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The map label for this gene is ppa [H]

Identifier: 15920741

GI number: 15920741

Start: 521352

End: 521876

Strand: Reverse

Name: ppa [H]

Synonym: ST0524

Alternate gene names: 15920741

Gene position: 521876-521352 (Counterclockwise)

Preceding gene: 15920742

Following gene: 15920740

Centisome position: 19.37

GC content: 34.48

Gene sequence:

>525_bases
GTGAAAATGAAATTAAGCCCAGGTAAAAAGGCACCAGATGAAGTAAATGTTCTAATAGAGATACCTTTAGGATCAAATAT
AAAATATGAGTACGATGAAGAAGAAGAAGTAGTGAAAGTAGATAGAATCCTTTACACCTCGATGGTTTATCCATTTAATT
ATGGCTTTATACCTGGTACATTAGAAGAAGATGGAGACCCCTTAGATGTATTAGTAATTAGCAATTATCCATTACTACCA
GGAACGGCTATAGAAGTTAGACCTATAGGAATACTCTATATGAGGGATGAAGAAGGAGAAGACGCAAAAATTATTGCAGT
GCCAAAAGATAAAGTAGACCCGACATTTTCAAATATAAAGGATATAATTGATTTACCTCAAGCTATTAAAGACAAGATAA
ACCACTTCTTCGAACACTATAAAGAACTTGAGCCAGGTAAATGGGTTAAGATATCTGGTTGGGGAGGAGTTTCGGAGGCT
AAAACTAGAATTAATGAAGCCATAAAAAGGGCAAATTCAAAATGA

Upstream 100 bases:

>100_bases
GAAATTGAAAACCTCATGAAGGATGAGAAATTATCTTTGATTATTAATGAGATAAATAACTTGATAAAGAATATAAATGG
CTAATGAAATCATCTTTTGA

Downstream 100 bases:

>100_bases
ATATTTTTTCTTTGTTACTAATTTTATCTGCTATATTACCATCTGTTTGGAATCTTTTACAGTCTTATTATTACTCAAAA
CATCAAATTAACGTTTACGA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKMKLSPGKKAPDEVNVLIEIPLGSNIKYEYDEEEEVVKVDRILYTSMVYPFNYGFIPGTLEEDGDPLDVLVISNYPLLP
GTAIEVRPIGILYMRDEEGEDAKIIAVPKDKVDPTFSNIKDIIDLPQAIKDKINHFFEHYKELEPGKWVKISGWGGVSEA
KTRINEAIKRANSK

Sequences:

>Translated_174_residues
MKMKLSPGKKAPDEVNVLIEIPLGSNIKYEYDEEEEVVKVDRILYTSMVYPFNYGFIPGTLEEDGDPLDVLVISNYPLLP
GTAIEVRPIGILYMRDEEGEDAKIIAVPKDKVDPTFSNIKDIIDLPQAIKDKINHFFEHYKELEPGKWVKISGWGGVSEA
KTRINEAIKRANSK
>Mature_174_residues
MKMKLSPGKKAPDEVNVLIEIPLGSNIKYEYDEEEEVVKVDRILYTSMVYPFNYGFIPGTLEEDGDPLDVLVISNYPLLP
GTAIEVRPIGILYMRDEEGEDAKIIAVPKDKVDPTFSNIKDIIDLPQAIKDKINHFFEHYKELEPGKWVKISGWGGVSEA
KTRINEAIKRANSK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=173, Percent_Identity=50.2890173410405, Blast_Score=180, Evalue=5e-47,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19695; Mature: 19695

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKLSPGKKAPDEVNVLIEIPLGSNIKYEYDEEEEVVKVDRILYTSMVYPFNYGFIPGT
CCCCCCCCCCCCCCEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
LEEDGDPLDVLVISNYPLLPGTAIEVRPIGILYMRDEEGEDAKIIAVPKDKVDPTFSNIK
CCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCHHHHH
DIIDLPQAIKDKINHFFEHYKELEPGKWVKISGWGGVSEAKTRINEAIKRANSK
HHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKMKLSPGKKAPDEVNVLIEIPLGSNIKYEYDEEEEVVKVDRILYTSMVYPFNYGFIPGT
CCCCCCCCCCCCCCEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
LEEDGDPLDVLVISNYPLLPGTAIEVRPIGILYMRDEEGEDAKIIAVPKDKVDPTFSNIK
CCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCHHHHH
DIIDLPQAIKDKINHFFEHYKELEPGKWVKISGWGGVSEAKTRINEAIKRANSK
HHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]