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The map label for this gene is appB [H]

Identifier: 159900017

GI number: 159900017

Start: 4407864

End: 4408931

Strand: Reverse

Name: appB [H]

Synonym: Haur_3500

Alternate gene names: 159900017

Gene position: 4408931-4407864 (Counterclockwise)

Preceding gene: 159900018

Following gene: 159900016

Centisome position: 69.47

GC content: 48.69

Gene sequence:

>1068_bases
ATGACCGTATATCTCATTCGGCGCTTGTTCCAAGCGATTCTCGTCCTTATTTTATCGTCAGCAGTGATTTACTCGCTGTT
TGCCCTGGCTCCTGGTGGCCCACTTGAGGAGCTAACCCAAGTTACCGACCCCAAGAATCGGCCTAGCCCCGAAGATATTC
AACGTCAAATCAAGTTGCTAGGGGCCGATAAGCCTTGGTTCTTGTGGTATCCAACTTGGCTCGCTGGTGATACCTGGATG
GATAAAATTGGGTTTGAAGAATATCAGGGCGAACGCAAGGGGATCTTGCGCTGGGATTGGGGTACATCGTGGAAGTTTCA
ACGTAATAAGCCAGTCTTGGAGATTATTGGCGATAAATTGCCCGATACCCTGTGGTTGATGATTTCATCAACAATTATTT
CGTTGGTGCTGGGCATTCCGCTGGGGGTTTTCTCAGCAGTGCGCCAATATTCTTTTTTTGATTATGTGTTGACCACATTT
AGCTTTATTGGCTTATCACTGCCGGCCTTCTGGTTTGGTTTGTTGATTATCGCGGTATCGCTGTGGTTTAAACGCAATGG
CTGGTTCTACTTCCCCGCTGGCGATATTCTGGCCCTGCGTAATTACGAGGTTCCGATTCTTGGCACGGTCGTCGCTGGCT
CGTTGCTTGATCGGGTGATGCACTTGGTTATGCCTGTTACGGTGCTTTCAATGCTCAACTTGGCCAACTGGAGCCGCTTT
ATGCGGGCGAGTATGCTTGAAGTGTTGAGCCAAGATTATGTGCGGACTGCCCGCGCTAAAGGGGTCAAAGAACGCGTCGT
GATCTACAAGCATGCCTTCCGCAATGCCTTGATTCCATTGATCACGATCATCGTCTTTGCGATTCCTGGGGTGTTTGGTG
GCGCACTGTTTACCGAAACAGTCTTTAATTATAAAGCGCTCGGCTTTACCTTTATTAGCGCTCTGAACCTCAAAGATTAT
CCTTTGGCGATGGCCTTCTTGCTGATTTCGTCGATCTTGTTGGTGTTTGCGACGTTGCTGGCGGATGTGCTCTATACCAT
TGTTGACCCACGAATTCGACTTGACTAG

Upstream 100 bases:

>100_bases
TGATTGCTCTTTTTTTGAACGTAATTTGCCAAAGTAGAGTGTAGTAGTTAACAACTGTTTATCTTGGCATTAACCATTCA
AGCAAGTGTAGAGGTACCGC

Downstream 100 bases:

>100_bases
TTGCTACTGGTAGGGTGCGATTGGTTTCATTAACCTTGTGAAAGGAAGATCCATGGCTGTTTCAACAACGCAAGTCGAAG
CTCATGAGCCTAAAAAAGAA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTVYLIRRLFQAILVLILSSAVIYSLFALAPGGPLEELTQVTDPKNRPSPEDIQRQIKLLGADKPWFLWYPTWLAGDTWM
DKIGFEEYQGERKGILRWDWGTSWKFQRNKPVLEIIGDKLPDTLWLMISSTIISLVLGIPLGVFSAVRQYSFFDYVLTTF
SFIGLSLPAFWFGLLIIAVSLWFKRNGWFYFPAGDILALRNYEVPILGTVVAGSLLDRVMHLVMPVTVLSMLNLANWSRF
MRASMLEVLSQDYVRTARAKGVKERVVIYKHAFRNALIPLITIIVFAIPGVFGGALFTETVFNYKALGFTFISALNLKDY
PLAMAFLLISSILLVFATLLADVLYTIVDPRIRLD

Sequences:

>Translated_355_residues
MTVYLIRRLFQAILVLILSSAVIYSLFALAPGGPLEELTQVTDPKNRPSPEDIQRQIKLLGADKPWFLWYPTWLAGDTWM
DKIGFEEYQGERKGILRWDWGTSWKFQRNKPVLEIIGDKLPDTLWLMISSTIISLVLGIPLGVFSAVRQYSFFDYVLTTF
SFIGLSLPAFWFGLLIIAVSLWFKRNGWFYFPAGDILALRNYEVPILGTVVAGSLLDRVMHLVMPVTVLSMLNLANWSRF
MRASMLEVLSQDYVRTARAKGVKERVVIYKHAFRNALIPLITIIVFAIPGVFGGALFTETVFNYKALGFTFISALNLKDY
PLAMAFLLISSILLVFATLLADVLYTIVDPRIRLD
>Mature_354_residues
TVYLIRRLFQAILVLILSSAVIYSLFALAPGGPLEELTQVTDPKNRPSPEDIQRQIKLLGADKPWFLWYPTWLAGDTWMD
KIGFEEYQGERKGILRWDWGTSWKFQRNKPVLEIIGDKLPDTLWLMISSTIISLVLGIPLGVFSAVRQYSFFDYVLTTFS
FIGLSLPAFWFGLLIIAVSLWFKRNGWFYFPAGDILALRNYEVPILGTVVAGSLLDRVMHLVMPVTVLSMLNLANWSRFM
RASMLEVLSQDYVRTARAKGVKERVVIYKHAFRNALIPLITIIVFAIPGVFGGALFTETVFNYKALGFTFISALNLKDYP
LAMAFLLISSILLVFATLLADVLYTIVDPRIRLD

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=366, Percent_Identity=32.2404371584699, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1787053, Length=353, Percent_Identity=30.3116147308782, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1789888, Length=354, Percent_Identity=27.9661016949153, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1788504, Length=378, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787497, Length=357, Percent_Identity=24.6498599439776, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787761, Length=363, Percent_Identity=29.7520661157025, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=27.007299270073, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40353; Mature: 40222

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYLIRRLFQAILVLILSSAVIYSLFALAPGGPLEELTQVTDPKNRPSPEDIQRQIKLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHH
GADKPWFLWYPTWLAGDTWMDKIGFEEYQGERKGILRWDWGTSWKFQRNKPVLEIIGDKL
CCCCCEEEEECHHHCCCHHHHHCCHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCC
PDTLWLMISSTIISLVLGIPLGVFSAVRQYSFFDYVLTTFSFIGLSLPAFWFGLLIIAVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWFKRNGWFYFPAGDILALRNYEVPILGTVVAGSLLDRVMHLVMPVTVLSMLNLANWSRF
HHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRASMLEVLSQDYVRTARAKGVKERVVIYKHAFRNALIPLITIIVFAIPGVFGGALFTET
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNYKALGFTFISALNLKDYPLAMAFLLISSILLVFATLLADVLYTIVDPRIRLD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVYLIRRLFQAILVLILSSAVIYSLFALAPGGPLEELTQVTDPKNRPSPEDIQRQIKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHH
GADKPWFLWYPTWLAGDTWMDKIGFEEYQGERKGILRWDWGTSWKFQRNKPVLEIIGDKL
CCCCCEEEEECHHHCCCHHHHHCCHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCC
PDTLWLMISSTIISLVLGIPLGVFSAVRQYSFFDYVLTTFSFIGLSLPAFWFGLLIIAVS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWFKRNGWFYFPAGDILALRNYEVPILGTVVAGSLLDRVMHLVMPVTVLSMLNLANWSRF
HHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRASMLEVLSQDYVRTARAKGVKERVVIYKHAFRNALIPLITIIVFAIPGVFGGALFTET
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNYKALGFTFISALNLKDYPLAMAFLLISSILLVFATLLADVLYTIVDPRIRLD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]