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The map label for this gene is rsbRA [H]

Identifier: 159896585

GI number: 159896585

Start: 67020

End: 68072

Strand: Direct

Name: rsbRA [H]

Synonym: Haur_0052

Alternate gene names: 159896585

Gene position: 67020-68072 (Clockwise)

Preceding gene: 159896584

Following gene: 159896586

Centisome position: 1.06

GC content: 39.79

Gene sequence:

>1053_bases
ATGTCAGCAGATAAATCGATTGGGCAATCGTATCGCCAAATTCAACAAGAATTATTGAATAAAATTCTCCGTACTATTTT
AACGTCAACCAGTGTTCTATTTGTGGTGATGCTAATCGCGCTGGCGTTTCCCTCAATTCGTACAATTCCCTTTATTATCA
TGACATTGGTAGCATTTACTGGCGTTGTGGTTATTTCAATCAGTCAATATTGGATTCGCAAAGGCTACCCACGCCGTGGA
GCCTTTTTCTTTATTATGAGTTCGATTCTCTTAGGCGCAATGTTATCAATTGTGTTTAGCATCCCTTCATTTATTGCCCT
CGTTTCAATTTTGCTGATTATTATTAGTGCAATATTAATTGGTTTTCGTTATACAATCTATCCTTTGATGCTATCAATAT
GTTCATCGATATTATTGATGCTTGCTGATTATAATCAATGGTTTGCAGCACTTCAATTCGATAATACAACGCTTTTATCA
TTAATTATTCAAATTATTGTCGTATTAAGTATGTTGATTGTCACTGCCTTGGTGATTAATATGGCGGTCAAGCGCTTGGA
AGAAAGTGCCAATGAGGCATTTTTGCGGGCACGAGATGCTGAAGAAGCTCGCTTCGATCAAATTGCCCTCAATGACCAAC
TGCACCACGACAACCTTGAAAAGCAAAAATTACTTGATGTGATTGCAGCCCTCGAAACGCCAGCAATTCCAATTTTAGCT
GATACCGTAGTTATTCCCATTGTCGGCTATGTTTCTGATGATCGTTTGGAGAAAATTCAAAAACTTGTGCTTGAACATAT
TCATCGTGAGCGGCTGCAAACCGTATTGCTTGATATCACTGGCGTTACCAGTGTTGATCAGAGCTTTGCCCAAGGCTTAA
AGCGTTTAGTCCAAGCAATTTATGTCTTGGGCGCAAAAGTCTTTCTGACTGGCATTCAACCAAAAACGGCCCATATATTC
GTCGATTTAGATCTGCATACCGCCTTACCATCAACCTACGCCACAATTGCTGATGCAATCGAAGATTTAACCGCCCTACA
TCGCAAGGGGTAA

Upstream 100 bases:

>100_bases
GCTGTCATCAACTTGCCACATTTGTAACTACCATTGCAACAAGCACTGGAGTATAATAGCCCCAACTCAGCATCAACCTA
GCTAGGTTTTGGGGGCAGTT

Downstream 100 bases:

>100_bases
TCATTCAATGATTCAAGCCGATGATCGACCGATATTTGCATGAACCAGCCAATCTATCTTGAATGGGCCAAACAACAGCC
TGCCACTGCGATTTTGAGCA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSADKSIGQSYRQIQQELLNKILRTILTSTSVLFVVMLIALAFPSIRTIPFIIMTLVAFTGVVVISISQYWIRKGYPRRG
AFFFIMSSILLGAMLSIVFSIPSFIALVSILLIIISAILIGFRYTIYPLMLSICSSILLMLADYNQWFAALQFDNTTLLS
LIIQIIVVLSMLIVTALVINMAVKRLEESANEAFLRARDAEEARFDQIALNDQLHHDNLEKQKLLDVIAALETPAIPILA
DTVVIPIVGYVSDDRLEKIQKLVLEHIHRERLQTVLLDITGVTSVDQSFAQGLKRLVQAIYVLGAKVFLTGIQPKTAHIF
VDLDLHTALPSTYATIADAIEDLTALHRKG

Sequences:

>Translated_350_residues
MSADKSIGQSYRQIQQELLNKILRTILTSTSVLFVVMLIALAFPSIRTIPFIIMTLVAFTGVVVISISQYWIRKGYPRRG
AFFFIMSSILLGAMLSIVFSIPSFIALVSILLIIISAILIGFRYTIYPLMLSICSSILLMLADYNQWFAALQFDNTTLLS
LIIQIIVVLSMLIVTALVINMAVKRLEESANEAFLRARDAEEARFDQIALNDQLHHDNLEKQKLLDVIAALETPAIPILA
DTVVIPIVGYVSDDRLEKIQKLVLEHIHRERLQTVLLDITGVTSVDQSFAQGLKRLVQAIYVLGAKVFLTGIQPKTAHIF
VDLDLHTALPSTYATIADAIEDLTALHRKG
>Mature_349_residues
SADKSIGQSYRQIQQELLNKILRTILTSTSVLFVVMLIALAFPSIRTIPFIIMTLVAFTGVVVISISQYWIRKGYPRRGA
FFFIMSSILLGAMLSIVFSIPSFIALVSILLIIISAILIGFRYTIYPLMLSICSSILLMLADYNQWFAALQFDNTTLLSL
IIQIIVVLSMLIVTALVINMAVKRLEESANEAFLRARDAEEARFDQIALNDQLHHDNLEKQKLLDVIAALETPAIPILAD
TVVIPIVGYVSDDRLEKIQKLVLEHIHRERLQTVLLDITGVTSVDQSFAQGLKRLVQAIYVLGAKVFLTGIQPKTAHIFV
DLDLHTALPSTYATIADAIEDLTALHRKG

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39009; Mature: 38878

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADKSIGQSYRQIQQELLNKILRTILTSTSVLFVVMLIALAFPSIRTIPFIIMTLVAFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GVVVISISQYWIRKGYPRRGAFFFIMSSILLGAMLSIVFSIPSFIALVSILLIIISAILI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFRYTIYPLMLSICSSILLMLADYNQWFAALQFDNTTLLSLIIQIIVVLSMLIVTALVIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MAVKRLEESANEAFLRARDAEEARFDQIALNDQLHHDNLEKQKLLDVIAALETPAIPILA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
DTVVIPIVGYVSDDRLEKIQKLVLEHIHRERLQTVLLDITGVTSVDQSFAQGLKRLVQAI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YVLGAKVFLTGIQPKTAHIFVDLDLHTALPSTYATIADAIEDLTALHRKG
HHHHHHHHHCCCCCCEEEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SADKSIGQSYRQIQQELLNKILRTILTSTSVLFVVMLIALAFPSIRTIPFIIMTLVAFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GVVVISISQYWIRKGYPRRGAFFFIMSSILLGAMLSIVFSIPSFIALVSILLIIISAILI
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFRYTIYPLMLSICSSILLMLADYNQWFAALQFDNTTLLSLIIQIIVVLSMLIVTALVIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MAVKRLEESANEAFLRARDAEEARFDQIALNDQLHHDNLEKQKLLDVIAALETPAIPILA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
DTVVIPIVGYVSDDRLEKIQKLVLEHIHRERLQTVLLDITGVTSVDQSFAQGLKRLVQAI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YVLGAKVFLTGIQPKTAHIFVDLDLHTALPSTYATIADAIEDLTALHRKG
HHHHHHHHHCCCCCCEEEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]