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The map label for this gene is trpF [H]

Identifier: 159899758

GI number: 159899758

Start: 4101253

End: 4101924

Strand: Reverse

Name: trpF [H]

Synonym: Haur_3240

Alternate gene names: 159899758

Gene position: 4101924-4101253 (Counterclockwise)

Preceding gene: 159899759

Following gene: 159899757

Centisome position: 64.63

GC content: 52.68

Gene sequence:

>672_bases
ATGAGTTGGCCTGAACAGGCCATTAAAATCTGTGGTGTGCGTAGTGTCGAAGCCGCTGTTACAGCGGCTTTGGCAGGCGC
AGACCTAATTGGCATGATCTTCGCTCCCAGTAAACGCCAAATCCAGCCAAGCTTGGCGCTTGAGATTGTTCAGGCGGTGC
GGGCAACTGCCATGCCATGTCAATTGGTTGGGGTGTTTGCCAATGCCAGCGCCGCCGAGATTAATCAGCTGGCGCAGCAG
GTTGGCCTCGATCTAGTGCAGCTTAGCGGCGATGAAGATCCAACGATCGTCAATGAAATCCAATTCCCAATGCTTAAAGC
TGTCCGTTTAACCAATCAAAATAATGAGCAAGCGTGGTATGATATAGCCCAAAGCCATCAACACGTGCGCTTGGTGGTCG
ATGCTCATGTGCCAGGCTCATATGGTGGGGCTGGCGTGTTGGCCGATTGGTCAGCCGCTGCCCAATTGGCCCAAACAACG
CCCTTATTACTGGCGGGCGGGCTAGAACCAAACAATGTGGCTCAAGCAATTCAAGCAGTTGCCCCATGGGGGGTCGATGT
CAGTAGCGGCATCGAAACCGCTGGCATCAAAGATCTAACCAAAATAACTCAATTTGTGAAAACCGCGCAGCAAGCCTTGG
ATGCGCTGCGTGTTGCTAGGAGGAATTCATGA

Upstream 100 bases:

>100_bases
AAAAGGCCGAGCCAGTCGCTGAAGCTCCAGCTCCAGTCGAGCCAGCCAAAAAACAACCACGTCGCCGTAAAAAGGCCGCC
AGCGAAACTGGAGAAGAAGC

Downstream 100 bases:

>100_bases
AATTTGGTAAATTGTTGCGCTTCGGTATCATTGCTGGTGCAGGAGCCTTGGTTTATCGGGTTTATAAACAATATAAGGCG
GATCAAGCATTTGAGTTGGC

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSWPEQAIKICGVRSVEAAVTAALAGADLIGMIFAPSKRQIQPSLALEIVQAVRATAMPCQLVGVFANASAAEINQLAQQ
VGLDLVQLSGDEDPTIVNEIQFPMLKAVRLTNQNNEQAWYDIAQSHQHVRLVVDAHVPGSYGGAGVLADWSAAAQLAQTT
PLLLAGGLEPNNVAQAIQAVAPWGVDVSSGIETAGIKDLTKITQFVKTAQQALDALRVARRNS

Sequences:

>Translated_223_residues
MSWPEQAIKICGVRSVEAAVTAALAGADLIGMIFAPSKRQIQPSLALEIVQAVRATAMPCQLVGVFANASAAEINQLAQQ
VGLDLVQLSGDEDPTIVNEIQFPMLKAVRLTNQNNEQAWYDIAQSHQHVRLVVDAHVPGSYGGAGVLADWSAAAQLAQTT
PLLLAGGLEPNNVAQAIQAVAPWGVDVSSGIETAGIKDLTKITQFVKTAQQALDALRVARRNS
>Mature_222_residues
SWPEQAIKICGVRSVEAAVTAALAGADLIGMIFAPSKRQIQPSLALEIVQAVRATAMPCQLVGVFANASAAEINQLAQQV
GLDLVQLSGDEDPTIVNEIQFPMLKAVRLTNQNNEQAWYDIAQSHQHVRLVVDAHVPGSYGGAGVLADWSAAAQLAQTTP
LLLAGGLEPNNVAQAIQAVAPWGVDVSSGIETAGIKDLTKITQFVKTAQQALDALRVARRNS

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320210, Length=216, Percent_Identity=36.5740740740741, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23524; Mature: 23393

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWPEQAIKICGVRSVEAAVTAALAGADLIGMIFAPSKRQIQPSLALEIVQAVRATAMPC
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCH
QLVGVFANASAAEINQLAQQVGLDLVQLSGDEDPTIVNEIQFPMLKAVRLTNQNNEQAWY
HHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
DIAQSHQHVRLVVDAHVPGSYGGAGVLADWSAAAQLAQTTPLLLAGGLEPNNVAQAIQAV
HHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHH
APWGVDVSSGIETAGIKDLTKITQFVKTAQQALDALRVARRNS
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWPEQAIKICGVRSVEAAVTAALAGADLIGMIFAPSKRQIQPSLALEIVQAVRATAMPC
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHCCCH
QLVGVFANASAAEINQLAQQVGLDLVQLSGDEDPTIVNEIQFPMLKAVRLTNQNNEQAWY
HHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
DIAQSHQHVRLVVDAHVPGSYGGAGVLADWSAAAQLAQTTPLLLAGGLEPNNVAQAIQAV
HHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHH
APWGVDVSSGIETAGIKDLTKITQFVKTAQQALDALRVARRNS
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA