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The map label for this gene is aroF [H]

Identifier: 15922602

GI number: 15922602

Start: 2279918

End: 2280910

Strand: Direct

Name: aroF [H]

Synonym: ST2271

Alternate gene names: 15922602

Gene position: 2279918-2280910 (Clockwise)

Preceding gene: 15922601

Following gene: 15922603

Centisome position: 84.61

GC content: 34.54

Gene sequence:

>993_bases
ATGATTTTCATATTAAGAGAAAAAGCGGATTATTCTGTATTAAGAGAAAAATTACAAGATTCATCTGCCTCTTATAAGTT
TCTAGATCTTTATGGTAAAAAAATTGTAGTAGCATGGCCAGACGAATATGTATCAAATATTGTAGATCCAAGTATTGAAA
TAACAGTAAAACCGAAAAAGCCTTATCAATTAGTGAGTAATGAATGGAAAAAAGAACCAACAAAAGTTAAAGTGAAAGAT
GCTGAAATTGGAGATAATAAAGTAATAGTAGCCGCTGGACCTTGTGCTGTTGAAAACGAAGAACAAGTTTTAACAGTTGC
TAAGGCAGTAAAGAGGGCTGGAGCATCGATTTTAAGAGGCGGAGCATATAAACCTAGGACTAGTCCTTATTCTTTTCAAG
GTCTAGGAGAAGAAGGTTTGAAGATATTGAAAAAAGCATCAGAAGAAACTGGTTTACCTATAGTTTCTGAGATTATGGAC
ACTAGAGATATAGAAATTTTTAAAAAATATGTAGATATGATGCAAATAGGGGCAAGAAATGCACAGAACTTTGACCTACT
AAAAGAGGTTGGAAAAGCTGGTTTACCAGTATTACTAAAAAGAGGAATGGCAAATACTGTTGAAGAGTGGTTACTTACAG
CTGAATATATATTATTAGAAGGGAATGGAAATGTAGTTTTATGTGAAAGAGGTATAAGAACTTTTGAAAAAGCTACGAGA
TTTACAATAGATATAGGAGGAATGGTTGCGGCTAAATTACAGACTCACTTACCAATTTGTGCTGATCCTAGTCATCCAGC
AGGTAAAAGAGAACTCGTTCATTCATTAGCTTTGGCAGCAGTAGCTGCTGGTGCAGATATGTTACTTATTGAAGTTCATC
CTCATCCAGAAAAAGCATTAAGTGATTCAGAACAACAATTAACCCCAGAGTCCTTTGAAGTATTAATGAATAGGATTAGG
GCATTAGCTAATGCACTAGGTAGAACTGCATGA

Upstream 100 bases:

>100_bases
AGTAATTTTAGAAATACAAAAATCAAACCCTTATGCTTATAAAGTTAGAGATATAGGAGTAAACGAATTACAAAAAATAA
AAGAAGAATTGGGTGGTTAA

Downstream 100 bases:

>100_bases
GGATAGTAAATGAGAATTTATGTAATAATGAGATTTCTATAGTAATTGGAAAAGGAGCCTTATCTGCATTAGAGGAATTA
AAAGATAAGAAGGTTGCCCT

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIFILREKADYSVLREKLQDSSASYKFLDLYGKKIVVAWPDEYVSNIVDPSIEITVKPKKPYQLVSNEWKKEPTKVKVKD
AEIGDNKVIVAAGPCAVENEEQVLTVAKAVKRAGASILRGGAYKPRTSPYSFQGLGEEGLKILKKASEETGLPIVSEIMD
TRDIEIFKKYVDMMQIGARNAQNFDLLKEVGKAGLPVLLKRGMANTVEEWLLTAEYILLEGNGNVVLCERGIRTFEKATR
FTIDIGGMVAAKLQTHLPICADPSHPAGKRELVHSLALAAVAAGADMLLIEVHPHPEKALSDSEQQLTPESFEVLMNRIR
ALANALGRTA

Sequences:

>Translated_330_residues
MIFILREKADYSVLREKLQDSSASYKFLDLYGKKIVVAWPDEYVSNIVDPSIEITVKPKKPYQLVSNEWKKEPTKVKVKD
AEIGDNKVIVAAGPCAVENEEQVLTVAKAVKRAGASILRGGAYKPRTSPYSFQGLGEEGLKILKKASEETGLPIVSEIMD
TRDIEIFKKYVDMMQIGARNAQNFDLLKEVGKAGLPVLLKRGMANTVEEWLLTAEYILLEGNGNVVLCERGIRTFEKATR
FTIDIGGMVAAKLQTHLPICADPSHPAGKRELVHSLALAAVAAGADMLLIEVHPHPEKALSDSEQQLTPESFEVLMNRIR
ALANALGRTA
>Mature_330_residues
MIFILREKADYSVLREKLQDSSASYKFLDLYGKKIVVAWPDEYVSNIVDPSIEITVKPKKPYQLVSNEWKKEPTKVKVKD
AEIGDNKVIVAAGPCAVENEEQVLTVAKAVKRAGASILRGGAYKPRTSPYSFQGLGEEGLKILKKASEETGLPIVSEIMD
TRDIEIFKKYVDMMQIGARNAQNFDLLKEVGKAGLPVLLKRGMANTVEEWLLTAEYILLEGNGNVVLCERGIRTFEKATR
FTIDIGGMVAAKLQTHLPICADPSHPAGKRELVHSLALAAVAAGADMLLIEVHPHPEKALSDSEQQLTPESFEVLMNRIR
ALANALGRTA

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36342; Mature: 36342

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFILREKADYSVLREKLQDSSASYKFLDLYGKKIVVAWPDEYVSNIVDPSIEITVKPKK
CEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEEEECCHHHHHHHCCCCEEEEECCCC
PYQLVSNEWKKEPTKVKVKDAEIGDNKVIVAAGPCAVENEEQVLTVAKAVKRAGASILRG
CHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHCC
GAYKPRTSPYSFQGLGEEGLKILKKASEETGLPIVSEIMDTRDIEIFKKYVDMMQIGARN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC
AQNFDLLKEVGKAGLPVLLKRGMANTVEEWLLTAEYILLEGNGNVVLCERGIRTFEKATR
CCCHHHHHHHCCCCCHHHHHCCHHHHHHHHHHEEEEEEEECCCCEEEECCHHHHHHHHHE
FTIDIGGMVAAKLQTHLPICADPSHPAGKRELVHSLALAAVAAGADMLLIEVHPHPEKAL
EEEEECCHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
SDSEQQLTPESFEVLMNRIRALANALGRTA
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIFILREKADYSVLREKLQDSSASYKFLDLYGKKIVVAWPDEYVSNIVDPSIEITVKPKK
CEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEEEECCHHHHHHHCCCCEEEEECCCC
PYQLVSNEWKKEPTKVKVKDAEIGDNKVIVAAGPCAVENEEQVLTVAKAVKRAGASILRG
CHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCHHHHCC
GAYKPRTSPYSFQGLGEEGLKILKKASEETGLPIVSEIMDTRDIEIFKKYVDMMQIGARN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC
AQNFDLLKEVGKAGLPVLLKRGMANTVEEWLLTAEYILLEGNGNVVLCERGIRTFEKATR
CCCHHHHHHHCCCCCHHHHHCCHHHHHHHHHHEEEEEEEECCCCEEEECCHHHHHHHHHE
FTIDIGGMVAAKLQTHLPICADPSHPAGKRELVHSLALAAVAAGADMLLIEVHPHPEKAL
EEEEECCHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
SDSEQQLTPESFEVLMNRIRALANALGRTA
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]