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The map label for this gene is glpX [H]

Identifier: 159899895

GI number: 159899895

Start: 4258333

End: 4259319

Strand: Reverse

Name: glpX [H]

Synonym: Haur_3378

Alternate gene names: 159899895

Gene position: 4259319-4258333 (Counterclockwise)

Preceding gene: 159899896

Following gene: 159899894

Centisome position: 67.11

GC content: 53.9

Gene sequence:

>987_bases
ATGAAGCTGGAGCGTAATTTGGGGTTTGATCTCCAACGGGCAACCGAAGCGGCTGCGTTACGTTCAGCCCGCTGGATGGG
TCGGGGCGATAAGAACGAAGCTGATGGTGCGGCGGTCGATGCGATGCGGTTTGCCCTCAATGCCACCGATATGGATGGAA
TTGTGGTGATCGGTGAAGGCGAAAAAGACGAAGCACCCATGCTCTACATTGGCGAGCAGATCGGCAACGGCAGCGAACCA
CGGGTTGATATTGCGGTTGATCCAGTTGAAGGCACGACCTTGCTAGCCCAGGGCATGCCGGGGGCAATTGCGGTCGTCGC
AGCAGCCGAACGTGGCAGTCTATTCAACCCACCAGGGATCGTCTACATGGATAAAATTGCCGTTGGCGAATCAGCCAAGG
GCAGTATCGATATCAACGCTTCGGTTGAAGACAACATCCGCAGCGTTGCCAAAGCACTTAAAAAACGGGTCGAAGATGTA
ACGGTCATTGTGCTTGATCGGCCTCGCCATCACGATGTTATTGCGCGGATTCGTGAAATGGGAGCGCGGATTAAACTGAT
TTTGCATGGTGACGTTGCAGCCAGCCTCATGCCGAGCATGCTTGAGGCTCCCGCAGATATTCTCATGGGCATTGGCGGAG
CACCCGAGTCGGTGATTTCGGCCTGCGCCATGAAGTGTACTGGTGGCGAGATTCAGTGTAAGCTCTGGCCGCGTAATGAC
CGTGAGCGTGACCTAGCCCGTCAGAACGGCTTGAATCTCGACAAAGTGTACACGACCAACGATTTGGTACAAGGAGACAA
TATTTTTTGGGCGGCGACGGGAATTACGACCGGAGATTTTCTCAAGGGCGTACAATTTTTTGGGTGGGGTGCTACCACTC
ACTCGTTAGTCATGCGTTCGGCCTCTGGCACAGTACGCTACATCGAGTCTCGTCACCGTTGGGATAAATTGATGCGGATT
TCAGATTTGCCGTTTGCCGAGCACTAA

Upstream 100 bases:

>100_bases
ATCATCATTTGCTGCCGACTTTGCGAAATATGGTACAATCGCATTTTTAGAATACTCGTAAAGCTCGCAAGCGATGATAT
TGCACAACAAGGAGGTTGGC

Downstream 100 bases:

>100_bases
ATATACCGTCACTGTTTGCGTTAGAAATTGCTTAAAATCGAGCAACGTCATGCTAAAAAATGGCGTTGCTTGCTTTTGTC
AGTCGTGGTATACTGCGTGC

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKLERNLGFDLQRATEAAALRSARWMGRGDKNEADGAAVDAMRFALNATDMDGIVVIGEGEKDEAPMLYIGEQIGNGSEP
RVDIAVDPVEGTTLLAQGMPGAIAVVAAAERGSLFNPPGIVYMDKIAVGESAKGSIDINASVEDNIRSVAKALKKRVEDV
TVIVLDRPRHHDVIARIREMGARIKLILHGDVAASLMPSMLEAPADILMGIGGAPESVISACAMKCTGGEIQCKLWPRND
RERDLARQNGLNLDKVYTTNDLVQGDNIFWAATGITTGDFLKGVQFFGWGATTHSLVMRSASGTVRYIESRHRWDKLMRI
SDLPFAEH

Sequences:

>Translated_328_residues
MKLERNLGFDLQRATEAAALRSARWMGRGDKNEADGAAVDAMRFALNATDMDGIVVIGEGEKDEAPMLYIGEQIGNGSEP
RVDIAVDPVEGTTLLAQGMPGAIAVVAAAERGSLFNPPGIVYMDKIAVGESAKGSIDINASVEDNIRSVAKALKKRVEDV
TVIVLDRPRHHDVIARIREMGARIKLILHGDVAASLMPSMLEAPADILMGIGGAPESVISACAMKCTGGEIQCKLWPRND
RERDLARQNGLNLDKVYTTNDLVQGDNIFWAATGITTGDFLKGVQFFGWGATTHSLVMRSASGTVRYIESRHRWDKLMRI
SDLPFAEH
>Mature_328_residues
MKLERNLGFDLQRATEAAALRSARWMGRGDKNEADGAAVDAMRFALNATDMDGIVVIGEGEKDEAPMLYIGEQIGNGSEP
RVDIAVDPVEGTTLLAQGMPGAIAVVAAAERGSLFNPPGIVYMDKIAVGESAKGSIDINASVEDNIRSVAKALKKRVEDV
TVIVLDRPRHHDVIARIREMGARIKLILHGDVAASLMPSMLEAPADILMGIGGAPESVISACAMKCTGGEIQCKLWPRND
RERDLARQNGLNLDKVYTTNDLVQGDNIFWAATGITTGDFLKGVQFFGWGATTHSLVMRSASGTVRYIESRHRWDKLMRI
SDLPFAEH

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is essential for growth on gluconeogenic carbon sources. Also displays a low activity toward glucose 6- phosphate, and fructose 6-phosphate, glycerol 3-phosphate, ribulose 1,5-

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=327, Percent_Identity=45.8715596330275, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1789298, Length=320, Percent_Identity=42.5, Blast_Score=243, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35513; Mature: 35513

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLERNLGFDLQRATEAAALRSARWMGRGDKNEADGAAVDAMRFALNATDMDGIVVIGEG
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECC
EKDEAPMLYIGEQIGNGSEPRVDIAVDPVEGTTLLAQGMPGAIAVVAAAERGSLFNPPGI
CCCCCCEEEEEHHCCCCCCCEEEEEECCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCE
VYMDKIAVGESAKGSIDINASVEDNIRSVAKALKKRVEDVTVIVLDRPRHHDVIARIREM
EEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHC
GARIKLILHGDVAASLMPSMLEAPADILMGIGGAPESVISACAMKCTGGEIQCKLWPRND
CCEEEEEEECCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
RERDLARQNGLNLDKVYTTNDLVQGDNIFWAATGITTGDFLKGVQFFGWGATTHSLVMRS
HHHHHHHHCCCCCCEEECCCCEEECCCEEEEEECCCCHHHHHHHHHEECCCHHHHHHEEC
ASGTVRYIESRHRWDKLMRISDLPFAEH
CCCCEEHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLERNLGFDLQRATEAAALRSARWMGRGDKNEADGAAVDAMRFALNATDMDGIVVIGEG
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECC
EKDEAPMLYIGEQIGNGSEPRVDIAVDPVEGTTLLAQGMPGAIAVVAAAERGSLFNPPGI
CCCCCCEEEEEHHCCCCCCCEEEEEECCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCE
VYMDKIAVGESAKGSIDINASVEDNIRSVAKALKKRVEDVTVIVLDRPRHHDVIARIREM
EEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHC
GARIKLILHGDVAASLMPSMLEAPADILMGIGGAPESVISACAMKCTGGEIQCKLWPRND
CCEEEEEEECCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
RERDLARQNGLNLDKVYTTNDLVQGDNIFWAATGITTGDFLKGVQFFGWGATTHSLVMRS
HHHHHHHHCCCCCCEEECCCCEEECCCEEEEEECCCCHHHHHHHHHEECCCHHHHHHEEC
ASGTVRYIESRHRWDKLMRISDLPFAEH
CCCCEEHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]