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The map label for this gene is degU [H]

Identifier: 159900552

GI number: 159900552

Start: 5155931

End: 5156683

Strand: Reverse

Name: degU [H]

Synonym: Haur_4039

Alternate gene names: 159900552

Gene position: 5156683-5155931 (Counterclockwise)

Preceding gene: 159900561

Following gene: 159900551

Centisome position: 81.25

GC content: 45.15

Gene sequence:

>753_bases
GTGGATCGTATGCAAGCATCTGCGGAAAACTCGCGCCGACGTGGCGAGTCGAGCGCCAAAACCAATATTGTGTTGGTTCA
TGCCCATACAATTTATCGTGAAGGCTTACGCTATCATTTCGGCCAAGTACCACGCTATAAAATTATTGGTGAGGCCAGCA
ATGGACAGCAAGCCATTCGTTTGGTCGATTATAGTAACCCCGATATTATTGTGATGGATGTCGATTTACCAGGGGTCAAC
GGAATTGAAGTCGCTCGCACAGTCAAATTAAATCATCCCAATATTGGCGTAATTTTGCTCAGTGATATCAACGATCAAGA
AGGTATTGTAAAATCATTGCGAGCAGGTGTGGCCGCCTATCTTTCACGCACAATCGATTGGGATGATCTGATCAATTCGG
TCGATATGGTGCGCTCTGGCAATTATCCAATTAATGATTTGGTGCTGAATACCCCAGCGGTCGCTGCTGCTGTGATGGAT
TCGTTTCGCCAATTGACTATGGATACGCATACCGAGCATGTCTACTCGCCAATGTCACCGCGTGAAATTGAAGTTTTGGA
ATTGGTAGCGGCGGGGCAAACCAATAAAGAAATTGCCGCCCGCCTCGAAATTAGCAATCAAACTGTCAAAAATCATATTT
CATCAATTTTGCGCAAATTGGCGGTCAACGATCGCACCCAAGCTGTGGTATTTGCATTACAGCGCGGCTGGATTAAAATT
GTGCAAAACGATAATTCGTTTTCTGGCATGTAA

Upstream 100 bases:

>100_bases
ATCCCACTAACGTTTAACCTCAATCAATGCTGATGCTCGTCGTCGTGTATAATTGCGCATATCATCGCTTACCGAGGGTA
TGCCTAGGATTCCAGAAAGA

Downstream 100 bases:

>100_bases
TTGCGGCGTTAGCGCCGATTTGGATTGTCCAAGGAGTGTCGTTTGAAGTTGTTGTTACGGCAACGTGTGAGTTTAGCCTT
GGTTGTTGTGGCGCTCGCAG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MDRMQASAENSRRRGESSAKTNIVLVHAHTIYREGLRYHFGQVPRYKIIGEASNGQQAIRLVDYSNPDIIVMDVDLPGVN
GIEVARTVKLNHPNIGVILLSDINDQEGIVKSLRAGVAAYLSRTIDWDDLINSVDMVRSGNYPINDLVLNTPAVAAAVMD
SFRQLTMDTHTEHVYSPMSPREIEVLELVAAGQTNKEIAARLEISNQTVKNHISSILRKLAVNDRTQAVVFALQRGWIKI
VQNDNSFSGM

Sequences:

>Translated_250_residues
MDRMQASAENSRRRGESSAKTNIVLVHAHTIYREGLRYHFGQVPRYKIIGEASNGQQAIRLVDYSNPDIIVMDVDLPGVN
GIEVARTVKLNHPNIGVILLSDINDQEGIVKSLRAGVAAYLSRTIDWDDLINSVDMVRSGNYPINDLVLNTPAVAAAVMD
SFRQLTMDTHTEHVYSPMSPREIEVLELVAAGQTNKEIAARLEISNQTVKNHISSILRKLAVNDRTQAVVFALQRGWIKI
VQNDNSFSGM
>Mature_250_residues
MDRMQASAENSRRRGESSAKTNIVLVHAHTIYREGLRYHFGQVPRYKIIGEASNGQQAIRLVDYSNPDIIVMDVDLPGVN
GIEVARTVKLNHPNIGVILLSDINDQEGIVKSLRAGVAAYLSRTIDWDDLINSVDMVRSGNYPINDLVLNTPAVAAAVMD
SFRQLTMDTHTEHVYSPMSPREIEVLELVAAGQTNKEIAARLEISNQTVKNHISSILRKLAVNDRTQAVVFALQRGWIKI
VQNDNSFSGM

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=213, Percent_Identity=30.5164319248826, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788222, Length=216, Percent_Identity=25.462962962963, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788521, Length=216, Percent_Identity=28.7037037037037, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786747, Length=214, Percent_Identity=24.2990654205607, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788712, Length=192, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27775; Mature: 27775

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRMQASAENSRRRGESSAKTNIVLVHAHTIYREGLRYHFGQVPRYKIIGEASNGQQAIR
CCCCHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEE
LVDYSNPDIIVMDVDLPGVNGIEVARTVKLNHPNIGVILLSDINDQEGIVKSLRAGVAAY
EEECCCCCEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LSRTIDWDDLINSVDMVRSGNYPINDLVLNTPAVAAAVMDSFRQLTMDTHTEHVYSPMSP
HHHCCCHHHHHHHHHHHHCCCCCHHHEEECCHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
REIEVLELVAAGQTNKEIAARLEISNQTVKNHISSILRKLAVNDRTQAVVFALQRGWIKI
CHHHHHHHHHCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEE
VQNDNSFSGM
EECCCCCCCC
>Mature Secondary Structure
MDRMQASAENSRRRGESSAKTNIVLVHAHTIYREGLRYHFGQVPRYKIIGEASNGQQAIR
CCCCHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEE
LVDYSNPDIIVMDVDLPGVNGIEVARTVKLNHPNIGVILLSDINDQEGIVKSLRAGVAAY
EEECCCCCEEEEEECCCCCCCEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LSRTIDWDDLINSVDMVRSGNYPINDLVLNTPAVAAAVMDSFRQLTMDTHTEHVYSPMSP
HHHCCCHHHHHHHHHHHHCCCCCHHHEEECCHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
REIEVLELVAAGQTNKEIAARLEISNQTVKNHISSILRKLAVNDRTQAVVFALQRGWIKI
CHHHHHHHHHCCCCCHHHEEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEE
VQNDNSFSGM
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]