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The map label for this gene is clpP [H]

Identifier: 159900345

GI number: 159900345

Start: 4807057

End: 4807713

Strand: Direct

Name: clpP [H]

Synonym: Haur_3828

Alternate gene names: 159900345

Gene position: 4807057-4807713 (Clockwise)

Preceding gene: 159900344

Following gene: 159900346

Centisome position: 75.74

GC content: 48.86

Gene sequence:

>657_bases
ATGTCCTGGTTTCAATGGCTCTCACCTGCTCACGACATTGTGGCAGCGAAATCGCCCTCAATGGTTGTTCCCTACGTTGT
AGAAACAAGCAGCCGTGGCGAACGAGTTTATGACATCTACTCACGTTTGCTCAAAGAGCGGATCATCATTCTCGGTACGC
CGATTGATTCGCAAATTGCGAATGTGTTGGTGGCTCAATTATTGTTCTTGCAACACGATGACCCTGATCGCGATATTTCA
ATCTATATCAACAGCCCAGGCGGCGAAGTGAATGCTGGCCTTGCGATCTACGATACGATGCAGATGGTTTCGCCCGATAT
TGCGACCTGGTGTGTTGGTTTTGCTGGCAGTATGGCAACGCCAGTTCTGGCTGGTGGTACCAAAGGCAAGCGCTATTCAT
TGCCCAATTCAACCATCCACATGCACCCAGCTGGTGGTGGTGCTCGCGGTTATGCGCCTGATGTCGAAATTCAAATTAAA
GAGTTGTTGCGCTTGCAAAACATTGTGCGTGGCTTGCTGGCAAAAGATACTGGTCAGCCGATCGAGCGGATTGCCCGCGA
CTTCGACCGTGATTTGTTTATGACACCAGAACAAGCCAAAGAATATGGTATCATTGACGAAATTACGACCCACATTGAAG
CTGGGCAACAAGATTAA

Upstream 100 bases:

>100_bases
GATGCAATGGAATGGCCCTCTGCCATGCGCGAGGTTTTTCGGGTAGACTAGAAGCATCGACCGAAGTGCGCCGATGCGCA
CCGTTGCAAGGAGGCTTGCT

Downstream 100 bases:

>100_bases
TTGAGCAACAAGGATGATGACGCGAGCCTCGTTGCTCGCGTCGTCACCAATGGGAGCAATTCCAATGGCGCAATCCGCCT
TTATGCCACCGACCTACTAC

Product: endopeptidase Clp

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSWFQWLSPAHDIVAAKSPSMVVPYVVETSSRGERVYDIYSRLLKERIIILGTPIDSQIANVLVAQLLFLQHDDPDRDIS
IYINSPGGEVNAGLAIYDTMQMVSPDIATWCVGFAGSMATPVLAGGTKGKRYSLPNSTIHMHPAGGGARGYAPDVEIQIK
ELLRLQNIVRGLLAKDTGQPIERIARDFDRDLFMTPEQAKEYGIIDEITTHIEAGQQD

Sequences:

>Translated_218_residues
MSWFQWLSPAHDIVAAKSPSMVVPYVVETSSRGERVYDIYSRLLKERIIILGTPIDSQIANVLVAQLLFLQHDDPDRDIS
IYINSPGGEVNAGLAIYDTMQMVSPDIATWCVGFAGSMATPVLAGGTKGKRYSLPNSTIHMHPAGGGARGYAPDVEIQIK
ELLRLQNIVRGLLAKDTGQPIERIARDFDRDLFMTPEQAKEYGIIDEITTHIEAGQQD
>Mature_217_residues
SWFQWLSPAHDIVAAKSPSMVVPYVVETSSRGERVYDIYSRLLKERIIILGTPIDSQIANVLVAQLLFLQHDDPDRDISI
YINSPGGEVNAGLAIYDTMQMVSPDIATWCVGFAGSMATPVLAGGTKGKRYSLPNSTIHMHPAGGGARGYAPDVEIQIKE
LLRLQNIVRGLLAKDTGQPIERIARDFDRDLFMTPEQAKEYGIIDEITTHIEAGQQD

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=190, Percent_Identity=51.0526315789474, Blast_Score=205, Evalue=2e-53,
Organism=Escherichia coli, GI1786641, Length=195, Percent_Identity=49.7435897435897, Blast_Score=213, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI17538017, Length=189, Percent_Identity=47.0899470899471, Blast_Score=193, Evalue=5e-50,
Organism=Drosophila melanogaster, GI20129427, Length=190, Percent_Identity=51.5789473684211, Blast_Score=198, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 24040; Mature: 23909

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWFQWLSPAHDIVAAKSPSMVVPYVVETSSRGERVYDIYSRLLKERIIILGTPIDSQIA
CCHHHHCCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCHHHHH
NVLVAQLLFLQHDDPDRDISIYINSPGGEVNAGLAIYDTMQMVSPDIATWCVGFAGSMAT
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCHHHC
PVLAGGTKGKRYSLPNSTIHMHPAGGGARGYAPDVEIQIKELLRLQNIVRGLLAKDTGQP
CEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
IERIARDFDRDLFMTPEQAKEYGIIDEITTHIEAGQQD
HHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SWFQWLSPAHDIVAAKSPSMVVPYVVETSSRGERVYDIYSRLLKERIIILGTPIDSQIA
CHHHHCCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCEEEEECCCHHHHH
NVLVAQLLFLQHDDPDRDISIYINSPGGEVNAGLAIYDTMQMVSPDIATWCVGFAGSMAT
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCHHHC
PVLAGGTKGKRYSLPNSTIHMHPAGGGARGYAPDVEIQIKELLRLQNIVRGLLAKDTGQP
CEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
IERIARDFDRDLFMTPEQAKEYGIIDEITTHIEAGQQD
HHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA