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The map label for this gene is rsbRA [H]

Identifier: 159897799

GI number: 159897799

Start: 1481599

End: 1482576

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_1270

Alternate gene names: 159897799

Gene position: 1481599-1482576 (Clockwise)

Preceding gene: 159897798

Following gene: 159897801

Centisome position: 23.34

GC content: 50.72

Gene sequence:

>978_bases
ATGCTCAATCGTGAAATCGAACTTGCCATCCTCTATGAAATTTCATCGCTGCCTTTAACGCTCACAACGATTGAGGCAAC
CTTGGATGTTGCGCTGGATAAAGTAACCAGGTTGTTTGCCTGCGAAGTTGCGGTCTGCTATGTGCTTGAATCACCATTAA
CCTTGGTGGCAAAGGCCTGTCGTGGGGTGCGGCTCAAGCGTGTTTTGCCAAGCATCGAGCTTGAGCAACCCCAGCAACTT
GGCGATTATAGCCATGCTTGGCAGGCTGGCGAACCCTTGCCATGGCCCGCCGACCCCTTACAAAGCCAGTACCCGATGCA
AGCAGCAATTGGCCTGCCAATTTGGAACGAAGGCACGTTGCTGGGTTGGATCTATGCTGGGCGTTTGAAGGGCCAAACAT
TCAGCACCGTCGAAGTCTCGTTATTTAATATTTTTGCCAACCGGATTGGCAGCGCCTTGGCGATTACGCTTGGGCGCTTG
CGCGATCAGCAGCAACAGCGCGATTTAGCTCAAGCCAATGCCCAACTTGAGCAAACCCTAACCCGCTTGACCGATGTTTA
TCAGCAACAAGAACAACTATTGCAAACCATTCGCGAGCTTTCGGCTCCGTTATTGCAAATTGCCGATGCTGTGATGTTAC
TGCCCTTAATTGGTACAGTTGACGAAGAACGAGCCAGCCAAATCACCGCCAATGTGCTGATGACGATCAGCCAAAATCAT
GCGACAGTCTGTATTATTGACATTACGGGGATTGCCGCGCTGGATTATGTGGCAGCCAATAGTTTGTTGCAGTTGGCGCA
ATCGGCGCGTTTGCTGGGAACTCAAATTATCTTGTGTGGCATTTCGCCCGATGTCGCCCAAATTTTGGTCTCGTTGGGCA
TGAATTTGGCCTGCACCCGCACCACCAACGATTTACAACATGCCCTACGTTTAGCCTTCCAACTAGCTGGATCGCGTGAT
CATCACATGGTTGCTTAA

Upstream 100 bases:

>100_bases
GAAATTGCTGCTGCGGAAACAGGCGGAGCGCTGTTTCATAACAAAACCGTTGTTGTGTACGCTATTGGTCAGGCCTGACC
ATTGAACGGATGAACCTTGT

Downstream 100 bases:

>100_bases
ATAATTAATGGGTGAACTCAACCCACTGAGCGCACCCATTTTGCGTCCCTCGGCCTACCGTTGCCTAATCTGGCTCCCAG
ACTGCCTCGCCATCCATTAC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLNREIELAILYEISSLPLTLTTIEATLDVALDKVTRLFACEVAVCYVLESPLTLVAKACRGVRLKRVLPSIELEQPQQL
GDYSHAWQAGEPLPWPADPLQSQYPMQAAIGLPIWNEGTLLGWIYAGRLKGQTFSTVEVSLFNIFANRIGSALAITLGRL
RDQQQQRDLAQANAQLEQTLTRLTDVYQQQEQLLQTIRELSAPLLQIADAVMLLPLIGTVDEERASQITANVLMTISQNH
ATVCIIDITGIAALDYVAANSLLQLAQSARLLGTQIILCGISPDVAQILVSLGMNLACTRTTNDLQHALRLAFQLAGSRD
HHMVA

Sequences:

>Translated_325_residues
MLNREIELAILYEISSLPLTLTTIEATLDVALDKVTRLFACEVAVCYVLESPLTLVAKACRGVRLKRVLPSIELEQPQQL
GDYSHAWQAGEPLPWPADPLQSQYPMQAAIGLPIWNEGTLLGWIYAGRLKGQTFSTVEVSLFNIFANRIGSALAITLGRL
RDQQQQRDLAQANAQLEQTLTRLTDVYQQQEQLLQTIRELSAPLLQIADAVMLLPLIGTVDEERASQITANVLMTISQNH
ATVCIIDITGIAALDYVAANSLLQLAQSARLLGTQIILCGISPDVAQILVSLGMNLACTRTTNDLQHALRLAFQLAGSRD
HHMVA
>Mature_325_residues
MLNREIELAILYEISSLPLTLTTIEATLDVALDKVTRLFACEVAVCYVLESPLTLVAKACRGVRLKRVLPSIELEQPQQL
GDYSHAWQAGEPLPWPADPLQSQYPMQAAIGLPIWNEGTLLGWIYAGRLKGQTFSTVEVSLFNIFANRIGSALAITLGRL
RDQQQQRDLAQANAQLEQTLTRLTDVYQQQEQLLQTIRELSAPLLQIADAVMLLPLIGTVDEERASQITANVLMTISQNH
ATVCIIDITGIAALDYVAANSLLQLAQSARLLGTQIILCGISPDVAQILVSLGMNLACTRTTNDLQHALRLAFQLAGSRD
HHMVA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 35643; Mature: 35643

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNREIELAILYEISSLPLTLTTIEATLDVALDKVTRLFACEVAVCYVLESPLTLVAKAC
CCCCEEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
RGVRLKRVLPSIELEQPQQLGDYSHAWQAGEPLPWPADPLQSQYPMQAAIGLPIWNEGTL
CCCCHHHHCCCCCCCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCE
LGWIYAGRLKGQTFSTVEVSLFNIFANRIGSALAITLGRLRDQQQQRDLAQANAQLEQTL
EEEEEECCCCCCEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLTDVYQQQEQLLQTIRELSAPLLQIADAVMLLPLIGTVDEERASQITANVLMTISQNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCC
ATVCIIDITGIAALDYVAANSLLQLAQSARLLGTQIILCGISPDVAQILVSLGMNLACTR
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCEEEEC
TTNDLQHALRLAFQLAGSRDHHMVA
CHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLNREIELAILYEISSLPLTLTTIEATLDVALDKVTRLFACEVAVCYVLESPLTLVAKAC
CCCCEEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
RGVRLKRVLPSIELEQPQQLGDYSHAWQAGEPLPWPADPLQSQYPMQAAIGLPIWNEGTL
CCCCHHHHCCCCCCCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCE
LGWIYAGRLKGQTFSTVEVSLFNIFANRIGSALAITLGRLRDQQQQRDLAQANAQLEQTL
EEEEEECCCCCCEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLTDVYQQQEQLLQTIRELSAPLLQIADAVMLLPLIGTVDEERASQITANVLMTISQNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCC
ATVCIIDITGIAALDYVAANSLLQLAQSARLLGTQIILCGISPDVAQILVSLGMNLACTR
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCEEEEC
TTNDLQHALRLAFQLAGSRDHHMVA
CHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]