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The map label for this gene is hisC [H]

Identifier: 159896586

GI number: 159896586

Start: 68112

End: 69212

Strand: Direct

Name: hisC [H]

Synonym: Haur_0053

Alternate gene names: 159896586

Gene position: 68112-69212 (Clockwise)

Preceding gene: 159896585

Following gene: 159896587

Centisome position: 1.07

GC content: 51.59

Gene sequence:

>1101_bases
ATGAACCAGCCAATCTATCTTGAATGGGCCAAACAACAGCCTGCCACTGCGATTTTGAGCAATAGCAGCGTTTACTTGCC
CAGTGTGCGAAACGCAATTCAGCAACAGTTAGCTGATGCTGCGTGGTTTGCAGCCGCCCAACAAGCCAACCCTTGGGGAT
ATCCCAGCCTTCAGCAAGCCTTGCAAGCATGGCATCGTAGTAGCTATTCGCCGTTGATTGTGGCTGGCGCTTCGAGTGCC
TTGGCGGTGGTATGCCAAGCCTTGTTGCAACCAGGCGATCATGCTCTGATCGAAACCCCGCAATATGAGCCATTCAGCCG
TTGTGTCGCCGCCCGAGGAGCCACTTGGAGCGCTTGGCCACGCCATCCGCAGAGCTTTGAATTGCAATTAGACCAATTGG
CCAGCGGCATCACGCCTCGGACCAAGCTGTTGTTAATCAGCAACTTGCATAACCCCAGCAGCACACTGAGCAACCAATCC
CAATTGCTTCGCTTGCAACAAACCCTTACTCAAGCCACAGATACGCTTGGAATTGCTCCGATCACGATGGTGGTTGATGA
GATTTATTGGCATTTGGTAGCACAAGCTGAGTTTCGTTCGGTAGCCGAACTTGGGCCGCAGTGGATCGGGATCAACAGCC
TGTCGAAGGTGTATGGGCTAAGCATGCTGCGTTGTGGCTGGATTATGGCCGCGCCCCAGCTGCTCGATCAACTACGCCCA
GCTTATCTCGATTTGATTAACATTGGTTCGCCGTTGACTGAATATTTGGCGGCGAGCATTATTGAACAATTGGCCAATTA
TCAAACTGCTGCCCAAGCCCATGTTGCCGTCAATCGCCAAATAGTGCAACGCTATATGCAGCCGTTGCTTGAGCGTGAAT
TGATCAACGGTGTAATTCCTGCGGCGGGCTGCACTTATTTTCCCAAAATCATGCTTGATCAAACCCAAATTGACCACGTA
GCCCAACAAACTGGCTGTGTGCCTGGGCGGTTTTTCGGCTCGGCCTATCAGCAGCAGCTACGAATTGGCTTTGGCGGCCC
GAGTAATTTAATTGAAGCAGCCTTGAAACCCTTTACCCAAACAATCCTACCACTTCAATAA

Upstream 100 bases:

>100_bases
AACCTACGCCACAATTGCTGATGCAATCGAAGATTTAACCGCCCTACATCGCAAGGGGTAATCATTCAATGATTCAAGCC
GATGATCGACCGATATTTGC

Downstream 100 bases:

>100_bases
TAGTCAATAAACTCCGGTTCAACCCGCTATTTGTAGGATACTTCTGCAAATGCTATACTACTAAGACAGCTACGTTGGTT
TGTACGACCAACATCAAGCC

Product: class I and II aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNQPIYLEWAKQQPATAILSNSSVYLPSVRNAIQQQLADAAWFAAAQQANPWGYPSLQQALQAWHRSSYSPLIVAGASSA
LAVVCQALLQPGDHALIETPQYEPFSRCVAARGATWSAWPRHPQSFELQLDQLASGITPRTKLLLISNLHNPSSTLSNQS
QLLRLQQTLTQATDTLGIAPITMVVDEIYWHLVAQAEFRSVAELGPQWIGINSLSKVYGLSMLRCGWIMAAPQLLDQLRP
AYLDLINIGSPLTEYLAASIIEQLANYQTAAQAHVAVNRQIVQRYMQPLLERELINGVIPAAGCTYFPKIMLDQTQIDHV
AQQTGCVPGRFFGSAYQQQLRIGFGGPSNLIEAALKPFTQTILPLQ

Sequences:

>Translated_366_residues
MNQPIYLEWAKQQPATAILSNSSVYLPSVRNAIQQQLADAAWFAAAQQANPWGYPSLQQALQAWHRSSYSPLIVAGASSA
LAVVCQALLQPGDHALIETPQYEPFSRCVAARGATWSAWPRHPQSFELQLDQLASGITPRTKLLLISNLHNPSSTLSNQS
QLLRLQQTLTQATDTLGIAPITMVVDEIYWHLVAQAEFRSVAELGPQWIGINSLSKVYGLSMLRCGWIMAAPQLLDQLRP
AYLDLINIGSPLTEYLAASIIEQLANYQTAAQAHVAVNRQIVQRYMQPLLERELINGVIPAAGCTYFPKIMLDQTQIDHV
AQQTGCVPGRFFGSAYQQQLRIGFGGPSNLIEAALKPFTQTILPLQ
>Mature_366_residues
MNQPIYLEWAKQQPATAILSNSSVYLPSVRNAIQQQLADAAWFAAAQQANPWGYPSLQQALQAWHRSSYSPLIVAGASSA
LAVVCQALLQPGDHALIETPQYEPFSRCVAARGATWSAWPRHPQSFELQLDQLASGITPRTKLLLISNLHNPSSTLSNQS
QLLRLQQTLTQATDTLGIAPITMVVDEIYWHLVAQAEFRSVAELGPQWIGINSLSKVYGLSMLRCGWIMAAPQLLDQLRP
AYLDLINIGSPLTEYLAASIIEQLANYQTAAQAHVAVNRQIVQRYMQPLLERELINGVIPAAGCTYFPKIMLDQTQIDHV
AQQTGCVPGRFFGSAYQQQLRIGFGGPSNLIEAALKPFTQTILPLQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786816, Length=222, Percent_Identity=23.8738738738739, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788627, Length=253, Percent_Identity=27.6679841897233, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40310; Mature: 40310

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPIYLEWAKQQPATAILSNSSVYLPSVRNAIQQQLADAAWFAAAQQANPWGYPSLQQA
CCCCEEEEECCCCCCCEEECCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LQAWHRSSYSPLIVAGASSALAVVCQALLQPGDHALIETPQYEPFSRCVAARGATWSAWP
HHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCCCCC
RHPQSFELQLDQLASGITPRTKLLLISNLHNPSSTLSNQSQLLRLQQTLTQATDTLGIAP
CCCCHHHHHHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ITMVVDEIYWHLVAQAEFRSVAELGPQWIGINSLSKVYGLSMLRCGWIMAAPQLLDQLRP
HHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLDLINIGSPLTEYLAASIIEQLANYQTAAQAHVAVNRQIVQRYMQPLLERELINGVIP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAGCTYFPKIMLDQTQIDHVAQQTGCVPGRFFGSAYQQQLRIGFGGPSNLIEAALKPFTQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TILPLQ
HHCCCC
>Mature Secondary Structure
MNQPIYLEWAKQQPATAILSNSSVYLPSVRNAIQQQLADAAWFAAAQQANPWGYPSLQQA
CCCCEEEEECCCCCCCEEECCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LQAWHRSSYSPLIVAGASSALAVVCQALLQPGDHALIETPQYEPFSRCVAARGATWSAWP
HHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCCCCC
RHPQSFELQLDQLASGITPRTKLLLISNLHNPSSTLSNQSQLLRLQQTLTQATDTLGIAP
CCCCHHHHHHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ITMVVDEIYWHLVAQAEFRSVAELGPQWIGINSLSKVYGLSMLRCGWIMAAPQLLDQLRP
HHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLDLINIGSPLTEYLAASIIEQLANYQTAAQAHVAVNRQIVQRYMQPLLERELINGVIP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAGCTYFPKIMLDQTQIDHVAQQTGCVPGRFFGSAYQQQLRIGFGGPSNLIEAALKPFTQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TILPLQ
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA