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The map label for this gene is fabH [H]

Identifier: 159896904

GI number: 159896904

Start: 445114

End: 446100

Strand: Reverse

Name: fabH [H]

Synonym: Haur_0372

Alternate gene names: 159896904

Gene position: 446100-445114 (Counterclockwise)

Preceding gene: 159896905

Following gene: 159896903

Centisome position: 7.03

GC content: 54.51

Gene sequence:

>987_bases
ATGCAGTTTCCTCTGCGCATCGCCGGAATCGGCGCGTACTTACCAGCCACCATTGTTACCACCAGCGAGCTAGCCGAGCG
CTTTGGCGTTGATCCAGGCTTAATTGAGCGAATCACGGGCATTCGTGAGCGCCGTTACGCTGGAGCTGAAACTGCCTTGA
CCATGGCCACCCAAGCCGCCCAGCAAGCACTAGCCAACGCCAATTATGCGCTTGATAGCATCGATTTAATCGTGGTGGCT
TCGGCTGGAATGCATCAAGCCATCCCATGCACGGCGGCCTTATTGCAAAACGCCTTGCAAGCACCAGTGGGCCGTAGCGC
CTGCTTCGATTTGAATGCAACCTGTATGAGTTTTATGCTGGCATTGCAATTGTTAGCGCCATTAATTAATAGTGGCGTGT
ATCAACGAGTGCTGTTAGTCAGCAGCGAACGGGCTTCAGTTTCGCTCAATCCACATGAATGGGAATCGACAGCGCTATTT
GGCGATGCAGCAGCGGCAGTCGTGTTGGAGCGCGGCGATGGCAGCAGCAGCCTGCAACATAGCCAATTTGCCACCTGGAG
CAATGGCAGCGATTTGATTCAGGTGCGCGGCGGCGGCACGGCCCAGCATCCCAACGCGGCAGATACCACGCCCGACATGA
ATTGGTTTATGATGCAGGGGCCGTTGGCGTTTCGCTTTGTCTTGCGCGAAATGCAGCAGTTTGTTGAACGATTTTTGGCT
GAGCTAGGTTGGCAAAATAGTGAAATTGATGCAGTTATTCCCCATCAAGCCAACCGCCATGCGATCGAGCAAGTGCAAGC
ACGCTTGGGCTTTCAGCCCGATCAAGTAATTAGCAATCTCGCTACCCGAGGCAATTGCGTTTCGGTATCCGTGCCCTTAG
CCTTGGCTGAAGCGGTTGCGGCTGGCCGAATTCAGCGTGGCAACCGCTTGGTGCTGCTTGGCTCTGGCGCTGGAATTACC
TTGGGTGCTGTGGCGTTGATTTACTAA

Upstream 100 bases:

>100_bases
GCGGCGCAACAACTTGCGACCCAATTAGCCCAAGAGCAAGGCGTAACCAAGGCCATAGCTTGGTTAAAACAACGATTTTG
AAATTACACGAGGTAGTGTT

Downstream 100 bases:

>100_bases
CTAGGAAATCGCGATGGTTGGGTTGATTACTGGGGCAGGCACGGGCATTGGTCAGGCCATGGCCTTGGCCTTGGCCAAAC
GTGGCGCAACCATTATTTTA

Product: beta-ketoacyl-acyl-carrier-protein synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MQFPLRIAGIGAYLPATIVTTSELAERFGVDPGLIERITGIRERRYAGAETALTMATQAAQQALANANYALDSIDLIVVA
SAGMHQAIPCTAALLQNALQAPVGRSACFDLNATCMSFMLALQLLAPLINSGVYQRVLLVSSERASVSLNPHEWESTALF
GDAAAAVVLERGDGSSSLQHSQFATWSNGSDLIQVRGGGTAQHPNAADTTPDMNWFMMQGPLAFRFVLREMQQFVERFLA
ELGWQNSEIDAVIPHQANRHAIEQVQARLGFQPDQVISNLATRGNCVSVSVPLALAEAVAAGRIQRGNRLVLLGSGAGIT
LGAVALIY

Sequences:

>Translated_328_residues
MQFPLRIAGIGAYLPATIVTTSELAERFGVDPGLIERITGIRERRYAGAETALTMATQAAQQALANANYALDSIDLIVVA
SAGMHQAIPCTAALLQNALQAPVGRSACFDLNATCMSFMLALQLLAPLINSGVYQRVLLVSSERASVSLNPHEWESTALF
GDAAAAVVLERGDGSSSLQHSQFATWSNGSDLIQVRGGGTAQHPNAADTTPDMNWFMMQGPLAFRFVLREMQQFVERFLA
ELGWQNSEIDAVIPHQANRHAIEQVQARLGFQPDQVISNLATRGNCVSVSVPLALAEAVAAGRIQRGNRLVLLGSGAGIT
LGAVALIY
>Mature_328_residues
MQFPLRIAGIGAYLPATIVTTSELAERFGVDPGLIERITGIRERRYAGAETALTMATQAAQQALANANYALDSIDLIVVA
SAGMHQAIPCTAALLQNALQAPVGRSACFDLNATCMSFMLALQLLAPLINSGVYQRVLLVSSERASVSLNPHEWESTALF
GDAAAAVVLERGDGSSSLQHSQFATWSNGSDLIQVRGGGTAQHPNAADTTPDMNWFMMQGPLAFRFVLREMQQFVERFLA
ELGWQNSEIDAVIPHQANRHAIEQVQARLGFQPDQVISNLATRGNCVSVSVPLALAEAVAAGRIQRGNRLVLLGSGAGIT
LGAVALIY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=32.6086956521739, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34969; Mature: 34969

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFPLRIAGIGAYLPATIVTTSELAERFGVDPGLIERITGIRERRYAGAETALTMATQAA
CCCCEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QQALANANYALDSIDLIVVASAGMHQAIPCTAALLQNALQAPVGRSACFDLNATCMSFML
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHH
ALQLLAPLINSGVYQRVLLVSSERASVSLNPHEWESTALFGDAAAAVVLERGDGSSSLQH
HHHHHHHHHCCHHHHHHHEEECCCCEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCCH
SQFATWSNGSDLIQVRGGGTAQHPNAADTTPDMNWFMMQGPLAFRFVLREMQQFVERFLA
HHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
ELGWQNSEIDAVIPHQANRHAIEQVQARLGFQPDQVISNLATRGNCVSVSVPLALAEAVA
HHCCCCCCCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHH
AGRIQRGNRLVLLGSGAGITLGAVALIY
HHHHCCCCEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MQFPLRIAGIGAYLPATIVTTSELAERFGVDPGLIERITGIRERRYAGAETALTMATQAA
CCCCEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QQALANANYALDSIDLIVVASAGMHQAIPCTAALLQNALQAPVGRSACFDLNATCMSFML
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHH
ALQLLAPLINSGVYQRVLLVSSERASVSLNPHEWESTALFGDAAAAVVLERGDGSSSLQH
HHHHHHHHHCCHHHHHHHEEECCCCEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCCH
SQFATWSNGSDLIQVRGGGTAQHPNAADTTPDMNWFMMQGPLAFRFVLREMQQFVERFLA
HHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
ELGWQNSEIDAVIPHQANRHAIEQVQARLGFQPDQVISNLATRGNCVSVSVPLALAEAVA
HHCCCCCCCCEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHH
AGRIQRGNRLVLLGSGAGITLGAVALIY
HHHHCCCCEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]