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The map label for this gene is accA1 [H]

Identifier: 159899147

GI number: 159899147

Start: 3371691

End: 3373652

Strand: Direct

Name: accA1 [H]

Synonym: Haur_2628

Alternate gene names: 159899147

Gene position: 3371691-3373652 (Clockwise)

Preceding gene: 159899144

Following gene: 159899148

Centisome position: 53.13

GC content: 54.79

Gene sequence:

>1962_bases
GTGACCTACTTCGACTCTTTGTTAATTGCCAATCGGGGCGAAATTGCGGTGCGGGTAATTCGGGCTTGTCGCTCATTGGG
CATCGAAGCAATCGCGGTTTATTCCGATGCCGACGCACGCGCCTTGCATGTGCGCGAGGCTGATCGCGCGATTCGCATCG
GCCCAGCTGCTGCCGCTCAATCGTATTTGAATATCGAAGCAGTGCTAGCCGCTGCCCAACAAACTGGAGCACAGGCGATT
CACCCAGGCTATGGCTTTCTCTCAGAAAATGCCAATTTTGCCCGTGCCTGCCAATCAGCAGGCATTGCCTTCATTGGCCC
GCCCGCCGAAGCAATCGAGGCCATGGGTTCGAAAAGCGCCGCCAAACGCCTCGCCGAATCGGTGGGCGTGCCAACCGTGC
CAGGCTACAACGGCGATGATCAAAGCGAACAACGCTTGTTGGCCGAAGCCGAGCGAATTGGCTTTCCATTGCTGATCAAG
GCTTCAGCTGGTGGCGGCGGCAAAGGCATGCGCAGCGTGCATCGGCTTGCTGAATTTTCAGCGGCCTTGGCAGCAGCGCA
GCGCGAAGCCCTTGCCGCATTTGGCGATCAGCATGTTTTGCTCGAAAAGCTGATTGAACGCCCACGCCATATTGAGTTTC
AAATCCTCGGCGATCAACATGGCACCATGCTGCATCTTGGCGAACGCGAGTGTTCAATTCAACGCCGCCACCAAAAAGTG
CTTGAAGAATCGCCCTCAATTGCATTAACTCCAGCATTACGCGCTACGATGGGCGCGGCGGCGGTGCGTTTGGCGCAAGC
CGTCAATTATTACAATGCTGGCACTCAAGAGTTTATGCTCGATGCCAATGGCGAGTTTTATTTCCTCGAAATGAATACCC
GTTTGCAAGTTGAGCACCCCGTGACCGAGTTGGTGACAGGCTTGGATTTGGTGCAATTGCAAATTGCGATCGCCGCTGGT
CAGCGTTTGCCCTTTGCTCAAGCAGATATTCAGCAAACTGGCCATGCGATTGAAGTGCGCTTGTATGCGGAAGATCCCGT
GCAAATGTTGCCCTCAATCGGCCAACTCAGCAGCTACACGCCGCCCGAAGGCCCAGGCATTCGACTGGATACTGGGGTCA
CAGTTGGCGATCATGTCACGATCAATTATGATCCGATGCTGGCCAAGTTGATCGTGTGGGGCGAGCAGCGTGAGCAAGCG
ATTGCCCGTTTGCGCTATGCCTTGCAGCATTTCGAGGTTGCTGGCGTTACCACTAACATCCCATTGTTGCAAGCGATTAT
CAACACGCCAGCCTACCAAGCCGGAGCCACAACCACCGATTTTCTGCAAACCTATGCAATTAGCGAGCAATTGCAACATC
GTCAGTTGCCACCTAATTTGGCTTTGGCAGCCAGAGCGTTGTTTGATTTAGAGCCTGATCCTGATGCAGCATTAGTTGGC
GACCCTTGGAATGTGCCATGGCGGGCGGCCCACATGCCGCATCAACTACGCTATCAAAGCAACGATCAAACCGTGCCGAT
CAAGGCGCAGCCGCAAGCGCCTCAAGCATGGCTGGTAACGATCAACGACGAGCAACTTGAGATTGTGGTTTTGCGTCGCC
ATCTCAATCGCATGGTTGTGCGGGTTGCCGATCGAATTTATCAATGCCAACTTGAGCAGGATAGCCTCGTTTGGCAAGGC
GTTGGCTATCAGATTCAGCCTGCTGCCGCCCCCAGCCTTGACCAAAATAATGGTCACAAAGGCGATGCGAGCCTTGAAGC
GCCCATGCCAGGCACAATTATCAAACTGCTAGTAGCCGAAGGCGAGCATGTTAGTGCAGGCCAGCCATTGCTGATTATGG
AAGCCATGAAGATGGAGCACACTGTGACCGCGCCCTACGCTGGCACTGTTGCCAAACTGCCCTACCGCCAAGGCCAACAA
GTCAGCGGCGGGGTAGCGCTGGCCGAAATTACCGCTGAGTAA

Upstream 100 bases:

>100_bases
GCTGTATAATGGTAGCAACCACTGATCAACGCTATCAATGGCTGCATTTGTCGTAAATGATGCAAGCATTCGCCTGCATC
GCTAGTGCGGAGTGTCAACG

Downstream 100 bases:

>100_bases
CTATCGCCACAGTAACAGCAAGGGATTGATAAGCATTTAAGTTTATCGATCCCTTATATTTTTAAGCTTGATAATTGGTT
TATCTCCGTTATACTGTAAT

Product: carbamoyl-phosphate synthase L chain ATP-binding

Products: NA

Alternate protein names: Biotin carboxylase; Biotin carboxyl carrier protein; BCCP [H]

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MTYFDSLLIANRGEIAVRVIRACRSLGIEAIAVYSDADARALHVREADRAIRIGPAAAAQSYLNIEAVLAAAQQTGAQAI
HPGYGFLSENANFARACQSAGIAFIGPPAEAIEAMGSKSAAKRLAESVGVPTVPGYNGDDQSEQRLLAEAERIGFPLLIK
ASAGGGGKGMRSVHRLAEFSAALAAAQREALAAFGDQHVLLEKLIERPRHIEFQILGDQHGTMLHLGERECSIQRRHQKV
LEESPSIALTPALRATMGAAAVRLAQAVNYYNAGTQEFMLDANGEFYFLEMNTRLQVEHPVTELVTGLDLVQLQIAIAAG
QRLPFAQADIQQTGHAIEVRLYAEDPVQMLPSIGQLSSYTPPEGPGIRLDTGVTVGDHVTINYDPMLAKLIVWGEQREQA
IARLRYALQHFEVAGVTTNIPLLQAIINTPAYQAGATTTDFLQTYAISEQLQHRQLPPNLALAARALFDLEPDPDAALVG
DPWNVPWRAAHMPHQLRYQSNDQTVPIKAQPQAPQAWLVTINDEQLEIVVLRRHLNRMVVRVADRIYQCQLEQDSLVWQG
VGYQIQPAAAPSLDQNNGHKGDASLEAPMPGTIIKLLVAEGEHVSAGQPLLIMEAMKMEHTVTAPYAGTVAKLPYRQGQQ
VSGGVALAEITAE

Sequences:

>Translated_653_residues
MTYFDSLLIANRGEIAVRVIRACRSLGIEAIAVYSDADARALHVREADRAIRIGPAAAAQSYLNIEAVLAAAQQTGAQAI
HPGYGFLSENANFARACQSAGIAFIGPPAEAIEAMGSKSAAKRLAESVGVPTVPGYNGDDQSEQRLLAEAERIGFPLLIK
ASAGGGGKGMRSVHRLAEFSAALAAAQREALAAFGDQHVLLEKLIERPRHIEFQILGDQHGTMLHLGERECSIQRRHQKV
LEESPSIALTPALRATMGAAAVRLAQAVNYYNAGTQEFMLDANGEFYFLEMNTRLQVEHPVTELVTGLDLVQLQIAIAAG
QRLPFAQADIQQTGHAIEVRLYAEDPVQMLPSIGQLSSYTPPEGPGIRLDTGVTVGDHVTINYDPMLAKLIVWGEQREQA
IARLRYALQHFEVAGVTTNIPLLQAIINTPAYQAGATTTDFLQTYAISEQLQHRQLPPNLALAARALFDLEPDPDAALVG
DPWNVPWRAAHMPHQLRYQSNDQTVPIKAQPQAPQAWLVTINDEQLEIVVLRRHLNRMVVRVADRIYQCQLEQDSLVWQG
VGYQIQPAAAPSLDQNNGHKGDASLEAPMPGTIIKLLVAEGEHVSAGQPLLIMEAMKMEHTVTAPYAGTVAKLPYRQGQQ
VSGGVALAEITAE
>Mature_652_residues
TYFDSLLIANRGEIAVRVIRACRSLGIEAIAVYSDADARALHVREADRAIRIGPAAAAQSYLNIEAVLAAAQQTGAQAIH
PGYGFLSENANFARACQSAGIAFIGPPAEAIEAMGSKSAAKRLAESVGVPTVPGYNGDDQSEQRLLAEAERIGFPLLIKA
SAGGGGKGMRSVHRLAEFSAALAAAQREALAAFGDQHVLLEKLIERPRHIEFQILGDQHGTMLHLGERECSIQRRHQKVL
EESPSIALTPALRATMGAAAVRLAQAVNYYNAGTQEFMLDANGEFYFLEMNTRLQVEHPVTELVTGLDLVQLQIAIAAGQ
RLPFAQADIQQTGHAIEVRLYAEDPVQMLPSIGQLSSYTPPEGPGIRLDTGVTVGDHVTINYDPMLAKLIVWGEQREQAI
ARLRYALQHFEVAGVTTNIPLLQAIINTPAYQAGATTTDFLQTYAISEQLQHRQLPPNLALAARALFDLEPDPDAALVGD
PWNVPWRAAHMPHQLRYQSNDQTVPIKAQPQAPQAWLVTINDEQLEIVVLRRHLNRMVVRVADRIYQCQLEQDSLVWQGV
GYQIQPAAAPSLDQNNGHKGDASLEAPMPGTIIKLLVAEGEHVSAGQPLLIMEAMKMEHTVTAPYAGTVAKLPYRQGQQV
SGGVALAEITAE

Specific function: This protein carries two functions:biotin carboxyl carrier protein and biotin carboxyltransferase [H]

COG id: COG4770

COG function: function code I; Acetyl/propionyl-CoA carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=683, Percent_Identity=41.5812591508053, Blast_Score=520, Evalue=1e-147,
Organism=Homo sapiens, GI295821183, Length=656, Percent_Identity=41.3109756097561, Blast_Score=460, Evalue=1e-129,
Organism=Homo sapiens, GI65506442, Length=442, Percent_Identity=51.5837104072398, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI189095269, Length=445, Percent_Identity=51.2359550561798, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI106049528, Length=443, Percent_Identity=46.0496613995485, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI106049295, Length=443, Percent_Identity=46.0496613995485, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI106049292, Length=443, Percent_Identity=46.0496613995485, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI38679974, Length=718, Percent_Identity=28.4122562674095, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI38679971, Length=718, Percent_Identity=28.4122562674095, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI38679977, Length=718, Percent_Identity=28.4122562674095, Blast_Score=259, Evalue=5e-69,
Organism=Homo sapiens, GI38679967, Length=718, Percent_Identity=28.4122562674095, Blast_Score=259, Evalue=5e-69,
Organism=Homo sapiens, GI38679960, Length=718, Percent_Identity=28.4122562674095, Blast_Score=259, Evalue=5e-69,
Organism=Homo sapiens, GI134142062, Length=725, Percent_Identity=28.1379310344828, Blast_Score=242, Evalue=1e-63,
Organism=Escherichia coli, GI1789654, Length=443, Percent_Identity=48.7584650112867, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI71987519, Length=665, Percent_Identity=41.6541353383459, Blast_Score=502, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17567343, Length=675, Percent_Identity=39.7037037037037, Blast_Score=459, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17562816, Length=472, Percent_Identity=43.2203389830509, Blast_Score=360, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI133931226, Length=683, Percent_Identity=25.9150805270864, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI71997168, Length=646, Percent_Identity=26.625386996904, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=663, Percent_Identity=26.0935143288084, Blast_Score=194, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6319685, Length=444, Percent_Identity=44.8198198198198, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319695, Length=446, Percent_Identity=40.8071748878924, Blast_Score=323, Evalue=7e-89,
Organism=Saccharomyces cerevisiae, GI6321376, Length=447, Percent_Identity=40.9395973154362, Blast_Score=316, Evalue=8e-87,
Organism=Saccharomyces cerevisiae, GI6323863, Length=694, Percent_Identity=28.3861671469741, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6324343, Length=541, Percent_Identity=31.4232902033272, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24651757, Length=678, Percent_Identity=41.4454277286136, Blast_Score=482, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24651759, Length=643, Percent_Identity=40.5909797822706, Blast_Score=436, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24652212, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652210, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652214, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19921944, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652216, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI281363050, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652224, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652222, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652220, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652218, Length=468, Percent_Identity=43.5897435897436, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI161076407, Length=701, Percent_Identity=28.1027104136947, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24586460, Length=701, Percent_Identity=28.1027104136947, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI161076409, Length=701, Percent_Identity=28.1027104136947, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586458, Length=701, Percent_Identity=28.1027104136947, Blast_Score=247, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR001882
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14 [H]

Molecular weight: Translated: 70815; Mature: 70683

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYFDSLLIANRGEIAVRVIRACRSLGIEAIAVYSDADARALHVREADRAIRIGPAAAAQ
CCHHHCEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEECCHHHHH
SYLNIEAVLAAAQQTGAQAIHPGYGFLSENANFARACQSAGIAFIGPPAEAIEAMGSKSA
HHHHHHHHHHHHHHCCCCEECCCCCEECCCCHHHHHHHHCCEEEECCCHHHHHHHCCHHH
AKRLAESVGVPTVPGYNGDDQSEQRLLAEAERIGFPLLIKASAGGGGKGMRSVHRLAEFS
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
AALAAAQREALAAFGDQHVLLEKLIERPRHIEFQILGDQHGTMLHLGERECSIQRRHQKV
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHH
LEESPSIALTPALRATMGAAAVRLAQAVNYYNAGTQEFMLDANGEFYFLEMNTRLQVEHP
HHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCEEEECCC
VTELVTGLDLVQLQIAIAAGQRLPFAQADIQQTGHAIEVRLYAEDPVQMLPSIGQLSSYT
HHHHHCCCHHHEEEEEECCCCCCCCHHHHHHHCCCEEEEEEEECCHHHHCCCHHHHCCCC
PPEGPGIRLDTGVTVGDHVTINYDPMLAKLIVWGEQREQAIARLRYALQHFEVAGVTTNI
CCCCCCEEEECCCEECCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCH
PLLQAIINTPAYQAGATTTDFLQTYAISEQLQHRQLPPNLALAARALFDLEPDPDAALVG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEC
DPWNVPWRAAHMPHQLRYQSNDQTVPIKAQPQAPQAWLVTINDEQLEIVVLRRHLNRMVV
CCCCCCEECCCCCHHEEECCCCCEEEEECCCCCCCEEEEEECCCCEEHHHHHHHHHHHHH
RVADRIYQCQLEQDSLVWQGVGYQIQPAAAPSLDQNNGHKGDASLEAPMPGTIIKLLVAE
HHHHHHHEEECCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEHCC
GEHVSAGQPLLIMEAMKMEHTVTAPYAGTVAKLPYRQGQQVSGGVALAEITAE
CCCCCCCCCEEEHHHHHHCCEECCCCCCCCEECCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TYFDSLLIANRGEIAVRVIRACRSLGIEAIAVYSDADARALHVREADRAIRIGPAAAAQ
CHHHCEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCEEEECCHHHHH
SYLNIEAVLAAAQQTGAQAIHPGYGFLSENANFARACQSAGIAFIGPPAEAIEAMGSKSA
HHHHHHHHHHHHHHCCCCEECCCCCEECCCCHHHHHHHHCCEEEECCCHHHHHHHCCHHH
AKRLAESVGVPTVPGYNGDDQSEQRLLAEAERIGFPLLIKASAGGGGKGMRSVHRLAEFS
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
AALAAAQREALAAFGDQHVLLEKLIERPRHIEFQILGDQHGTMLHLGERECSIQRRHQKV
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHH
LEESPSIALTPALRATMGAAAVRLAQAVNYYNAGTQEFMLDANGEFYFLEMNTRLQVEHP
HHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCEEEECCC
VTELVTGLDLVQLQIAIAAGQRLPFAQADIQQTGHAIEVRLYAEDPVQMLPSIGQLSSYT
HHHHHCCCHHHEEEEEECCCCCCCCHHHHHHHCCCEEEEEEEECCHHHHCCCHHHHCCCC
PPEGPGIRLDTGVTVGDHVTINYDPMLAKLIVWGEQREQAIARLRYALQHFEVAGVTTNI
CCCCCCEEEECCCEECCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCH
PLLQAIINTPAYQAGATTTDFLQTYAISEQLQHRQLPPNLALAARALFDLEPDPDAALVG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEC
DPWNVPWRAAHMPHQLRYQSNDQTVPIKAQPQAPQAWLVTINDEQLEIVVLRRHLNRMVV
CCCCCCEECCCCCHHEEECCCCCEEEEECCCCCCCEEEEEECCCCEEHHHHHHHHHHHHH
RVADRIYQCQLEQDSLVWQGVGYQIQPAAAPSLDQNNGHKGDASLEAPMPGTIIKLLVAE
HHHHHHHEEECCCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEHCC
GEHVSAGQPLLIMEAMKMEHTVTAPYAGTVAKLPYRQGQQVSGGVALAEITAE
CCCCCCCCCEEEHHHHHHCCEECCCCCCCCEECCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]