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The map label for this gene is yomI [H]

Identifier: 159899595

GI number: 159899595

Start: 3885004

End: 3887337

Strand: Reverse

Name: yomI [H]

Synonym: Haur_3076

Alternate gene names: 159899595

Gene position: 3887337-3885004 (Counterclockwise)

Preceding gene: 159899597

Following gene: 159899594

Centisome position: 61.25

GC content: 53.17

Gene sequence:

>2334_bases
ATGGCTGCCATGAAGCGCGATGAGATTCTTATGCTGAAAAAAATTCCACACGTAGCCTTGATTGTGCTACTGCTAGCCAG
TTGTAGCCGCGATGTCGTCGGTCAACCAACCGCCACGCCGCTACCATCCCCTGCCCAATTGTTGCAGCAAGCCGAGCAAC
ATCAGCAAGCCGACCAAGTTGATTTGGCCTTGAGCGATTATCAACAGGTGTTATTGCAATACCCCGATGCGCCCGAAGCG
CGGGTAGCCAAATTTGGGGTAGCCTATAGTGCCTTCTTACGCCAAGATTGGGCTGCTGCATGGTCGCAATTAACTTCCTT
TATCAACGAGCAAACCCACGATCAATGGCATTTGCGGGCGCTCTTTTTGCTGGGACGGGTCGCTGAAATTCAAGGTGACC
ATGCGATCGCGATCGAGGCCTATCAACAATATGAAGATCTTAAAGGCTTGTTGAGTGGCTATGCAGCTCAGCGCCGTGCC
GCCCAACTGCAAGCAACCAACCAAACCGAGCAAGCGATTGCGGCCTATGCTGCCAGCGGACGCTACGATATGGCTGGGCC
GCAGCGGGTCGCCAGCTTAAACAAAGCCTTAGAATTTTATGATCAAACGGGGCAGGCCGAGCAAGCACTTACTCAACTCG
AAGTTATTTTGAGCTTTGCCCGAACCCCAAGTTTCCGTTCAACGACCTTGCTTGATGCAGCGCGACGTGCTCAGCGCTTG
GGCAAAACTGAACAAGCCCGAATATGGCTGCGCGAAATCATTAACCAACACCCAACCTTGAGCGAAGCTCCAATTGCGAT
TGATGAACTGGCAGCTTTGGGCGAATCAACCCCAGTGCTGGCCGCCGCTGGGATTGCCTATAACCATGGTCAATATCTTG
ATGCGATCAGTTTGTTCGACCAAGTGCTGGCCAATGGCCTGAGTGGCGAAGAAGCCGCCGAAATCGAGCGCAAACGGGCT
TTGGCCTTGCGCCAGCTCGATGATTATGCTGGTGCACAAGCAGCATTTAATAGTATTGCCGAGCGTTTTGCCGAGTTGCC
GATTGGCCGCCAAGCACGACTTGATGCGATTCAAACCCAAGGCCAAGCGGGTGATCGTGAAGGCTCACGTTTGGCCTATC
TCGATTTTGCCGAGCGTTATGCCGATGATCCGTTAGCACCCGAAGCTTTGCGCCGCGTCGTCGAAATTACCTCGTGGAGC
GGCGATCCGGCAGCCACAGCCAATGCGCAAATTATGCTTGGCCAGCGCTACCCTTGGAGCCACGAAGGCCAGCAAGCCTT
GCACGCCGCAGGCCGTTATGCCTGGGATACGGGGCAGGTTGAGCAGGCGGCAGCAGTTTGGCAATTATTAGGCGATAGCA
ATATTGGGCCGCCTCGCGCCGAAGGCTATTATTGGCTGGGGCGCTTGGAAATTAGCCGTGGCAATCGGGAAAAAGGCGAG
CAATTGCTACGTTCGGCTCAATCAGCTGATCCAAATTCGTATTATGCGGCACGGGTTGCCGATGCCCTCAACATTAACGA
TGGCGATCAACTGCCGATTGGCTCGCCAATTAGCCCTGAGGCCGAACAAGCAGGTTGGCAATGGATCGCTAGTTGGTCAA
CTGCACCAACCAGCGCCACCTTAGATACTGAGCCATATAGTTTACGCGCCGAAGAACTAAGCTGGACCGATTTGCATAGC
GAAGCCCAAGCCGAGTGGATTGCCGCACGTGATGCTGCCTTGAATAATCCATTTAGCATTTATCGGGTTGCTTTGGCCGC
TTTACGCAGCGATATGCCCTATGCTACCGTGACTACAGCTCAAAAGTTGGTGCAACTTGCGCCAATTGAGGCAGGCGAGC
CAAGTGTCGCGATTCGCCAATTGCTCTATCCAACACCGTATCCCAGCGCGGTTGTGACCAAAAGCCAAGAGTTTGGGCTT
GATCCACGGGTGTTGTATGCAGTGATGCGCCAAGAGAGTATTTTTAATCCAAATGCAACGTCATGGGTGGGGGCGCGTGG
CTTGGCCCAAGTGATGCCCAGCACTGGCGAGGGCATCGCCCAGAATTTAGGCATTGAGGGCTTTAGCGTCGATGATTTGT
ATAATCCGGTGACTTCGATTCGTTTTGGAGCTTATTATATCGATGCTCAAATCGAATATATGAGTGGCAGCCTACCCGGC
GCGTTTGCCGCCTATAACGGTGGGCCTGGTAATGCCGAGCGTTGGGCTGATGGTCGCGTGGTGGCTGATCCCGACCGTTT
TATTGAAATTATTGATTATGCTGAAACTCGCCACTATGTTGAAGTAGTTTATGCCAACTATGGAGCCTATCGGCGCTTGT
ATCAGCAACCATAA

Upstream 100 bases:

>100_bases
AGGTATCAAGCGGGATTTGGCGATTGTTAAGCAAAATACTGCAAAATCTCATCAAGTTCTTAGCCAGTTGGCACGGAGTT
TGCAGGGTCGCTATGCTACA

Downstream 100 bases:

>100_bases
GCAAGAACAAAGAACATAGAGCATAGAACATAGGGAGTTTTGATCCACGAAGGGCACGAAGGGAGATTAGGCTATCGGCT
TTTGGCTCTAGGCTTTTGGA

Product: lytic transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MAAMKRDEILMLKKIPHVALIVLLLASCSRDVVGQPTATPLPSPAQLLQQAEQHQQADQVDLALSDYQQVLLQYPDAPEA
RVAKFGVAYSAFLRQDWAAAWSQLTSFINEQTHDQWHLRALFLLGRVAEIQGDHAIAIEAYQQYEDLKGLLSGYAAQRRA
AQLQATNQTEQAIAAYAASGRYDMAGPQRVASLNKALEFYDQTGQAEQALTQLEVILSFARTPSFRSTTLLDAARRAQRL
GKTEQARIWLREIINQHPTLSEAPIAIDELAALGESTPVLAAAGIAYNHGQYLDAISLFDQVLANGLSGEEAAEIERKRA
LALRQLDDYAGAQAAFNSIAERFAELPIGRQARLDAIQTQGQAGDREGSRLAYLDFAERYADDPLAPEALRRVVEITSWS
GDPAATANAQIMLGQRYPWSHEGQQALHAAGRYAWDTGQVEQAAAVWQLLGDSNIGPPRAEGYYWLGRLEISRGNREKGE
QLLRSAQSADPNSYYAARVADALNINDGDQLPIGSPISPEAEQAGWQWIASWSTAPTSATLDTEPYSLRAEELSWTDLHS
EAQAEWIAARDAALNNPFSIYRVALAALRSDMPYATVTTAQKLVQLAPIEAGEPSVAIRQLLYPTPYPSAVVTKSQEFGL
DPRVLYAVMRQESIFNPNATSWVGARGLAQVMPSTGEGIAQNLGIEGFSVDDLYNPVTSIRFGAYYIDAQIEYMSGSLPG
AFAAYNGGPGNAERWADGRVVADPDRFIEIIDYAETRHYVEVVYANYGAYRRLYQQP

Sequences:

>Translated_777_residues
MAAMKRDEILMLKKIPHVALIVLLLASCSRDVVGQPTATPLPSPAQLLQQAEQHQQADQVDLALSDYQQVLLQYPDAPEA
RVAKFGVAYSAFLRQDWAAAWSQLTSFINEQTHDQWHLRALFLLGRVAEIQGDHAIAIEAYQQYEDLKGLLSGYAAQRRA
AQLQATNQTEQAIAAYAASGRYDMAGPQRVASLNKALEFYDQTGQAEQALTQLEVILSFARTPSFRSTTLLDAARRAQRL
GKTEQARIWLREIINQHPTLSEAPIAIDELAALGESTPVLAAAGIAYNHGQYLDAISLFDQVLANGLSGEEAAEIERKRA
LALRQLDDYAGAQAAFNSIAERFAELPIGRQARLDAIQTQGQAGDREGSRLAYLDFAERYADDPLAPEALRRVVEITSWS
GDPAATANAQIMLGQRYPWSHEGQQALHAAGRYAWDTGQVEQAAAVWQLLGDSNIGPPRAEGYYWLGRLEISRGNREKGE
QLLRSAQSADPNSYYAARVADALNINDGDQLPIGSPISPEAEQAGWQWIASWSTAPTSATLDTEPYSLRAEELSWTDLHS
EAQAEWIAARDAALNNPFSIYRVALAALRSDMPYATVTTAQKLVQLAPIEAGEPSVAIRQLLYPTPYPSAVVTKSQEFGL
DPRVLYAVMRQESIFNPNATSWVGARGLAQVMPSTGEGIAQNLGIEGFSVDDLYNPVTSIRFGAYYIDAQIEYMSGSLPG
AFAAYNGGPGNAERWADGRVVADPDRFIEIIDYAETRHYVEVVYANYGAYRRLYQQP
>Mature_776_residues
AAMKRDEILMLKKIPHVALIVLLLASCSRDVVGQPTATPLPSPAQLLQQAEQHQQADQVDLALSDYQQVLLQYPDAPEAR
VAKFGVAYSAFLRQDWAAAWSQLTSFINEQTHDQWHLRALFLLGRVAEIQGDHAIAIEAYQQYEDLKGLLSGYAAQRRAA
QLQATNQTEQAIAAYAASGRYDMAGPQRVASLNKALEFYDQTGQAEQALTQLEVILSFARTPSFRSTTLLDAARRAQRLG
KTEQARIWLREIINQHPTLSEAPIAIDELAALGESTPVLAAAGIAYNHGQYLDAISLFDQVLANGLSGEEAAEIERKRAL
ALRQLDDYAGAQAAFNSIAERFAELPIGRQARLDAIQTQGQAGDREGSRLAYLDFAERYADDPLAPEALRRVVEITSWSG
DPAATANAQIMLGQRYPWSHEGQQALHAAGRYAWDTGQVEQAAAVWQLLGDSNIGPPRAEGYYWLGRLEISRGNREKGEQ
LLRSAQSADPNSYYAARVADALNINDGDQLPIGSPISPEAEQAGWQWIASWSTAPTSATLDTEPYSLRAEELSWTDLHSE
AQAEWIAARDAALNNPFSIYRVALAALRSDMPYATVTTAQKLVQLAPIEAGEPSVAIRQLLYPTPYPSAVVTKSQEFGLD
PRVLYAVMRQESIFNPNATSWVGARGLAQVMPSTGEGIAQNLGIEGFSVDDLYNPVTSIRFGAYYIDAQIEYMSGSLPGA
FAAYNGGPGNAERWADGRVVADPDRFIEIIDYAETRHYVEVVYANYGAYRRLYQQP

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 10 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=132, Percent_Identity=38.6363636363636, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR008258
- InterPro:   IPR016047
- InterPro:   IPR010090
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01551 Peptidase_M23; PF10145 PhageMin_Tail; PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 85369; Mature: 85238

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAMKRDEILMLKKIPHVALIVLLLASCSRDVVGQPTATPLPSPAQLLQQAEQHQQADQV
CCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DLALSDYQQVLLQYPDAPEARVAKFGVAYSAFLRQDWAAAWSQLTSFINEQTHDQWHLRA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LFLLGRVAEIQGDHAIAIEAYQQYEDLKGLLSGYAAQRRAAQLQATNQTEQAIAAYAASG
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
RYDMAGPQRVASLNKALEFYDQTGQAEQALTQLEVILSFARTPSFRSTTLLDAARRAQRL
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GKTEQARIWLREIINQHPTLSEAPIAIDELAALGESTPVLAAAGIAYNHGQYLDAISLFD
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEECCCEECCCHHHHHHHHHH
QVLANGLSGEEAAEIERKRALALRQLDDYAGAQAAFNSIAERFAELPIGRQARLDAIQTQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHC
GQAGDREGSRLAYLDFAERYADDPLAPEALRRVVEITSWSGDPAATANAQIMLGQRYPWS
CCCCCCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
HEGQQALHAAGRYAWDTGQVEQAAAVWQLLGDSNIGPPRAEGYYWLGRLEISRGNREKGE
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHH
QLLRSAQSADPNSYYAARVADALNINDGDQLPIGSPISPEAEQAGWQWIASWSTAPTSAT
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCCCE
LDTEPYSLRAEELSWTDLHSEAQAEWIAARDAALNNPFSIYRVALAALRSDMPYATVTTA
ECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
QKLVQLAPIEAGEPSVAIRQLLYPTPYPSAVVTKSQEFGLDPRVLYAVMRQESIFNPNAT
HHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHEECCHHHCCCHHHHHHHHHHHHCCCCCCC
SWVGARGLAQVMPSTGEGIAQNLGIEGFSVDDLYNPVTSIRFGAYYIDAQIEYMSGSLPG
CHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHCHHHHHEECEEEEEEEEEEECCCCCC
AFAAYNGGPGNAERWADGRVVADPDRFIEIIDYAETRHYVEVVYANYGAYRRLYQQP
CEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHCCC
>Mature Secondary Structure 
AAMKRDEILMLKKIPHVALIVLLLASCSRDVVGQPTATPLPSPAQLLQQAEQHQQADQV
CCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
DLALSDYQQVLLQYPDAPEARVAKFGVAYSAFLRQDWAAAWSQLTSFINEQTHDQWHLRA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LFLLGRVAEIQGDHAIAIEAYQQYEDLKGLLSGYAAQRRAAQLQATNQTEQAIAAYAASG
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
RYDMAGPQRVASLNKALEFYDQTGQAEQALTQLEVILSFARTPSFRSTTLLDAARRAQRL
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GKTEQARIWLREIINQHPTLSEAPIAIDELAALGESTPVLAAAGIAYNHGQYLDAISLFD
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEECCCEECCCHHHHHHHHHH
QVLANGLSGEEAAEIERKRALALRQLDDYAGAQAAFNSIAERFAELPIGRQARLDAIQTQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHC
GQAGDREGSRLAYLDFAERYADDPLAPEALRRVVEITSWSGDPAATANAQIMLGQRYPWS
CCCCCCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCC
HEGQQALHAAGRYAWDTGQVEQAAAVWQLLGDSNIGPPRAEGYYWLGRLEISRGNREKGE
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHH
QLLRSAQSADPNSYYAARVADALNINDGDQLPIGSPISPEAEQAGWQWIASWSTAPTSAT
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCCCE
LDTEPYSLRAEELSWTDLHSEAQAEWIAARDAALNNPFSIYRVALAALRSDMPYATVTTA
ECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
QKLVQLAPIEAGEPSVAIRQLLYPTPYPSAVVTKSQEFGLDPRVLYAVMRQESIFNPNAT
HHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHEECCHHHCCCHHHHHHHHHHHHCCCCCCC
SWVGARGLAQVMPSTGEGIAQNLGIEGFSVDDLYNPVTSIRFGAYYIDAQIEYMSGSLPG
CHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHCHHHHHEECEEEEEEEEEEECCCCCC
AFAAYNGGPGNAERWADGRVVADPDRFIEIIDYAETRHYVEVVYANYGAYRRLYQQP
CEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]