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The map label for this gene is rfbB [C]

Identifier: 159900836

GI number: 159900836

Start: 5520757

End: 5522289

Strand: Direct

Name: rfbB [C]

Synonym: Haur_4323

Alternate gene names: 159900836

Gene position: 5520757-5522289 (Clockwise)

Preceding gene: 159900835

Following gene: 159900837

Centisome position: 86.99

GC content: 50.1

Gene sequence:

>1533_bases
GTGGCAGCTAGCGAAAGGAGCACTGCCTTGAAATTCTCACGCGCAATTGCTACGCGCCTTTTGGTCGATGCAATTCTCAT
CAATGTGGGCTTGTTATTGGCCTTTGTAGTGCGCTATATTACGATTGTAATCCATGAGCCAAATTTGGCTGAACGCTTGA
TTTTGGATTATCGCGACCAATTTTTGAGCACCAGTTGGCTACTGACCAGCCTCGCGTTGGCTTTGCTGTGGATGTTTGGG
GTCTATCACCATGTGCGCAGCTATGCCCGTCGCTTCAAAGTAATGACCTTATTACAAGCCACCACGCTCGCCCATCTCGC
TTATGGATTTAGCTTTTTCTTTCTGCGCTTCTTGCCGTTTGTTCCGCGTGGGGTGGTGGTGCTGAGCTGGGTATTTACTT
CGGCGTTGGTCATTGGCATTCGCATCGCCCGCAATGTGGTGTTGGCAGTCGATGCCTTAGAACGCCAAACTCCCAAGGCC
GATCAGCCGATTAAACATGTATTGGTCATTGGCGGGGCGGGCTATATTGGCTCGTTGGTGCTACGTCGCCTGCTCAATCA
AGGCTATCATGTGCGGTTGGTCGATTCGCTGATGTATGGCGATGGGGCCATCCGCGAGCTTTACAATCATCCGCAATTTG
AATTTGTCCATGGCGATATGCGCCACATCGAAACCGTGGTGCGCTCGTTGGTTGGAATGGATGCGGTGATTCACCTTGGG
GCGATTGTTGGCGACCCTGCCTGTGCGATCGATGCCGATTTCAGCACTGAAATTAATTTGATTGCCACGCGAATGTTGGC
TGAAGCGTGCAAAGGCTATGGAATTCGGCGCTTTATTTTTGCCTCAACCTGTAGCGTGTATGGCGCATCGGATGAATTGC
TCGATGAGCGTTCGGCGCTTAATCCAGTTTCGCTCTATGCCCAAACCAAAATCGACTCAGAAAATATTTTGTTGGGCTTA
GCAGATCAACAATTTGCTCCAACGATTCTGCGTTTTTCGACAATTTATGGCCTATCGCCGCGCCCGCGCTTTGATTTGGT
GGTCAATTTACTAACCGCCAAAGCTGTACGTGAGGGCAAAATCACGGTGTTTGGTGGTGATCAATGGCGGCCATTTGTGC
ATGCCGATGATGCCGCCCGCGCGGTAGTGATGAGCTTGAATGCGCCTTTAGCAGCCGTGCGCGGCGAGATTTTCAATGTT
GGCTCGGATAGTCAAAACTACACCATCAGCGCGATTGGCGAATTGATTGGGCGTTTAATTCCTGAGGCCGAGTTGGTATT
GCAAGGCAACGATGTTGATAAACGTAACTATCGCGTTTCGTTCGCCAAAATTGCCAAAGTACTCAATTTCAGCCCTGAAC
ACACGGTTGAGGATGGGGTACGCGAAATCGAAGCGGCTTTGCGTGATGGATCAATTGGCGATTATTACGACCCAGCCTAT
AACAACCACAAATTCCTGACGAATGTTGATAATGCGCCGTTGATTCGGCTAGAAACGCCATGGGCCAACAAACGTGAGTC
GATCAAGCAATGA

Upstream 100 bases:

>100_bases
ATAACCTGCTTCGTTTAACGCAGAGGCGCAGAGGTTATTGTAGTTCCAATTGAAAACTCTGCGTCTCTGCGTTATGAATG
ACTGATTCAAGGTCACCGTT

Downstream 100 bases:

>100_bases
GCGAGCCTGCCGTGGAATTGTTGTTGGCGGCATGGTCAAGCCAACCAGCCGCCAACTTAACGCAATTATGTGCTGCATGT
AGTCCAAACGACTGGAAAGT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MAASERSTALKFSRAIATRLLVDAILINVGLLLAFVVRYITIVIHEPNLAERLILDYRDQFLSTSWLLTSLALALLWMFG
VYHHVRSYARRFKVMTLLQATTLAHLAYGFSFFFLRFLPFVPRGVVVLSWVFTSALVIGIRIARNVVLAVDALERQTPKA
DQPIKHVLVIGGAGYIGSLVLRRLLNQGYHVRLVDSLMYGDGAIRELYNHPQFEFVHGDMRHIETVVRSLVGMDAVIHLG
AIVGDPACAIDADFSTEINLIATRMLAEACKGYGIRRFIFASTCSVYGASDELLDERSALNPVSLYAQTKIDSENILLGL
ADQQFAPTILRFSTIYGLSPRPRFDLVVNLLTAKAVREGKITVFGGDQWRPFVHADDAARAVVMSLNAPLAAVRGEIFNV
GSDSQNYTISAIGELIGRLIPEAELVLQGNDVDKRNYRVSFAKIAKVLNFSPEHTVEDGVREIEAALRDGSIGDYYDPAY
NNHKFLTNVDNAPLIRLETPWANKRESIKQ

Sequences:

>Translated_510_residues
MAASERSTALKFSRAIATRLLVDAILINVGLLLAFVVRYITIVIHEPNLAERLILDYRDQFLSTSWLLTSLALALLWMFG
VYHHVRSYARRFKVMTLLQATTLAHLAYGFSFFFLRFLPFVPRGVVVLSWVFTSALVIGIRIARNVVLAVDALERQTPKA
DQPIKHVLVIGGAGYIGSLVLRRLLNQGYHVRLVDSLMYGDGAIRELYNHPQFEFVHGDMRHIETVVRSLVGMDAVIHLG
AIVGDPACAIDADFSTEINLIATRMLAEACKGYGIRRFIFASTCSVYGASDELLDERSALNPVSLYAQTKIDSENILLGL
ADQQFAPTILRFSTIYGLSPRPRFDLVVNLLTAKAVREGKITVFGGDQWRPFVHADDAARAVVMSLNAPLAAVRGEIFNV
GSDSQNYTISAIGELIGRLIPEAELVLQGNDVDKRNYRVSFAKIAKVLNFSPEHTVEDGVREIEAALRDGSIGDYYDPAY
NNHKFLTNVDNAPLIRLETPWANKRESIKQ
>Mature_509_residues
AASERSTALKFSRAIATRLLVDAILINVGLLLAFVVRYITIVIHEPNLAERLILDYRDQFLSTSWLLTSLALALLWMFGV
YHHVRSYARRFKVMTLLQATTLAHLAYGFSFFFLRFLPFVPRGVVVLSWVFTSALVIGIRIARNVVLAVDALERQTPKAD
QPIKHVLVIGGAGYIGSLVLRRLLNQGYHVRLVDSLMYGDGAIRELYNHPQFEFVHGDMRHIETVVRSLVGMDAVIHLGA
IVGDPACAIDADFSTEINLIATRMLAEACKGYGIRRFIFASTCSVYGASDELLDERSALNPVSLYAQTKIDSENILLGLA
DQQFAPTILRFSTIYGLSPRPRFDLVVNLLTAKAVREGKITVFGGDQWRPFVHADDAARAVVMSLNAPLAAVRGEIFNVG
SDSQNYTISAIGELIGRLIPEAELVLQGNDVDKRNYRVSFAKIAKVLNFSPEHTVEDGVREIEAALRDGSIGDYYDPAYN
NHKFLTNVDNAPLIRLETPWANKRESIKQ

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=268, Percent_Identity=28.7313432835821, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI193211614, Length=229, Percent_Identity=28.3842794759825, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI8393516, Length=229, Percent_Identity=28.3842794759825, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788353, Length=342, Percent_Identity=27.7777777777778, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI48994969, Length=340, Percent_Identity=25.8823529411765, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788589, Length=277, Percent_Identity=25.9927797833935, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786974, Length=276, Percent_Identity=26.8115942028986, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=24.9230769230769, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=313, Percent_Identity=23.961661341853, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532424, Length=339, Percent_Identity=26.2536873156342, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=267, Percent_Identity=28.8389513108614, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356223, Length=343, Percent_Identity=23.3236151603499, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 56766; Mature: 56635

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASERSTALKFSRAIATRLLVDAILINVGLLLAFVVRYITIVIHEPNLAERLILDYRDQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
FLSTSWLLTSLALALLWMFGVYHHVRSYARRFKVMTLLQATTLAHLAYGFSFFFLRFLPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPRGVVVLSWVFTSALVIGIRIARNVVLAVDALERQTPKADQPIKHVLVIGGAGYIGSLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHH
LRRLLNQGYHVRLVDSLMYGDGAIRELYNHPQFEFVHGDMRHIETVVRSLVGMDAVIHLG
HHHHHCCCCEEEEEHHHHHCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
AIVGDPACAIDADFSTEINLIATRMLAEACKGYGIRRFIFASTCSVYGASDELLDERSAL
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCC
NPVSLYAQTKIDSENILLGLADQQFAPTILRFSTIYGLSPRPRFDLVVNLLTAKAVREGK
CHHHEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCE
ITVFGGDQWRPFVHADDAARAVVMSLNAPLAAVRGEIFNVGSDSQNYTISAIGELIGRLI
EEEEECCCCCCCEECCCHHHEEEEECCCCHHHHCCHHEECCCCCCCCHHHHHHHHHHHHC
PEAELVLQGNDVDKRNYRVSFAKIAKVLNFSPEHTVEDGVREIEAALRDGSIGDYYDPAY
CCCEEEEECCCCCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NNHKFLTNVDNAPLIRLETPWANKRESIKQ
CCCCEEEECCCCCEEEEECCCCCCHHHCCC
>Mature Secondary Structure 
AASERSTALKFSRAIATRLLVDAILINVGLLLAFVVRYITIVIHEPNLAERLILDYRDQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
FLSTSWLLTSLALALLWMFGVYHHVRSYARRFKVMTLLQATTLAHLAYGFSFFFLRFLPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPRGVVVLSWVFTSALVIGIRIARNVVLAVDALERQTPKADQPIKHVLVIGGAGYIGSLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHH
LRRLLNQGYHVRLVDSLMYGDGAIRELYNHPQFEFVHGDMRHIETVVRSLVGMDAVIHLG
HHHHHCCCCEEEEEHHHHHCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
AIVGDPACAIDADFSTEINLIATRMLAEACKGYGIRRFIFASTCSVYGASDELLDERSAL
HHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCC
NPVSLYAQTKIDSENILLGLADQQFAPTILRFSTIYGLSPRPRFDLVVNLLTAKAVREGK
CHHHEEEEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCE
ITVFGGDQWRPFVHADDAARAVVMSLNAPLAAVRGEIFNVGSDSQNYTISAIGELIGRLI
EEEEECCCCCCCEECCCHHHEEEEECCCCHHHHCCHHEECCCCCCCCHHHHHHHHHHHHC
PEAELVLQGNDVDKRNYRVSFAKIAKVLNFSPEHTVEDGVREIEAALRDGSIGDYYDPAY
CCCEEEEECCCCCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NNHKFLTNVDNAPLIRLETPWANKRESIKQ
CCCCEEEECCCCCEEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]