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The map label for this gene is 159041416

Identifier: 159041416

GI number: 159041416

Start: 887149

End: 888006

Strand: Reverse

Name: 159041416

Synonym: Cmaq_0843

Alternate gene names: NA

Gene position: 888006-887149 (Counterclockwise)

Preceding gene: 159041417

Following gene: 159041415

Centisome position: 42.74

GC content: 43.47

Gene sequence:

>858_bases
GTGGAGGTAAGTGAGGAGAGGGTCATTAAGCTAAGCACTGTGTTAAGGGAATTAAGCCTAAGCGATGTATTAGCCTTCGA
GGAGAGGGATCCACAATTCATTGTTGTTAAGGAACTGTGCACGGCATTAAATAACCCAGGACTTGTGGCGGTATTGGTTG
CTATGAACTCCATTGTAAGCTACATGTTAACCGGCAGGGGGGAGAGGCATTGGAGCTACTTCAGTGAATACTTCAGTCAT
AATAAGCCTAGTGACCTATGTAGGGATTTTAAGGCATACGTGGTGAAAAGCCCCTACTTGGCGAGGGGTAGGGAAGTTAA
GGTTGATAGGATTGATAGGTTCTGTAGGGCTAAACTCCATGAAAGGTTAATGGGTTTAACTAATTTAAATGAGGCATGGA
GTCTCTTAGCCGGTGGACTACATTCACCCATTAATAGTAAGACCATAGTCTTCGCAGTTAAGATGCTTTACTACGCCTAC
AGGGCATGTGGTATTAACGTAAAACCCCCTGAGGATTTACCAATACCAGTGGATTACAGGATAGCTACCTTGACTAAGTG
CAGCGGTTTAATTAATGCTGAGGCTAAGGTGCTTGCGGCTAAGCAGAACCTAGTACAGGAGACTTGGGGAAGGGTTGCGG
AGCTCTCTGGGATACCTCAAGTTAACCTTGATGCGCTACTATGGGTTATTGGTGGCGCATTAATATACAGTAACTTCAAC
GTTAATTCAGCCCTACGTAAGTTAATGGAGGATTCATTAATACCACCAGGTAAGGCTACTGTTTTTAAGGAGCTAGTGAC
TGAATTAAGTAGAGAATGCTCAAGAGGGGCAGAAACGTTTAAATATAACAATTCATAA

Upstream 100 bases:

>100_bases
TACACAATAGGTAAACCATTACTGTTCATTGATGTTGGGCAATTAGCCTTAATTTACGCACTCTGGAGGGCTTTTAAAAA
CAACCTAATCAAGATTAAGC

Downstream 100 bases:

>100_bases
TATTTTATAGTAGATTGAAGTATATGGATGAGAAGCTGTTACCTCCAGGGGAGGTATGCAGACGGCTGGGTATTCATTAT
GTTACTTTGAAGAGGTGGAT

Product: N-glycosylase/DNA lyase

Products: NA

Alternate protein names: 8-oxoguanine DNA glycosylase; AGOG; DNA-(apurinic or apyrimidinic site) lyase; AP lyase; Pa-AGOG [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MEVSEERVIKLSTVLRELSLSDVLAFEERDPQFIVVKELCTALNNPGLVAVLVAMNSIVSYMLTGRGERHWSYFSEYFSH
NKPSDLCRDFKAYVVKSPYLARGREVKVDRIDRFCRAKLHERLMGLTNLNEAWSLLAGGLHSPINSKTIVFAVKMLYYAY
RACGINVKPPEDLPIPVDYRIATLTKCSGLINAEAKVLAAKQNLVQETWGRVAELSGIPQVNLDALLWVIGGALIYSNFN
VNSALRKLMEDSLIPPGKATVFKELVTELSRECSRGAETFKYNNS

Sequences:

>Translated_285_residues
MEVSEERVIKLSTVLRELSLSDVLAFEERDPQFIVVKELCTALNNPGLVAVLVAMNSIVSYMLTGRGERHWSYFSEYFSH
NKPSDLCRDFKAYVVKSPYLARGREVKVDRIDRFCRAKLHERLMGLTNLNEAWSLLAGGLHSPINSKTIVFAVKMLYYAY
RACGINVKPPEDLPIPVDYRIATLTKCSGLINAEAKVLAAKQNLVQETWGRVAELSGIPQVNLDALLWVIGGALIYSNFN
VNSALRKLMEDSLIPPGKATVFKELVTELSRECSRGAETFKYNNS
>Mature_285_residues
MEVSEERVIKLSTVLRELSLSDVLAFEERDPQFIVVKELCTALNNPGLVAVLVAMNSIVSYMLTGRGERHWSYFSEYFSH
NKPSDLCRDFKAYVVKSPYLARGREVKVDRIDRFCRAKLHERLMGLTNLNEAWSLLAGGLHSPINSKTIVFAVKMLYYAY
RACGINVKPPEDLPIPVDYRIATLTKCSGLINAEAKVLAAKQNLVQETWGRVAELSGIPQVNLDALLWVIGGALIYSNFN
VNSALRKLMEDSLIPPGKATVFKELVTELSRECSRGAETFKYNNS

Specific function: DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates [H]

COG id: COG4047

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR023170
- InterPro:   IPR015254
- InterPro:   IPR016544 [H]

Pfam domain/function: PF09171 DUF1886 [H]

EC number: =4.2.99.18 [H]

Molecular weight: Translated: 31981; Mature: 31981

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVSEERVIKLSTVLRELSLSDVLAFEERDPQFIVVKELCTALNNPGLVAVLVAMNSIVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHH
YMLTGRGERHWSYFSEYFSHNKPSDLCRDFKAYVVKSPYLARGREVKVDRIDRFCRAKLH
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
ERLMGLTNLNEAWSLLAGGLHSPINSKTIVFAVKMLYYAYRACGINVKPPEDLPIPVDYR
HHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
IATLTKCSGLINAEAKVLAAKQNLVQETWGRVAELSGIPQVNLDALLWVIGGALIYSNFN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCC
VNSALRKLMEDSLIPPGKATVFKELVTELSRECSRGAETFKYNNS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCC
>Mature Secondary Structure
MEVSEERVIKLSTVLRELSLSDVLAFEERDPQFIVVKELCTALNNPGLVAVLVAMNSIVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHH
YMLTGRGERHWSYFSEYFSHNKPSDLCRDFKAYVVKSPYLARGREVKVDRIDRFCRAKLH
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
ERLMGLTNLNEAWSLLAGGLHSPINSKTIVFAVKMLYYAYRACGINVKPPEDLPIPVDYR
HHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
IATLTKCSGLINAEAKVLAAKQNLVQETWGRVAELSGIPQVNLDALLWVIGGALIYSNFN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCC
VNSALRKLMEDSLIPPGKATVFKELVTELSRECSRGAETFKYNNS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]