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The map label for this gene is argK [C]

Identifier: 159900501

GI number: 159900501

Start: 5086987

End: 5087961

Strand: Direct

Name: argK [C]

Synonym: Haur_3988

Alternate gene names: 159900501

Gene position: 5086987-5087961 (Clockwise)

Preceding gene: 159900500

Following gene: 159900502

Centisome position: 80.15

GC content: 56.51

Gene sequence:

>975_bases
GTGGAACTTGTAGCAAAGGCTCGTGCTGGCAATCGCCGTGCACTGGCCCGCTTGATAACCTTGGTTGAAGCTGGCGATGC
CCAAGCCCAAACGGCTTTGGCGGCGCTCTACCCCTACACTGGCCATGCTCATATTGTTGGGGTAACTGGCGCACCTGGCA
CTGGCAAATCGACCTTGGTAACCCAAATGGCCTTGCATTGGCGTAGCCTTGGGCGCACGGTCGCCGTGTTGGCAGTTGAC
CCAACCTCGCCATTTAGTGGTGGCGCAATTTTAGGCGATCGGATTCGCATGCAAGCGTTGGGCGGCGACAGCGGCTGTTA
TATTCGTTCGATGGCGAGCCGTGGCAGCCTTGGCGGTTTGTCGCGGGCCACTGGCGATGCGGTCAAAGCGCTCGATGCAG
CAGGTTTTGACATTGTGATTGTTGAAACTGTGGGGGCTGGTCAGGCCGAGGTCGAAATTGCCCGCGAAGCCCATACTGTG
GTGGTGGTTGAAGTGCCAGGTATGGGCGATGATATTCAGGCGATCAAGGCTGGCATTTTGGAAATTGCCGATGTGTTTGT
GGTCAATAAAGCTGATCGCGAGGGCGTTGAGCGCACAGTTCGGCAATTGCAGATGATGCTGCATCTTGGCAGTGGCGAGC
ACCGTGATGGCTGGGAGCCACCGATTGTCCAGACTGTTTCCAACACTGGCAAGAATATCGCCGAGGCGGCTGCGGCGGTC
GAACGGCATCTCGCCCACCTCAAAAGCAACAATTTGCTCGAATTGCGCGAACGCGAGCGGATTGAGCGCGAGTGGAAAGT
GATTATGCGTGAAACGTTGTTGCGCCAATTGCTGCAACGACTTGAGCCGCACGTCCATGAACAGCTACTCAAACAGATGA
GCGAGCGCCAACTCGACCCATATGCCGCCGCCAATCAAGCGATTGAAAGCGTTTTGGAATTCCCGCAATCGGCAACTCCA
TCCGGGCAAAGCTAG

Upstream 100 bases:

>100_bases
GGGATTGCGGGGATTTTCGGGCCTGGCTCTTCGACCCATGCAATTATCGATTTTATTCGTGAGCATGTTGAGCGTAGCTC
GGTAGAAGGGTAGGTTGGGC

Downstream 100 bases:

>100_bases
GAGTAGCAGGATCAAGCTTTGGCGGTTGGCAATGGATTAACATGCCCTCACCCCCTCTCCCGCACAGCAGGCGAGGGGGA
AACTCCCAATAACCCATCTC

Product: LAO/AO transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MELVAKARAGNRRALARLITLVEAGDAQAQTALAALYPYTGHAHIVGVTGAPGTGKSTLVTQMALHWRSLGRTVAVLAVD
PTSPFSGGAILGDRIRMQALGGDSGCYIRSMASRGSLGGLSRATGDAVKALDAAGFDIVIVETVGAGQAEVEIAREAHTV
VVVEVPGMGDDIQAIKAGILEIADVFVVNKADREGVERTVRQLQMMLHLGSGEHRDGWEPPIVQTVSNTGKNIAEAAAAV
ERHLAHLKSNNLLELRERERIEREWKVIMRETLLRQLLQRLEPHVHEQLLKQMSERQLDPYAAANQAIESVLEFPQSATP
SGQS

Sequences:

>Translated_324_residues
MELVAKARAGNRRALARLITLVEAGDAQAQTALAALYPYTGHAHIVGVTGAPGTGKSTLVTQMALHWRSLGRTVAVLAVD
PTSPFSGGAILGDRIRMQALGGDSGCYIRSMASRGSLGGLSRATGDAVKALDAAGFDIVIVETVGAGQAEVEIAREAHTV
VVVEVPGMGDDIQAIKAGILEIADVFVVNKADREGVERTVRQLQMMLHLGSGEHRDGWEPPIVQTVSNTGKNIAEAAAAV
ERHLAHLKSNNLLELRERERIEREWKVIMRETLLRQLLQRLEPHVHEQLLKQMSERQLDPYAAANQAIESVLEFPQSATP
SGQS
>Mature_324_residues
MELVAKARAGNRRALARLITLVEAGDAQAQTALAALYPYTGHAHIVGVTGAPGTGKSTLVTQMALHWRSLGRTVAVLAVD
PTSPFSGGAILGDRIRMQALGGDSGCYIRSMASRGSLGGLSRATGDAVKALDAAGFDIVIVETVGAGQAEVEIAREAHTV
VVVEVPGMGDDIQAIKAGILEIADVFVVNKADREGVERTVRQLQMMLHLGSGEHRDGWEPPIVQTVSNTGKNIAEAAAAV
ERHLAHLKSNNLLELRERERIEREWKVIMRETLLRQLLQRLEPHVHEQLLKQMSERQLDPYAAANQAIESVLEFPQSATP
SGQS

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=297, Percent_Identity=34.006734006734, Blast_Score=148, Evalue=7e-36,
Organism=Escherichia coli, GI1789285, Length=318, Percent_Identity=33.9622641509434, Blast_Score=165, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71994271, Length=332, Percent_Identity=29.8192771084337, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71994275, Length=274, Percent_Identity=30.2919708029197, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34801; Mature: 34801

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVAKARAGNRRALARLITLVEAGDAQAQTALAALYPYTGHAHIVGVTGAPGTGKSTLV
CCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
TQMALHWRSLGRTVAVLAVDPTSPFSGGAILGDRIRMQALGGDSGCYIRSMASRGSLGGL
HHHHHHHHHHCCEEEEEEECCCCCCCCCCEECCCEEEEECCCCCCHHHHHHHCCCCCCCC
SRATGDAVKALDAAGFDIVIVETVGAGQAEVEIAREAHTVVVVEVPGMGDDIQAIKAGIL
CHHCHHHHHHHHCCCCCEEEEEECCCCCHHHHEECCCEEEEEEEECCCCCHHHHHHHHHH
EIADVFVVNKADREGVERTVRQLQMMLHLGSGEHRDGWEPPIVQTVSNTGKNIAEAAAAV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
ERHLAHLKSNNLLELRERERIEREWKVIMRETLLRQLLQRLEPHVHEQLLKQMSERQLDP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
YAAANQAIESVLEFPQSATPSGQS
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MELVAKARAGNRRALARLITLVEAGDAQAQTALAALYPYTGHAHIVGVTGAPGTGKSTLV
CCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHH
TQMALHWRSLGRTVAVLAVDPTSPFSGGAILGDRIRMQALGGDSGCYIRSMASRGSLGGL
HHHHHHHHHHCCEEEEEEECCCCCCCCCCEECCCEEEEECCCCCCHHHHHHHCCCCCCCC
SRATGDAVKALDAAGFDIVIVETVGAGQAEVEIAREAHTVVVVEVPGMGDDIQAIKAGIL
CHHCHHHHHHHHCCCCCEEEEEECCCCCHHHHEECCCEEEEEEEECCCCCHHHHHHHHHH
EIADVFVVNKADREGVERTVRQLQMMLHLGSGEHRDGWEPPIVQTVSNTGKNIAEAAAAV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
ERHLAHLKSNNLLELRERERIEREWKVIMRETLLRQLLQRLEPHVHEQLLKQMSERQLDP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
YAAANQAIESVLEFPQSATPSGQS
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]