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The map label for this gene is atoS [H]

Identifier: 159898888

GI number: 159898888

Start: 3014920

End: 3016239

Strand: Reverse

Name: atoS [H]

Synonym: Haur_2367

Alternate gene names: 159898888

Gene position: 3016239-3014920 (Counterclockwise)

Preceding gene: 159898890

Following gene: 159898887

Centisome position: 47.53

GC content: 51.14

Gene sequence:

>1320_bases
ATGCTTCAATCGATTAAACAGCGCTATTGGCTGTGGTTTGTGCTTAGCAGCGAGTTGATCATCACGGCGCTGCATTATCT
GACCAGTGCTCATCTATTGCCCTACCACTCGATTTATCGCAGTTTGTATTATGTGCCTGTTGGTGTGGCGGCGGTGATCT
GGGGTCGTTGGGCGGGCATTGGCTTGGCGCTGTTCACGGCGCTTGTCTATTTGCCGCATGCCCATTGGCTCGATGCGCAT
GCGGCCAACAGCTTGCTTGATAATGGCCTCGAAATGGCGACGTTGGTGCTGGTTGCCGCTTTGGTTGGCACATTGGCCGA
GCGTGAACAACAGGCCCATAGTCGGGCCGAAGCCTTGCATGTGTATATTAACGATGTATTGACAAGTTTGCCTGTCGGCG
TAGCAACCATCGAGCAGCAACAATTGAAATTGCAAAATCCAACTGCCCAAACCTTATTACAGCCAAGGCCAGCTCTCGTG
CAACTGCCCCAAACCAATGGCTACAGCGAAATCCAAATCAATCAAATTGCCTTGGCAGTACGTCGCTCTGATTTGCATAA
TCTGCAAGGCCAGCCGATTGGCGCAGTTTTGGTGTTTGAAGATATTCGCGAACAACAAGCGATCGCCGAGCGGATTCGTC
AGGCTGAACGGATGGCGGCTTTGGGGCAGTTGGCTGGTGGTTTGGCGCACGAGGCGCGTAATCCTTTGGGCGTAGTGCGA
GCCACCAGCCAACTGCTGGGCACTAAATTGACCCAACAACCAAATTTGGCAAGCTATACCAGCGTCATTAATAGCGAGGT
TGATCGCTTGGATCGGCTGATTAGTTCGTTGTTGGATTATGCCCATCCCCAAGCGTTACAGCGCCAGCCTTTGGCAATTA
ACCAATTATTAGTTGAATTTGTGGCTACCTGTCAGCCTTTGGCGGCTGAATATGGGGTTGATCTTCATCTAACCATCACC
GATGATCAATTATGGGTTGAAGCTGATCACGATGCGATCTGGCAAATTCTATTAAATCTGTTGTTGAACGCATTGCAAGC
GAGCCAAGCTGGCCAAATTATTCAGGTTCAGAGTTTGGCTGTGGCCCAACAGCTTGAAATTCGTATCCAAGATCAGGGCA
AAGGCATTGATCCAGCGATTCGTGAGCGAATTTTCGATCCATTTTTTACAACCCGCGACGATGGCACGGGTATGGGTTTG
GCCTTGGTGGCACGCAGCGTAGCTGAACATAGCGGCTCAATTCGGCTTGAGCCTGCGCCTGATCGCGGCACCTTAGCCCG
TTTGCGCTTGCCACTTGTGAACCAAGGAGCTGAGCAATGA

Upstream 100 bases:

>100_bases
GGTTTTAGCAATCAAATTATCGGAATTCTATAAAAAAATTGTTTGCTGAACAGAACAAACTTACAATAGAAGCAACAACC
TTTAAACGACGAGGCTGATC

Downstream 100 bases:

>100_bases
CCAAACGCCTCTTAGTTATCGACGATGAAGCCAATTTACGCTGGGTGCTTAGCGAGGCCTTGAGCGACCAAGGCTACGAC
GTAGTGGTGGCCGCGAATGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MLQSIKQRYWLWFVLSSELIITALHYLTSAHLLPYHSIYRSLYYVPVGVAAVIWGRWAGIGLALFTALVYLPHAHWLDAH
AANSLLDNGLEMATLVLVAALVGTLAEREQQAHSRAEALHVYINDVLTSLPVGVATIEQQQLKLQNPTAQTLLQPRPALV
QLPQTNGYSEIQINQIALAVRRSDLHNLQGQPIGAVLVFEDIREQQAIAERIRQAERMAALGQLAGGLAHEARNPLGVVR
ATSQLLGTKLTQQPNLASYTSVINSEVDRLDRLISSLLDYAHPQALQRQPLAINQLLVEFVATCQPLAAEYGVDLHLTIT
DDQLWVEADHDAIWQILLNLLLNALQASQAGQIIQVQSLAVAQQLEIRIQDQGKGIDPAIRERIFDPFFTTRDDGTGMGL
ALVARSVAEHSGSIRLEPAPDRGTLARLRLPLVNQGAEQ

Sequences:

>Translated_439_residues
MLQSIKQRYWLWFVLSSELIITALHYLTSAHLLPYHSIYRSLYYVPVGVAAVIWGRWAGIGLALFTALVYLPHAHWLDAH
AANSLLDNGLEMATLVLVAALVGTLAEREQQAHSRAEALHVYINDVLTSLPVGVATIEQQQLKLQNPTAQTLLQPRPALV
QLPQTNGYSEIQINQIALAVRRSDLHNLQGQPIGAVLVFEDIREQQAIAERIRQAERMAALGQLAGGLAHEARNPLGVVR
ATSQLLGTKLTQQPNLASYTSVINSEVDRLDRLISSLLDYAHPQALQRQPLAINQLLVEFVATCQPLAAEYGVDLHLTIT
DDQLWVEADHDAIWQILLNLLLNALQASQAGQIIQVQSLAVAQQLEIRIQDQGKGIDPAIRERIFDPFFTTRDDGTGMGL
ALVARSVAEHSGSIRLEPAPDRGTLARLRLPLVNQGAEQ
>Mature_439_residues
MLQSIKQRYWLWFVLSSELIITALHYLTSAHLLPYHSIYRSLYYVPVGVAAVIWGRWAGIGLALFTALVYLPHAHWLDAH
AANSLLDNGLEMATLVLVAALVGTLAEREQQAHSRAEALHVYINDVLTSLPVGVATIEQQQLKLQNPTAQTLLQPRPALV
QLPQTNGYSEIQINQIALAVRRSDLHNLQGQPIGAVLVFEDIREQQAIAERIRQAERMAALGQLAGGLAHEARNPLGVVR
ATSQLLGTKLTQQPNLASYTSVINSEVDRLDRLISSLLDYAHPQALQRQPLAINQLLVEFVATCQPLAAEYGVDLHLTIT
DDQLWVEADHDAIWQILLNLLLNALQASQAGQIIQVQSLAVAQQLEIRIQDQGKGIDPAIRERIFDPFFTTRDDGTGMGL
ALVARSVAEHSGSIRLEPAPDRGTLARLRLPLVNQGAEQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=37.8787878787879, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1790436, Length=308, Percent_Identity=30.5194805194805, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1790300, Length=224, Percent_Identity=34.375, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789149, Length=231, Percent_Identity=29.4372294372294, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=30, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=27.0491803278689, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081816, Length=295, Percent_Identity=27.4576271186441, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=25.6637168141593, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=216, Percent_Identity=26.3888888888889, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=25, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48393; Mature: 48393

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQSIKQRYWLWFVLSSELIITALHYLTSAHLLPYHSIYRSLYYVPVGVAAVIWGRWAGI
CCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLALFTALVYLPHAHWLDAHAANSLLDNGLEMATLVLVAALVGTLAEREQQAHSRAEALH
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYINDVLTSLPVGVATIEQQQLKLQNPTAQTLLQPRPALVQLPQTNGYSEIQINQIALAV
HHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHH
RRSDLHNLQGQPIGAVLVFEDIREQQAIAERIRQAERMAALGQLAGGLAHEARNPLGVVR
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ATSQLLGTKLTQQPNLASYTSVINSEVDRLDRLISSLLDYAHPQALQRQPLAINQLLVEF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHH
VATCQPLAAEYGVDLHLTITDDQLWVEADHDAIWQILLNLLLNALQASQAGQIIQVQSLA
HHHHHHHHHHCCCEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
VAQQLEIRIQDQGKGIDPAIRERIFDPFFTTRDDGTGMGLALVARSVAEHSGSIRLEPAP
HHHHHHEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCC
DRGTLARLRLPLVNQGAEQ
CCCCHHHEECCHHCCCCCC
>Mature Secondary Structure
MLQSIKQRYWLWFVLSSELIITALHYLTSAHLLPYHSIYRSLYYVPVGVAAVIWGRWAGI
CCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLALFTALVYLPHAHWLDAHAANSLLDNGLEMATLVLVAALVGTLAEREQQAHSRAEALH
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYINDVLTSLPVGVATIEQQQLKLQNPTAQTLLQPRPALVQLPQTNGYSEIQINQIALAV
HHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHH
RRSDLHNLQGQPIGAVLVFEDIREQQAIAERIRQAERMAALGQLAGGLAHEARNPLGVVR
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ATSQLLGTKLTQQPNLASYTSVINSEVDRLDRLISSLLDYAHPQALQRQPLAINQLLVEF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHH
VATCQPLAAEYGVDLHLTITDDQLWVEADHDAIWQILLNLLLNALQASQAGQIIQVQSLA
HHHHHHHHHHCCCEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
VAQQLEIRIQDQGKGIDPAIRERIFDPFFTTRDDGTGMGLALVARSVAEHSGSIRLEPAP
HHHHHHEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCC
DRGTLARLRLPLVNQGAEQ
CCCCHHHEECCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]