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The map label for this gene is gabT [H]

Identifier: 159041265

GI number: 159041265

Start: 724292

End: 725671

Strand: Reverse

Name: gabT [H]

Synonym: Cmaq_0687

Alternate gene names: 159041265

Gene position: 725671-724292 (Counterclockwise)

Preceding gene: 159041266

Following gene: 159041256

Centisome position: 34.93

GC content: 46.67

Gene sequence:

>1380_bases
ATGCCTAACTGGTACTGGGATGTTAAGCCAAGTGACGTCCCAAGAATAATAGTGGAGCCCCCTGGACCCAGGGCCTTAAG
TATTGTTAAGAGCGATGAGTCACTGATAATGCAGTCCTTTGGGCGATGGTACCCCCTAGTGATTAAGAGGGGATTCGGCC
CAGTGATAGAGGATGTTGACGGTAACCTATACGTGGACTTTAACTCAGGTATAGCAGTCATGAATGTTGGGCACTCCCAC
CCAAGGATTGTTAAGGCTATAAGGAATCAGGCAGGTGAATTCACCCACTACAGTTTAACTGACTTCTACTATGAATTAGC
CGTTAAACACGCCTCAATGTTAATTGAAGTAACCCCAATAAGTGGCGGGAAGAGCGTCTTCTACGCCAATTCAGGTACTG
AGGCGATAGAGGGTTCCCTTAAGATAGCTAGGGGGTATTTCAGGAATCAGAGGCCTTACGTTATGGCCTTCCTAGGTGCA
TTCCACGGTAGGACTTATGGTTCAATGTCCTTAACAGCCAGTAAACCTATTCAGCGATTTGGGTTTAACCCAATGATGCC
TAATGTCATTCACGCACCATACCCGTATCCATACAGGTGCCCCTTCGGTAAGAGGCTGAGTGAGGAGGAGTGTGGCGAGC
AAGCTTTATCGTTCATTGAGGATTGGGTATTCGGTAGGTTAGTTGATCCAAGTGAGGTGGCTGCAGTCTTCATTGAACCC
ATTCAAGGTGAGGGGGGTTACGTTGTACCACCGGTTAACTTCATGAGAGGGTTAAGGAAGATTACTGAGGAGCACGGTAT
AATGCTGGTTGTTGATGAGGTTCAATCAGGCTTCGGTAGAACCGGTAAGTGGTTTGCAGTGGAGCACTTCGGCATTGAAC
CTGACTTAATAGCCATGGCTAAGGCCATAGCGGCTGGCCTACCATTAGGAGCCATTGTGGGTAAGGCTAACTTAATGAAA
CTGCCTAAGGGTTCCCACGCCAATACCTTCGGTGGTAATCCAGTGGCCTTGGCTGCAGGTATTGAGGTGATTAACGTTAT
TAAGGATGAGGACTTACTTACAAACGCCTCAAGGGTTGGGGATTACATTATGAGGAGGTTTAAAGAGGAGACTGATTCAA
GCAGGTTAATTGGTGACGTTAGGGGGCTTGGATTAATGATTGGTGTTGAGTTGGTTAAGAATAAGGTAAGCAAGGAACCT
GCCGTTAAGGAGCTGGGGGAGGTGTTAATGAGATCGTTTAAGAGGGGGGTGGCTGTAATAGGTTCGGGTAAATCAACAAT
AAGGATTGCACCACCCCTTAACATACCCATTGAATTAGCTGAAAAGGCTGTTGACATAATTATTGAATCAATAAGGAGCG
TTGAAAGGGAAACCCCCTAA

Upstream 100 bases:

>100_bases
GGTTGTCAGTCTGTTAACCGGTAAGGTTCTTAAATAATGCTACATAGGTTATATACCCTATTATAGGATACTTTATTAAA
CACCACTGAGGTAACTAAGT

Downstream 100 bases:

>100_bases
CATCTATAAAACCTAGACACCCTTAATTAAACACCGCTATTTAAACCCCTTAAGCATCTTCCCACTGAAAGACGACTTTA
AGCGCATATTGTTAATCCTT

Product: 4-aminobutyrate aminotransferase

Products: NA

Alternate protein names: (S)-3-amino-2-methylpropionate transaminase; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MPNWYWDVKPSDVPRIIVEPPGPRALSIVKSDESLIMQSFGRWYPLVIKRGFGPVIEDVDGNLYVDFNSGIAVMNVGHSH
PRIVKAIRNQAGEFTHYSLTDFYYELAVKHASMLIEVTPISGGKSVFYANSGTEAIEGSLKIARGYFRNQRPYVMAFLGA
FHGRTYGSMSLTASKPIQRFGFNPMMPNVIHAPYPYPYRCPFGKRLSEEECGEQALSFIEDWVFGRLVDPSEVAAVFIEP
IQGEGGYVVPPVNFMRGLRKITEEHGIMLVVDEVQSGFGRTGKWFAVEHFGIEPDLIAMAKAIAAGLPLGAIVGKANLMK
LPKGSHANTFGGNPVALAAGIEVINVIKDEDLLTNASRVGDYIMRRFKEETDSSRLIGDVRGLGLMIGVELVKNKVSKEP
AVKELGEVLMRSFKRGVAVIGSGKSTIRIAPPLNIPIELAEKAVDIIIESIRSVERETP

Sequences:

>Translated_459_residues
MPNWYWDVKPSDVPRIIVEPPGPRALSIVKSDESLIMQSFGRWYPLVIKRGFGPVIEDVDGNLYVDFNSGIAVMNVGHSH
PRIVKAIRNQAGEFTHYSLTDFYYELAVKHASMLIEVTPISGGKSVFYANSGTEAIEGSLKIARGYFRNQRPYVMAFLGA
FHGRTYGSMSLTASKPIQRFGFNPMMPNVIHAPYPYPYRCPFGKRLSEEECGEQALSFIEDWVFGRLVDPSEVAAVFIEP
IQGEGGYVVPPVNFMRGLRKITEEHGIMLVVDEVQSGFGRTGKWFAVEHFGIEPDLIAMAKAIAAGLPLGAIVGKANLMK
LPKGSHANTFGGNPVALAAGIEVINVIKDEDLLTNASRVGDYIMRRFKEETDSSRLIGDVRGLGLMIGVELVKNKVSKEP
AVKELGEVLMRSFKRGVAVIGSGKSTIRIAPPLNIPIELAEKAVDIIIESIRSVERETP
>Mature_458_residues
PNWYWDVKPSDVPRIIVEPPGPRALSIVKSDESLIMQSFGRWYPLVIKRGFGPVIEDVDGNLYVDFNSGIAVMNVGHSHP
RIVKAIRNQAGEFTHYSLTDFYYELAVKHASMLIEVTPISGGKSVFYANSGTEAIEGSLKIARGYFRNQRPYVMAFLGAF
HGRTYGSMSLTASKPIQRFGFNPMMPNVIHAPYPYPYRCPFGKRLSEEECGEQALSFIEDWVFGRLVDPSEVAAVFIEPI
QGEGGYVVPPVNFMRGLRKITEEHGIMLVVDEVQSGFGRTGKWFAVEHFGIEPDLIAMAKAIAAGLPLGAIVGKANLMKL
PKGSHANTFGGNPVALAAGIEVINVIKDEDLLTNASRVGDYIMRRFKEETDSSRLIGDVRGLGLMIGVELVKNKVSKEPA
VKELGEVLMRSFKRGVAVIGSGKSTIRIAPPLNIPIELAEKAVDIIIESIRSVERETP

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=453, Percent_Identity=33.3333333333333, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI4557809, Length=417, Percent_Identity=31.1750599520384, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI37574042, Length=415, Percent_Identity=30.3614457831325, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=29.8611111111111, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=30.46875, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=29.6385542168675, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=31.3253012048193, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI188536080, Length=456, Percent_Identity=28.5087719298246, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI38679950, Length=456, Percent_Identity=28.5087719298246, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI38679946, Length=456, Percent_Identity=28.5087719298246, Blast_Score=146, Evalue=4e-35,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=37.75, Blast_Score=264, Evalue=7e-72,
Organism=Escherichia coli, GI1789016, Length=432, Percent_Identity=34.0277777777778, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI145693181, Length=403, Percent_Identity=33.2506203473945, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788044, Length=426, Percent_Identity=32.1596244131455, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1789759, Length=390, Percent_Identity=33.3333333333333, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=32.0512820512821, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786991, Length=426, Percent_Identity=27.6995305164319, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=33.256351039261, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25144271, Length=422, Percent_Identity=28.1990521327014, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71992977, Length=448, Percent_Identity=30.1339285714286, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17541228, Length=482, Percent_Identity=26.1410788381743, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25144274, Length=300, Percent_Identity=28.6666666666667, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323470, Length=418, Percent_Identity=32.5358851674641, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324432, Length=443, Percent_Identity=32.7313769751693, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6321456, Length=473, Percent_Identity=27.061310782241, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324386, Length=419, Percent_Identity=23.3890214797136, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28574759, Length=429, Percent_Identity=33.7995337995338, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI161085790, Length=437, Percent_Identity=32.7231121281465, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21357415, Length=418, Percent_Identity=30.3827751196172, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=30.2325581395349, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281366494, Length=471, Percent_Identity=26.3269639065817, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24667139, Length=471, Percent_Identity=26.3269639065817, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24667143, Length=471, Percent_Identity=26.3269639065817, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004632
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.19; =2.6.1.22 [H]

Molecular weight: Translated: 50526; Mature: 50395

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNWYWDVKPSDVPRIIVEPPGPRALSIVKSDESLIMQSFGRWYPLVIKRGFGPVIEDVD
CCCCEECCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHCCCEEEEEECCCCCHHCCCC
GNLYVDFNSGIAVMNVGHSHPRIVKAIRNQAGEFTHYSLTDFYYELAVKHASMLIEVTPI
CCEEEEECCCEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCEEEEEEEEC
SGGKSVFYANSGTEAIEGSLKIARGYFRNQRPYVMAFLGAFHGRTYGSMSLTASKPIQRF
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHH
GFNPMMPNVIHAPYPYPYRCPFGKRLSEEECGEQALSFIEDWVFGRLVDPSEVAAVFIEP
CCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEEE
IQGEGGYVVPPVNFMRGLRKITEEHGIMLVVDEVQSGFGRTGKWFAVEHFGIEPDLIAMA
ECCCCCEEECCHHHHHHHHHHHHHCCEEEEEEHHHHCCCCCCCEEEEEECCCCHHHHHHH
KAIAAGLPLGAIVGKANLMKLPKGSHANTFGGNPVALAAGIEVINVIKDEDLLTNASRVG
HHHHHCCCHHHHHCCCHHEECCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHH
DYIMRRFKEETDSSRLIGDVRGLGLMIGVELVKNKVSKEPAVKELGEVLMRSFKRGVAVI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEE
GSGKSTIRIAPPLNIPIELAEKAVDIIIESIRSVERETP
ECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PNWYWDVKPSDVPRIIVEPPGPRALSIVKSDESLIMQSFGRWYPLVIKRGFGPVIEDVD
CCCEECCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHCCCEEEEEECCCCCHHCCCC
GNLYVDFNSGIAVMNVGHSHPRIVKAIRNQAGEFTHYSLTDFYYELAVKHASMLIEVTPI
CCEEEEECCCEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCEEEEEEEEC
SGGKSVFYANSGTEAIEGSLKIARGYFRNQRPYVMAFLGAFHGRTYGSMSLTASKPIQRF
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHH
GFNPMMPNVIHAPYPYPYRCPFGKRLSEEECGEQALSFIEDWVFGRLVDPSEVAAVFIEP
CCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEEEE
IQGEGGYVVPPVNFMRGLRKITEEHGIMLVVDEVQSGFGRTGKWFAVEHFGIEPDLIAMA
ECCCCCEEECCHHHHHHHHHHHHHCCEEEEEEHHHHCCCCCCCEEEEEECCCCHHHHHHH
KAIAAGLPLGAIVGKANLMKLPKGSHANTFGGNPVALAAGIEVINVIKDEDLLTNASRVG
HHHHHCCCHHHHHCCCHHEECCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHH
DYIMRRFKEETDSSRLIGDVRGLGLMIGVELVKNKVSKEPAVKELGEVLMRSFKRGVAVI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEE
GSGKSTIRIAPPLNIPIELAEKAVDIIIESIRSVERETP
ECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]