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The map label for this gene is phoR [H]

Identifier: 159899317

GI number: 159899317

Start: 3557303

End: 3558775

Strand: Reverse

Name: phoR [H]

Synonym: Haur_2798

Alternate gene names: 159899317

Gene position: 3558775-3557303 (Counterclockwise)

Preceding gene: 159899318

Following gene: 159899314

Centisome position: 56.07

GC content: 53.97

Gene sequence:

>1473_bases
ATGACCCTACGCTATCGGCTAACCTTCATTTCTGTGGCCTTTATGACCCTTGGATTGTTAATTCTAGGGTTGACACTCTA
TTCGGCGGAACGGGCGATTTTGCTCAACGGCGTGCGCGATGATTTGGTGCGGGCTACCAACCAAATTCAGAGCCAATATG
CCGAGGCCAAAAAACCGCTTGAGCGCTATTTTAGCGGCACAAGTGTTTCGTTGTTGCCAGTGCCCAACGAAGATTTTGAA
GGTTCGCCGATTTCGGTGGCGGTGTATTACCCCAATGGCGTGCGATTGGCCTCAACACCTTCGTTTATGGGCGAAGGCCC
GACCCTCGATAGCACTGAATTAGCCTCGGCACTAGAGAAAAATTCAGTCATTAACACCAAACCTTCGTCGTATGGTCGCA
CAATGCAGGTGGTTTCGCCCTTGACCTTCGATCATACCGTGGTTGGGGTGTTGGTGGCCAGTCAATCGCTGCGCACGGTT
GATCGGGCCTTGGATACCTTGTCGTTGGTGTTTTTGATTGCTGGCTCGCTCACAGTGGTGCTGATGTTTTTGGGCATCAG
CCAAATCACCAAGCGCGGCTTGCGCCCAATTGATATGATCGCCAACACCGCTGAGCAAATTGTGCGGGCCGAAGATTTGA
GCCGCCGTATCGCCGTGGCCAACCCCCACGATGAGCTTGGGCGATTAGCCACGATTACCAACGATTTGCTAGCGCGGATG
GAAGGTTTGTTCAACACCCAAAAACGCCTGACCGCCGATGTTTCGCACGAATTGCGCACCCCACTAGCGGCGATGCGCGG
TAACCTTGAGGTGCTGCGGCGCGGAGCTATGCGCAACCCCGAATTGCTCAACGAATCGCTGAGCGACTTAGAACGTGAGG
TAGCGCGGCTCAATCGTTTGGTCAACGACCTGCTGTTTTTGGCTCAAACCGAGGCTGGCGTACAAATGCGTAGCGAGCCA
GTTGAGCTTGATACCTTGATTTTGGAAGTGTTCCGCGAATTGCGCCCACTGGCTGAGCATGTCAAGCTCCAAATCGGCAG
CGAAGATCAAGCAACTGTTATCGGTGATCGCGATCGGCTTAAGCAAGCAATGCTCAATTTGGCCTATAACGCGATTCAGC
ATACGCCCGAAGGTGGCGCAGTCACTCTAAGTTTGGAGCGGGTTGGGCGCGAGGTGGCTTTGCGGGTGCAAGATACTGGC
GAGGGCATTCCACCCGATATTCTGCCTAATATTTTCCAGCGTTTCTATCGTGCCGACAAATCGCGGGTGCGCAAAGGCGG
CGGAGCTGGCATCGGTCTGGCGATCGTCAAATGGATTACCGATGCCCATCGCGGTACAATCGAAGTTCGTTCAAATGTTG
GCGAAGGCAGCCTCTTCACCTTGTGGCTACCCCTCGCTCCCGCCACCGATCGCTTGATTACTGGGCAATTACGTGAATCG
CCCTCGCAACCGTTGCCAATTGTCAGGCAATAA

Upstream 100 bases:

>100_bases
GCTATCTGCGCCAAAAACTCGAAGAATCGGGCGAAGGCCGCATGCTGCACACCGTGCGTGGAGCTGGCTACATTTTACGT
GAACAACCCTACGGTGAACG

Downstream 100 bases:

>100_bases
GGGTTAGCTAGAGACCATAGCTGGAAGTTCTAATAGCTATCATGGCATAGTTTCCTCTCGCCTGCTGGAAGGGCAGAGAA
TGAACCCTCTGTTCTGTTCT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MTLRYRLTFISVAFMTLGLLILGLTLYSAERAILLNGVRDDLVRATNQIQSQYAEAKKPLERYFSGTSVSLLPVPNEDFE
GSPISVAVYYPNGVRLASTPSFMGEGPTLDSTELASALEKNSVINTKPSSYGRTMQVVSPLTFDHTVVGVLVASQSLRTV
DRALDTLSLVFLIAGSLTVVLMFLGISQITKRGLRPIDMIANTAEQIVRAEDLSRRIAVANPHDELGRLATITNDLLARM
EGLFNTQKRLTADVSHELRTPLAAMRGNLEVLRRGAMRNPELLNESLSDLEREVARLNRLVNDLLFLAQTEAGVQMRSEP
VELDTLILEVFRELRPLAEHVKLQIGSEDQATVIGDRDRLKQAMLNLAYNAIQHTPEGGAVTLSLERVGREVALRVQDTG
EGIPPDILPNIFQRFYRADKSRVRKGGGAGIGLAIVKWITDAHRGTIEVRSNVGEGSLFTLWLPLAPATDRLITGQLRES
PSQPLPIVRQ

Sequences:

>Translated_490_residues
MTLRYRLTFISVAFMTLGLLILGLTLYSAERAILLNGVRDDLVRATNQIQSQYAEAKKPLERYFSGTSVSLLPVPNEDFE
GSPISVAVYYPNGVRLASTPSFMGEGPTLDSTELASALEKNSVINTKPSSYGRTMQVVSPLTFDHTVVGVLVASQSLRTV
DRALDTLSLVFLIAGSLTVVLMFLGISQITKRGLRPIDMIANTAEQIVRAEDLSRRIAVANPHDELGRLATITNDLLARM
EGLFNTQKRLTADVSHELRTPLAAMRGNLEVLRRGAMRNPELLNESLSDLEREVARLNRLVNDLLFLAQTEAGVQMRSEP
VELDTLILEVFRELRPLAEHVKLQIGSEDQATVIGDRDRLKQAMLNLAYNAIQHTPEGGAVTLSLERVGREVALRVQDTG
EGIPPDILPNIFQRFYRADKSRVRKGGGAGIGLAIVKWITDAHRGTIEVRSNVGEGSLFTLWLPLAPATDRLITGQLRES
PSQPLPIVRQ
>Mature_489_residues
TLRYRLTFISVAFMTLGLLILGLTLYSAERAILLNGVRDDLVRATNQIQSQYAEAKKPLERYFSGTSVSLLPVPNEDFEG
SPISVAVYYPNGVRLASTPSFMGEGPTLDSTELASALEKNSVINTKPSSYGRTMQVVSPLTFDHTVVGVLVASQSLRTVD
RALDTLSLVFLIAGSLTVVLMFLGISQITKRGLRPIDMIANTAEQIVRAEDLSRRIAVANPHDELGRLATITNDLLARME
GLFNTQKRLTADVSHELRTPLAAMRGNLEVLRRGAMRNPELLNESLSDLEREVARLNRLVNDLLFLAQTEAGVQMRSEPV
ELDTLILEVFRELRPLAEHVKLQIGSEDQATVIGDRDRLKQAMLNLAYNAIQHTPEGGAVTLSLERVGREVALRVQDTGE
GIPPDILPNIFQRFYRADKSRVRKGGGAGIGLAIVKWITDAHRGTIEVRSNVGEGSLFTLWLPLAPATDRLITGQLRESP
SQPLPIVRQ

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=304, Percent_Identity=33.8815789473684, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=37.1841155234657, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1786600, Length=277, Percent_Identity=32.129963898917, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=28.4671532846715, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=33.6363636363636, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=28.7822878228782, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790861, Length=237, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=29.0566037735849, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=32.0512820512821, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790551, Length=318, Percent_Identity=29.2452830188679, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=29.2181069958848, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=30.2904564315353, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=30.4526748971193, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789403, Length=293, Percent_Identity=25.938566552901, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=297, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=26.7543859649123, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787374, Length=287, Percent_Identity=25.4355400696864, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=243, Percent_Identity=27.9835390946502, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082128, Length=304, Percent_Identity=25.9868421052632, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=28.0172413793103, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53961; Mature: 53830

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRYRLTFISVAFMTLGLLILGLTLYSAERAILLNGVRDDLVRATNQIQSQYAEAKKPL
CCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ERYFSGTSVSLLPVPNEDFEGSPISVAVYYPNGVRLASTPSFMGEGPTLDSTELASALEK
HHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHH
NSVINTKPSSYGRTMQVVSPLTFDHTVVGVLVASQSLRTVDRALDTLSLVFLIAGSLTVV
CCCCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFLGISQITKRGLRPIDMIANTAEQIVRAEDLSRRIAVANPHDELGRLATITNDLLARM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHH
EGLFNTQKRLTADVSHELRTPLAAMRGNLEVLRRGAMRNPELLNESLSDLEREVARLNRL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VNDLLFLAQTEAGVQMRSEPVELDTLILEVFRELRPLAEHVKLQIGSEDQATVIGDRDRL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCHHHH
KQAMLNLAYNAIQHTPEGGAVTLSLERVGREVALRVQDTGEGIPPDILPNIFQRFYRADK
HHHHHHHHHHHHHCCCCCCEEEEEHHHCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHH
SRVRKGGGAGIGLAIVKWITDAHRGTIEVRSNVGEGSLFTLWLPLAPATDRLITGQLRES
HHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHEECHHHCC
PSQPLPIVRQ
CCCCCCCCCC
>Mature Secondary Structure 
TLRYRLTFISVAFMTLGLLILGLTLYSAERAILLNGVRDDLVRATNQIQSQYAEAKKPL
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ERYFSGTSVSLLPVPNEDFEGSPISVAVYYPNGVRLASTPSFMGEGPTLDSTELASALEK
HHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHH
NSVINTKPSSYGRTMQVVSPLTFDHTVVGVLVASQSLRTVDRALDTLSLVFLIAGSLTVV
CCCCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFLGISQITKRGLRPIDMIANTAEQIVRAEDLSRRIAVANPHDELGRLATITNDLLARM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHH
EGLFNTQKRLTADVSHELRTPLAAMRGNLEVLRRGAMRNPELLNESLSDLEREVARLNRL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VNDLLFLAQTEAGVQMRSEPVELDTLILEVFRELRPLAEHVKLQIGSEDQATVIGDRDRL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCHHHH
KQAMLNLAYNAIQHTPEGGAVTLSLERVGREVALRVQDTGEGIPPDILPNIFQRFYRADK
HHHHHHHHHHHHHCCCCCCEEEEEHHHCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHH
SRVRKGGGAGIGLAIVKWITDAHRGTIEVRSNVGEGSLFTLWLPLAPATDRLITGQLRES
HHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHEECHHHCC
PSQPLPIVRQ
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]