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The map label for this gene is thiN [H]

Identifier: 159899195

GI number: 159899195

Start: 3431988

End: 3432641

Strand: Reverse

Name: thiN [H]

Synonym: Haur_2676

Alternate gene names: 159899195

Gene position: 3432641-3431988 (Counterclockwise)

Preceding gene: 159899196

Following gene: 159899189

Centisome position: 54.09

GC content: 53.98

Gene sequence:

>654_bases
ATGCTAGCAGTTATTATTGCCGACGCGCCGCAAGCCGATATTCGGGCGGCCTTGCCTTTATTGAGTAGTACCGATTTATT
GATTGCTGCTGATGGCGGGGCACGTCATGCCTTGAATCATGGGGTTACACCGCATGTGATTATCGGCGATTTGGATTCGA
TTCAGCCTGCAACCTTGGAGATTATGCAAGCCCGCAAGGTTGAGATTCAGCGCTTTCCAGCGGCCAAAAACGAAACCGAC
CTCGAATTGGCATTGTTGCTGGCGGCTGAACGCGGCGCGGATCAGATTCGGATTCTGGCGGCGCTTGGTGGTCGGCCCGA
TATGCATATGGCCAACCAACTCTTGCTGACCCATCCAGCCTTGATTGGGCGTGATGTGGCGTTGCTTGATGCCAATTGGG
AAGTGCGCTTAATTCGTGATCAATTGCAGCTGCAGGGTAAACTTGGTTTGCGGGTTTCGCTGTTGCCCTTGGGCGATGTT
GCGGGAGTACGTACTGAGGGCTTGCGCTACCCATTGCGCGACGAAGATTTGCCAATTGGCCCAGCGCGAGGCGTTAGCAA
CGAATTTGCAACAGAATCGGCCCAAGTCAGCATTCGCTCAGGGCTGTTGTTGGCGATGATCGAACGCGAGCTACAGTCGG
GATACTTGGCTTAA

Upstream 100 bases:

>100_bases
TCCAGCGGCCTGAAGCTAAAATACGCGCTGTGCAAACCGATTATGTAATTAACTCGCTGACTGAATTATTGGATTTAGCG
CCACTGAGCCAAGGAGCCTA

Downstream 100 bases:

>100_bases
ATAAAAACAGGCGGAGCAACTATTGCCCCGCCTGTTGCATTCCGAACGTAGTTATTCAGCAGTAATCAGATTCTTGCCGA
ATTGCAAGCTTGGTGCTGCA

Product: thiamine pyrophosphokinase

Products: NA

Alternate protein names: TPK; Thiamine diphosphokinase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MLAVIIADAPQADIRAALPLLSSTDLLIAADGGARHALNHGVTPHVIIGDLDSIQPATLEIMQARKVEIQRFPAAKNETD
LELALLLAAERGADQIRILAALGGRPDMHMANQLLLTHPALIGRDVALLDANWEVRLIRDQLQLQGKLGLRVSLLPLGDV
AGVRTEGLRYPLRDEDLPIGPARGVSNEFATESAQVSIRSGLLLAMIERELQSGYLA

Sequences:

>Translated_217_residues
MLAVIIADAPQADIRAALPLLSSTDLLIAADGGARHALNHGVTPHVIIGDLDSIQPATLEIMQARKVEIQRFPAAKNETD
LELALLLAAERGADQIRILAALGGRPDMHMANQLLLTHPALIGRDVALLDANWEVRLIRDQLQLQGKLGLRVSLLPLGDV
AGVRTEGLRYPLRDEDLPIGPARGVSNEFATESAQVSIRSGLLLAMIERELQSGYLA
>Mature_217_residues
MLAVIIADAPQADIRAALPLLSSTDLLIAADGGARHALNHGVTPHVIIGDLDSIQPATLEIMQARKVEIQRFPAAKNETD
LELALLLAAERGADQIRILAALGGRPDMHMANQLLLTHPALIGRDVALLDANWEVRLIRDQLQLQGKLGLRVSLLPLGDV
AGVRTEGLRYPLRDEDLPIGPARGVSNEFATESAQVSIRSGLLLAMIERELQSGYLA

Specific function: Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate [H]

COG id: COG1564

COG function: function code H; Thiamine pyrophosphokinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine pyrophosphokinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006282
- InterPro:   IPR007373
- InterPro:   IPR007371 [H]

Pfam domain/function: PF04263 TPK_catalytic [H]

EC number: =2.7.6.2 [H]

Molecular weight: Translated: 23325; Mature: 23325

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVIIADAPQADIRAALPLLSSTDLLIAADGGARHALNHGVTPHVIIGDLDSIQPATLE
CEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCEEEEECCCCCCHHHHH
IMQARKVEIQRFPAAKNETDLELALLLAAERGADQIRILAALGGRPDMHMANQLLLTHPA
HHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCH
LIGRDVALLDANWEVRLIRDQLQLQGKLGLRVSLLPLGDVAGVRTEGLRYPLRDEDLPIG
HHCCCEEEEECCCEEEEEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
PARGVSNEFATESAQVSIRSGLLLAMIERELQSGYLA
CCCCCCCHHCCCCCEEEHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLAVIIADAPQADIRAALPLLSSTDLLIAADGGARHALNHGVTPHVIIGDLDSIQPATLE
CEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCCCEEEEECCCCCCHHHHH
IMQARKVEIQRFPAAKNETDLELALLLAAERGADQIRILAALGGRPDMHMANQLLLTHPA
HHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCH
LIGRDVALLDANWEVRLIRDQLQLQGKLGLRVSLLPLGDVAGVRTEGLRYPLRDEDLPIG
HHCCCEEEEECCCEEEEEEHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
PARGVSNEFATESAQVSIRSGLLLAMIERELQSGYLA
CCCCCCCHHCCCCCEEEHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]