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The map label for this gene is clpX

Identifier: 159900346

GI number: 159900346

Start: 4807778

End: 4809076

Strand: Direct

Name: clpX

Synonym: Haur_3829

Alternate gene names: 159900346

Gene position: 4807778-4809076 (Clockwise)

Preceding gene: 159900345

Following gene: 159900347

Centisome position: 75.75

GC content: 51.27

Gene sequence:

>1299_bases
ATGGCGCAATCCGCCTTTATGCCACCGACCTACTACTGCTCGTTTTGCGGGCGGAACCAAGATGAAGTCGATCGCTTGGT
CACAGGTCCGGGGGCATTATTTATTTGCAACGAGTGCATTGAGCTGTTAAGCGCAATTATTGCCAACGAGGAGCGTAAAG
AAGCTCCCCATGCCCCAATTCTCCCACCAACACTGCCGATTCCCCATGCCATTCGTGATCATCTCGATGAATATGTAATT
GGCCAAGATCGGGCGAAAAAGGTGATGGCGGTGGCGGTGTACAACCACTATAAGCGGTTGCGTGCCCAAGCTCAAGGCGA
TACCGATGTCGAAATTCAAAAGAGCAATATTTTGTTAGTTGGGCCAACTGGCTCAGGCAAAACGCTGCTTGCCCAAACCC
TAGCTCGTATGCTCGATGTGCCATTTGCCATCGCCGATGCCACCGCATTAACCGAGGCTGGGTATGTTGGCGAAGATGTC
GAGACGATTCTGCTGCGCTTGATTCAAGCCGCCGATGGCGATGTTGATCGCGCTCAAATGGGCATTTTGTATATCGACGA
AATCGATAAAATTGCCCGCAAAGCCGATAATCCATCGATCACGCGTGATGTTTCGGGCGAGGGTGTGCAACAAGCTTTGC
TGAAAATCCTCGAAGGCGGGGTGGTCAATGTGCCGCCAATGCCAGGCCGCAAACATCCGCAGCAAGAATTTATTCCCTTT
GATACCACCAATGTGCTGTTTATTTGTGGTGGGGCGTTCGAAGGCTTGGAGCATCATATTGCTGAACGGATGGGTAGTGG
CGGAACCTTAGGCTTTGGCAAGACGATCGTCAAAGAAGAACGGCTCGAACGTTCTAAGAAATTGCTATCGTTGGTCAACC
CCGACGATTTGCTGCACTTTGGTTTTATTCCTGAGTTTATCGGACGTATGCCGGTTGTCGCCGCGCTCACGCCGCTCGAT
AAAGATGCCATGATGCGGATTTTGACCGAGCCACGCAACGCAATCATCAAGCAATATCAAAAAATGTTGGCGCTTGATCA
TGTGCAACTCGAAGTCAGCGGCGATGCCATGGAAGCAATCGTTGAGCGAGCGTTGGCTGGCAAAACAGGCGCTCGTGGTT
TGCGCACTGCCGTTGAAGAAATTTTGCTCGATGTGATGTTTGATTTGCCGTCGGAAACCGATGTAGTGCGCTGTGTAATT
ACCGCTGAAACGGTGCGTGATGGTGCAATGCCAACCCTGATTCGGCGAACGAGCAGCCGCAGTCGAGCTGGTAAACAACC
AACCACCAAAGCTAGTTAA

Upstream 100 bases:

>100_bases
ATTACGACCCACATTGAAGCTGGGCAACAAGATTAATTGAGCAACAAGGATGATGACGCGAGCCTCGTTGCTCGCGTCGT
CACCAATGGGAGCAATTCCA

Downstream 100 bases:

>100_bases
ACGCTATTTTGCAGTCATGATGCCTCGTTCTCGTTGAGAGCGGGGCATTTTGTTTTAGCGTTTGTTGCCATGGCTTGACA
CACTGCGTAAATCGGGGCAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MAQSAFMPPTYYCSFCGRNQDEVDRLVTGPGALFICNECIELLSAIIANEERKEAPHAPILPPTLPIPHAIRDHLDEYVI
GQDRAKKVMAVAVYNHYKRLRAQAQGDTDVEIQKSNILLVGPTGSGKTLLAQTLARMLDVPFAIADATALTEAGYVGEDV
ETILLRLIQAADGDVDRAQMGILYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVVNVPPMPGRKHPQQEFIPF
DTTNVLFICGGAFEGLEHHIAERMGSGGTLGFGKTIVKEERLERSKKLLSLVNPDDLLHFGFIPEFIGRMPVVAALTPLD
KDAMMRILTEPRNAIIKQYQKMLALDHVQLEVSGDAMEAIVERALAGKTGARGLRTAVEEILLDVMFDLPSETDVVRCVI
TAETVRDGAMPTLIRRTSSRSRAGKQPTTKAS

Sequences:

>Translated_432_residues
MAQSAFMPPTYYCSFCGRNQDEVDRLVTGPGALFICNECIELLSAIIANEERKEAPHAPILPPTLPIPHAIRDHLDEYVI
GQDRAKKVMAVAVYNHYKRLRAQAQGDTDVEIQKSNILLVGPTGSGKTLLAQTLARMLDVPFAIADATALTEAGYVGEDV
ETILLRLIQAADGDVDRAQMGILYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVVNVPPMPGRKHPQQEFIPF
DTTNVLFICGGAFEGLEHHIAERMGSGGTLGFGKTIVKEERLERSKKLLSLVNPDDLLHFGFIPEFIGRMPVVAALTPLD
KDAMMRILTEPRNAIIKQYQKMLALDHVQLEVSGDAMEAIVERALAGKTGARGLRTAVEEILLDVMFDLPSETDVVRCVI
TAETVRDGAMPTLIRRTSSRSRAGKQPTTKAS
>Mature_431_residues
AQSAFMPPTYYCSFCGRNQDEVDRLVTGPGALFICNECIELLSAIIANEERKEAPHAPILPPTLPIPHAIRDHLDEYVIG
QDRAKKVMAVAVYNHYKRLRAQAQGDTDVEIQKSNILLVGPTGSGKTLLAQTLARMLDVPFAIADATALTEAGYVGEDVE
TILLRLIQAADGDVDRAQMGILYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVVNVPPMPGRKHPQQEFIPFD
TTNVLFICGGAFEGLEHHIAERMGSGGTLGFGKTIVKEERLERSKKLLSLVNPDDLLHFGFIPEFIGRMPVVAALTPLDK
DAMMRILTEPRNAIIKQYQKMLALDHVQLEVSGDAMEAIVERALAGKTGARGLRTAVEEILLDVMFDLPSETDVVRCVIT
AETVRDGAMPTLIRRTSSRSRAGKQPTTKAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=335, Percent_Identity=47.1641791044776, Blast_Score=288, Evalue=6e-78,
Organism=Escherichia coli, GI1786642, Length=405, Percent_Identity=59.2592592592593, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=42.3076923076923, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982905, Length=316, Percent_Identity=42.7215189873418, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71982908, Length=316, Percent_Identity=42.7215189873418, Blast_Score=260, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=414, Percent_Identity=37.1980676328502, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=248, Percent_Identity=40.3225806451613, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=39.2018779342723, Blast_Score=270, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24648291, Length=323, Percent_Identity=46.749226006192, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24648289, Length=323, Percent_Identity=46.749226006192, Blast_Score=279, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_HERA2 (A9B8B2)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546593.1
- ProteinModelPortal:   A9B8B2
- GeneID:   5735693
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3829
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   HAUR316274:HAUR_3829-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 47228; Mature: 47097

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSAFMPPTYYCSFCGRNQDEVDRLVTGPGALFICNECIELLSAIIANEERKEAPHAPI
CCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
LPPTLPIPHAIRDHLDEYVIGQDRAKKVMAVAVYNHYKRLRAQAQGDTDVEIQKSNILLV
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEE
GPTGSGKTLLAQTLARMLDVPFAIADATALTEAGYVGEDVETILLRLIQAADGDVDRAQM
ECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHC
GILYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVVNVPPMPGRKHPQQEFIPF
CEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCHHCCCCC
DTTNVLFICGGAFEGLEHHIAERMGSGGTLGFGKTIVKEERLERSKKLLSLVNPDDLLHF
CCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
GFIPEFIGRMPVVAALTPLDKDAMMRILTEPRNAIIKQYQKMLALDHVQLEVSGDAMEAI
CCHHHHHCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEECCHHHHHH
VERALAGKTGARGLRTAVEEILLDVMFDLPSETDVVRCVITAETVRDGAMPTLIRRTSSR
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHCHH
SRAGKQPTTKAS
HHCCCCCCCCCC
>Mature Secondary Structure 
AQSAFMPPTYYCSFCGRNQDEVDRLVTGPGALFICNECIELLSAIIANEERKEAPHAPI
CCCCCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
LPPTLPIPHAIRDHLDEYVIGQDRAKKVMAVAVYNHYKRLRAQAQGDTDVEIQKSNILLV
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEE
GPTGSGKTLLAQTLARMLDVPFAIADATALTEAGYVGEDVETILLRLIQAADGDVDRAQM
ECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHC
GILYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVVNVPPMPGRKHPQQEFIPF
CEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCHHCCCCC
DTTNVLFICGGAFEGLEHHIAERMGSGGTLGFGKTIVKEERLERSKKLLSLVNPDDLLHF
CCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
GFIPEFIGRMPVVAALTPLDKDAMMRILTEPRNAIIKQYQKMLALDHVQLEVSGDAMEAI
CCHHHHHCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEECCHHHHHH
VERALAGKTGARGLRTAVEEILLDVMFDLPSETDVVRCVITAETVRDGAMPTLIRRTSSR
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHCHH
SRAGKQPTTKAS
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA