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The map label for this gene is qorA [H]

Identifier: 159900420

GI number: 159900420

Start: 4895961

End: 4896944

Strand: Reverse

Name: qorA [H]

Synonym: Haur_3905

Alternate gene names: 159900420

Gene position: 4896944-4895961 (Counterclockwise)

Preceding gene: 159900426

Following gene: 159900419

Centisome position: 77.16

GC content: 56.2

Gene sequence:

>984_bases
ATGAAAGCGATTGAGTTTCATGAATTTGGAGCCTTGGCAGATGTGTTGCAGTTGGTCGAACAACCAACCCCAACCGCTGG
CGCTGGCGAGGTCTTAGTCCGCCTAACTGCTCGGTCAATCAATCCATCCGATGTCTACACCATCCAAGGGACGTATGGGG
TGCGCCCAAGCTTGCCATCTGTCCCAGGTAATGAGGCCGCTGGGGTGATCGCGGCGCTCGGCGAGGGCGTTACTGGTTGG
GATGTTGGCGATCGGGTTATCCTGATGCTCGGTGCGGTTGGGACTGCTGGCACATGGCGCGAATATGCCGTGGTCAAGCC
GCAGTTTTTAGTGCCAACTCCGGCTGCCCTCACTGATGCCCAAGCTGCTTGTACCTGGGTCAACTATTTGACCGCCTGGA
TTATGAGCGATGAGTTGCAGTTGCAGCCCGATGAGCCTGTGCTGGTAACCGCTGGCGCTTCGCACTTGGGCCGTGCAATG
TTGCAATTGTCCGCAGTCCGTGGCTTCAAAGTGGTTGCAACGGTGCGCAAACCCGAGCAAGCCCAAGCCTTGCTTGATGC
TGGTGCGCTCGGCGTAATTACCCTGCCTGGCGACGACTTGGCCAAACGCTGGAAGGAAATTACCGGCCAAAAAGGCATTG
GCAAGGCCATCGATGCGGTGGCTGGCGAAACTGGTACAGCCGTCGTCAATGCTTTAGCAGCTTATGGCCAACTGATTATT
TATGGTTTGTTGAGCGGCGAGCCAATTCAAGTTGATGGCCGGATTGTGTTTAGCGAAGCGACGATTCGTGGTTTTTGGCT
GGGCCGCTGGCTCAACCGCCAAACCCCGCAAGCAATTGGCAAATTGATCGCTGAAGTCAGCGCAATGTTTGCCGATGGCC
GTTTAGCGCCGCATGTTGATACCACTGTCGCGCTTGATGATCTCGCCGGAATTGTGCGCGTGGCCACCGAAGGCGGCGCT
GGTAAAGTTGTGATTACAGGCTAG

Upstream 100 bases:

>100_bases
CAACGGCCTGCAACTCCTAGATATTGATTGACATGTCACCCCATGGGGGAGTACGATATGCTTTAGCACGCCGATGTGTG
TTTTATGCCAAAGGGATGCC

Downstream 100 bases:

>100_bases
GAGGCTCGTTGTGCATCCCAAATCCGCCAATCGCTTAGCTGGCTTTGGTACATCAATTTTTAGTGAAATAAGTGCTTTGG
CTGCGCGTTATCAAGCGATT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKAIEFHEFGALADVLQLVEQPTPTAGAGEVLVRLTARSINPSDVYTIQGTYGVRPSLPSVPGNEAAGVIAALGEGVTGW
DVGDRVILMLGAVGTAGTWREYAVVKPQFLVPTPAALTDAQAACTWVNYLTAWIMSDELQLQPDEPVLVTAGASHLGRAM
LQLSAVRGFKVVATVRKPEQAQALLDAGALGVITLPGDDLAKRWKEITGQKGIGKAIDAVAGETGTAVVNALAAYGQLII
YGLLSGEPIQVDGRIVFSEATIRGFWLGRWLNRQTPQAIGKLIAEVSAMFADGRLAPHVDTTVALDDLAGIVRVATEGGA
GKVVITG

Sequences:

>Translated_327_residues
MKAIEFHEFGALADVLQLVEQPTPTAGAGEVLVRLTARSINPSDVYTIQGTYGVRPSLPSVPGNEAAGVIAALGEGVTGW
DVGDRVILMLGAVGTAGTWREYAVVKPQFLVPTPAALTDAQAACTWVNYLTAWIMSDELQLQPDEPVLVTAGASHLGRAM
LQLSAVRGFKVVATVRKPEQAQALLDAGALGVITLPGDDLAKRWKEITGQKGIGKAIDAVAGETGTAVVNALAAYGQLII
YGLLSGEPIQVDGRIVFSEATIRGFWLGRWLNRQTPQAIGKLIAEVSAMFADGRLAPHVDTTVALDDLAGIVRVATEGGA
GKVVITG
>Mature_327_residues
MKAIEFHEFGALADVLQLVEQPTPTAGAGEVLVRLTARSINPSDVYTIQGTYGVRPSLPSVPGNEAAGVIAALGEGVTGW
DVGDRVILMLGAVGTAGTWREYAVVKPQFLVPTPAALTDAQAACTWVNYLTAWIMSDELQLQPDEPVLVTAGASHLGRAM
LQLSAVRGFKVVATVRKPEQAQALLDAGALGVITLPGDDLAKRWKEITGQKGIGKAIDAVAGETGTAVVNALAAYGQLII
YGLLSGEPIQVDGRIVFSEATIRGFWLGRWLNRQTPQAIGKLIAEVSAMFADGRLAPHVDTTVALDDLAGIVRVATEGGA
GKVVITG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=316, Percent_Identity=31.3291139240506, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI67078406, Length=282, Percent_Identity=32.6241134751773, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI18379349, Length=315, Percent_Identity=27.9365079365079, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI194239674, Length=312, Percent_Identity=27.2435897435897, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI13236495, Length=312, Percent_Identity=27.2435897435897, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI22538446, Length=307, Percent_Identity=27.6872964169381, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI22538444, Length=307, Percent_Identity=27.6872964169381, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI24308257, Length=352, Percent_Identity=25, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI194239676, Length=196, Percent_Identity=30.1020408163265, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI28557745, Length=297, Percent_Identity=27.9461279461279, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1790485, Length=244, Percent_Identity=34.8360655737705, Blast_Score=114, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17536829, Length=290, Percent_Identity=30.3448275862069, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17556000, Length=333, Percent_Identity=27.6276276276276, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17507255, Length=207, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=218, Percent_Identity=25.6880733944954, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319500, Length=316, Percent_Identity=25.9493670886076, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=250, Percent_Identity=26.4, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550423, Length=309, Percent_Identity=33.6569579288026, Blast_Score=144, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34169; Mature: 34169

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEFHEFGALADVLQLVEQPTPTAGAGEVLVRLTARSINPSDVYTIQGTYGVRPSLPS
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCC
VPGNEAAGVIAALGEGVTGWDVGDRVILMLGAVGTAGTWREYAVVKPQFLVPTPAALTDA
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCEECCCCCHHCCH
QAACTWVNYLTAWIMSDELQLQPDEPVLVTAGASHLGRAMLQLSAVRGFKVVATVRKPEQ
HHHHHHHHHHHHHHCCCCCEECCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCHH
AQALLDAGALGVITLPGDDLAKRWKEITGQKGIGKAIDAVAGETGTAVVNALAAYGQLII
HHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHEEE
YGLLSGEPIQVDGRIVFSEATIRGFWLGRWLNRQTPQAIGKLIAEVSAMFADGRLAPHVD
EEECCCCEEEECCEEEEECCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
TTVALDDLAGIVRVATEGGAGKVVITG
CCEEHHHHHHHEEEEECCCCCEEEEEC
>Mature Secondary Structure
MKAIEFHEFGALADVLQLVEQPTPTAGAGEVLVRLTARSINPSDVYTIQGTYGVRPSLPS
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCC
VPGNEAAGVIAALGEGVTGWDVGDRVILMLGAVGTAGTWREYAVVKPQFLVPTPAALTDA
CCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCEECCCCCHHCCH
QAACTWVNYLTAWIMSDELQLQPDEPVLVTAGASHLGRAMLQLSAVRGFKVVATVRKPEQ
HHHHHHHHHHHHHHCCCCCEECCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCHH
AQALLDAGALGVITLPGDDLAKRWKEITGQKGIGKAIDAVAGETGTAVVNALAAYGQLII
HHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHEEE
YGLLSGEPIQVDGRIVFSEATIRGFWLGRWLNRQTPQAIGKLIAEVSAMFADGRLAPHVD
EEECCCCEEEECCEEEEECCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
TTVALDDLAGIVRVATEGGAGKVVITG
CCEEHHHHHHHEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]