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The map label for this gene is pleC [H]

Identifier: 159897123

GI number: 159897123

Start: 684201

End: 686843

Strand: Reverse

Name: pleC [H]

Synonym: Haur_0594

Alternate gene names: 159897123

Gene position: 686843-684201 (Counterclockwise)

Preceding gene: 159897136

Following gene: 159897122

Centisome position: 10.82

GC content: 51.12

Gene sequence:

>2643_bases
ATGACATCACAACCACGAAATGTTCGGTTTGGGGTTCAAGCGCGGGTTTTGTTGCTGGCATTAGGGGTTTCGCTGCCAGC
CTTGATTATTGTGGGCTGGTTGAGCTTGAATGGGATTTCCCAAGCCCGCTTGGCCGCCGTCAAACAAAGCGAAAACACCC
TCTTAATTCAAGCTGAAAACATGCTGATGAGTCGCGCAATCGACAAAGCTGAGCTATATGATCAGGCTTTGTTGAGTGTG
CAGCGCCAAGTCCAAACCATGGTTAATATCACCCAACAGGCCTTCAGCCGCCCACTTGATCGGCTGGCCGACACTCGCCC
CGACCCCTTTTGGCTGGCAGGCAGTGGCCCAACCCTGATTCCCCCTGATCAACTGCGGCTGACCGTGGCTCGTGCTCGCC
AAATTACTGGCGCACTCCAAAGCAACGTCGATCTGAATCCGCTGATTTCTTTGGGCTATTTGGCCACCAAAGAAGGTGTG
ATGGTGCTCGATGATGTGCGGGTCGTTAGCGTATTGCCCGATGGTTTTGATGCCCGTAAACGTCCTTGGTATCAAGCCGC
CGAAAAAGCTACTGGCCCAACTTGGGTCGGAACCTATGTCGATGCCGTCACCAACCAGCTCAATATCACGGTCTCGGCTC
CGGTCAAAGTCAACAATCAGTTGATTGGCGTGATTGGCATGGATTTGCTGCTGACCACGATTCAATCGGATGTGTTGCGG
ATCGATGCAGGCAGTTCGGGCTATGCTTTTGTGATGGATCACGATGGCAATATTTTGATTCGGCCTGAGCTTGAGGCTGG
CAATACCCGTTGGGACGAAACCTTTAAGAAACAGAATTTATTTGAGAGCAACGACCCAAATTTTGTCTCATTACGCGAAA
ATATTCGCAATGATATGGCTGGCGTGACCCGCCTGCAACTCGATGGTGGCGACCGCTATCTGGCCTATTCGCCGATGCGC
ACGGTTGGCTGGGTCGTGGCCTTGGTGCTGCCAATCGACGATGTGATTAGCCCAGCCCGCGATGCGAGTTTGGCAATCGA
ACGCGAGCAAGAGCAGCTACGTCGCAATTTCTTGGCAGTTTTGTTGATCACCTCAGGCTTAATTATTATTTTGGCCACAG
GCTTGGCGCGAACGATCATTCGACCATTGCGCGACCTTGAAGTTGGCGCACAACGAATCGCCTCAGGCCAGCTTGATCAA
GAGTTGGTCGTCCATGGCAATGATGAAATTGGCCGCTTGAGCCTTTCGTTCAATCAGATGACTACAGCGTTACGCGAAAA
AGTCGATGCCTTAGAAGTTAATGCCCAACAGATGGCCGCGATCAATGAAACCAGCAATGAACTCAAACGCTTGCGTTCAT
TAAATACCGTGCTTGATCATATTCCGCAATTATTATGTCAACGCTTAGGGTTTGATCGGGCGGTGCTGTATCTGCTGCGT
GATGAGGTGATCGAGGTAGTTTCGGCCTCATTTGGACCCAACAACTACGAGCTTGAATACGATTTTATGCGGGCAGCGCT
GTCCGAGCCAATTACAATCGATAGCGATACGATTGAAGCCAGCGTAATCAAATCGCGCCAAGCGGTGATCGTCGATAATC
CTTGGGAACATCCGCAGGTAATTCAAGCCAAGCAGTTTATTTCGGGCGGCGATTCGTATGTACAAGCGCCAATTTTGGGC
CGCGAAAAAGTATTGGGCTTGATTTCTGCCGATTACTATGAGCAAGGGCGTTTGGTTACGGTGCAAGATGCAGCGTTACT
GCTCAACTTTGCTGATATGGTCGGCTTGACAATTGAAAACGCCTTCTCATTCCAAAACTTGGAAGATTTGGTGGCCCAAC
GCACTGGCGAGTTGCGCGAAGCTCTCGACCGTGCTCAAGCCGCTGATCGCCTGAAATCGCAGTTTTTGGCCAGCATTTCA
CACGAATTACGCACGCCACTGAACGCAATCATTGGCTTCTCAACCGTGTTGCTCGATGAACTTTCGCCCTTGTTGGTTGA
AGAACAGCGCGAAGACCTTGAAACCATCAACAAAAATGGCCGCTACTTGCTCGATCTGATCAACGATATTTTGGATATGG
CGCGGATCGAAGCTGGCAAATTTGCCCTGCATCGTGAGGCAACGGCAGTGCTGCCAGTCGTGCAATCGGCAGTCGATATT
ATGCATGGTCTGAATTCCAAGCCAGTTACCATGCGCATCGATATTGCGCCCGATTTGCCACGAATGGATGTTGATCCAAC
CCGTTTGCGCCAAATTGTGATTAACCTGATTTCAAATGCGGTAAAATTTACCGACCGTGGCCAAATTGTGGTGCGGGCAA
TTCGGCGGGTAGTCCAAGAAGCTACGCCAATTGGCTCACACTATTTATTGCCCGGCGATTGGATTGTAATCAGCGTCCAA
GATACGGGGATCGGCATGGATGCCGAAGCCTTGGGCAAGCTGTTCCAAGAGTTTCAGCAAGTGCATGCTGGGGCACGCGG
CATTTTGGGGTCGGGCTTGGGGCTTTCGATTACCCGCAGGTTGGTCGATTTGCACGATGGTGATTTATGGGTCGATAGCA
AAGTTGGGGTTGGTAGCACCTTCTCATTTGCGATCGCCACCGCCAGCATCCCAGCGCCGATTGAACAACAATCACCTAGT
TAG

Upstream 100 bases:

>100_bases
TTCATCCGATCCCCAATCAACTATTTTATGCTACACTAGGGGACATTAAACCTACCTACAGATCTGACTCAACTTCCAGC
AATACACGGGGCGTTGGCCT

Downstream 100 bases:

>100_bases
AAGGAAATAACCGTCATGGCAGGTTCGACTCGGGTTCTGTACATTGAGGATAATCACGATAATCAACGTTTAGTACGACG
CGTTCTCGCAACTCGTGGCT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 880; Mature: 879

Protein sequence:

>880_residues
MTSQPRNVRFGVQARVLLLALGVSLPALIIVGWLSLNGISQARLAAVKQSENTLLIQAENMLMSRAIDKAELYDQALLSV
QRQVQTMVNITQQAFSRPLDRLADTRPDPFWLAGSGPTLIPPDQLRLTVARARQITGALQSNVDLNPLISLGYLATKEGV
MVLDDVRVVSVLPDGFDARKRPWYQAAEKATGPTWVGTYVDAVTNQLNITVSAPVKVNNQLIGVIGMDLLLTTIQSDVLR
IDAGSSGYAFVMDHDGNILIRPELEAGNTRWDETFKKQNLFESNDPNFVSLRENIRNDMAGVTRLQLDGGDRYLAYSPMR
TVGWVVALVLPIDDVISPARDASLAIEREQEQLRRNFLAVLLITSGLIIILATGLARTIIRPLRDLEVGAQRIASGQLDQ
ELVVHGNDEIGRLSLSFNQMTTALREKVDALEVNAQQMAAINETSNELKRLRSLNTVLDHIPQLLCQRLGFDRAVLYLLR
DEVIEVVSASFGPNNYELEYDFMRAALSEPITIDSDTIEASVIKSRQAVIVDNPWEHPQVIQAKQFISGGDSYVQAPILG
REKVLGLISADYYEQGRLVTVQDAALLLNFADMVGLTIENAFSFQNLEDLVAQRTGELREALDRAQAADRLKSQFLASIS
HELRTPLNAIIGFSTVLLDELSPLLVEEQREDLETINKNGRYLLDLINDILDMARIEAGKFALHREATAVLPVVQSAVDI
MHGLNSKPVTMRIDIAPDLPRMDVDPTRLRQIVINLISNAVKFTDRGQIVVRAIRRVVQEATPIGSHYLLPGDWIVISVQ
DTGIGMDAEALGKLFQEFQQVHAGARGILGSGLGLSITRRLVDLHDGDLWVDSKVGVGSTFSFAIATASIPAPIEQQSPS

Sequences:

>Translated_880_residues
MTSQPRNVRFGVQARVLLLALGVSLPALIIVGWLSLNGISQARLAAVKQSENTLLIQAENMLMSRAIDKAELYDQALLSV
QRQVQTMVNITQQAFSRPLDRLADTRPDPFWLAGSGPTLIPPDQLRLTVARARQITGALQSNVDLNPLISLGYLATKEGV
MVLDDVRVVSVLPDGFDARKRPWYQAAEKATGPTWVGTYVDAVTNQLNITVSAPVKVNNQLIGVIGMDLLLTTIQSDVLR
IDAGSSGYAFVMDHDGNILIRPELEAGNTRWDETFKKQNLFESNDPNFVSLRENIRNDMAGVTRLQLDGGDRYLAYSPMR
TVGWVVALVLPIDDVISPARDASLAIEREQEQLRRNFLAVLLITSGLIIILATGLARTIIRPLRDLEVGAQRIASGQLDQ
ELVVHGNDEIGRLSLSFNQMTTALREKVDALEVNAQQMAAINETSNELKRLRSLNTVLDHIPQLLCQRLGFDRAVLYLLR
DEVIEVVSASFGPNNYELEYDFMRAALSEPITIDSDTIEASVIKSRQAVIVDNPWEHPQVIQAKQFISGGDSYVQAPILG
REKVLGLISADYYEQGRLVTVQDAALLLNFADMVGLTIENAFSFQNLEDLVAQRTGELREALDRAQAADRLKSQFLASIS
HELRTPLNAIIGFSTVLLDELSPLLVEEQREDLETINKNGRYLLDLINDILDMARIEAGKFALHREATAVLPVVQSAVDI
MHGLNSKPVTMRIDIAPDLPRMDVDPTRLRQIVINLISNAVKFTDRGQIVVRAIRRVVQEATPIGSHYLLPGDWIVISVQ
DTGIGMDAEALGKLFQEFQQVHAGARGILGSGLGLSITRRLVDLHDGDLWVDSKVGVGSTFSFAIATASIPAPIEQQSPS
>Mature_879_residues
TSQPRNVRFGVQARVLLLALGVSLPALIIVGWLSLNGISQARLAAVKQSENTLLIQAENMLMSRAIDKAELYDQALLSVQ
RQVQTMVNITQQAFSRPLDRLADTRPDPFWLAGSGPTLIPPDQLRLTVARARQITGALQSNVDLNPLISLGYLATKEGVM
VLDDVRVVSVLPDGFDARKRPWYQAAEKATGPTWVGTYVDAVTNQLNITVSAPVKVNNQLIGVIGMDLLLTTIQSDVLRI
DAGSSGYAFVMDHDGNILIRPELEAGNTRWDETFKKQNLFESNDPNFVSLRENIRNDMAGVTRLQLDGGDRYLAYSPMRT
VGWVVALVLPIDDVISPARDASLAIEREQEQLRRNFLAVLLITSGLIIILATGLARTIIRPLRDLEVGAQRIASGQLDQE
LVVHGNDEIGRLSLSFNQMTTALREKVDALEVNAQQMAAINETSNELKRLRSLNTVLDHIPQLLCQRLGFDRAVLYLLRD
EVIEVVSASFGPNNYELEYDFMRAALSEPITIDSDTIEASVIKSRQAVIVDNPWEHPQVIQAKQFISGGDSYVQAPILGR
EKVLGLISADYYEQGRLVTVQDAALLLNFADMVGLTIENAFSFQNLEDLVAQRTGELREALDRAQAADRLKSQFLASISH
ELRTPLNAIIGFSTVLLDELSPLLVEEQREDLETINKNGRYLLDLINDILDMARIEAGKFALHREATAVLPVVQSAVDIM
HGLNSKPVTMRIDIAPDLPRMDVDPTRLRQIVINLISNAVKFTDRGQIVVRAIRRVVQEATPIGSHYLLPGDWIVISVQD
TGIGMDAEALGKLFQEFQQVHAGARGILGSGLGLSITRRLVDLHDGDLWVDSKVGVGSTFSFAIATASIPAPIEQQSPS

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=287, Percent_Identity=37.6306620209059, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1789149, Length=283, Percent_Identity=36.3957597173145, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI48994928, Length=262, Percent_Identity=36.2595419847328, Blast_Score=147, Evalue=4e-36,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=37.2093023255814, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1788713, Length=283, Percent_Identity=31.4487632508834, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1786912, Length=401, Percent_Identity=26.4339152119701, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=29.7872340425532, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=278, Percent_Identity=28.4172661870504, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=25.8823529411765, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=269, Percent_Identity=24.5353159851301, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 96968; Mature: 96836

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS00041 HTH_ARAC_FAMILY_1 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQPRNVRFGVQARVLLLALGVSLPALIIVGWLSLNGISQARLAAVKQSENTLLIQAEN
CCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEHH
MLMSRAIDKAELYDQALLSVQRQVQTMVNITQQAFSRPLDRLADTRPDPFWLAGSGPTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
PPDQLRLTVARARQITGALQSNVDLNPLISLGYLATKEGVMVLDDVRVVSVLPDGFDARK
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCEEEEECCCCCCCCC
RPWYQAAEKATGPTWVGTYVDAVTNQLNITVSAPVKVNNQLIGVIGMDLLLTTIQSDVLR
CCHHHHHHHCCCCCHHHHHHHHHCCEEEEEEECCEEECCCEEHHHHHHHHHHHHHHHHEE
IDAGSSGYAFVMDHDGNILIRPELEAGNTRWDETFKKQNLFESNDPNFVSLRENIRNDMA
EECCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHC
GVTRLQLDGGDRYLAYSPMRTVGWVVALVLPIDDVISPARDASLAIEREQEQLRRNFLAV
CCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LLITSGLIIILATGLARTIIRPLRDLEVGAQRIASGQLDQELVVHGNDEIGRLSLSFNQM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEHHHH
TTALREKVDALEVNAQQMAAINETSNELKRLRSLNTVLDHIPQLLCQRLGFDRAVLYLLR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DEVIEVVSASFGPNNYELEYDFMRAALSEPITIDSDTIEASVIKSRQAVIVDNPWEHPQV
HHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEECCCCHHHHHHCCCCEEEECCCCCCCHH
IQAKQFISGGDSYVQAPILGREKVLGLISADYYEQGRLVTVQDAALLLNFADMVGLTIEN
HHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
AFSFQNLEDLVAQRTGELREALDRAQAADRLKSQFLASISHELRTPLNAIIGFSTVLLDE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSPLLVEEQREDLETINKNGRYLLDLINDILDMARIEAGKFALHREATAVLPVVQSAVDI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MHGLNSKPVTMRIDIAPDLPRMDVDPTRLRQIVINLISNAVKFTDRGQIVVRAIRRVVQE
HHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ATPIGSHYLLPGDWIVISVQDTGIGMDAEALGKLFQEFQQVHAGARGILGSGLGLSITRR
CCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LVDLHDGDLWVDSKVGVGSTFSFAIATASIPAPIEQQSPS
HHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TSQPRNVRFGVQARVLLLALGVSLPALIIVGWLSLNGISQARLAAVKQSENTLLIQAEN
CCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEHH
MLMSRAIDKAELYDQALLSVQRQVQTMVNITQQAFSRPLDRLADTRPDPFWLAGSGPTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
PPDQLRLTVARARQITGALQSNVDLNPLISLGYLATKEGVMVLDDVRVVSVLPDGFDARK
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCEEEEECCCCCCCCC
RPWYQAAEKATGPTWVGTYVDAVTNQLNITVSAPVKVNNQLIGVIGMDLLLTTIQSDVLR
CCHHHHHHHCCCCCHHHHHHHHHCCEEEEEEECCEEECCCEEHHHHHHHHHHHHHHHHEE
IDAGSSGYAFVMDHDGNILIRPELEAGNTRWDETFKKQNLFESNDPNFVSLRENIRNDMA
EECCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHC
GVTRLQLDGGDRYLAYSPMRTVGWVVALVLPIDDVISPARDASLAIEREQEQLRRNFLAV
CCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LLITSGLIIILATGLARTIIRPLRDLEVGAQRIASGQLDQELVVHGNDEIGRLSLSFNQM
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEHHHH
TTALREKVDALEVNAQQMAAINETSNELKRLRSLNTVLDHIPQLLCQRLGFDRAVLYLLR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DEVIEVVSASFGPNNYELEYDFMRAALSEPITIDSDTIEASVIKSRQAVIVDNPWEHPQV
HHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCEECCCCHHHHHHCCCCEEEECCCCCCCHH
IQAKQFISGGDSYVQAPILGREKVLGLISADYYEQGRLVTVQDAALLLNFADMVGLTIEN
HHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
AFSFQNLEDLVAQRTGELREALDRAQAADRLKSQFLASISHELRTPLNAIIGFSTVLLDE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSPLLVEEQREDLETINKNGRYLLDLINDILDMARIEAGKFALHREATAVLPVVQSAVDI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MHGLNSKPVTMRIDIAPDLPRMDVDPTRLRQIVINLISNAVKFTDRGQIVVRAIRRVVQE
HHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ATPIGSHYLLPGDWIVISVQDTGIGMDAEALGKLFQEFQQVHAGARGILGSGLGLSITRR
CCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LVDLHDGDLWVDSKVGVGSTFSFAIATASIPAPIEQQSPS
HHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]