSNVLDFSKIEHGKMNLDLGDVQLASLVDEVMGIVQPLAEARFDQLTTEFASTSLIYS
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
DGGKIRQILFNLLSNAIKFTEAGTVTLRVWDEQRAGEPWLIFAVSDTGIGMAPDQLRRLF
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHH
KPFVQADESTTRTYGGTGLGLALSQQLAAMLGGSISVESCPNVGSTFTLQIPVQCPEQSE
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEECCCCCCCC
ATLVMAASPLVNSSAVA
CEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]