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The map label for this gene is kynB [H]

Identifier: 159896592

GI number: 159896592

Start: 74258

End: 74899

Strand: Reverse

Name: kynB [H]

Synonym: Haur_0059

Alternate gene names: 159896592

Gene position: 74899-74258 (Counterclockwise)

Preceding gene: 159896593

Following gene: 159896591

Centisome position: 1.18

GC content: 51.71

Gene sequence:

>642_bases
ATGGCCCACTTGATCGATATTAGCGTTCCGATTTCGCCAGCCCTGCCGGTTTGGGAAGGCGACCCGCCGATTGAACAAAA
ACGCGCCGCCGATATGAACAAAGGCGATATTTGTAATGTAACCCGCCTTAACACTGGGGTGCATATTGGCACGCACGTTG
ATGCACCGCTGCACTTTATCAACAACGATTTGGCAGTTGAAAGCTTGGAGCTTGATCGGTTTGTTGGTGATTGTTATGTA
GTGGAATTGATTGGTACTGGGCCAATTACTGGTGCTGAACTGGCCGCCGCGAATGTGCCTAGCGATTGTACGCGTCTCTT
GCTCAAAACCAGCAATTCGGCCTTTTGGCAAGAAGAACCCTTGCGTTTCCATCGCGATTTTCGCGCACTCGACAGTAGTG
CGGCTCGTTGGGTGATTGAGCACGATTTGCGCTTGATTGCGATCGATTATCTTTCAATCGAGCCATTTGAAGCCGAGCCA
GGCAACCCTACTCACTGTATTTTGCTCGGCGGTCGGGTGGCAATCTTAGAGGGCATCAATTTAACCGAGGTCGCGCCTGG
CCCATACAATTTGCTCTGCTTGCCATTGAAAATTCTGGGCAGCGATGGTGCTCCAGCTCGGGCCGTGCTTCAACCACGCT
AA

Upstream 100 bases:

>100_bases
CCTGCTGGCTGCCTGCTATTTTAGAATCATTTTTGTGAGACAATGGAAGCAGCTATTCTAGAGGTATGTGCAGCATACCT
TGCCGTTGAAGGAGCCACCC

Downstream 100 bases:

>100_bases
TTGCGCTTGCTACAGCCAGTTTGTGGCAATCCTGGGAGTTTTACTATGTTGCATACCATTGATCTTGTGGTTGAGCCGGT
AACCGATCCACGGATTACGC

Product: cyclase family protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MAHLIDISVPISPALPVWEGDPPIEQKRAADMNKGDICNVTRLNTGVHIGTHVDAPLHFINNDLAVESLELDRFVGDCYV
VELIGTGPITGAELAAANVPSDCTRLLLKTSNSAFWQEEPLRFHRDFRALDSSAARWVIEHDLRLIAIDYLSIEPFEAEP
GNPTHCILLGGRVAILEGINLTEVAPGPYNLLCLPLKILGSDGAPARAVLQPR

Sequences:

>Translated_213_residues
MAHLIDISVPISPALPVWEGDPPIEQKRAADMNKGDICNVTRLNTGVHIGTHVDAPLHFINNDLAVESLELDRFVGDCYV
VELIGTGPITGAELAAANVPSDCTRLLLKTSNSAFWQEEPLRFHRDFRALDSSAARWVIEHDLRLIAIDYLSIEPFEAEP
GNPTHCILLGGRVAILEGINLTEVAPGPYNLLCLPLKILGSDGAPARAVLQPR
>Mature_212_residues
AHLIDISVPISPALPVWEGDPPIEQKRAADMNKGDICNVTRLNTGVHIGTHVDAPLHFINNDLAVESLELDRFVGDCYVV
ELIGTGPITGAELAAANVPSDCTRLLLKTSNSAFWQEEPLRFHRDFRALDSSAARWVIEHDLRLIAIDYLSIEPFEAEPG
NPTHCILLGGRVAILEGINLTEVAPGPYNLLCLPLKILGSDGAPARAVLQPR

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 23166; Mature: 23035

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLIDISVPISPALPVWEGDPPIEQKRAADMNKGDICNVTRLNTGVHIGTHVDAPLHFI
CCEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCEEC
NNDLAVESLELDRFVGDCYVVELIGTGPITGAELAAANVPSDCTRLLLKTSNSAFWQEEP
CCCCEEEEEHHHHHCCCEEEEEEECCCCCCCCHHEECCCCHHHHHHHHHCCCCCCCCCCH
LRFHRDFRALDSSAARWVIEHDLRLIAIDYLSIEPFEAEPGNPTHCILLGGRVAILEGIN
HHHHHHHHHHHHHHHEEEEECCEEEEEEEEEEECCCCCCCCCCCEEEEECCEEEEEECCC
LTEVAPGPYNLLCLPLKILGSDGAPARAVLQPR
EEEECCCCCEEEEEEEEEECCCCCCCEEEECCC
>Mature Secondary Structure 
AHLIDISVPISPALPVWEGDPPIEQKRAADMNKGDICNVTRLNTGVHIGTHVDAPLHFI
CEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCEEC
NNDLAVESLELDRFVGDCYVVELIGTGPITGAELAAANVPSDCTRLLLKTSNSAFWQEEP
CCCCEEEEEHHHHHCCCEEEEEEECCCCCCCCHHEECCCCHHHHHHHHHCCCCCCCCCCH
LRFHRDFRALDSSAARWVIEHDLRLIAIDYLSIEPFEAEPGNPTHCILLGGRVAILEGIN
HHHHHHHHHHHHHHHEEEEECCEEEEEEEEEEECCCCCCCCCCCEEEEECCEEEEEECCC
LTEVAPGPYNLLCLPLKILGSDGAPARAVLQPR
EEEECCCCCEEEEEEEEEECCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA