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The map label for this gene is pgaC [H]

Identifier: 15920740

GI number: 15920740

Start: 520096

End: 521355

Strand: Reverse

Name: pgaC [H]

Synonym: ST0523

Alternate gene names: 15920740

Gene position: 521355-520096 (Counterclockwise)

Preceding gene: 15920741

Following gene: 15920732

Centisome position: 19.35

GC content: 28.57

Gene sequence:

>1260_bases
ATGAATATTTTTTCTTTGTTACTAATTTTATCTGCTATATTACCATCTGTTTGGAATCTTTTACAGTCTTATTATTACTC
AAAACATCAAATTAACGTTTACGAACCACAAAATAAATCTCAAAAGGGGTTTAGTATAATTGTGGCTGAAAAGAATGAAA
GTAAAAAAACTATAGAGGGTTTAATACATAATCTACTAGATATTAATTACGAGAAGTACGAAATTATAATTATTTCCGAT
GATCCTAAAGAAAAATTTGAAGAAAAATATCGTGAATACATGAACATAGAAAAATTAAAAATCCTTCATAGAAATAATCC
GGTTGGAGGAAAAGCTGGAGCTCTTAATTATGGCGTAAAGCATTCAAAGTACGAGTATCTTGTATTTCTTGATTCAGATG
CACGAGTAGACAAGGATTTCTTAAGTAAACTAGCATTATATGATTTCAATGTAGCTTCTTATAGATTAAGGATTTATAAC
GCTGAAACAGATGTTCAAAGATACTATAAAGAGTTCACTGAAAAAGTTATGGATTCTCTTTTTAAGGTGAGATATTATCT
AGGGTTACCCATTTTTCCAAATGGCTCAGCGTTTTGTATAAGAAAAGATATCTTAATAAAAGTAGGTGGATGGAAAGAAA
ATATCATAACAGAGGACCTAGAATTAGGGATTAGATTATTCCTACATAATTACAAAATCAAATACCTTGATGACATAATA
GTTTACTCTTTAGCTCCATTTACTTTAGATGATCTTTATAAACAAATAGAGAGATGGTCTTATGGTTCAGCCCAATTACT
ACTACAATCCTTTAAGTTATTTAAAAAGGGCATTAGAGGTATTGAAGGAGTACTCTATGCCCAGCAATGGGGCATTTACG
GATTATTTATTTTCATGTTAATTTTACTCTCTTCACTTAACTTTATCTTAAAAATTCCTCTTTTAGTATTCATATTATCT
ATTGTAGTCTATGGAATGTCTGTTTCCATATATGCATTAGTATATAAACAAAAAGTTAATAATTACAAGTTGCCTTTAGT
GATATTAAATGCTTCAATAGCAGGGTATTGTAAAGGTCTAATTAGACTCCCTTTTAAATGGACGATTACACCAAAAGAAA
TGGAAAAAGAAGTTAAGAAGGAAAAAATAAAGGTTTGGATAACTATTCCTCTTCTATTTTCATTTTTAAATATAATATTC
GGAAATATTTTACCATCAATTATACTATTGTTTTTTAGTATTATGGAGTCTGTTGTTTGA

Upstream 100 bases:

>100_bases
AAGAACTTGAGCCAGGTAAATGGGTTAAGATATCTGGTTGGGGAGGAGTTTCGGAGGCTAAAACTAGAATTAATGAAGCC
ATAAAAAGGGCAAATTCAAA

Downstream 100 bases:

>100_bases
TTCCCACCATAGCTTGGACTTCTCTCATAGCTTCTGCTGGTCTTAAACTATACTTAATTATGTACTTCTTCAGTAGCTTG
TAACTTTCTTTACTTTGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: PGA synthase; Poly-beta-1,6-GlcNAc synthase; Biofilm PGA synthesis protein PgaC; N-acetylglucosaminyltransferase PgaC [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNIFSLLLILSAILPSVWNLLQSYYYSKHQINVYEPQNKSQKGFSIIVAEKNESKKTIEGLIHNLLDINYEKYEIIIISD
DPKEKFEEKYREYMNIEKLKILHRNNPVGGKAGALNYGVKHSKYEYLVFLDSDARVDKDFLSKLALYDFNVASYRLRIYN
AETDVQRYYKEFTEKVMDSLFKVRYYLGLPIFPNGSAFCIRKDILIKVGGWKENIITEDLELGIRLFLHNYKIKYLDDII
VYSLAPFTLDDLYKQIERWSYGSAQLLLQSFKLFKKGIRGIEGVLYAQQWGIYGLFIFMLILLSSLNFILKIPLLVFILS
IVVYGMSVSIYALVYKQKVNNYKLPLVILNASIAGYCKGLIRLPFKWTITPKEMEKEVKKEKIKVWITIPLLFSFLNIIF
GNILPSIILLFFSIMESVV

Sequences:

>Translated_419_residues
MNIFSLLLILSAILPSVWNLLQSYYYSKHQINVYEPQNKSQKGFSIIVAEKNESKKTIEGLIHNLLDINYEKYEIIIISD
DPKEKFEEKYREYMNIEKLKILHRNNPVGGKAGALNYGVKHSKYEYLVFLDSDARVDKDFLSKLALYDFNVASYRLRIYN
AETDVQRYYKEFTEKVMDSLFKVRYYLGLPIFPNGSAFCIRKDILIKVGGWKENIITEDLELGIRLFLHNYKIKYLDDII
VYSLAPFTLDDLYKQIERWSYGSAQLLLQSFKLFKKGIRGIEGVLYAQQWGIYGLFIFMLILLSSLNFILKIPLLVFILS
IVVYGMSVSIYALVYKQKVNNYKLPLVILNASIAGYCKGLIRLPFKWTITPKEMEKEVKKEKIKVWITIPLLFSFLNIIF
GNILPSIILLFFSIMESVV
>Mature_419_residues
MNIFSLLLILSAILPSVWNLLQSYYYSKHQINVYEPQNKSQKGFSIIVAEKNESKKTIEGLIHNLLDINYEKYEIIIISD
DPKEKFEEKYREYMNIEKLKILHRNNPVGGKAGALNYGVKHSKYEYLVFLDSDARVDKDFLSKLALYDFNVASYRLRIYN
AETDVQRYYKEFTEKVMDSLFKVRYYLGLPIFPNGSAFCIRKDILIKVGGWKENIITEDLELGIRLFLHNYKIKYLDDII
VYSLAPFTLDDLYKQIERWSYGSAQLLLQSFKLFKKGIRGIEGVLYAQQWGIYGLFIFMLILLSSLNFILKIPLLVFILS
IVVYGMSVSIYALVYKQKVNNYKLPLVILNASIAGYCKGLIRLPFKWTITPKEMEKEVKKEKIKVWITIPLLFSFLNIIF
GNILPSIILLFFSIMESVV

Specific function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1,6- N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=254, Percent_Identity=30.3149606299213, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 48939; Mature: 48939

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFSLLLILSAILPSVWNLLQSYYYSKHQINVYEPQNKSQKGFSIIVAEKNESKKTIEG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHH
LIHNLLDINYEKYEIIIISDDPKEKFEEKYREYMNIEKLKILHRNNPVGGKAGALNYGVK
HHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCHHHHHEEECCCCCCCCCCCCCCCCC
HSKYEYLVFLDSDARVDKDFLSKLALYDFNVASYRLRIYNAETDVQRYYKEFTEKVMDSL
CCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHH
FKVRYYLGLPIFPNGSAFCIRKDILIKVGGWKENIITEDLELGIRLFLHNYKIKYLDDII
HHHHHHHCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VYSLAPFTLDDLYKQIERWSYGSAQLLLQSFKLFKKGIRGIEGVLYAQQWGIYGLFIFML
HHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ILLSSLNFILKIPLLVFILSIVVYGMSVSIYALVYKQKVNNYKLPLVILNASIAGYCKGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHH
IRLPFKWTITPKEMEKEVKKEKIKVWITIPLLFSFLNIIFGNILPSIILLFFSIMESVV
HCCCEEEEECHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIFSLLLILSAILPSVWNLLQSYYYSKHQINVYEPQNKSQKGFSIIVAEKNESKKTIEG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCHHHHHH
LIHNLLDINYEKYEIIIISDDPKEKFEEKYREYMNIEKLKILHRNNPVGGKAGALNYGVK
HHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCHHHHHEEECCCCCCCCCCCCCCCCC
HSKYEYLVFLDSDARVDKDFLSKLALYDFNVASYRLRIYNAETDVQRYYKEFTEKVMDSL
CCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHH
FKVRYYLGLPIFPNGSAFCIRKDILIKVGGWKENIITEDLELGIRLFLHNYKIKYLDDII
HHHHHHHCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VYSLAPFTLDDLYKQIERWSYGSAQLLLQSFKLFKKGIRGIEGVLYAQQWGIYGLFIFML
HHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ILLSSLNFILKIPLLVFILSIVVYGMSVSIYALVYKQKVNNYKLPLVILNASIAGYCKGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHH
IRLPFKWTITPKEMEKEVKKEKIKVWITIPLLFSFLNIIFGNILPSIILLFFSIMESVV
HCCCEEEEECHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]