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The map label for this gene is engA

Identifier: 159900085

GI number: 159900085

Start: 4485763

End: 4487130

Strand: Reverse

Name: engA

Synonym: Haur_3568

Alternate gene names: 159900085

Gene position: 4487130-4485763 (Counterclockwise)

Preceding gene: 159900086

Following gene: 159900079

Centisome position: 70.7

GC content: 50.29

Gene sequence:

>1368_bases
ATGGAAAAACCAATTGTGGCGATTGTTGGCCGACCTAACGTTGGCAAATCGACCTTGTTTAATAAGCTGATTGGCGAGCG
CCGCGCGATTATTGCCGATGAAGCTGGTACAACCCGCGACCGCCAATATGGCGAAACCATCTGGAATGGCCGCGTATTTA
CGATTGTGGATACAGCTGGGTTGTTGGTTGGCGATGATGACCCGAACTTGCCTTTGGCTGAAATTGTGCGCCGTACTCAC
CAACAAGCTCAATTGGCGATCGATGAAGCCGATGTGATTGTGTTTATGGTCGATGTGCGTGAAGGACTGATTGCTGCTGA
TGAAGAGGTTGCCGCCTTGTTACGTCGCAGCAGCAAGCCCGTGGTCTTGGGTGTAAACAAAGCCGATACCGAAGATCGCC
GCCAGAATGCGGTCGAATTCTATAACCTTGGCTTGGGCGACCCAATTGCCTTGAGCGCTTACCATGGCACTGGCTCGGGC
GATTTGCTCGATGAAATTGTACGCCACTTGCCAGCAGGCCAAGAAGAAGAGGAAGACGACAATTCGCTGAAAATTGCGAT
TGTCGGGCGACCAAACGTTGGTAAATCGAGCTTGCTGAATAAATTGGTCGGCGAAGAGCGGGTGGTTGTCAGCAATATTC
CTGGCACAACTCGCGATTCAATCGACACCAAATTGACCTATAAAGGCATTCCAATCACCTTGATCGACACCGCTGGGATT
CGGCGGCGTGGCTCGATTGAGCAAGGGATTGAACGCTACAGCGTGTTACGCACGATGAAAGCGATCGAGCGTTGCCATAT
TGCCTTGATTTTGGTCGATGCCCAAGAAGGCCCAACCGCTCAAGATACCCACGTCGCAGGTATGGTTTTGGAAGCTAACA
AAGGCTTGGCGATTATCGTCAACAAATGGGATTTGATCGATAAAGCCAAATTCAGCTACGAAGATGCCAAAACTACGATG
TCGCAGGTGTTTCACTTTGCGCCGTATGCGCCGATTGAATTTATTTCGGCAAAAACTGGCCAACGGGCTACTAAAGTGCT
CGATATTGCCCAAACAATCCAGAGCGAACGCAACAAACGCGTAAGCACCTCGGATATTAACAACTTGTTGCGGGCGGCGG
TGCGCGAACATCCACCAACAGCGATGCATAAAGGCGCTCACTTGCGCTTATTCTATGCAACTCAAGCCCAAGTCGAGCCA
CCAGTGTTCCTGTTCTTCTCGAATGCGCCAGAACAAGTGCACTTTGGCTACAAGCGCTACCTCGAAAATCGTATTCGCGA
ACAATATGGTTTTATTGGCACACCAATTATTTTGGTGTTCAAAGGCCGCGAAGAAGAGCAAACCGTCTCGGTTTCCGGTA
AGCGCTAA

Upstream 100 bases:

>100_bases
CAATCGCTGTATTGGGTCAAACGGCCACGATTGTGCAACTTGAACGTCGTAGAATGTAGTGATGTTGGCTTTTGGGCCGC
ATTGCGAAAGAGGTATAACC

Downstream 100 bases:

>100_bases
ATATTCTAGCATTCAATTAAAAAGCACTTCAATCAATTACGATTGAGGTGCTTTTTACGATTAACTATTTAATGATTAAT
TCCAGCGAATTAGGCTAATT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MEKPIVAIVGRPNVGKSTLFNKLIGERRAIIADEAGTTRDRQYGETIWNGRVFTIVDTAGLLVGDDDPNLPLAEIVRRTH
QQAQLAIDEADVIVFMVDVREGLIAADEEVAALLRRSSKPVVLGVNKADTEDRRQNAVEFYNLGLGDPIALSAYHGTGSG
DLLDEIVRHLPAGQEEEEDDNSLKIAIVGRPNVGKSSLLNKLVGEERVVVSNIPGTTRDSIDTKLTYKGIPITLIDTAGI
RRRGSIEQGIERYSVLRTMKAIERCHIALILVDAQEGPTAQDTHVAGMVLEANKGLAIIVNKWDLIDKAKFSYEDAKTTM
SQVFHFAPYAPIEFISAKTGQRATKVLDIAQTIQSERNKRVSTSDINNLLRAAVREHPPTAMHKGAHLRLFYATQAQVEP
PVFLFFSNAPEQVHFGYKRYLENRIREQYGFIGTPIILVFKGREEEQTVSVSGKR

Sequences:

>Translated_455_residues
MEKPIVAIVGRPNVGKSTLFNKLIGERRAIIADEAGTTRDRQYGETIWNGRVFTIVDTAGLLVGDDDPNLPLAEIVRRTH
QQAQLAIDEADVIVFMVDVREGLIAADEEVAALLRRSSKPVVLGVNKADTEDRRQNAVEFYNLGLGDPIALSAYHGTGSG
DLLDEIVRHLPAGQEEEEDDNSLKIAIVGRPNVGKSSLLNKLVGEERVVVSNIPGTTRDSIDTKLTYKGIPITLIDTAGI
RRRGSIEQGIERYSVLRTMKAIERCHIALILVDAQEGPTAQDTHVAGMVLEANKGLAIIVNKWDLIDKAKFSYEDAKTTM
SQVFHFAPYAPIEFISAKTGQRATKVLDIAQTIQSERNKRVSTSDINNLLRAAVREHPPTAMHKGAHLRLFYATQAQVEP
PVFLFFSNAPEQVHFGYKRYLENRIREQYGFIGTPIILVFKGREEEQTVSVSGKR
>Mature_455_residues
MEKPIVAIVGRPNVGKSTLFNKLIGERRAIIADEAGTTRDRQYGETIWNGRVFTIVDTAGLLVGDDDPNLPLAEIVRRTH
QQAQLAIDEADVIVFMVDVREGLIAADEEVAALLRRSSKPVVLGVNKADTEDRRQNAVEFYNLGLGDPIALSAYHGTGSG
DLLDEIVRHLPAGQEEEEDDNSLKIAIVGRPNVGKSSLLNKLVGEERVVVSNIPGTTRDSIDTKLTYKGIPITLIDTAGI
RRRGSIEQGIERYSVLRTMKAIERCHIALILVDAQEGPTAQDTHVAGMVLEANKGLAIIVNKWDLIDKAKFSYEDAKTTM
SQVFHFAPYAPIEFISAKTGQRATKVLDIAQTIQSERNKRVSTSDINNLLRAAVREHPPTAMHKGAHLRLFYATQAQVEP
PVFLFFSNAPEQVHFGYKRYLENRIREQYGFIGTPIILVFKGREEEQTVSVSGKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=39.5299145299145, Blast_Score=318, Evalue=5e-88,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=42.3913043478261, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788919, Length=183, Percent_Identity=31.6939890710383, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=115, Percent_Identity=39.1304347826087, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323665, Length=149, Percent_Identity=36.241610738255, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45550813, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_HERA2 (A9B567)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001546332.1
- ProteinModelPortal:   A9B567
- SMR:   A9B567
- GeneID:   5735427
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_3568
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   HAUR316274:HAUR_3568-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50384; Mature: 50384

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPIVAIVGRPNVGKSTLFNKLIGERRAIIADEAGTTRDRQYGETIWNGRVFTIVDTAG
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCEEEEEEECCC
LLVGDDDPNLPLAEIVRRTHQQAQLAIDEADVIVFMVDVREGLIAADEEVAALLRRSSKP
EEECCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCC
VVLGVNKADTEDRRQNAVEFYNLGLGDPIALSAYHGTGSGDLLDEIVRHLPAGQEEEEDD
EEEECCCCCCHHHHHCCHHEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
NSLKIAIVGRPNVGKSSLLNKLVGEERVVVSNIPGTTRDSIDTKLTYKGIPITLIDTAGI
CCEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCC
RRRGSIEQGIERYSVLRTMKAIERCHIALILVDAQEGPTAQDTHVAGMVLEANKGLAIIV
CCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEE
NKWDLIDKAKFSYEDAKTTMSQVFHFAPYAPIEFISAKTGQRATKVLDIAQTIQSERNKR
ECCCCHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
VSTSDINNLLRAAVREHPPTAMHKGAHLRLFYATQAQVEPPVFLFFSNAPEQVHFGYKRY
CCHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHH
LENRIREQYGFIGTPIILVFKGREEEQTVSVSGKR
HHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCC
>Mature Secondary Structure
MEKPIVAIVGRPNVGKSTLFNKLIGERRAIIADEAGTTRDRQYGETIWNGRVFTIVDTAG
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCEEEEEEECCC
LLVGDDDPNLPLAEIVRRTHQQAQLAIDEADVIVFMVDVREGLIAADEEVAALLRRSSKP
EEECCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCC
VVLGVNKADTEDRRQNAVEFYNLGLGDPIALSAYHGTGSGDLLDEIVRHLPAGQEEEEDD
EEEECCCCCCHHHHHCCHHEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
NSLKIAIVGRPNVGKSSLLNKLVGEERVVVSNIPGTTRDSIDTKLTYKGIPITLIDTAGI
CCEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCC
RRRGSIEQGIERYSVLRTMKAIERCHIALILVDAQEGPTAQDTHVAGMVLEANKGLAIIV
CCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEE
NKWDLIDKAKFSYEDAKTTMSQVFHFAPYAPIEFISAKTGQRATKVLDIAQTIQSERNKR
ECCCCHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
VSTSDINNLLRAAVREHPPTAMHKGAHLRLFYATQAQVEPPVFLFFSNAPEQVHFGYKRY
CCHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHH
LENRIREQYGFIGTPIILVFKGREEEQTVSVSGKR
HHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA