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The map label for this gene is mtlR [H]

Identifier: 159898049

GI number: 159898049

Start: 1776332

End: 1777873

Strand: Direct

Name: mtlR [H]

Synonym: Haur_1524

Alternate gene names: 159898049

Gene position: 1776332-1777873 (Clockwise)

Preceding gene: 159898048

Following gene: 159898050

Centisome position: 27.99

GC content: 52.33

Gene sequence:

>1542_bases
ATGCTGTCGCTGACGACTGCTCAACGTGATCTGTTGTATCTGTTGCTTACCACTGAGACTCCAATCGGGGCTGCGGCACT
CGGTCAGTGTCTCCATCTCACACCACGCCAAGTTTCCTATAGTTTACGGAGTATTAAGCTGTGGTTGGCTCGTCGCCATG
CCAGTTTGCGCCAAGTGCCTGGGGTTGGCATGCAGCTGATCTGCTCGGCCCAGCAACGTGAACGGCTTTATGCTGAGCTA
GAATCGCATGCCAAATTTCAATTAATTCTCACGCCCGAACAACGTGGTCAGCTTTTGGCCTTAGTGCTGTTGATTACCCC
CGAACCCTTGACCCTCAACCAACTCCAGCAAGATTTAGCAGTTGCTCGCACGACGGTGCTTAAAGATCTCGATGTCATGG
AGATTTGGTTGGCCAGTTTTGGTTTGCAAGTGGTGCGGCGACAACATCGCGGCTGCTGGATCGAAGGCGCTGAGTTGGCG
AAACGCCAAGCCTTGGCAGCCTTGTTATGGGGCGATGTGCCCTTTAGTTTGCCAATTATCAGCGTGCAAGCGGGCCTTGG
CTTTGATTTTGTGTTGCAACAAGATGCAGCCCTCTTACCGATTATTCAACGGGTCAATAGCTTTTTGCAGGAGCTTGATC
TGCCTAAAGCCCAACAGCAGGCGATCTGGGCCGAAGCTGCCTTGAATGCGCGGTTTAGCGATCAGGCAATTAGTTTGCTG
GCTTTGGCCTTGGCTTTGCAACAGCAACGGATCAATGCTCAACAGTATCTCCATTGGCATCCCGAAACATTACATTGGCT
GGAACAGCAGTTGGTTTGGTCAGTTGCTACGCAATTTGAGCAACATTATGGTTTGCAGGCCAGTGCAACGATCGATCTTG
CTGAAATTGCTGGTGTAGCCTTGCAATTGGTGTGTGCTGCCCGCGAACGGCCATGGCCCAATCAGCATGAGACCGATCAC
GTAACCGTTCGGTTGATCAATGCACTGATTGATTTGATTGCCAGTAGCTACGATGTCGCAGAGCTTGCCAACGATCAGCT
TTTGGGTGATGGTTTGGCCGCCTTGATTCCGCCAGCCTGCAATCGCCAGCGCTTTGGTTTGTGGATTCCGACCCATCAAT
CCAGCGAAACGCAGAGTGAACGTTATGCAACTGAGCGGCGGGTGGCCGATTTAATTGATCGCAAGCTGCTGGCAACGATT
GGTGTAGCTTTGCCGATTGATGCCCGTGATGAGCTGATTTTGTTGTTGCGGGCAGCGGTGGTGCGGGCGCGGCCTGTGCA
AACCCGCAATATTCTGGTGGTTTGCCCGAGCGGCATGGCCACAACTCAACTGTTGGTAGCACGGCTCAAAGCACGGTTTC
CCAAACTGGGTATTTTTGAAGTGCTCTCGATGCGCGAGCTTTCGGCAGAACGTTTAGCCAATGCCGATTTGGTGATTACG
ACTGCGCCTTTAGCATTGGCTAGTGTGCCAATTGATGTCATCCAAGTGCATCCAATGCTGCACCCAGAAGATATTGCGGC
GCTGACCCAGTGGATGGTTTAG

Upstream 100 bases:

>100_bases
CCATGATTTAGCGCTTGACAATGGGCTAAAACGCGGCTAGCATACATTAACTCTCTGATTGTAGGGAACCTATTTCGCTC
TACGACTATGGGGTAAACGT

Downstream 100 bases:

>100_bases
CCTGCTAAATCATCGCATTTTGTCGTAATAGCGCAACCAAAAGACAGATTAATAAAATGGGTTTTATGGCTTGACAATGG
CCTAAAACGCTTGTACGTTA

Product: transcriptional antiterminator, BglG

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MLSLTTAQRDLLYLLLTTETPIGAAALGQCLHLTPRQVSYSLRSIKLWLARRHASLRQVPGVGMQLICSAQQRERLYAEL
ESHAKFQLILTPEQRGQLLALVLLITPEPLTLNQLQQDLAVARTTVLKDLDVMEIWLASFGLQVVRRQHRGCWIEGAELA
KRQALAALLWGDVPFSLPIISVQAGLGFDFVLQQDAALLPIIQRVNSFLQELDLPKAQQQAIWAEAALNARFSDQAISLL
ALALALQQQRINAQQYLHWHPETLHWLEQQLVWSVATQFEQHYGLQASATIDLAEIAGVALQLVCAARERPWPNQHETDH
VTVRLINALIDLIASSYDVAELANDQLLGDGLAALIPPACNRQRFGLWIPTHQSSETQSERYATERRVADLIDRKLLATI
GVALPIDARDELILLLRAAVVRARPVQTRNILVVCPSGMATTQLLVARLKARFPKLGIFEVLSMRELSAERLANADLVIT
TAPLALASVPIDVIQVHPMLHPEDIAALTQWMV

Sequences:

>Translated_513_residues
MLSLTTAQRDLLYLLLTTETPIGAAALGQCLHLTPRQVSYSLRSIKLWLARRHASLRQVPGVGMQLICSAQQRERLYAEL
ESHAKFQLILTPEQRGQLLALVLLITPEPLTLNQLQQDLAVARTTVLKDLDVMEIWLASFGLQVVRRQHRGCWIEGAELA
KRQALAALLWGDVPFSLPIISVQAGLGFDFVLQQDAALLPIIQRVNSFLQELDLPKAQQQAIWAEAALNARFSDQAISLL
ALALALQQQRINAQQYLHWHPETLHWLEQQLVWSVATQFEQHYGLQASATIDLAEIAGVALQLVCAARERPWPNQHETDH
VTVRLINALIDLIASSYDVAELANDQLLGDGLAALIPPACNRQRFGLWIPTHQSSETQSERYATERRVADLIDRKLLATI
GVALPIDARDELILLLRAAVVRARPVQTRNILVVCPSGMATTQLLVARLKARFPKLGIFEVLSMRELSAERLANADLVIT
TAPLALASVPIDVIQVHPMLHPEDIAALTQWMV
>Mature_513_residues
MLSLTTAQRDLLYLLLTTETPIGAAALGQCLHLTPRQVSYSLRSIKLWLARRHASLRQVPGVGMQLICSAQQRERLYAEL
ESHAKFQLILTPEQRGQLLALVLLITPEPLTLNQLQQDLAVARTTVLKDLDVMEIWLASFGLQVVRRQHRGCWIEGAELA
KRQALAALLWGDVPFSLPIISVQAGLGFDFVLQQDAALLPIIQRVNSFLQELDLPKAQQQAIWAEAALNARFSDQAISLL
ALALALQQQRINAQQYLHWHPETLHWLEQQLVWSVATQFEQHYGLQASATIDLAEIAGVALQLVCAARERPWPNQHETDH
VTVRLINALIDLIASSYDVAELANDQLLGDGLAALIPPACNRQRFGLWIPTHQSSETQSERYATERRVADLIDRKLLATI
GVALPIDARDELILLLRAAVVRARPVQTRNILVVCPSGMATTQLLVARLKARFPKLGIFEVLSMRELSAERLANADLVIT
TAPLALASVPIDVIQVHPMLHPEDIAALTQWMV

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57097; Mature: 57097

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLTTAQRDLLYLLLTTETPIGAAALGQCLHLTPRQVSYSLRSIKLWLARRHASLRQVP
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GVGMQLICSAQQRERLYAELESHAKFQLILTPEQRGQLLALVLLITPEPLTLNQLQQDLA
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHH
VARTTVLKDLDVMEIWLASFGLQVVRRQHRGCWIEGAELAKRQALAALLWGDVPFSLPII
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEE
SVQAGLGFDFVLQQDAALLPIIQRVNSFLQELDLPKAQQQAIWAEAALNARFSDQAISLL
EEECCCCEEEHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
ALALALQQQRINAQQYLHWHPETLHWLEQQLVWSVATQFEQHYGLQASATIDLAEIAGVA
HHHHHHHHHHCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHH
LQLVCAARERPWPNQHETDHVTVRLINALIDLIASSYDVAELANDQLLGDGLAALIPPAC
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHCCCHHHHCCCCC
NRQRFGLWIPTHQSSETQSERYATERRVADLIDRKLLATIGVALPIDARDELILLLRAAV
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VRARPVQTRNILVVCPSGMATTQLLVARLKARFPKLGIFEVLSMRELSAERLANADLVIT
HHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
TAPLALASVPIDVIQVHPMLHPEDIAALTQWMV
ECCHHHHHCCEEHEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLSLTTAQRDLLYLLLTTETPIGAAALGQCLHLTPRQVSYSLRSIKLWLARRHASLRQVP
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GVGMQLICSAQQRERLYAELESHAKFQLILTPEQRGQLLALVLLITPEPLTLNQLQQDLA
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHH
VARTTVLKDLDVMEIWLASFGLQVVRRQHRGCWIEGAELAKRQALAALLWGDVPFSLPII
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEE
SVQAGLGFDFVLQQDAALLPIIQRVNSFLQELDLPKAQQQAIWAEAALNARFSDQAISLL
EEECCCCEEEHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
ALALALQQQRINAQQYLHWHPETLHWLEQQLVWSVATQFEQHYGLQASATIDLAEIAGVA
HHHHHHHHHHCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHH
LQLVCAARERPWPNQHETDHVTVRLINALIDLIASSYDVAELANDQLLGDGLAALIPPAC
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHCCCHHHHCCCCC
NRQRFGLWIPTHQSSETQSERYATERRVADLIDRKLLATIGVALPIDARDELILLLRAAV
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VRARPVQTRNILVVCPSGMATTQLLVARLKARFPKLGIFEVLSMRELSAERLANADLVIT
HHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
TAPLALASVPIDVIQVHPMLHPEDIAALTQWMV
ECCHHHHHCCEEHEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]