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The map label for this gene is tyrA [H]

Identifier: 15922601

GI number: 15922601

Start: 2278892

End: 2279917

Strand: Direct

Name: tyrA [H]

Synonym: ST2270

Alternate gene names: 15922601

Gene position: 2278892-2279917 (Clockwise)

Preceding gene: 15922600

Following gene: 15922602

Centisome position: 84.57

GC content: 28.95

Gene sequence:

>1026_bases
ATGAGTGCTGAAATTGATGAATTACGAAAAGAAATAGAAGCTATAGATAAACAAATATTAGAATTATTATCAAGAAGATT
AAAAATTTCTGCTAAAATAGGAGAGATTAAGAGTAGAATAGGCAAAGATGTTACAGATGAGAAAAGAGAGCAGAAAGTCA
GAGAGTATTGGTACAATTACGCTAGAAATTTAGGAATTCCAGATTCTATGGTAGAGAGTATTTTACCTATTTTATTTTCT
TATTCAAAGATGGTTCAAATCAACCCTGGAAAAAAGAAAAACATTACAGTTATTGGATATGGTGGAATGGCAAGATCACT
AATTTCTTTGTTCTCGTTAGTTGGTCATAATGTGGTCGTAACTGGTAGAAACAAAGAGAAAGCTGAAAGATTAGCTTCTG
AATTTAAAGTAGTTTATATGGACTTAGATTCTGCCTTAAATTGGGGAGAGTACATAATTTTAGCCCTTTCTCCTTCTTCT
TTTGATTACATTCTAAGAATTTCACCTAAATTCACAAGTAAAGTAGTAATGGATATTTTTTCTTCTAAAAATGAGATTTT
TAAGGAATTAGAAAAATTATCTGAAATTTATTCTTTTAATTATATCTCTACTCATCCACTATTTGGTCCTATAACTTATC
CAGTAGGAGAAAGAATAGTGATTATTCCTTCAAAAACATCCAAAAATGTTAATGAAATAGTAAACTTCTGGAGAGAATGT
GGACTAAATACAACTGTTTCCACAGTTGAAGAACATGAAAAAGCCATGGCTATAGTACAAGTTTTAGCTCATTTTTACAT
TTTAGGTTTACACAGGAGCATAGATGAATTAAGAAAGGAGTTAGGTATAGAAAATCTTTCCAATTTTTATACGACCAATT
TTAAAGAATTAAATAAAATTATAGAAAAAGTAAGCAACATTCTTCCAGTAATTTTAGAAATACAAAAATCAAACCCTTAT
GCTTATAAAGTTAGAGATATAGGAGTAAACGAATTACAAAAAATAAAAGAAGAATTGGGTGGTTAA

Upstream 100 bases:

>100_bases
TACCTTTGGAAGATCTGCTAGGAGCGAGAGAGATTTACTTGATTTCTATGGTATAAATTATAAGTCTATCTTAAATGCGG
TTATGGAATTAGTGAAGTGA

Downstream 100 bases:

>100_bases
ATGATTTTCATATTAAGAGAAAAAGCGGATTATTCTGTATTAAGAGAAAAATTACAAGATTCATCTGCCTCTTATAAGTT
TCTAGATCTTTATGGTAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSAEIDELRKEIEAIDKQILELLSRRLKISAKIGEIKSRIGKDVTDEKREQKVREYWYNYARNLGIPDSMVESILPILFS
YSKMVQINPGKKKNITVIGYGGMARSLISLFSLVGHNVVVTGRNKEKAERLASEFKVVYMDLDSALNWGEYIILALSPSS
FDYILRISPKFTSKVVMDIFSSKNEIFKELEKLSEIYSFNYISTHPLFGPITYPVGERIVIIPSKTSKNVNEIVNFWREC
GLNTTVSTVEEHEKAMAIVQVLAHFYILGLHRSIDELRKELGIENLSNFYTTNFKELNKIIEKVSNILPVILEIQKSNPY
AYKVRDIGVNELQKIKEELGG

Sequences:

>Translated_341_residues
MSAEIDELRKEIEAIDKQILELLSRRLKISAKIGEIKSRIGKDVTDEKREQKVREYWYNYARNLGIPDSMVESILPILFS
YSKMVQINPGKKKNITVIGYGGMARSLISLFSLVGHNVVVTGRNKEKAERLASEFKVVYMDLDSALNWGEYIILALSPSS
FDYILRISPKFTSKVVMDIFSSKNEIFKELEKLSEIYSFNYISTHPLFGPITYPVGERIVIIPSKTSKNVNEIVNFWREC
GLNTTVSTVEEHEKAMAIVQVLAHFYILGLHRSIDELRKELGIENLSNFYTTNFKELNKIIEKVSNILPVILEIQKSNPY
AYKVRDIGVNELQKIKEELGG
>Mature_340_residues
SAEIDELRKEIEAIDKQILELLSRRLKISAKIGEIKSRIGKDVTDEKREQKVREYWYNYARNLGIPDSMVESILPILFSY
SKMVQINPGKKKNITVIGYGGMARSLISLFSLVGHNVVVTGRNKEKAERLASEFKVVYMDLDSALNWGEYIILALSPSSF
DYILRISPKFTSKVVMDIFSSKNEIFKELEKLSEIYSFNYISTHPLFGPITYPVGERIVIIPSKTSKNVNEIVNFWRECG
LNTTVSTVEEHEKAMAIVQVLAHFYILGLHRSIDELRKELGIENLSNFYTTNFKELNKIIEKVSNILPVILEIQKSNPYA
YKVRDIGVNELQKIKEELGG

Specific function: Tyrosine biosynthesis [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

Organism=Escherichia coli, GI1788952, Length=285, Percent_Identity=25.9649122807018, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR008244
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR011277
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01817 CM_2; PF02153 PDH [H]

EC number: =5.4.99.5; =1.3.1.12 [H]

Molecular weight: Translated: 39053; Mature: 38922

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEIDELRKEIEAIDKQILELLSRRLKISAKIGEIKSRIGKDVTDEKREQKVREYWYNY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ARNLGIPDSMVESILPILFSYSKMVQINPGKKKNITVIGYGGMARSLISLFSLVGHNVVV
HHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEE
TGRNKEKAERLASEFKVVYMDLDSALNWGEYIILALSPSSFDYILRISPKFTSKVVMDIF
ECCCHHHHHHHHHHHEEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHH
SSKNEIFKELEKLSEIYSFNYISTHPLFGPITYPVGERIVIIPSKTSKNVNEIVNFWREC
HCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHC
GLNTTVSTVEEHEKAMAIVQVLAHFYILGLHRSIDELRKELGIENLSNFYTTNFKELNKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
IEKVSNILPVILEIQKSNPYAYKVRDIGVNELQKIKEELGG
HHHHHHHHHHHEEEECCCCEEEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
SAEIDELRKEIEAIDKQILELLSRRLKISAKIGEIKSRIGKDVTDEKREQKVREYWYNY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ARNLGIPDSMVESILPILFSYSKMVQINPGKKKNITVIGYGGMARSLISLFSLVGHNVVV
HHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEE
TGRNKEKAERLASEFKVVYMDLDSALNWGEYIILALSPSSFDYILRISPKFTSKVVMDIF
ECCCHHHHHHHHHHHEEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHH
SSKNEIFKELEKLSEIYSFNYISTHPLFGPITYPVGERIVIIPSKTSKNVNEIVNFWREC
HCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHC
GLNTTVSTVEEHEKAMAIVQVLAHFYILGLHRSIDELRKELGIENLSNFYTTNFKELNKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
IEKVSNILPVILEIQKSNPYAYKVRDIGVNELQKIKEELGG
HHHHHHHHHHHEEEECCCCEEEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512561 [H]