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The map label for this gene is hdl IVa [H]

Identifier: 159899196

GI number: 159899196

Start: 3432641

End: 3433309

Strand: Reverse

Name: hdl IVa [H]

Synonym: Haur_2677

Alternate gene names: 159899196

Gene position: 3433309-3432641 (Counterclockwise)

Preceding gene: 159899198

Following gene: 159899195

Centisome position: 54.1

GC content: 52.77

Gene sequence:

>669_bases
ATGCCACGACCTGTATTTATCGATTTGTACTTTACCTTGATTGAGCCAGACCCCGCTTACAACTGGGCAACCTTGGCAGC
CCCGCTGCTCGGCATCGAGCAGCATGCCTTTCATGCTGCGGCTGGTCGTTCGTATCAAGCGCGGATGGTTGGCACCTATC
GTTTGGCTGAAGAGATTGTTGATCAAACCTTGGGCTATTTGGGGATGAGCGTTACACCTGAGGTGCATGCCACGCTGACC
AAACAGCGCTTGGAGTTTTTCAGCACGCTTCGCGTTTATCCCGATTCGATACCGACCTTGCAAGCCTTGCGAGCACGTGG
CCACCAAATTGCCTTGGTCACCAACTGCTCAGCCGAAACCATCCCGATGATGGAGCCGCTGGGTTTGCTAAATTTGTTTG
ATGCACTTGCCTACTCCTGCGATGTGCGTTCGGCCAAGCCTGAGCCTGGCATTTATCAGCATGCCCTCGATGTCTTGAAT
GTTGACCCGCGTGAGGTGGTGTATGTTGGTGATGGCGATACCCAAGAGCATGCTGGCGCAGCCAAATTTGGCATGACCAC
CGTACTGCTCCAGCGGCCTGAAGCTAAAATACGCGCTGTGCAAACCGATTATGTAATTAACTCGCTGACTGAATTATTGG
ATTTAGCGCCACTGAGCCAAGGAGCCTAA

Upstream 100 bases:

>100_bases
CAACCCTTCGGAATTAAAGGCCACAATCAGCCAGCATCGTACCATAAAACGCCAATCTGCATACAATAGCTGCAAGAATG
TTTTTTGCGACGGAGTATGT

Downstream 100 bases:

>100_bases
TGCTAGCAGTTATTATTGCCGACGCGCCGCAAGCCGATATTCGGGCGGCCTTGCCTTTATTGAGTAGTACCGATTTATTG
ATTGCTGCTGATGGCGGGGC

Product: HAD family hydrolase

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase IVA; Halocarboxylic acid halidohydrolase IVA; L-2-haloacid dehalogenase IVA [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MPRPVFIDLYFTLIEPDPAYNWATLAAPLLGIEQHAFHAAAGRSYQARMVGTYRLAEEIVDQTLGYLGMSVTPEVHATLT
KQRLEFFSTLRVYPDSIPTLQALRARGHQIALVTNCSAETIPMMEPLGLLNLFDALAYSCDVRSAKPEPGIYQHALDVLN
VDPREVVYVGDGDTQEHAGAAKFGMTTVLLQRPEAKIRAVQTDYVINSLTELLDLAPLSQGA

Sequences:

>Translated_222_residues
MPRPVFIDLYFTLIEPDPAYNWATLAAPLLGIEQHAFHAAAGRSYQARMVGTYRLAEEIVDQTLGYLGMSVTPEVHATLT
KQRLEFFSTLRVYPDSIPTLQALRARGHQIALVTNCSAETIPMMEPLGLLNLFDALAYSCDVRSAKPEPGIYQHALDVLN
VDPREVVYVGDGDTQEHAGAAKFGMTTVLLQRPEAKIRAVQTDYVINSLTELLDLAPLSQGA
>Mature_221_residues
PRPVFIDLYFTLIEPDPAYNWATLAAPLLGIEQHAFHAAAGRSYQARMVGTYRLAEEIVDQTLGYLGMSVTPEVHATLTK
QRLEFFSTLRVYPDSIPTLQALRARGHQIALVTNCSAETIPMMEPLGLLNLFDALAYSCDVRSAKPEPGIYQHALDVLNV
DPREVVYVGDGDTQEHAGAAKFGMTTVLLQRPEAKIRAVQTDYVINSLTELLDLAPLSQGA

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-3 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006388
- InterPro:   IPR006402
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 24443; Mature: 24312

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPVFIDLYFTLIEPDPAYNWATLAAPLLGIEQHAFHAAAGRSYQARMVGTYRLAEEIV
CCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
DQTLGYLGMSVTPEVHATLTKQRLEFFSTLRVYPDSIPTLQALRARGHQIALVTNCSAET
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCC
IPMMEPLGLLNLFDALAYSCDVRSAKPEPGIYQHALDVLNVDPREVVYVGDGDTQEHAGA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHCCH
AKFGMTTVLLQRPEAKIRAVQTDYVINSLTELLDLAPLSQGA
HHHHHHHEEHCCCCHHHEEHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRPVFIDLYFTLIEPDPAYNWATLAAPLLGIEQHAFHAAAGRSYQARMVGTYRLAEEIV
CCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
DQTLGYLGMSVTPEVHATLTKQRLEFFSTLRVYPDSIPTLQALRARGHQIALVTNCSAET
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCC
IPMMEPLGLLNLFDALAYSCDVRSAKPEPGIYQHALDVLNVDPREVVYVGDGDTQEHAGA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHCCH
AKFGMTTVLLQRPEAKIRAVQTDYVINSLTELLDLAPLSQGA
HHHHHHHEEHCCCCHHHEEHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1376111 [H]