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The map label for this gene is acr1 [H]

Identifier: 159896903

GI number: 159896903

Start: 444342

End: 445100

Strand: Reverse

Name: acr1 [H]

Synonym: Haur_0371

Alternate gene names: 159896903

Gene position: 445100-444342 (Counterclockwise)

Preceding gene: 159896904

Following gene: 159896902

Centisome position: 7.01

GC content: 54.41

Gene sequence:

>759_bases
ATGGTTGGGTTGATTACTGGGGCAGGCACGGGCATTGGTCAGGCCATGGCCTTGGCCTTGGCCAAACGTGGCGCAACCAT
TATTTTAGTTGGTCGCCGCCGCGAACCACTGCTGCAAACGGCCAGCTTGGTTACCCAACTTGGTGGTCAAGCTTGGCCGA
TCGTCTGTGATTTGAGCGATCATGAAGCGGTTGCCGCCCTCGCTGCTCAAATCACCCAACGTTATGTTCAGCTCGATCTA
TTGATTCACAATGCGGCAGTGCTAGCGGGCGGTGCGTTTGATCAGCTACCAGAATCAGCCATCCTTGCAACCCTCAATGC
CAATTTGCTGCACCCAATTTGGCTCACCCGACAACTACTGCCTAAAACAGTATTGATTGTTGGCAGCACGGTTAGCCGCG
TGGCCATGCCTGGAGCCAGCTTGTATAGCCTGAGCAAAGCTGCGCTTGAGGCTTGGGGCTTGGCACTGACAGCCGAAACC
ACGATCAAGATTGTGCGGGTCTACCCCCCAGCCACCAAAACCGCCATGACCACAGCCATGGCCCAACAAACTGGCCAACG
CTTCCCACTCGCTGAGGCCAATAAAGTTGGCGAACAGATTATCCAGCGCTATTTGGCGGGCGAAACCGAAATTGTGCTGA
GTGCCAGTGATCGCTGGCTATTTCGCTTGCAACGCTATGCCCCAAAACGGTTGCAAGCCTTGCTCAAACGCTATCATCAA
CAGCTGATCAAGCTCTGGGGTGGCTCGACAATTATTTGA

Upstream 100 bases:

>100_bases
GCTGGCCGAATTCAGCGTGGCAACCGCTTGGTGCTGCTTGGCTCTGGCGCTGGAATTACCTTGGGTGCTGTGGCGTTGAT
TTACTAACTAGGAAATCGCG

Downstream 100 bases:

>100_bases
CAAACAGCGATCAGCCGTCTACAATTGCCGCTTTGTTGATACTTGATATCAATAATTAGATAGAAAGGTCTAGCAATGCG
GCGTTTAACTCAGCTTTTAG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MVGLITGAGTGIGQAMALALAKRGATIILVGRRREPLLQTASLVTQLGGQAWPIVCDLSDHEAVAALAAQITQRYVQLDL
LIHNAAVLAGGAFDQLPESAILATLNANLLHPIWLTRQLLPKTVLIVGSTVSRVAMPGASLYSLSKAALEAWGLALTAET
TIKIVRVYPPATKTAMTTAMAQQTGQRFPLAEANKVGEQIIQRYLAGETEIVLSASDRWLFRLQRYAPKRLQALLKRYHQ
QLIKLWGGSTII

Sequences:

>Translated_252_residues
MVGLITGAGTGIGQAMALALAKRGATIILVGRRREPLLQTASLVTQLGGQAWPIVCDLSDHEAVAALAAQITQRYVQLDL
LIHNAAVLAGGAFDQLPESAILATLNANLLHPIWLTRQLLPKTVLIVGSTVSRVAMPGASLYSLSKAALEAWGLALTAET
TIKIVRVYPPATKTAMTTAMAQQTGQRFPLAEANKVGEQIIQRYLAGETEIVLSASDRWLFRLQRYAPKRLQALLKRYHQ
QLIKLWGGSTII
>Mature_252_residues
MVGLITGAGTGIGQAMALALAKRGATIILVGRRREPLLQTASLVTQLGGQAWPIVCDLSDHEAVAALAAQITQRYVQLDL
LIHNAAVLAGGAFDQLPESAILATLNANLLHPIWLTRQLLPKTVLIVGSTVSRVAMPGASLYSLSKAALEAWGLALTAET
TIKIVRVYPPATKTAMTTAMAQQTGQRFPLAEANKVGEQIIQRYLAGETEIVLSASDRWLFRLQRYAPKRLQALLKRYHQ
QLIKLWGGSTII

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI210032110, Length=247, Percent_Identity=25.9109311740891, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI310128830, Length=222, Percent_Identity=25.2252252252252, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI310115468, Length=222, Percent_Identity=25.2252252252252, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI40807363, Length=249, Percent_Identity=23.2931726907631, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI142976729, Length=247, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI31543615, Length=199, Percent_Identity=26.6331658291457, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4503817, Length=186, Percent_Identity=26.3440860215054, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=220, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787526, Length=210, Percent_Identity=30, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=248, Percent_Identity=22.9838709677419, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=216, Percent_Identity=26.8518518518519, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=182, Percent_Identity=27.4725274725275, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=214, Percent_Identity=22.8971962616822, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=214, Percent_Identity=22.8971962616822, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=263, Percent_Identity=23.574144486692, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=183, Percent_Identity=28.4153005464481, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI23397609, Length=170, Percent_Identity=33.5294117647059, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640492, Length=202, Percent_Identity=24.7524752475248, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=235, Percent_Identity=25.1063829787234, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=254, Percent_Identity=22.8346456692913, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571526, Length=172, Percent_Identity=30.8139534883721, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=265, Percent_Identity=25.2830188679245, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=29.7979797979798, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24643142, Length=169, Percent_Identity=34.3195266272189, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357041, Length=171, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24581726, Length=244, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27163; Mature: 27163

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLITGAGTGIGQAMALALAKRGATIILVGRRREPLLQTASLVTQLGGQAWPIVCDLSD
CEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCC
HEAVAALAAQITQRYVQLDLLIHNAAVLAGGAFDQLPESAILATLNANLLHPIWLTRQLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHH
PKTVLIVGSTVSRVAMPGASLYSLSKAALEAWGLALTAETTIKIVRVYPPATKTAMTTAM
HHEEEEECCHHHHHHCCCHHHHHHHHHHHHHHCEEEEECCEEEEEEEECCCHHHHHHHHH
AQQTGQRFPLAEANKVGEQIIQRYLAGETEIVLSASDRWLFRLQRYAPKRLQALLKRYHQ
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHH
QLIKLWGGSTII
HHHHHHCCCCCC
>Mature Secondary Structure
MVGLITGAGTGIGQAMALALAKRGATIILVGRRREPLLQTASLVTQLGGQAWPIVCDLSD
CEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCC
HEAVAALAAQITQRYVQLDLLIHNAAVLAGGAFDQLPESAILATLNANLLHPIWLTRQLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHH
PKTVLIVGSTVSRVAMPGASLYSLSKAALEAWGLALTAETTIKIVRVYPPATKTAMTTAM
HHEEEEECCHHHHHHCCCHHHHHHHHHHHHHHCEEEEECCEEEEEEEECCCHHHHHHHHH
AQQTGQRFPLAEANKVGEQIIQRYLAGETEIVLSASDRWLFRLQRYAPKRLQALLKRYHQ
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHH
QLIKLWGGSTII
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA