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The map label for this gene is purQ [H]

Identifier: 159900286

GI number: 159900286

Start: 4737759

End: 4738529

Strand: Reverse

Name: purQ [H]

Synonym: Haur_3769

Alternate gene names: 159900286

Gene position: 4738529-4737759 (Counterclockwise)

Preceding gene: 159900287

Following gene: 159900283

Centisome position: 74.66

GC content: 54.09

Gene sequence:

>771_bases
ATGACAAAGGTATTGGTGCTTCGCGCACCGGGGATTAACTGTGATGCCGAGGCCGCCGAAGCCCTCGAATTAGCGGGAGC
CAAGGCTGAGCGGGTTCACGTTAACCGTTTGGCCGAAGGCAGCGTTCAATTGGCCGATTATGGCATGCTGCTGATTCCAG
GCGGCTTTGCTTATGGCGACCATCTTGGTGCAGGCCGCATGTTGGCAGTCGATTTGATCTATCGTTTGCGCGAGGATCTG
AGCCGCTTTGTGGCTGATGGTCGGCCTGTGCTGGGCATTTGCAATGGTTTTCAGGTTTTGGTCAAAACTGGGCTTTTGCC
CAGCGATAAAGTAGGCCAAGCCACCTTGATCGATAACGCTAGCGGCCATTACGAGTGTCGCTGGATCAAATTGGGCCTCA
ACAGTGCTAGCCCATGTCTCTTTACCCAAGGCTTGAGTGGCACGCTCGATTTGCCGGTTGGCCATGGCGAAGGCCGTTTC
CTAACCGATCAAGCTACGCTCGAAAAGCTCCAAGCCAATAACCAAATTGTGGTGCAATATCTTGATCAAGCCGACCAACC
AACCATGGACTATCCGGCTAATCCTAACGGAGCTTTAAATGCAATCGCGGGTATTTGTAACCCAGCGGGCAATGTGTTTG
GCTTGATGCCGCACCCTGATCGAGCCTTCTTGCCGCAACATCATCCACAATGGCGGCGACGCGGCCTTGACCTCGAAGGA
CCAGGCATGGCGATTTTCCGCAACGGCGTGCGAGCAATGGCCTTAGTTTAA

Upstream 100 bases:

>100_bases
CATGCTTCGCGCCAGCAACATGTGATTGAACGATGACAGAACATAGAGCATAGAACATAAACATTTGAATAATCGACCTT
CACGATAAGGAACTTTGATT

Downstream 100 bases:

>100_bases
GCCCAATGGCGCAACAGCAAAAATCTGTTGCGCCATGTTCAATTTCAATCAACGTGCTAGAGCGTTGCTACTTGATTACG
TGGTGAACCACCCCAATTGT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTKVLVLRAPGINCDAEAAEALELAGAKAERVHVNRLAEGSVQLADYGMLLIPGGFAYGDHLGAGRMLAVDLIYRLREDL
SRFVADGRPVLGICNGFQVLVKTGLLPSDKVGQATLIDNASGHYECRWIKLGLNSASPCLFTQGLSGTLDLPVGHGEGRF
LTDQATLEKLQANNQIVVQYLDQADQPTMDYPANPNGALNAIAGICNPAGNVFGLMPHPDRAFLPQHHPQWRRRGLDLEG
PGMAIFRNGVRAMALV

Sequences:

>Translated_256_residues
MTKVLVLRAPGINCDAEAAEALELAGAKAERVHVNRLAEGSVQLADYGMLLIPGGFAYGDHLGAGRMLAVDLIYRLREDL
SRFVADGRPVLGICNGFQVLVKTGLLPSDKVGQATLIDNASGHYECRWIKLGLNSASPCLFTQGLSGTLDLPVGHGEGRF
LTDQATLEKLQANNQIVVQYLDQADQPTMDYPANPNGALNAIAGICNPAGNVFGLMPHPDRAFLPQHHPQWRRRGLDLEG
PGMAIFRNGVRAMALV
>Mature_255_residues
TKVLVLRAPGINCDAEAAEALELAGAKAERVHVNRLAEGSVQLADYGMLLIPGGFAYGDHLGAGRMLAVDLIYRLREDLS
RFVADGRPVLGICNGFQVLVKTGLLPSDKVGQATLIDNASGHYECRWIKLGLNSASPCLFTQGLSGTLDLPVGHGEGRFL
TDQATLEKLQANNQIVVQYLDQADQPTMDYPANPNGALNAIAGICNPAGNVFGLMPHPDRAFLPQHHPQWRRRGLDLEGP
GMAIFRNGVRAMALV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=270, Percent_Identity=32.5925925925926, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI48994899, Length=259, Percent_Identity=35.5212355212355, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17553022, Length=271, Percent_Identity=28.4132841328413, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321498, Length=265, Percent_Identity=32.8301886792453, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24582111, Length=230, Percent_Identity=35.2173913043478, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24582109, Length=230, Percent_Identity=35.2173913043478, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17137292, Length=230, Percent_Identity=35.2173913043478, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 27503; Mature: 27372

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLVLRAPGINCDAEAAEALELAGAKAERVHVNRLAEGSVQLADYGMLLIPGGFAYGD
CCEEEEEECCCCCCCHHHHHHHHHCCCCHHEEEHHHHCCCCEEEECCCEEEECCCCCCCC
HLGAGRMLAVDLIYRLREDLSRFVADGRPVLGICNGFQVLVKTGLLPSDKVGQATLIDNA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCCCEEEEECC
SGHYECRWIKLGLNSASPCLFTQGLSGTLDLPVGHGEGRFLTDQATLEKLQANNQIVVQY
CCCEEEEEEEEECCCCCCEEEECCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCEEEEEE
LDQADQPTMDYPANPNGALNAIAGICNPAGNVFGLMPHPDRAFLPQHHPQWRRRGLDLEG
HHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCCC
PGMAIFRNGVRAMALV
CCHHHHHCCCEEEEEC
>Mature Secondary Structure 
TKVLVLRAPGINCDAEAAEALELAGAKAERVHVNRLAEGSVQLADYGMLLIPGGFAYGD
CEEEEEECCCCCCCHHHHHHHHHCCCCHHEEEHHHHCCCCEEEECCCEEEECCCCCCCC
HLGAGRMLAVDLIYRLREDLSRFVADGRPVLGICNGFQVLVKTGLLPSDKVGQATLIDNA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCCCEEEEECC
SGHYECRWIKLGLNSASPCLFTQGLSGTLDLPVGHGEGRFLTDQATLEKLQANNQIVVQY
CCCEEEEEEEEECCCCCCEEEECCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCEEEEEE
LDQADQPTMDYPANPNGALNAIAGICNPAGNVFGLMPHPDRAFLPQHHPQWRRRGLDLEG
HHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHCCCCCCC
PGMAIFRNGVRAMALV
CCHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA