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The map label for this gene is 159896687

Identifier: 159896687

GI number: 159896687

Start: 184887

End: 185924

Strand: Direct

Name: 159896687

Synonym: Haur_0154

Alternate gene names: NA

Gene position: 184887-185924 (Clockwise)

Preceding gene: 159896684

Following gene: 159896688

Centisome position: 2.91

GC content: 53.28

Gene sequence:

>1038_bases
ATGAGCCTCGCTCTCATTTCACACGATCATTATCTCGACCACGATCAGCCTGAGCACCCCGAAAATGCCAATCGGCTACG
GGCGATTCATGCCATGCTGGCAGCTGATTATGAATTGCAACAGCACTTAACCCCGCTTGCACCACGCCATGCAACTGCTG
CTGAAATCGAGGCGGTGCATGTGCCAAGCCATTTGCCAACCCTACAACGGATGGCCCAATTTGGCGATTGGGCTGATGCT
GAAACCTATATTTTGCCAGATTCGGTCGAGATTGCCCAACTTGCTGCTGGCGGCGCGATTGTCGCGACTGATGCAGTGCT
CAGTGGTCGGCATGCCAATAGTTTTGCTTTGGTTCGCCCACCAGGCCATCATGCGACCGCCGACCAAGCTATGGGATTTT
GCTTGTTCAATAATGCGGCGATTGCGGCGGCCTTTGCTCAACGTGAATATGGCCTCAAACGAGTGGCAATTTTGGATTGG
GACGTGCATCATGGCAACGGAACCCAAGATATTTTCTACCAAAACCCCGATGTGCTCTACATCTCGACCCATGGCTGGCC
GCTTTGGCCCAACTCAGGTCATTGGAAGGAGATGGGCGCGAACGCTGGATTGGGCACGACCCTTAACTTGCCATTACGCC
CATTAACTGGCGATATGGGTTTTCATCTGGTGTTTGAACAAGCGATTGCCCCAGCTATTCGGCGCTTCAAGCCTGAGTTA
TTGATCATCTCGGCGGGCTATGATGCGCATATTTACGACCCATTGGGGAATTTGGCACTCTCCACTGGCGGTTATGCCCA
GCTATCGTCGATCGTGTATAATTTAGCCGCCGAGTGCTGCGATGGACGCTTGGTGGGCTTGCTTGAGGGTGGTTACAACC
TCGAAGCCCTCGCTCAAAGCCTCACTGCAACGCTGCAAACATGGGTTTCTGGTCAGCCTGCCCCGATTTTCAATCAAGAA
GTCAGTCATACCCCAGAACCCGATGTTACCTGGCTGATCGAGCATCTCCGCCGCGAACATCCGCTTTTGAAGGGATGA

Upstream 100 bases:

>100_bases
ATAAATAAAATCTAGCCTAAATTCCATCGTTGGTTGGTTGCAGGCTTGCCAGCCCTCGATTAAGCTAGGCCTAGTATTGT
TCGCTGAGGAGCTTTCGCGT

Downstream 100 bases:

>100_bases
ATTATGAGGGCAGAAGGCAGAAGGCAGAAGGCAAAAATCAAAATAGGGATGAAGAACATAGAGCATAGAGGTACTGGATT
CTAGGGTTAACCACGGCGTG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSLALISHDHYLDHDQPEHPENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVHVPSHLPTLQRMAQFGDWADA
ETYILPDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRPPGHHATADQAMGFCLFNNAAIAAAFAQREYGLKRVAILDW
DVHHGNGTQDIFYQNPDVLYISTHGWPLWPNSGHWKEMGANAGLGTTLNLPLRPLTGDMGFHLVFEQAIAPAIRRFKPEL
LIISAGYDAHIYDPLGNLALSTGGYAQLSSIVYNLAAECCDGRLVGLLEGGYNLEALAQSLTATLQTWVSGQPAPIFNQE
VSHTPEPDVTWLIEHLRREHPLLKG

Sequences:

>Translated_345_residues
MSLALISHDHYLDHDQPEHPENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVHVPSHLPTLQRMAQFGDWADA
ETYILPDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRPPGHHATADQAMGFCLFNNAAIAAAFAQREYGLKRVAILDW
DVHHGNGTQDIFYQNPDVLYISTHGWPLWPNSGHWKEMGANAGLGTTLNLPLRPLTGDMGFHLVFEQAIAPAIRRFKPEL
LIISAGYDAHIYDPLGNLALSTGGYAQLSSIVYNLAAECCDGRLVGLLEGGYNLEALAQSLTATLQTWVSGQPAPIFNQE
VSHTPEPDVTWLIEHLRREHPLLKG
>Mature_344_residues
SLALISHDHYLDHDQPEHPENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVHVPSHLPTLQRMAQFGDWADAE
TYILPDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRPPGHHATADQAMGFCLFNNAAIAAAFAQREYGLKRVAILDWD
VHHGNGTQDIFYQNPDVLYISTHGWPLWPNSGHWKEMGANAGLGTTLNLPLRPLTGDMGFHLVFEQAIAPAIRRFKPELL
IISAGYDAHIYDPLGNLALSTGGYAQLSSIVYNLAAECCDGRLVGLLEGGYNLEALAQSLTATLQTWVSGQPAPIFNQEV
SHTPEPDVTWLIEHLRREHPLLKG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=334, Percent_Identity=38.0239520958084, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI13128864, Length=303, Percent_Identity=38.9438943894389, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI30795204, Length=342, Percent_Identity=32.4561403508772, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI17158039, Length=342, Percent_Identity=32.4561403508772, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI30795202, Length=342, Percent_Identity=32.4561403508772, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI153085395, Length=355, Percent_Identity=30.7042253521127, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI148539870, Length=360, Percent_Identity=32.7777777777778, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI169234807, Length=360, Percent_Identity=32.7777777777778, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI226529806, Length=337, Percent_Identity=35.0148367952522, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI62750349, Length=353, Percent_Identity=31.1614730878187, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI62750347, Length=353, Percent_Identity=31.1614730878187, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI13128860, Length=300, Percent_Identity=26, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI293336691, Length=268, Percent_Identity=26.4925373134328, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI8923769, Length=293, Percent_Identity=25.2559726962457, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI13128862, Length=297, Percent_Identity=26.2626262626263, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI262073092, Length=221, Percent_Identity=26.6968325791855, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI262073088, Length=184, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI209862883, Length=315, Percent_Identity=23.1746031746032, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI217272877, Length=210, Percent_Identity=24.7619047619048, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=315, Percent_Identity=34.9206349206349, Blast_Score=205, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI193206283, Length=315, Percent_Identity=34.9206349206349, Blast_Score=204, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17540332, Length=315, Percent_Identity=34.9206349206349, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI193209491, Length=335, Percent_Identity=32.2388059701493, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17537347, Length=329, Percent_Identity=33.1306990881459, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25154020, Length=302, Percent_Identity=31.1258278145695, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25154022, Length=302, Percent_Identity=30.4635761589404, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17508561, Length=318, Percent_Identity=28.3018867924528, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17534739, Length=297, Percent_Identity=26.5993265993266, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561978, Length=300, Percent_Identity=25.6666666666667, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324307, Length=355, Percent_Identity=35.7746478873239, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6325141, Length=375, Percent_Identity=25.6, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6323999, Length=296, Percent_Identity=25, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321244, Length=281, Percent_Identity=25.9786476868327, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=189, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24642144, Length=311, Percent_Identity=41.1575562700965, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI281360899, Length=311, Percent_Identity=41.1575562700965, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24642146, Length=311, Percent_Identity=41.1575562700965, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24642142, Length=311, Percent_Identity=41.1575562700965, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24641720, Length=342, Percent_Identity=34.7953216374269, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281360799, Length=342, Percent_Identity=34.7953216374269, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281360801, Length=342, Percent_Identity=34.7953216374269, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24657891, Length=300, Percent_Identity=27, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24644244, Length=303, Percent_Identity=27.0627062706271, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24649807, Length=300, Percent_Identity=25.3333333333333, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 37683; Mature: 37552

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLALISHDHYLDHDQPEHPENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVH
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEE
VPSHLPTLQRMAQFGDWADAETYILPDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRP
CCCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHCCCEEEEEHHHHCCCCCCCEEEECC
PGHHATADQAMGFCLFNNAAIAAAFAQREYGLKRVAILDWDVHHGNGTQDIFYQNPDVLY
CCCCCCHHHHCEEEEECCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEECCCCEEE
ISTHGWPLWPNSGHWKEMGANAGLGTTLNLPLRPLTGDMGFHLVFEQAIAPAIRRFKPEL
EECCCEECCCCCCCHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
LIISAGYDAHIYDPLGNLALSTGGYAQLSSIVYNLAAECCDGRLVGLLEGGYNLEALAQS
EEEECCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
LTATLQTWVSGQPAPIFNQEVSHTPEPDVTWLIEHLRREHPLLKG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLALISHDHYLDHDQPEHPENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVH
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEE
VPSHLPTLQRMAQFGDWADAETYILPDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRP
CCCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHCCCEEEEEHHHHCCCCCCCEEEECC
PGHHATADQAMGFCLFNNAAIAAAFAQREYGLKRVAILDWDVHHGNGTQDIFYQNPDVLY
CCCCCCHHHHCEEEEECCCHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEECCCCEEE
ISTHGWPLWPNSGHWKEMGANAGLGTTLNLPLRPLTGDMGFHLVFEQAIAPAIRRFKPEL
EECCCEECCCCCCCHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
LIISAGYDAHIYDPLGNLALSTGGYAQLSSIVYNLAAECCDGRLVGLLEGGYNLEALAQS
EEEECCCCCEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHH
LTATLQTWVSGQPAPIFNQEVSHTPEPDVTWLIEHLRREHPLLKG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]