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The map label for this gene is yleA [C]

Identifier: 15920732

GI number: 15920732

Start: 511999

End: 513255

Strand: Reverse

Name: yleA [C]

Synonym: ST0515

Alternate gene names: 15920732

Gene position: 513255-511999 (Counterclockwise)

Preceding gene: 15920740

Following gene: 15920731

Centisome position: 19.05

GC content: 31.82

Gene sequence:

>1257_bases
GTGAAGGTTTATATTGAAACATATGGTTGTGCACTTAATAAAGGAGATTCATACATAATGATGACTTTATTAAAAGATAG
AGGGCATGATATAGTTGACAGTTATAATCAGGCTGATGTAATAGTTCTGAATACTTGCGCTGTTAGATTAGAAACAGAAG
AAAGAATGAAGCAAAGGATAAAGGAATTGAAAAAAATTGGAAAGAAACTAATAATAGCTGGGTGTTTGGTTAGCTCTCAA
CCAGCATTAGTAATGAGCCTAGCACCTGAAAGTAGTATTGTTGGAGCACAAAGTATAGATAAAATAGTTGAAGCGGTTGA
AAGTAACAAGAGAGGGATATTTCTTGAAGAAAGTAAAGAATTAGTCACGCCTAGAATATTTGAAGGTAAAATTTCAATAA
TACCAATTGCTGATGGTTGTGCTGGAGATTGTAATTTTTGTATAACTAAATTAGCTAGAAAGAAACTAAGAAGTTATCCT
CCAAGAAACATAGTAAATGCCGTTAAAGAGGCTGTTCAGAAAGGTGCTGTAGAAATAGAACTTACAGCTCAAGATACGGC
CGCTTACGGATTGGATATCAACTACAACTTAGTAGAATTACTGAAAGAAATATTAGAAATAGAAGGGAATTATATGATAA
GAATAGGTATGATGACCCCAGAATTAGCTTTTAAACAAATTGATGAGATATTAGAAATAATTAAAGATAAGAGAGTATAT
AAGTTCTTACACTTACCCGTACAAAGCGGAGATGATAGAGTTCTGAAGCTAATGAATAGAAAATATACCGTTGATGAATA
TAGAGAGTTAGTTAAGGAAATAAGAGACAAAATACCAATAGTTAACATAACTACGGACATTATAATTGGTCATCCAGGAG
AAGATGATGAAGCTTTTCAGAATACAATAAATCTTATTAAAGAAATAAAGTTTGAAAGAATACACCTAGCAATGTATTCA
ATACGTCCTAATACGAGAAGCGCATCAATGCCACAAGTGCCAGATTCTATAAAGAAGGAGCGAATGAAAATTGCTAATGA
AGTGTATGAAGAGGTAGCATATTCTGTTCACTCTGAATATTTAGGTTCAAATGCTTTAGTTTTAACTACTGAATTAGGTA
GAAAAGGCTCAATAATAGGAAGAACTATTAATTATATCCCAGTCGTAATTAAGGATTATGATAAATTAGGTGAGTGGATT
AACGTAAAAATTACTGAGGCATCATTTTTTGATTTAAGAGGAAAATTTATTCAATAA

Upstream 100 bases:

>100_bases
GGTAGTTTTGAATACAATCTGTCCAATAGTTTAATATACTCTTCTTCTGTAGACACAAGTAATCTTAAGAGGTTGAAGTA
TAAATTACTTATGATTAGTT

Downstream 100 bases:

>100_bases
CGAGACAAATTCAAATGCATAAAAATTTAAAATAGTTTAAACAAAGTGATTAATATGGATGCATATATTGTTTCCGCTGT
AAGAACTCCTATAGGAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKVYIETYGCALNKGDSYIMMTLLKDRGHDIVDSYNQADVIVLNTCAVRLETEERMKQRIKELKKIGKKLIIAGCLVSSQ
PALVMSLAPESSIVGAQSIDKIVEAVESNKRGIFLEESKELVTPRIFEGKISIIPIADGCAGDCNFCITKLARKKLRSYP
PRNIVNAVKEAVQKGAVEIELTAQDTAAYGLDINYNLVELLKEILEIEGNYMIRIGMMTPELAFKQIDEILEIIKDKRVY
KFLHLPVQSGDDRVLKLMNRKYTVDEYRELVKEIRDKIPIVNITTDIIIGHPGEDDEAFQNTINLIKEIKFERIHLAMYS
IRPNTRSASMPQVPDSIKKERMKIANEVYEEVAYSVHSEYLGSNALVLTTELGRKGSIIGRTINYIPVVIKDYDKLGEWI
NVKITEASFFDLRGKFIQ

Sequences:

>Translated_418_residues
MKVYIETYGCALNKGDSYIMMTLLKDRGHDIVDSYNQADVIVLNTCAVRLETEERMKQRIKELKKIGKKLIIAGCLVSSQ
PALVMSLAPESSIVGAQSIDKIVEAVESNKRGIFLEESKELVTPRIFEGKISIIPIADGCAGDCNFCITKLARKKLRSYP
PRNIVNAVKEAVQKGAVEIELTAQDTAAYGLDINYNLVELLKEILEIEGNYMIRIGMMTPELAFKQIDEILEIIKDKRVY
KFLHLPVQSGDDRVLKLMNRKYTVDEYRELVKEIRDKIPIVNITTDIIIGHPGEDDEAFQNTINLIKEIKFERIHLAMYS
IRPNTRSASMPQVPDSIKKERMKIANEVYEEVAYSVHSEYLGSNALVLTTELGRKGSIIGRTINYIPVVIKDYDKLGEWI
NVKITEASFFDLRGKFIQ
>Mature_418_residues
MKVYIETYGCALNKGDSYIMMTLLKDRGHDIVDSYNQADVIVLNTCAVRLETEERMKQRIKELKKIGKKLIIAGCLVSSQ
PALVMSLAPESSIVGAQSIDKIVEAVESNKRGIFLEESKELVTPRIFEGKISIIPIADGCAGDCNFCITKLARKKLRSYP
PRNIVNAVKEAVQKGAVEIELTAQDTAAYGLDINYNLVELLKEILEIEGNYMIRIGMMTPELAFKQIDEILEIIKDKRVY
KFLHLPVQSGDDRVLKLMNRKYTVDEYRELVKEIRDKIPIVNITTDIIIGHPGEDDEAFQNTINLIKEIKFERIHLAMYS
IRPNTRSASMPQVPDSIKKERMKIANEVYEEVAYSVHSEYLGSNALVLTTELGRKGSIIGRTINYIPVVIKDYDKLGEWI
NVKITEASFFDLRGKFIQ

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=385, Percent_Identity=37.6623376623377, Blast_Score=258, Evalue=5e-69,
Organism=Homo sapiens, GI28872782, Length=478, Percent_Identity=26.5690376569038, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI28872784, Length=478, Percent_Identity=26.5690376569038, Blast_Score=170, Evalue=3e-42,
Organism=Escherichia coli, GI1786882, Length=443, Percent_Identity=30.9255079006772, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787057, Length=440, Percent_Identity=26.5909090909091, Blast_Score=167, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71996771, Length=356, Percent_Identity=31.4606741573034, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553146, Length=459, Percent_Identity=26.1437908496732, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI19922432, Length=439, Percent_Identity=33.4851936218679, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI21356207, Length=476, Percent_Identity=28.5714285714286, Blast_Score=168, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47400; Mature: 47400

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYIETYGCALNKGDSYIMMTLLKDRGHDIVDSYNQADVIVLNTCAVRLETEERMKQRI
CEEEEEECCCEECCCCCEEEEEEHHHCCCHHHHCCCCCCEEEEEEEEEEECHHHHHHHHH
KELKKIGKKLIIAGCLVSSQPALVMSLAPESSIVGAQSIDKIVEAVESNKRGIFLEESKE
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCC
LVTPRIFEGKISIIPIADGCAGDCNFCITKLARKKLRSYPPRNIVNAVKEAVQKGAVEIE
CCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEE
LTAQDTAAYGLDINYNLVELLKEILEIEGNYMIRIGMMTPELAFKQIDEILEIIKDKRVY
EEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHE
KFLHLPVQSGDDRVLKLMNRKYTVDEYRELVKEIRDKIPIVNITTDIIIGHPGEDDEAFQ
EHEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHH
NTINLIKEIKFERIHLAMYSIRPNTRSASMPQVPDSIKKERMKIANEVYEEVAYSVHSEY
HHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSNALVLTTELGRKGSIIGRTINYIPVVIKDYDKLGEWINVKITEASFFDLRGKFIQ
HCCCEEEEEECCCCCCCEECCCHHHEEEEEECHHHCCCEEEEEEECCCEECCCCCCCC
>Mature Secondary Structure
MKVYIETYGCALNKGDSYIMMTLLKDRGHDIVDSYNQADVIVLNTCAVRLETEERMKQRI
CEEEEEECCCEECCCCCEEEEEEHHHCCCHHHHCCCCCCEEEEEEEEEEECHHHHHHHHH
KELKKIGKKLIIAGCLVSSQPALVMSLAPESSIVGAQSIDKIVEAVESNKRGIFLEESKE
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCC
LVTPRIFEGKISIIPIADGCAGDCNFCITKLARKKLRSYPPRNIVNAVKEAVQKGAVEIE
CCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEE
LTAQDTAAYGLDINYNLVELLKEILEIEGNYMIRIGMMTPELAFKQIDEILEIIKDKRVY
EEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHE
KFLHLPVQSGDDRVLKLMNRKYTVDEYRELVKEIRDKIPIVNITTDIIIGHPGEDDEAFQ
EHEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHH
NTINLIKEIKFERIHLAMYSIRPNTRSASMPQVPDSIKKERMKIANEVYEEVAYSVHSEY
HHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSNALVLTTELGRKGSIIGRTINYIPVVIKDYDKLGEWINVKITEASFFDLRGKFIQ
HCCCEEEEEECCCCCCCEECCCHHHEEEEEECHHHCCCEEEEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]