Click here to switch to the map view.

The map label for this gene is 159041807

Identifier: 159041807

GI number: 159041807

Start: 1312451

End: 1313593

Strand: Reverse

Name: 159041807

Synonym: Cmaq_1242

Alternate gene names: NA

Gene position: 1313593-1312451 (Counterclockwise)

Preceding gene: 159041809

Following gene: 159041806

Centisome position: 63.23

GC content: 47.16

Gene sequence:

>1143_bases
ATGAGTATTTCGGCATTAGGCTATATAAATGGAGTACACATTATTCCCCCAGGCAGGTATTATGATAAGGGTTATAGGGA
ATTATTCGCTGAGGCTGCCTTAAAGGCTCTTGAATCTGCAGGTAACCCTGACATTAAGGCAATATACATTGCCTCAGCCC
TATCTGAACTTACCGGTGAGCAGATGGCTATAGGTAACGTCCTTAGGGATTACTCAGGCATTAAGAATGCCCCATCCATA
AGGGTTGAGAATGGTGATGGCTCAGGGGGCTTCGCATTCATGGTTGCTTTAAACCACGTGGCATCAATGAGTAATGGATG
CGTACTACTGGTTGGTGTTGATAAGCCTCATGAGGTTACTTCACTTAAGCAGAATAAGTACGCCTCATACCTACTTGACT
CCGATTACGAATCATACTTCGGAGCAACCCCAGTGGTCTTGGCTGCATTAATGGCTAAGCAGTACCTGAGGAATTATGAG
TATAAGTATGAGGACTTAGCCACATGGGCTATTAAAATGCATGAGAGGGGTGCGAAGAATCCCTTCGCCTACTTTAAGAG
GGCGGCTAAGCTAAAGGATGTTCTGGATTCCGAGCTTGTTGCAGACCCATTAAGGCTCTACGATGTATCACCCTTCGTTG
ACGGCGCAGCGGCCCTAGTACTCTGCAGTAAACCTAATGCCAGGGATCAGGCAGTGGGGGTGTTGGGTTACGGGTTCGGT
GCATCAAACTCATACTTCGCCTCAAGGAACGACTACACGGTATTAATGTCTGTGACTGAGGCTGTTAAGGCAATTAACCC
GCTCAGTGACTTCAACGGTATAGTGAGTGTCCACGATACTTATAGTATACTCGGTGTATTGGCGTTGGAATCCCTGGGAT
TATGCAAGAGGGGGAGTGCCTTAAGGCTCCTTAATGAGGGTTACTTTGACCCAGGGGGTAAGGTTATGGTTAACTTAGAC
GGTGGATTAAAGGCTGTGGGTAATTCAATGGGTGCCTCAGGTGTTTACCAATTAGCCAGCGTCACAATGCAGCTTAGGGG
TGATAAACCATTTAACGGCCTAAACGCCGAGGCAGCGGTGGTTGAGGATATGGTTGGTGTGGATCAGGAGAGTGTAGTCT
TCATGCTTAAGGTGGTGAAGTAG

Upstream 100 bases:

>100_bases
GCAATGCATCAAGTAACCTAATGCCATAATGATAGTGCATGCCCCAGGGACCCTAAATAGGGTGTAATATTTATTAAGCT
TTATGTGTAAGGGAAAGTCG

Downstream 100 bases:

>100_bases
CATGGTTGATCAATCCCTATCAGTACCGAAGTACTGGAGGAGGATACCCCAGTACTATAGGCTCACTGCCCTTAAATGCA
GGAAATGCGGTAAGGTTTAC

Product: acetyl-CoA C-acyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSISALGYINGVHIIPPGRYYDKGYRELFAEAALKALESAGNPDIKAIYIASALSELTGEQMAIGNVLRDYSGIKNAPSI
RVENGDGSGGFAFMVALNHVASMSNGCVLLVGVDKPHEVTSLKQNKYASYLLDSDYESYFGATPVVLAALMAKQYLRNYE
YKYEDLATWAIKMHERGAKNPFAYFKRAAKLKDVLDSELVADPLRLYDVSPFVDGAAALVLCSKPNARDQAVGVLGYGFG
ASNSYFASRNDYTVLMSVTEAVKAINPLSDFNGIVSVHDTYSILGVLALESLGLCKRGSALRLLNEGYFDPGGKVMVNLD
GGLKAVGNSMGASGVYQLASVTMQLRGDKPFNGLNAEAAVVEDMVGVDQESVVFMLKVVK

Sequences:

>Translated_380_residues
MSISALGYINGVHIIPPGRYYDKGYRELFAEAALKALESAGNPDIKAIYIASALSELTGEQMAIGNVLRDYSGIKNAPSI
RVENGDGSGGFAFMVALNHVASMSNGCVLLVGVDKPHEVTSLKQNKYASYLLDSDYESYFGATPVVLAALMAKQYLRNYE
YKYEDLATWAIKMHERGAKNPFAYFKRAAKLKDVLDSELVADPLRLYDVSPFVDGAAALVLCSKPNARDQAVGVLGYGFG
ASNSYFASRNDYTVLMSVTEAVKAINPLSDFNGIVSVHDTYSILGVLALESLGLCKRGSALRLLNEGYFDPGGKVMVNLD
GGLKAVGNSMGASGVYQLASVTMQLRGDKPFNGLNAEAAVVEDMVGVDQESVVFMLKVVK
>Mature_379_residues
SISALGYINGVHIIPPGRYYDKGYRELFAEAALKALESAGNPDIKAIYIASALSELTGEQMAIGNVLRDYSGIKNAPSIR
VENGDGSGGFAFMVALNHVASMSNGCVLLVGVDKPHEVTSLKQNKYASYLLDSDYESYFGATPVVLAALMAKQYLRNYEY
KYEDLATWAIKMHERGAKNPFAYFKRAAKLKDVLDSELVADPLRLYDVSPFVDGAAALVLCSKPNARDQAVGVLGYGFGA
SNSYFASRNDYTVLMSVTEAVKAINPLSDFNGIVSVHDTYSILGVLALESLGLCKRGSALRLLNEGYFDPGGKVMVNLDG
GLKAVGNSMGASGVYQLASVTMQLRGDKPFNGLNAEAAVVEDMVGVDQESVVFMLKVVK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=389, Percent_Identity=25.706940874036, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI302344760, Length=347, Percent_Identity=25.0720461095101, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI302344767, Length=323, Percent_Identity=25.6965944272446, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI302344762, Length=294, Percent_Identity=25.8503401360544, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI55956775, Length=196, Percent_Identity=29.0816326530612, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17537653, Length=373, Percent_Identity=25.4691689008043, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19921506, Length=358, Percent_Identity=29.0502793296089, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24585051, Length=370, Percent_Identity=28.9189189189189, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 40848; Mature: 40717

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISALGYINGVHIIPPGRYYDKGYRELFAEAALKALESAGNPDIKAIYIASALSELTGE
CCCCCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCC
QMAIGNVLRDYSGIKNAPSIRVENGDGSGGFAFMVALNHVASMSNGCVLLVGVDKPHEVT
HHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHH
SLKQNKYASYLLDSDYESYFGATPVVLAALMAKQYLRNYEYKYEDLATWAIKMHERGAKN
HHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
PFAYFKRAAKLKDVLDSELVADPLRLYDVSPFVDGAAALVLCSKPNARDQAVGVLGYGFG
HHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCEEEEEECCCCCCCCEEEEEEECCC
ASNSYFASRNDYTVLMSVTEAVKAINPLSDFNGIVSVHDTYSILGVLALESLGLCKRGSA
CCCCEEECCCCCEEEEEHHHHHHHHCCHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCCH
LRLLNEGYFDPGGKVMVNLDGGLKAVGNSMGASGVYQLASVTMQLRGDKPFNGLNAEAAV
HHHHHCCCCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCCHHHH
VEDMVGVDQESVVFMLKVVK
HHHHHCCCHHHHEEEEEECC
>Mature Secondary Structure 
SISALGYINGVHIIPPGRYYDKGYRELFAEAALKALESAGNPDIKAIYIASALSELTGE
CCCCEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCC
QMAIGNVLRDYSGIKNAPSIRVENGDGSGGFAFMVALNHVASMSNGCVLLVGVDKPHEVT
HHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHH
SLKQNKYASYLLDSDYESYFGATPVVLAALMAKQYLRNYEYKYEDLATWAIKMHERGAKN
HHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
PFAYFKRAAKLKDVLDSELVADPLRLYDVSPFVDGAAALVLCSKPNARDQAVGVLGYGFG
HHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCEEEEEECCCCCCCCEEEEEEECCC
ASNSYFASRNDYTVLMSVTEAVKAINPLSDFNGIVSVHDTYSILGVLALESLGLCKRGSA
CCCCEEECCCCCEEEEEHHHHHHHHCCHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCCH
LRLLNEGYFDPGGKVMVNLDGGLKAVGNSMGASGVYQLASVTMQLRGDKPFNGLNAEAAV
HHHHHCCCCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCCHHHH
VEDMVGVDQESVVFMLKVVK
HHHHHCCCHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]