Click here to switch to the map view.

The map label for this gene is htpG [H]

Identifier: 159896855

GI number: 159896855

Start: 383077

End: 384951

Strand: Direct

Name: htpG [H]

Synonym: Haur_0322

Alternate gene names: 159896855

Gene position: 383077-384951 (Clockwise)

Preceding gene: 159896851

Following gene: 159896856

Centisome position: 6.04

GC content: 51.09

Gene sequence:

>1875_bases
ATGGCTGAGCAACACGATGTTGCCAATGAGCGCGAACAGTTTCAATTCCAGGCTGAAATCCAACAAGTTTTGCATATTCT
GATTCACTCGCTGTATACCCACCGCGAGATTTTTGTGCGCGAATTAATCTCGAATGCTTCCGATGCCTTGAATCGGGTGC
AATTTGAGATGTTGACCAACCAAGATGTGCGCGACCCCGAGCTTGAATTGGCGATCACGTTGGAAGCCGATAAAGATGCG
CGGATCATTCGGATCAGCGATACGGGTATCGGCATGACCCGCGATGATATGATCAAGAATTTGGGCACGGTGGCGCAATC
TGGCGCGAAAGCCTTTTTGCAAAAGTTGGGCGAAGCCAACCCAACCAACAGCAGCGAAATTATTGGTCAATTTGGCGTAG
GCTTCTACTCGGTGTTTATGGCTGCCGATGAAGTGCGGGTCACCTCGCTGTCGTATCAGCCCGATGCAACTGCTTGGCGC
TGGACATCGCGCGGCGAAGCAACCTACACCTTGGAAGCAGCCGAACGCAGCGAACGCGGCACGACGATCGAAATTGTGCT
CAAAGAAGATGCCGAAGAATATGCCGAACGCTGGAAACTTGACCAAATTGTGCGCCAACACTCCAATTTTGTGGCCTTCC
CAATTTATTCGGCTGAGGGCGACGAAAAGAAAGTGCTCAACCAACGCACGGCGCTTTGGCGCAAGCAGCCACGCGAAGTC
ACCCAAGAAGAATATAACGATTTCTATCGCCAAACCACGATGGATTTCAACGAGCCATTGAGCACAATTCACATTAGTAC
CGATGCTCCGGTCGATTTGCACGCAATTTTGTTCTTGCCCGCCAAACGTGAGCAAGGCATGATGCGCCAAATTCCTGATC
CAGGTTTGAAACTTTATTCGCGCAAGGTGCTGATCCAAGAGCGCAACGAAGAATTGTTGCCCAAACATCTGCGCTTTGTC
CAAGGTGTGGTCGATTCGGAAGATTTGCCGTTGAATGTCTCGCGTGAAACCGTGCAAAGCAGCGGCACATTACGCCAAAT
TGCCAAAATTGTGACCAACAAAATTACCAAAGAAATTGAAACCTTGGCCGAAAACGATGCCGAAAAGTTTGCTGACTTCT
GGCGTGAATTTGGGCCATATTTCAAAGAAGGCTTGGTTACCGATCCTGGCACGCGCAGCCAAATTGAGCCACTATTGCGC
TTCCACTCGACCAGCGGCGAGGGCTTGACCAAGCTCAGCGAGTATGTTGAGCGCATGAAGGAAGGCCAAGAAGATATTTA
TTATGTGATTGCCGACAACGTGGAAACTGCCCGCCGTTCGCCACATCTCGATTATTTCAACGAACGCGGCTACGAAGTGC
TGTTGATGCATGAAACGATTGATAGCTTTGTCATCTCCAGTTTGCGCGATTTCCAAGGCAAAAAATTGCGCTCAGTCGAT
GATGCCGATATTGCGGGCGACGATGTTGAGCTAGAAGGCTCGCTCTCAGCAGCAACGCTTGGCCAACTGGGCGACCGCAT
CAAAGAATTATTGGGCGAGCAAATCAGCGAAGTGCGTGGCTCGAAGTTGCTGCGCAGCAACCCTGTGCGTTTGGCCGCGC
CTAGCGACGATTTTGGCCGCGATATGGATCGCATTCGGCGTATGATGGGTCAAGAATATAGCGTTCCTAGCCGAATTCTA
GAACTCAACCCACGCCACGCGATTGTGCACAACTTGGCCGCCTTGCTCGATGAGCCAGATCAAGCCGAATTGTTCGAGGT
TGCGGTGCAACAATTGTATGGCACGGCTTTGTTGGGCGAAGGCTTACACCCCAACCCCAGCGAGTTGATCAGCGGTGTCC
ATGCCTTGATCGCTGCCGCTACCAAAAAACAATAA

Upstream 100 bases:

>100_bases
ACAACGCTAACGTAGCAAGCTTCTCGTGGTAGGCATGGCTATGCTACAATCGGCCTAGCGGTTTAAGCCCAATTAAGCGT
TTTATAAGGAGTAGCGACCT

Downstream 100 bases:

>100_bases
GTCTGAATGCCCTCACCCCAACCCCTCTCCCACTGCGGTGGGAGAGGGGCTTTTTGTTAAATCCCCAACTTGCGACTGAT
TACGCCCCAAATCATTGTGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MAEQHDVANEREQFQFQAEIQQVLHILIHSLYTHREIFVRELISNASDALNRVQFEMLTNQDVRDPELELAITLEADKDA
RIIRISDTGIGMTRDDMIKNLGTVAQSGAKAFLQKLGEANPTNSSEIIGQFGVGFYSVFMAADEVRVTSLSYQPDATAWR
WTSRGEATYTLEAAERSERGTTIEIVLKEDAEEYAERWKLDQIVRQHSNFVAFPIYSAEGDEKKVLNQRTALWRKQPREV
TQEEYNDFYRQTTMDFNEPLSTIHISTDAPVDLHAILFLPAKREQGMMRQIPDPGLKLYSRKVLIQERNEELLPKHLRFV
QGVVDSEDLPLNVSRETVQSSGTLRQIAKIVTNKITKEIETLAENDAEKFADFWREFGPYFKEGLVTDPGTRSQIEPLLR
FHSTSGEGLTKLSEYVERMKEGQEDIYYVIADNVETARRSPHLDYFNERGYEVLLMHETIDSFVISSLRDFQGKKLRSVD
DADIAGDDVELEGSLSAATLGQLGDRIKELLGEQISEVRGSKLLRSNPVRLAAPSDDFGRDMDRIRRMMGQEYSVPSRIL
ELNPRHAIVHNLAALLDEPDQAELFEVAVQQLYGTALLGEGLHPNPSELISGVHALIAAATKKQ

Sequences:

>Translated_624_residues
MAEQHDVANEREQFQFQAEIQQVLHILIHSLYTHREIFVRELISNASDALNRVQFEMLTNQDVRDPELELAITLEADKDA
RIIRISDTGIGMTRDDMIKNLGTVAQSGAKAFLQKLGEANPTNSSEIIGQFGVGFYSVFMAADEVRVTSLSYQPDATAWR
WTSRGEATYTLEAAERSERGTTIEIVLKEDAEEYAERWKLDQIVRQHSNFVAFPIYSAEGDEKKVLNQRTALWRKQPREV
TQEEYNDFYRQTTMDFNEPLSTIHISTDAPVDLHAILFLPAKREQGMMRQIPDPGLKLYSRKVLIQERNEELLPKHLRFV
QGVVDSEDLPLNVSRETVQSSGTLRQIAKIVTNKITKEIETLAENDAEKFADFWREFGPYFKEGLVTDPGTRSQIEPLLR
FHSTSGEGLTKLSEYVERMKEGQEDIYYVIADNVETARRSPHLDYFNERGYEVLLMHETIDSFVISSLRDFQGKKLRSVD
DADIAGDDVELEGSLSAATLGQLGDRIKELLGEQISEVRGSKLLRSNPVRLAAPSDDFGRDMDRIRRMMGQEYSVPSRIL
ELNPRHAIVHNLAALLDEPDQAELFEVAVQQLYGTALLGEGLHPNPSELISGVHALIAAATKKQ
>Mature_623_residues
AEQHDVANEREQFQFQAEIQQVLHILIHSLYTHREIFVRELISNASDALNRVQFEMLTNQDVRDPELELAITLEADKDAR
IIRISDTGIGMTRDDMIKNLGTVAQSGAKAFLQKLGEANPTNSSEIIGQFGVGFYSVFMAADEVRVTSLSYQPDATAWRW
TSRGEATYTLEAAERSERGTTIEIVLKEDAEEYAERWKLDQIVRQHSNFVAFPIYSAEGDEKKVLNQRTALWRKQPREVT
QEEYNDFYRQTTMDFNEPLSTIHISTDAPVDLHAILFLPAKREQGMMRQIPDPGLKLYSRKVLIQERNEELLPKHLRFVQ
GVVDSEDLPLNVSRETVQSSGTLRQIAKIVTNKITKEIETLAENDAEKFADFWREFGPYFKEGLVTDPGTRSQIEPLLRF
HSTSGEGLTKLSEYVERMKEGQEDIYYVIADNVETARRSPHLDYFNERGYEVLLMHETIDSFVISSLRDFQGKKLRSVDD
ADIAGDDVELEGSLSAATLGQLGDRIKELLGEQISEVRGSKLLRSNPVRLAAPSDDFGRDMDRIRRMMGQEYSVPSRILE
LNPRHAIVHNLAALLDEPDQAELFEVAVQQLYGTALLGEGLHPNPSELISGVHALIAAATKKQ

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=644, Percent_Identity=35.2484472049689, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI4507677, Length=660, Percent_Identity=32.2727272727273, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI20149594, Length=392, Percent_Identity=34.4387755102041, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI154146191, Length=392, Percent_Identity=31.6326530612245, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI153792590, Length=390, Percent_Identity=31.025641025641, Blast_Score=196, Evalue=8e-50,
Organism=Escherichia coli, GI1786679, Length=622, Percent_Identity=37.9421221864952, Blast_Score=439, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI115535205, Length=635, Percent_Identity=36.0629921259843, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17559162, Length=649, Percent_Identity=32.9738058551618, Blast_Score=358, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI17542208, Length=651, Percent_Identity=33.3333333333333, Blast_Score=346, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI115535167, Length=425, Percent_Identity=41.4117647058824, Blast_Score=305, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6325016, Length=405, Percent_Identity=32.8395061728395, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6323840, Length=405, Percent_Identity=32.3456790123457, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24586016, Length=642, Percent_Identity=36.2928348909657, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17647529, Length=664, Percent_Identity=33.2831325301205, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI21357739, Length=670, Percent_Identity=31.4925373134328, Blast_Score=343, Evalue=1e-94,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70800; Mature: 70668

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQHDVANEREQFQFQAEIQQVLHILIHSLYTHREIFVRELISNASDALNRVQFEMLTN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDVRDPELELAITLEADKDARIIRISDTGIGMTRDDMIKNLGTVAQSGAKAFLQKLGEAN
CCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PTNSSEIIGQFGVGFYSVFMAADEVRVTSLSYQPDATAWRWTSRGEATYTLEAAERSERG
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEECCCCCEEEEEECHHHCCCC
TTIEIVLKEDAEEYAERWKLDQIVRQHSNFVAFPIYSAEGDEKKVLNQRTALWRKQPREV
CEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHH
TQEEYNDFYRQTTMDFNEPLSTIHISTDAPVDLHAILFLPAKREQGMMRQIPDPGLKLYS
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEEECHHHCCHHHCCCCCCHHHHH
RKVLIQERNEELLPKHLRFVQGVVDSEDLPLNVSRETVQSSGTLRQIAKIVTNKITKEIE
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
TLAENDAEKFADFWREFGPYFKEGLVTDPGTRSQIEPLLRFHSTSGEGLTKLSEYVERMK
HHHHCCHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EGQEDIYYVIADNVETARRSPHLDYFNERGYEVLLMHETIDSFVISSLRDFQGKKLRSVD
CCCCCEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCC
DADIAGDDVELEGSLSAATLGQLGDRIKELLGEQISEVRGSKLLRSNPVRLAAPSDDFGR
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHH
DMDRIRRMMGQEYSVPSRILELNPRHAIVHNLAALLDEPDQAELFEVAVQQLYGTALLGE
HHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GLHPNPSELISGVHALIAAATKKQ
CCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEQHDVANEREQFQFQAEIQQVLHILIHSLYTHREIFVRELISNASDALNRVQFEMLTN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDVRDPELELAITLEADKDARIIRISDTGIGMTRDDMIKNLGTVAQSGAKAFLQKLGEAN
CCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PTNSSEIIGQFGVGFYSVFMAADEVRVTSLSYQPDATAWRWTSRGEATYTLEAAERSERG
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEECCCCCEEEEEECHHHCCCC
TTIEIVLKEDAEEYAERWKLDQIVRQHSNFVAFPIYSAEGDEKKVLNQRTALWRKQPREV
CEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHH
TQEEYNDFYRQTTMDFNEPLSTIHISTDAPVDLHAILFLPAKREQGMMRQIPDPGLKLYS
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEEEECHHHCCHHHCCCCCCHHHHH
RKVLIQERNEELLPKHLRFVQGVVDSEDLPLNVSRETVQSSGTLRQIAKIVTNKITKEIE
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
TLAENDAEKFADFWREFGPYFKEGLVTDPGTRSQIEPLLRFHSTSGEGLTKLSEYVERMK
HHHHCCHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EGQEDIYYVIADNVETARRSPHLDYFNERGYEVLLMHETIDSFVISSLRDFQGKKLRSVD
CCCCCEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCC
DADIAGDDVELEGSLSAATLGQLGDRIKELLGEQISEVRGSKLLRSNPVRLAAPSDDFGR
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHH
DMDRIRRMMGQEYSVPSRILELNPRHAIVHNLAALLDEPDQAELFEVAVQQLYGTALLGE
HHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GLHPNPSELISGVHALIAAATKKQ
CCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA