Click here to switch to the map view.

The map label for this gene is hutI

Identifier: 159897136

GI number: 159897136

Start: 699118

End: 700401

Strand: Reverse

Name: hutI

Synonym: Haur_0607

Alternate gene names: 159897136

Gene position: 700401-699118 (Counterclockwise)

Preceding gene: 159897147

Following gene: 159897123

Centisome position: 11.04

GC content: 52.65

Gene sequence:

>1284_bases
ATGCCCCACGCTGATCAATTAATTACCAATATAGGTCGCTTGGTTACTGGCCCGCAAGCACCTTTACGCGGCCAACAGCT
GGCCCAATTAACCGCTATCGACCAAGCTGTTGTTGCTGTCCAAGCAGGCAACATCGTGGCACTTGGCAGTCAGGCCGAGC
TTAGCGCTTGGACTGCCGATCAAACAATCGATGCAGGTGGTTATTTGGCAATCCCAGGCTTTGTCGATCCCCACACCCAC
GCTTGTTATGCAGGCGATCGCGCCCATGAGTTCGAATTACGAATCAAAGGCGCAAGCTATAGCGAATTAATGGCGGCTGG
TGGAGGAATTATGTCAACAGTTCATGCCACACGAGCAGCCAGTAAAGCCGAATTAGTTGCCCAAACCCGCCCACGGCTTG
ATCAATTATTGGCCCATGGCACAACTACCGTCGAAATCAAAAGTGGCTATGGGCTTGATACCGCTACCGAATTAACCATG
CTCGAAGCGATCGCTGAGCTAGCCCAAACTCATCCAATTGGCATCGTGCCGACCTTTATGGGGGCACACGCCATTCCCGC
CGAATATCGCGACAATCCAGAAGCGTTTGTAGATTTGGTGGTTGATGAGATGTTGCCTGCAGTAGCAGCTTGGTGGCAAC
AGCAAACAATCTGGCAAGAACCCTTGGCTTGCGACATTTTCTGCGAAAATGGAGCCTTTTCAGTTGCCCAAAGCCAACGT
ATTTTGGTTAAGGCCAAAGCATTGGGCTTTCGCTTGAAATTGCATGTCGATGAGTTTGAGCCGTTGGGTGGCACGCCGCT
AGCGGTCGAACTAGGGGCAATCTCGGTTGATCACTTGGTCGCCACGCCGCCCGAACATATCGCGATCTTGGCAAATTCAG
AAACCGTGGGCGTTTCGTTGCCTGGCACGCCGTTTGGTCTGGGCAAGAGTCAATTCAGCCCAGCTCGCAGTTTAATCGAA
GCGAACGGAATTTTGGCCCTAGCCACCGATTGTAATCCAGGCACCAGCCCTTGTGAATCGATGCCGATGGCAATTGCCAT
TGCTTGTCGCTATTTACGGCTGACTCCAGCCGAGGCCTTGAACGCGGCCACGGTTAATTCAGCGTTTGCAATTCGCCAGC
ATGAGCGCGTTGGTAGCTTAGCAGTTGGCATGCAAGCTGATCTGGCCTTGCTCAACCTGCCCGACGAACGCCATATCGGC
TATAAGTTTGGCACAAATCCAGTCGCCATCGTGATCAAAACAGGTAGGGTGGTCCGTCGGAACCAACTTCACGCTGATCG
CTAA

Upstream 100 bases:

>100_bases
CCTCCTTATTGGTAAGGCTATTATAGCAGATAAGCCGACCTTTTCAGCTGTGGTAGGATACAGCGGTTATCGTTGCTCGC
AGTTAACTCAAGGAGGAGTT

Downstream 100 bases:

>100_bases
ATGGTTGCTCGACCCATGGCAACTTGACAATAAAAGTTGAGCCATGGCCTAACTCGCTGGTCACTTCAATATCGCCGCCC
ATTAATTTGCACAGATTACG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MPHADQLITNIGRLVTGPQAPLRGQQLAQLTAIDQAVVAVQAGNIVALGSQAELSAWTADQTIDAGGYLAIPGFVDPHTH
ACYAGDRAHEFELRIKGASYSELMAAGGGIMSTVHATRAASKAELVAQTRPRLDQLLAHGTTTVEIKSGYGLDTATELTM
LEAIAELAQTHPIGIVPTFMGAHAIPAEYRDNPEAFVDLVVDEMLPAVAAWWQQQTIWQEPLACDIFCENGAFSVAQSQR
ILVKAKALGFRLKLHVDEFEPLGGTPLAVELGAISVDHLVATPPEHIAILANSETVGVSLPGTPFGLGKSQFSPARSLIE
ANGILALATDCNPGTSPCESMPMAIAIACRYLRLTPAEALNAATVNSAFAIRQHERVGSLAVGMQADLALLNLPDERHIG
YKFGTNPVAIVIKTGRVVRRNQLHADR

Sequences:

>Translated_427_residues
MPHADQLITNIGRLVTGPQAPLRGQQLAQLTAIDQAVVAVQAGNIVALGSQAELSAWTADQTIDAGGYLAIPGFVDPHTH
ACYAGDRAHEFELRIKGASYSELMAAGGGIMSTVHATRAASKAELVAQTRPRLDQLLAHGTTTVEIKSGYGLDTATELTM
LEAIAELAQTHPIGIVPTFMGAHAIPAEYRDNPEAFVDLVVDEMLPAVAAWWQQQTIWQEPLACDIFCENGAFSVAQSQR
ILVKAKALGFRLKLHVDEFEPLGGTPLAVELGAISVDHLVATPPEHIAILANSETVGVSLPGTPFGLGKSQFSPARSLIE
ANGILALATDCNPGTSPCESMPMAIAIACRYLRLTPAEALNAATVNSAFAIRQHERVGSLAVGMQADLALLNLPDERHIG
YKFGTNPVAIVIKTGRVVRRNQLHADR
>Mature_426_residues
PHADQLITNIGRLVTGPQAPLRGQQLAQLTAIDQAVVAVQAGNIVALGSQAELSAWTADQTIDAGGYLAIPGFVDPHTHA
CYAGDRAHEFELRIKGASYSELMAAGGGIMSTVHATRAASKAELVAQTRPRLDQLLAHGTTTVEIKSGYGLDTATELTML
EAIAELAQTHPIGIVPTFMGAHAIPAEYRDNPEAFVDLVVDEMLPAVAAWWQQQTIWQEPLACDIFCENGAFSVAQSQRI
LVKAKALGFRLKLHVDEFEPLGGTPLAVELGAISVDHLVATPPEHIAILANSETVGVSLPGTPFGLGKSQFSPARSLIEA
NGILALATDCNPGTSPCESMPMAIAIACRYLRLTPAEALNAATVNSAFAIRQHERVGSLAVGMQADLALLNLPDERHIGY
KFGTNPVAIVIKTGRVVRRNQLHADR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=391, Percent_Identity=37.0843989769821, Blast_Score=230, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17555004, Length=376, Percent_Identity=36.1702127659575, Blast_Score=227, Evalue=9e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_HERA2 (A9AW17)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001543383.1
- ProteinModelPortal:   A9AW17
- SMR:   A9AW17
- GeneID:   5732505
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_0607
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- BioCyc:   HAUR316274:HAUR_0607-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1

EC number: =3.5.2.7

Molecular weight: Translated: 45338; Mature: 45207

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: BINDING 87-87 BINDING 100-100 BINDING 150-150 BINDING 183-183 BINDING 258-258

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHADQLITNIGRLVTGPQAPLRGQQLAQLTAIDQAVVAVQAGNIVALGSQAELSAWTAD
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEEECCCEEEECCCCCCEEECCC
QTIDAGGYLAIPGFVDPHTHACYAGDRAHEFELRIKGASYSELMAAGGGIMSTVHATRAA
CEECCCCEEEECCCCCCCCCEEECCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHH
SKAELVAQTRPRLDQLLAHGTTTVEIKSGYGLDTATELTMLEAIAELAQTHPIGIVPTFM
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHH
GAHAIPAEYRDNPEAFVDLVVDEMLPAVAAWWQQQTIWQEPLACDIFCENGAFSVAQSQR
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCE
ILVKAKALGFRLKLHVDEFEPLGGTPLAVELGAISVDHLVATPPEHIAILANSETVGVSL
EEEEEEECCEEEEEEECCCCCCCCCCEEEEECCEEECCEECCCCCCEEEEECCCEEEEEC
PGTPFGLGKSQFSPARSLIEANGILALATDCNPGTSPCESMPMAIAIACRYLRLTPAEAL
CCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHCCCHHHHH
NAATVNSAFAIRQHERVGSLAVGMQADLALLNLPDERHIGYKFGTNPVAIVIKTGRVVRR
CHHHCCHHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCEEECCCCEEEEEECCCEEEC
NQLHADR
CCCCCCC
>Mature Secondary Structure 
PHADQLITNIGRLVTGPQAPLRGQQLAQLTAIDQAVVAVQAGNIVALGSQAELSAWTAD
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEEECCCEEEECCCCCCEEECCC
QTIDAGGYLAIPGFVDPHTHACYAGDRAHEFELRIKGASYSELMAAGGGIMSTVHATRAA
CEECCCCEEEECCCCCCCCCEEECCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHH
SKAELVAQTRPRLDQLLAHGTTTVEIKSGYGLDTATELTMLEAIAELAQTHPIGIVPTFM
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHH
GAHAIPAEYRDNPEAFVDLVVDEMLPAVAAWWQQQTIWQEPLACDIFCENGAFSVAQSQR
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCE
ILVKAKALGFRLKLHVDEFEPLGGTPLAVELGAISVDHLVATPPEHIAILANSETVGVSL
EEEEEEECCEEEEEEECCCCCCCCCCEEEEECCEEECCEECCCCCCEEEEECCCEEEEEC
PGTPFGLGKSQFSPARSLIEANGILALATDCNPGTSPCESMPMAIAIACRYLRLTPAEAL
CCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHCCCHHHHH
NAATVNSAFAIRQHERVGSLAVGMQADLALLNLPDERHIGYKFGTNPVAIVIKTGRVVRR
CHHHCCHHHHHHHHHHCCCEEECCCCCEEEEECCCCCCCCEEECCCCEEEEEECCCEEEC
NQLHADR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA